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The map label for this gene is clpV1 [H]

Identifier: 59711606

GI number: 59711606

Start: 1101851

End: 1104433

Strand: Reverse

Name: clpV1 [H]

Synonym: VF_0999

Alternate gene names: 59711606

Gene position: 1104433-1101851 (Counterclockwise)

Preceding gene: 59711607

Following gene: 59711605

Centisome position: 38.12

GC content: 39.84

Gene sequence:

>2583_bases
ATGATTAACGTAGAACTACCTCAATTAATTAAAACATTAGATAAAGAGTCACACCTTGCGTTAGAGCAAGCCGCACAATT
ATGCGTCACTCGTGGCGGTAATGAAGTGTTATGTGAAGACTTTATTCTTGCGGCACTGAATAATCCACAAAGTTTCTGGA
ATAAAGCTTGTCAACAATACAATGTATCTACTGACGTTTTAATTGAAGCGCTACAACACGGAAGAAAAAGTACCTCATCT
GAAAGTAATCATCCTGTCTTATCAACTGCGTTAATCGAATGGCTTCAAGAAAGTTATCTCTTCTCCATGTTAGAAATGCA
ACTTTCTGAAGTACTCGCAGCAAATTTACTGCTTACTCTCCTTTCCCATCCAAACAAATATGGGCACACCCCCTATTACC
GTGAGTTAAGTGTTATTCCTGTCGCTTCATTAAAACAACAGGTTGAAGGCTTAGTCAGCTGTGCGAATCGAGATTCTCAT
TCCTCTGCTGAACATCAAAATGCACTCGATGCATACACAACCAATTACACACAATTGGCGAAAGATAATAAAATTGATCC
TGTTTTATGCCGAGATTCTGAAATTCGTCAAATGATCGATATTTTAGCTCGTCGCCGTAAAAATAACCCAATGATTGTTG
GCGAAGCAGGGGTTGGTAAAACGGCATTAGTAGAAGGTTTAGCAATAAAAATAGCTCAAGGTGAAGTGCCGGATATGCTT
GAAAATGTCGCCCTTCTCTCTTTAGACCTTGGACTACTTCAAGCAGGAGCAAGCATTAAAGGTGAATTTGAACGTCGCTT
AAATTTGGTTATCACAGCAGTTCAAGAAAGTCCGACGCCTATTATCTTATTTATTGATGAAGCACATACTCTAATTGGTG
CTGGTGGACAAGCAGGTAGCAATGATGCAGCCAATCTTCTAAAACCAGCTCTTGCTCGAGGTGAATTACGCACAATAGGT
GCAACAACGTGGTCTGAATATAAAAAATACATTGAAAAGGATCCTGCACTTGCACGACGTTTCCAACCTGTAAAAGTGAA
CGAACCTAATGTTACTCAAGCCATAACGATTTTACGTGGTCTTGCAGAGCGTTATGAAGAAAGCCACGGTGTTTATGTAA
GAGATGATGCCATTATTGCCGCTGCTGAATTATCTGCACGTTACATTAGCGGTCGCCAACTACCTGATAAAGCAATCGAT
CTTCTTGATACGGCTTGTGCACGTGTGAAGATCAATTTAAAAGCAAAGCCTGAGTCATTAGAAAGGTTATTGCATATTAT
TGCTATTACTCAACGTGAGCTTGATTGTGTATTAAGAGATCAACAAGCTGGGATCAATATTGAAGAAAACACCATCACTC
TGTTGAAAGAAAAACTGTCTCAAACCCACCTTGACGCTGAACAGTTAGAACAAGAATGGCAAACACAAAAAGAATTAGCC
GAAGCGTTACTAACTTCTCGAATTGACATTGCACAATGTAACGATGAAGAAGAAAAGCATCGATTAATTTGCAACCAACA
AGAGATACATCAAGCGCTATCGGATGCACAACATACACACTCTTTAGTCAACTACGAAACCTGCCCATCTTTGGTTGCTG
AGGTAGTATCCCATTGGACAGGCATTCCAATGAGTACATTACAACGTGGACAAGCGACTCAAGTACTTACGATAAAATCA
AAGCTAAAAGAACAAATCAAAGGCCAAGATCAAGCCGTCATCGCCTTAGAAAAAGCAATCCAAGCCACTGCAGCAGGATT
AAACAACCCTAATTCTCCAACTGGTGTATTTCTTTTTGTTGGTCCAAGTGGTGTAGGCAAAACTCAAACCGCTCAAGCCA
TTGCCGATTTAATGTATGGCGGCGAACAATTTCTTACCACCATCAATATGTCAGAGTTTCAAGAAAAACACACCGTATCT
CGCCTAATTGGTTCGCCTCCTGGCTACGTTGGATATGGTGAAGGCGGAGTGTTAACTGAAGCCGTTCGTCAACGCCCTTA
TTCCGTTGTATTACTTGATGAAGTCGAAAAAGCAGATCCTGAAATAATGAACCTTTTCTATCAAATTTTTGATAAAGGCG
TAGCTAATGATGGTGAAGGAAGAGAAATCAACTTCAAACAAACACTAATAATCATGACGTCAAACTTAGCCTCTGATCAA
ATTGAAGCTCTTTGTAATCAAGAAGAAAAACCGACAACTGATGCATTAACTAAAGCCATCCGTCCAACGTTAAATCAGTA
CTTTAAACCAGCCTTAGTCGGACGAATGACCGTTGTCCCATTCTTCCCTCTTGATATGGAAAGTATGGAAGCCCTTGTGG
ATATTCGCCTTAAACAATTAACCGAACAGCTATCATTGCAACAAATCACTCTTCATTATGACGAAGCAATCATTCAACAC
ATTGCTCAAAGTTGTACATTAACTGAAACCGGTGCGAGAAATATTGATGCCATTATTAATGGACAACTAAAACCTGCATT
TTCATCCCAAATACTGCTAGCACTGGCTAGAAAAGAACCATTAACCAGTATTTCTTTATGTATTGATGAAAATGGCCAAG
TCTTTTGCGAGTTTGAGGACTAG

Upstream 100 bases:

>100_bases
CATTAACCTTATCAGTTGATAATGAATGCTGTTTAGGTTGGACGAGTTGGCTAGGTTCAAACCCAAATGAAGGACGTATT
ACACTTTCAGGGAAAACATT

Downstream 100 bases:

>100_bases
CCATCATGCCAGAGCTATTAATGAATATTACTTCAGAACAACAAAGTGACTTTAATAAATTCACTCAATGTTGGTTATCT
GGAATTTTAAAACACAGTGG

Product: ATP-dependent protease subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 860; Mature: 860

Protein sequence:

>860_residues
MINVELPQLIKTLDKESHLALEQAAQLCVTRGGNEVLCEDFILAALNNPQSFWNKACQQYNVSTDVLIEALQHGRKSTSS
ESNHPVLSTALIEWLQESYLFSMLEMQLSEVLAANLLLTLLSHPNKYGHTPYYRELSVIPVASLKQQVEGLVSCANRDSH
SSAEHQNALDAYTTNYTQLAKDNKIDPVLCRDSEIRQMIDILARRRKNNPMIVGEAGVGKTALVEGLAIKIAQGEVPDML
ENVALLSLDLGLLQAGASIKGEFERRLNLVITAVQESPTPIILFIDEAHTLIGAGGQAGSNDAANLLKPALARGELRTIG
ATTWSEYKKYIEKDPALARRFQPVKVNEPNVTQAITILRGLAERYEESHGVYVRDDAIIAAAELSARYISGRQLPDKAID
LLDTACARVKINLKAKPESLERLLHIIAITQRELDCVLRDQQAGINIEENTITLLKEKLSQTHLDAEQLEQEWQTQKELA
EALLTSRIDIAQCNDEEEKHRLICNQQEIHQALSDAQHTHSLVNYETCPSLVAEVVSHWTGIPMSTLQRGQATQVLTIKS
KLKEQIKGQDQAVIALEKAIQATAAGLNNPNSPTGVFLFVGPSGVGKTQTAQAIADLMYGGEQFLTTINMSEFQEKHTVS
RLIGSPPGYVGYGEGGVLTEAVRQRPYSVVLLDEVEKADPEIMNLFYQIFDKGVANDGEGREINFKQTLIIMTSNLASDQ
IEALCNQEEKPTTDALTKAIRPTLNQYFKPALVGRMTVVPFFPLDMESMEALVDIRLKQLTEQLSLQQITLHYDEAIIQH
IAQSCTLTETGARNIDAIINGQLKPAFSSQILLALARKEPLTSISLCIDENGQVFCEFED

Sequences:

>Translated_860_residues
MINVELPQLIKTLDKESHLALEQAAQLCVTRGGNEVLCEDFILAALNNPQSFWNKACQQYNVSTDVLIEALQHGRKSTSS
ESNHPVLSTALIEWLQESYLFSMLEMQLSEVLAANLLLTLLSHPNKYGHTPYYRELSVIPVASLKQQVEGLVSCANRDSH
SSAEHQNALDAYTTNYTQLAKDNKIDPVLCRDSEIRQMIDILARRRKNNPMIVGEAGVGKTALVEGLAIKIAQGEVPDML
ENVALLSLDLGLLQAGASIKGEFERRLNLVITAVQESPTPIILFIDEAHTLIGAGGQAGSNDAANLLKPALARGELRTIG
ATTWSEYKKYIEKDPALARRFQPVKVNEPNVTQAITILRGLAERYEESHGVYVRDDAIIAAAELSARYISGRQLPDKAID
LLDTACARVKINLKAKPESLERLLHIIAITQRELDCVLRDQQAGINIEENTITLLKEKLSQTHLDAEQLEQEWQTQKELA
EALLTSRIDIAQCNDEEEKHRLICNQQEIHQALSDAQHTHSLVNYETCPSLVAEVVSHWTGIPMSTLQRGQATQVLTIKS
KLKEQIKGQDQAVIALEKAIQATAAGLNNPNSPTGVFLFVGPSGVGKTQTAQAIADLMYGGEQFLTTINMSEFQEKHTVS
RLIGSPPGYVGYGEGGVLTEAVRQRPYSVVLLDEVEKADPEIMNLFYQIFDKGVANDGEGREINFKQTLIIMTSNLASDQ
IEALCNQEEKPTTDALTKAIRPTLNQYFKPALVGRMTVVPFFPLDMESMEALVDIRLKQLTEQLSLQQITLHYDEAIIQH
IAQSCTLTETGARNIDAIINGQLKPAFSSQILLALARKEPLTSISLCIDENGQVFCEFED
>Mature_860_residues
MINVELPQLIKTLDKESHLALEQAAQLCVTRGGNEVLCEDFILAALNNPQSFWNKACQQYNVSTDVLIEALQHGRKSTSS
ESNHPVLSTALIEWLQESYLFSMLEMQLSEVLAANLLLTLLSHPNKYGHTPYYRELSVIPVASLKQQVEGLVSCANRDSH
SSAEHQNALDAYTTNYTQLAKDNKIDPVLCRDSEIRQMIDILARRRKNNPMIVGEAGVGKTALVEGLAIKIAQGEVPDML
ENVALLSLDLGLLQAGASIKGEFERRLNLVITAVQESPTPIILFIDEAHTLIGAGGQAGSNDAANLLKPALARGELRTIG
ATTWSEYKKYIEKDPALARRFQPVKVNEPNVTQAITILRGLAERYEESHGVYVRDDAIIAAAELSARYISGRQLPDKAID
LLDTACARVKINLKAKPESLERLLHIIAITQRELDCVLRDQQAGINIEENTITLLKEKLSQTHLDAEQLEQEWQTQKELA
EALLTSRIDIAQCNDEEEKHRLICNQQEIHQALSDAQHTHSLVNYETCPSLVAEVVSHWTGIPMSTLQRGQATQVLTIKS
KLKEQIKGQDQAVIALEKAIQATAAGLNNPNSPTGVFLFVGPSGVGKTQTAQAIADLMYGGEQFLTTINMSEFQEKHTVS
RLIGSPPGYVGYGEGGVLTEAVRQRPYSVVLLDEVEKADPEIMNLFYQIFDKGVANDGEGREINFKQTLIIMTSNLASDQ
IEALCNQEEKPTTDALTKAIRPTLNQYFKPALVGRMTVVPFFPLDMESMEALVDIRLKQLTEQLSLQQITLHYDEAIIQH
IAQSCTLTETGARNIDAIINGQLKPAFSSQILLALARKEPLTSISLCIDENGQVFCEFED

Specific function: Required for secretion of hcp1 probably by providing the energy source for its translocation [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=310, Percent_Identity=34.5161290322581, Blast_Score=160, Evalue=6e-39,
Organism=Escherichia coli, GI1788943, Length=707, Percent_Identity=40.8769448373409, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI1787109, Length=413, Percent_Identity=36.0774818401937, Blast_Score=249, Evalue=6e-67,
Organism=Saccharomyces cerevisiae, GI6320464, Length=687, Percent_Identity=38.5735080058224, Blast_Score=489, Evalue=1e-139,
Organism=Saccharomyces cerevisiae, GI6323002, Length=722, Percent_Identity=34.3490304709141, Blast_Score=436, Evalue=1e-122,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR017729
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95080; Mature: 95080

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINVELPQLIKTLDKESHLALEQAAQLCVTRGGNEVLCEDFILAALNNPQSFWNKACQQY
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHC
NVSTDVLIEALQHGRKSTSSESNHPVLSTALIEWLQESYLFSMLEMQLSEVLAANLLLTL
CCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHPNKYGHTPYYRELSVIPVASLKQQVEGLVSCANRDSHSSAEHQNALDAYTTNYTQLA
HHCCCCCCCCCCHHCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHH
KDNKIDPVLCRDSEIRQMIDILARRRKNNPMIVGEAGVGKTALVEGLAIKIAQGEVPDML
CCCCCCCEEECCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHEEEEECCCCHHHH
ENVALLSLDLGLLQAGASIKGEFERRLNLVITAVQESPTPIILFIDEAHTLIGAGGQAGS
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEEECCCCCEEEEEEECCCCEEECCCCCCC
NDAANLLKPALARGELRTIGATTWSEYKKYIEKDPALARRFQPVKVNEPNVTQAITILRG
CCHHHHHHHHHHCCCCCEECCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHH
LAERYEESHGVYVRDDAIIAAAELSARYISGRQLPDKAIDLLDTACARVKINLKAKPESL
HHHHHHHHCCEEEECCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEECCCHHHH
ERLLHIIAITQRELDCVLRDQQAGINIEENTITLLKEKLSQTHLDAEQLEQEWQTQKELA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EALLTSRIDIAQCNDEEEKHRLICNQQEIHQALSDAQHTHSLVNYETCPSLVAEVVSHWT
HHHHHCCCCHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCC
GIPMSTLQRGQATQVLTIKSKLKEQIKGQDQAVIALEKAIQATAAGLNNPNSPTGVFLFV
CCCHHHHCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
GPSGVGKTQTAQAIADLMYGGEQFLTTINMSEFQEKHTVSRLIGSPPGYVGYGEGGVLTE
CCCCCCCHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
AVRQRPYSVVLLDEVEKADPEIMNLFYQIFDKGVANDGEGREINFKQTLIIMTSNLASDQ
HHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCEEEEEEECCCCHHH
IEALCNQEEKPTTDALTKAIRPTLNQYFKPALVGRMTVVPFFPLDMESMEALVDIRLKQL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHH
TEQLSLQQITLHYDEAIIQHIAQSCTLTETGARNIDAIINGQLKPAFSSQILLALARKEP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHCCC
LTSISLCIDENGQVFCEFED
CCEEEEEEECCCCEEEEECC
>Mature Secondary Structure
MINVELPQLIKTLDKESHLALEQAAQLCVTRGGNEVLCEDFILAALNNPQSFWNKACQQY
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHC
NVSTDVLIEALQHGRKSTSSESNHPVLSTALIEWLQESYLFSMLEMQLSEVLAANLLLTL
CCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHPNKYGHTPYYRELSVIPVASLKQQVEGLVSCANRDSHSSAEHQNALDAYTTNYTQLA
HHCCCCCCCCCCHHCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHH
KDNKIDPVLCRDSEIRQMIDILARRRKNNPMIVGEAGVGKTALVEGLAIKIAQGEVPDML
CCCCCCCEEECCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHEEEEECCCCHHHH
ENVALLSLDLGLLQAGASIKGEFERRLNLVITAVQESPTPIILFIDEAHTLIGAGGQAGS
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEEECCCCCEEEEEEECCCCEEECCCCCCC
NDAANLLKPALARGELRTIGATTWSEYKKYIEKDPALARRFQPVKVNEPNVTQAITILRG
CCHHHHHHHHHHCCCCCEECCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHH
LAERYEESHGVYVRDDAIIAAAELSARYISGRQLPDKAIDLLDTACARVKINLKAKPESL
HHHHHHHHCCEEEECCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEECCCHHHH
ERLLHIIAITQRELDCVLRDQQAGINIEENTITLLKEKLSQTHLDAEQLEQEWQTQKELA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EALLTSRIDIAQCNDEEEKHRLICNQQEIHQALSDAQHTHSLVNYETCPSLVAEVVSHWT
HHHHHCCCCHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCC
GIPMSTLQRGQATQVLTIKSKLKEQIKGQDQAVIALEKAIQATAAGLNNPNSPTGVFLFV
CCCHHHHCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
GPSGVGKTQTAQAIADLMYGGEQFLTTINMSEFQEKHTVSRLIGSPPGYVGYGEGGVLTE
CCCCCCCHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
AVRQRPYSVVLLDEVEKADPEIMNLFYQIFDKGVANDGEGREINFKQTLIIMTSNLASDQ
HHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCEEEEEEECCCCHHH
IEALCNQEEKPTTDALTKAIRPTLNQYFKPALVGRMTVVPFFPLDMESMEALVDIRLKQL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHH
TEQLSLQQITLHYDEAIIQHIAQSCTLTETGARNIDAIINGQLKPAFSSQILLALARKEP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHCCC
LTSISLCIDENGQVFCEFED
CCEEEEEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]