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The map label for this gene is hflX [H]

Identifier: 59711578

GI number: 59711578

Start: 1064022

End: 1065380

Strand: Direct

Name: hflX [H]

Synonym: VF_0971

Alternate gene names: 59711578

Gene position: 1064022-1065380 (Clockwise)

Preceding gene: 59711577

Following gene: 59711579

Centisome position: 36.72

GC content: 40.84

Gene sequence:

>1359_bases
ATGAAACTAACTGAAAAACCGCTGCTTAATAACGCCTTACTTATTTCTATTTGTACACCGCAATTTAAAGGTGAGGAAGC
CAAACAATCCTTGGCTGAACTTGCTCGCTTGGTGACAACCTTAGGTTTTAAAGTTGTTGGAACGCAATCTCAAAAGCAAA
CCTCTACGCAAAAGATGAGTGTGCTAGGTGCTGGGAAATTGGCAGAGATCGCACACATCACAGGTAATCAAGGAGAGGGT
ACGGATGCCGATACCGAAGATTTCTTTGATGAAACTGATTTTGATGATATTCCTTCAGAGAACTTACCGTTTGGTTGTGC
TGATGTTGTTGTCTTTGATTGTGATTTAAGTCCATCTCAACTGCGTAATGTTGAGAATCAACTTGGTGTTCAGGTATACG
ATCGTACGGGTATTATCATTGAAATATTCAGCCGCCATGCTCGTACACGTACCGCTCGTCTTCAAGTTGAGATGGCTCGA
CTGAATTATGTCGCCCCAAGATTGAGAGAATCTTCAATCGGTGACAGTGAACGCCAAATGGGTAAAGGTTCAGGTGAGAC
AAGTTTAGAGCTGGACCGTCGTAAAGTTCGTGATCAATTAGCTGAATTACGTCGAGAGTTAGACAGTGTTCAAGATGAAC
TGAAAGGTAGACGAGCTCAGCGTTCTGAACTGTTTTGTGTTGCTTTAGTGGGTTACACCAATGCTGGTAAATCTTCAATG
ATGCGTGCATTAACAGGCAGTGAAGTGCTTGTTGAAAATAAATTATTCGCAACGTTAGATACAACAGTGCGTGCGCTGTA
TCCAGAAACTCAACCTCGAATTCTTGTTTCAGATACCGTAGGGTTCATAAAAAAATTACCCCATGATTTGGTCGCTTCTT
TCCACTCAACGTTAGCAGAAGCGCACGATGCTTCATTATTACTGTATGTAGTAGATGCCTCAGATCCAACCTTTAGAACT
CAACTTGATGTTGTTCATGAGGTACTTGGAGAAGTGGGTGTTGATGGCATTGATAAGTTATTAGTTTTAAATAAATCTGA
TCAACTGACTCCTGAGCAGCAACAAGCATTAATGGAAGAGTTTCCTGATGCGATGATGACATCAACTCGTAATCCACTTG
ATGTAGCCAAATTGCATCAATATATCGTTAACGCTTCAGAGAAAGGGATGATCGAAGAAGAACTCATTGTTCCTTATGAT
GCAAAAGGCATAATGGGAGAGATCCGCTCAAGCATGAGTGTCGTGAATGAAGAATATGATTACGATCATATGAAGTTGAC
GGTACGCTCTAGTGCAATTGATTTAGCAAGATTAAAAAAGCTGATGTCGAATGTATTAAACGAAAATGATAGTGAGTGA

Upstream 100 bases:

>100_bases
TTTAATTTCTATTTACCTATCAAGCTTCTTAATAACAGCGTAGGATTAGACTAACTTTAGCTAAAATCAGGCTTGCACTC
CGGTGCTTTAAGATAAAATC

Downstream 100 bases:

>100_bases
TCACATAGTAAATAGAGTGATACATGCCTATTTAAGTTAAGCCTTAGCAGAAATGTTGAGGCTTTTTCGTATTTATATTG
TCATGAATTTACTGTTTGAT

Product: GTP-binding protein HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKLTEKPLLNNALLISICTPQFKGEEAKQSLAELARLVTTLGFKVVGTQSQKQTSTQKMSVLGAGKLAEIAHITGNQGEG
TDADTEDFFDETDFDDIPSENLPFGCADVVVFDCDLSPSQLRNVENQLGVQVYDRTGIIIEIFSRHARTRTARLQVEMAR
LNYVAPRLRESSIGDSERQMGKGSGETSLELDRRKVRDQLAELRRELDSVQDELKGRRAQRSELFCVALVGYTNAGKSSM
MRALTGSEVLVENKLFATLDTTVRALYPETQPRILVSDTVGFIKKLPHDLVASFHSTLAEAHDASLLLYVVDASDPTFRT
QLDVVHEVLGEVGVDGIDKLLVLNKSDQLTPEQQQALMEEFPDAMMTSTRNPLDVAKLHQYIVNASEKGMIEEELIVPYD
AKGIMGEIRSSMSVVNEEYDYDHMKLTVRSSAIDLARLKKLMSNVLNENDSE

Sequences:

>Translated_452_residues
MKLTEKPLLNNALLISICTPQFKGEEAKQSLAELARLVTTLGFKVVGTQSQKQTSTQKMSVLGAGKLAEIAHITGNQGEG
TDADTEDFFDETDFDDIPSENLPFGCADVVVFDCDLSPSQLRNVENQLGVQVYDRTGIIIEIFSRHARTRTARLQVEMAR
LNYVAPRLRESSIGDSERQMGKGSGETSLELDRRKVRDQLAELRRELDSVQDELKGRRAQRSELFCVALVGYTNAGKSSM
MRALTGSEVLVENKLFATLDTTVRALYPETQPRILVSDTVGFIKKLPHDLVASFHSTLAEAHDASLLLYVVDASDPTFRT
QLDVVHEVLGEVGVDGIDKLLVLNKSDQLTPEQQQALMEEFPDAMMTSTRNPLDVAKLHQYIVNASEKGMIEEELIVPYD
AKGIMGEIRSSMSVVNEEYDYDHMKLTVRSSAIDLARLKKLMSNVLNENDSE
>Mature_452_residues
MKLTEKPLLNNALLISICTPQFKGEEAKQSLAELARLVTTLGFKVVGTQSQKQTSTQKMSVLGAGKLAEIAHITGNQGEG
TDADTEDFFDETDFDDIPSENLPFGCADVVVFDCDLSPSQLRNVENQLGVQVYDRTGIIIEIFSRHARTRTARLQVEMAR
LNYVAPRLRESSIGDSERQMGKGSGETSLELDRRKVRDQLAELRRELDSVQDELKGRRAQRSELFCVALVGYTNAGKSSM
MRALTGSEVLVENKLFATLDTTVRALYPETQPRILVSDTVGFIKKLPHDLVASFHSTLAEAHDASLLLYVVDASDPTFRT
QLDVVHEVLGEVGVDGIDKLLVLNKSDQLTPEQQQALMEEFPDAMMTSTRNPLDVAKLHQYIVNASEKGMIEEELIVPYD
AKGIMGEIRSSMSVVNEEYDYDHMKLTVRSSAIDLARLKKLMSNVLNENDSE

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=137, Percent_Identity=38.6861313868613, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310124269, Length=137, Percent_Identity=38.6861313868613, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310124267, Length=137, Percent_Identity=38.6861313868613, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310124171, Length=137, Percent_Identity=38.6861313868613, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310124169, Length=137, Percent_Identity=38.6861313868613, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310133118, Length=137, Percent_Identity=38.6861313868613, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1790615, Length=439, Percent_Identity=32.3462414578588, Blast_Score=193, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17561038, Length=229, Percent_Identity=33.6244541484716, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24650079, Length=252, Percent_Identity=34.9206349206349, Blast_Score=108, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50234; Mature: 50234

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTEKPLLNNALLISICTPQFKGEEAKQSLAELARLVTTLGFKVVGTQSQKQTSTQKMS
CCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHH
VLGAGKLAEIAHITGNQGEGTDADTEDFFDETDFDDIPSENLPFGCADVVVFDCDLSPSQ
HHCCCCHHHHHEECCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHH
LRNVENQLGVQVYDRTGIIIEIFSRHARTRTARLQVEMARLNYVAPRLRESSIGDSERQM
HHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GKGSGETSLELDRRKVRDQLAELRRELDSVQDELKGRRAQRSELFCVALVGYTNAGKSSM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEEEECCCCCHHHH
MRALTGSEVLVENKLFATLDTTVRALYPETQPRILVSDTVGFIKKLPHDLVASFHSTLAE
HHHHCCCCEEECCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHH
AHDASLLLYVVDASDPTFRTQLDVVHEVLGEVGVDGIDKLLVLNKSDQLTPEQQQALMEE
HCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHH
FPDAMMTSTRNPLDVAKLHQYIVNASEKGMIEEELIVPYDAKGIMGEIRSSMSVVNEEYD
CCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHEECCCCCHHHHHHHHHHHHHHHHCCC
YDHMKLTVRSSAIDLARLKKLMSNVLNENDSE
CCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKLTEKPLLNNALLISICTPQFKGEEAKQSLAELARLVTTLGFKVVGTQSQKQTSTQKMS
CCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHH
VLGAGKLAEIAHITGNQGEGTDADTEDFFDETDFDDIPSENLPFGCADVVVFDCDLSPSQ
HHCCCCHHHHHEECCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHH
LRNVENQLGVQVYDRTGIIIEIFSRHARTRTARLQVEMARLNYVAPRLRESSIGDSERQM
HHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GKGSGETSLELDRRKVRDQLAELRRELDSVQDELKGRRAQRSELFCVALVGYTNAGKSSM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEEEECCCCCHHHH
MRALTGSEVLVENKLFATLDTTVRALYPETQPRILVSDTVGFIKKLPHDLVASFHSTLAE
HHHHCCCCEEECCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHH
AHDASLLLYVVDASDPTFRTQLDVVHEVLGEVGVDGIDKLLVLNKSDQLTPEQQQALMEE
HCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHH
FPDAMMTSTRNPLDVAKLHQYIVNASEKGMIEEELIVPYDAKGIMGEIRSSMSVVNEEYD
CCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHEECCCCCHHHHHHHHHHHHHHHHCCC
YDHMKLTVRSSAIDLARLKKLMSNVLNENDSE
CCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]