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The map label for this gene is ruvB [H]

Identifier: 59711559

GI number: 59711559

Start: 1047581

End: 1048594

Strand: Direct

Name: ruvB [H]

Synonym: VF_0952

Alternate gene names: 59711559

Gene position: 1047581-1048594 (Clockwise)

Preceding gene: 59711558

Following gene: 59711560

Centisome position: 36.15

GC content: 40.14

Gene sequence:

>1014_bases
ATGATTGAAGCTGATCGTTTAATTGCAGCAGATAACCCAACTTTTCGTGAAGAGGATGTGATTGATAGAGCCATCCGTCC
TAAAAAGCTAGATGATTACCAAGGCCAAGACCATGTTCGTAGCCAAATGGAGATTTTCATTAAAGCTGCACAAATGCGTG
AAGAAGCACTGGATCACTTACTCATTTTTGGCCCTCCAGGTTTAGGTAAGACAACATTAGCCAATATTGTAGCTAATGAG
ATGGGCGTAAATATAAGAACGACATCAGGACCGGTTCTTGAAAAAGCAGGGGACTTAGCTGCATTACTAACTAATTTAGA
AGAAAACGACATTTTATTTATTGATGAAATTCATCGTTTAAGTCCTATGGTTGAAGAAGTGCTTTATCCTGCGATGGAAG
ACTATCAACTTGATATCATGATAGGTGAAGGTCCTGCAGCACGTTCAATAAAGATAGATTTACCTCCGTTTACTTTAATT
GGTGCAACGACAAGGGCTGGATCATTAACATCTCCGCTTCGTGATCGTTTTGGTATTGTCCAACGTTTAGAATATTACAA
GGTAGAAGATCTTCAGCATATTGTTCAACGCAGTGCAGATTGTTTGAATTTATCCATGGAATCTGAAGGTGCATTAGAAG
TTGCTCGTCGTGCACGCGGTACTCCACGTATTGCCAACCGTTTATTACGTCGTGTTCGTGACTATGCTGAAGTCATGAGT
GACGGGAACATTTCATCTGAGATTGCTGATAAAGCGCTTAATATGCTCGATGTGGACGTTCGTGGTTTTGATTACATGGA
CAGAAAGTTATTGTTAGCGATTATGGAAAAGTTTGATGGTGGGCCTGTTGGTTTAGATAATATTGCAGCAGCCATTGGTG
AAGAGCGTGATACCATTGAAGATGTTATTGAACCTTATCTCATTCAGCAAGGTTATCTGCAAAGAACGCCTAGAGGACGA
ATTGTATCCGATAGAGCGTATCTACATTTTGGAATTGATAAGCCTGATAAATAG

Upstream 100 bases:

>100_bases
TGTTTCTCAAATTGCTAAGCCGGACATGACCAGCGAAGTATTGATCCGTGAATCATTAAAGTCGATGATTTAATCATCTT
CTAATTGTTGAGTACTTATT

Downstream 100 bases:

>100_bases
ATTTCGTTACAGTATTAATATATTTACACAGTCTATTAATATTTCAAGCTGAGTTAATTGAAAGCGAGTGATCAAAATCA
CTCGTTTTTTCGTATATGGA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MIEADRLIAADNPTFREEDVIDRAIRPKKLDDYQGQDHVRSQMEIFIKAAQMREEALDHLLIFGPPGLGKTTLANIVANE
MGVNIRTTSGPVLEKAGDLAALLTNLEENDILFIDEIHRLSPMVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLI
GATTRAGSLTSPLRDRFGIVQRLEYYKVEDLQHIVQRSADCLNLSMESEGALEVARRARGTPRIANRLLRRVRDYAEVMS
DGNISSEIADKALNMLDVDVRGFDYMDRKLLLAIMEKFDGGPVGLDNIAAAIGEERDTIEDVIEPYLIQQGYLQRTPRGR
IVSDRAYLHFGIDKPDK

Sequences:

>Translated_337_residues
MIEADRLIAADNPTFREEDVIDRAIRPKKLDDYQGQDHVRSQMEIFIKAAQMREEALDHLLIFGPPGLGKTTLANIVANE
MGVNIRTTSGPVLEKAGDLAALLTNLEENDILFIDEIHRLSPMVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLI
GATTRAGSLTSPLRDRFGIVQRLEYYKVEDLQHIVQRSADCLNLSMESEGALEVARRARGTPRIANRLLRRVRDYAEVMS
DGNISSEIADKALNMLDVDVRGFDYMDRKLLLAIMEKFDGGPVGLDNIAAAIGEERDTIEDVIEPYLIQQGYLQRTPRGR
IVSDRAYLHFGIDKPDK
>Mature_337_residues
MIEADRLIAADNPTFREEDVIDRAIRPKKLDDYQGQDHVRSQMEIFIKAAQMREEALDHLLIFGPPGLGKTTLANIVANE
MGVNIRTTSGPVLEKAGDLAALLTNLEENDILFIDEIHRLSPMVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLI
GATTRAGSLTSPLRDRFGIVQRLEYYKVEDLQHIVQRSADCLNLSMESEGALEVARRARGTPRIANRLLRRVRDYAEVMS
DGNISSEIADKALNMLDVDVRGFDYMDRKLLLAIMEKFDGGPVGLDNIAAAIGEERDTIEDVIEPYLIQQGYLQRTPRGR
IVSDRAYLHFGIDKPDK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=336, Percent_Identity=80.3571428571429, Blast_Score=542, Evalue=1e-156,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37822; Mature: 37822

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEADRLIAADNPTFREEDVIDRAIRPKKLDDYQGQDHVRSQMEIFIKAAQMREEALDHL
CCCCCCEEECCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEE
LIFGPPGLGKTTLANIVANEMGVNIRTTSGPVLEKAGDLAALLTNLEENDILFIDEIHRL
EEECCCCCCHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHH
SPMVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIV
HHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHHHH
QRLEYYKVEDLQHIVQRSADCLNLSMESEGALEVARRARGTPRIANRLLRRVRDYAEVMS
HHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
DGNISSEIADKALNMLDVDVRGFDYMDRKLLLAIMEKFDGGPVGLDNIAAAIGEERDTIE
CCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHH
DVIEPYLIQQGYLQRTPRGRIVSDRAYLHFGIDKPDK
HHHHHHHHHHHHHHCCCCCCEEECCEEEEECCCCCCC
>Mature Secondary Structure
MIEADRLIAADNPTFREEDVIDRAIRPKKLDDYQGQDHVRSQMEIFIKAAQMREEALDHL
CCCCCCEEECCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEE
LIFGPPGLGKTTLANIVANEMGVNIRTTSGPVLEKAGDLAALLTNLEENDILFIDEIHRL
EEECCCCCCHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHH
SPMVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIV
HHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHHHH
QRLEYYKVEDLQHIVQRSADCLNLSMESEGALEVARRARGTPRIANRLLRRVRDYAEVMS
HHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
DGNISSEIADKALNMLDVDVRGFDYMDRKLLLAIMEKFDGGPVGLDNIAAAIGEERDTIE
CCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHH
DVIEPYLIQQGYLQRTPRGRIVSDRAYLHFGIDKPDK
HHHHHHHHHHHHHHCCCCCCEEECCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA