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The map label for this gene is ruvC [H]

Identifier: 59711557

GI number: 59711557

Start: 1046303

End: 1046824

Strand: Direct

Name: ruvC [H]

Synonym: VF_0950

Alternate gene names: 59711557

Gene position: 1046303-1046824 (Clockwise)

Preceding gene: 59711556

Following gene: 59711558

Centisome position: 36.11

GC content: 43.68

Gene sequence:

>522_bases
ATGTCTATCATTTTAGGGATTGATCCCGGCTCACGTATTACTGGATATGGTGTTATTCGCCAGAATGGCCGTCATCTGCA
ATATCTTGGCAGCGGTTGTATTCGTATGTCTGAAAAAGAACTACCTGGTCGATTAAAGCAAATTTATGCGGGGGTTTCTG
AAATTATCACGCAATTCCAACCTGATGTGTTTGCGATTGAACAAGTATTTATGTCAAAAAATGCTGACTCAGCATTAAAG
CTTGGTCAAGCAAGAGGCAGTGCAATTGTCGCCGCAGTGAATGCAGACTTACCCGTTTATGAATATGCAGCTCGTTTAAT
TAAGCAAGCAGTAACAGGGACGGGGGGGGCTGATAAATCTCAAGTTCAACATATGGTCATGAGTATGCTGAAATTACCGG
CTAAGCCACAAGCCGATGCGGCTGATGCATTAGGCGCAGCTATTTGTCATGCAAATACCAATAAAACATTAATTGCGCTA
GCCGGAAAAGCAACGGGTGCACGTCGTGGGCGTTATAGATAA

Upstream 100 bases:

>100_bases
ATCTATACTATGTAAAGTGAGACAGCTCTTTATTACTAATACCTTGAGTTTATAGTGGTATCTAGCTAATATACATGTAT
AAATAATCAGTGGTTTTTAT

Downstream 100 bases:

>100_bases
GGAACACCAGTGTCGCTTGTTATAAATTCTCATTTCTTTTACTGGATATCTATCCAGTTCTTTATTACTATCTTAACTTA
TTATTTATTTTAAAGAGTAT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MSIILGIDPGSRITGYGVIRQNGRHLQYLGSGCIRMSEKELPGRLKQIYAGVSEIITQFQPDVFAIEQVFMSKNADSALK
LGQARGSAIVAAVNADLPVYEYAARLIKQAVTGTGGADKSQVQHMVMSMLKLPAKPQADAADALGAAICHANTNKTLIAL
AGKATGARRGRYR

Sequences:

>Translated_173_residues
MSIILGIDPGSRITGYGVIRQNGRHLQYLGSGCIRMSEKELPGRLKQIYAGVSEIITQFQPDVFAIEQVFMSKNADSALK
LGQARGSAIVAAVNADLPVYEYAARLIKQAVTGTGGADKSQVQHMVMSMLKLPAKPQADAADALGAAICHANTNKTLIAL
AGKATGARRGRYR
>Mature_172_residues
SIILGIDPGSRITGYGVIRQNGRHLQYLGSGCIRMSEKELPGRLKQIYAGVSEIITQFQPDVFAIEQVFMSKNADSALKL
GQARGSAIVAAVNADLPVYEYAARLIKQAVTGTGGADKSQVQHMVMSMLKLPAKPQADAADALGAAICHANTNKTLIALA
GKATGARRGRYR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=173, Percent_Identity=69.9421965317919, Blast_Score=229, Evalue=8e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 18400; Mature: 18268

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIILGIDPGSRITGYGVIRQNGRHLQYLGSGCIRMSEKELPGRLKQIYAGVSEIITQFQ
CEEEEECCCCCCEEEEEEEECCCCEEEECCCCHHCCCCHHCCHHHHHHHHHHHHHHHHHC
PDVFAIEQVFMSKNADSALKLGQARGSAIVAAVNADLPVYEYAARLIKQAVTGTGGADKS
CCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHH
QVQHMVMSMLKLPAKPQADAADALGAAICHANTNKTLIALAGKATGARRGRYR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SIILGIDPGSRITGYGVIRQNGRHLQYLGSGCIRMSEKELPGRLKQIYAGVSEIITQFQ
EEEEECCCCCCEEEEEEEECCCCEEEECCCCHHCCCCHHCCHHHHHHHHHHHHHHHHHC
PDVFAIEQVFMSKNADSALKLGQARGSAIVAAVNADLPVYEYAARLIKQAVTGTGGADKS
CCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHH
QVQHMVMSMLKLPAKPQADAADALGAAICHANTNKTLIALAGKATGARRGRYR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA