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The map label for this gene is cmoB [H]

Identifier: 59711554

GI number: 59711554

Start: 1042249

End: 1043223

Strand: Reverse

Name: cmoB [H]

Synonym: VF_0947

Alternate gene names: 59711554

Gene position: 1043223-1042249 (Counterclockwise)

Preceding gene: 59711555

Following gene: 59711553

Centisome position: 36.0

GC content: 39.69

Gene sequence:

>975_bases
ATGTTTAATTTTGCTAATTTTTATCAACTAATTGCCCAAGATACCGTTCTTCAACCTTGGTTAAATACATTGCCTCAACA
ACTAACAGATTGGCAGAATGCAGAACATGGTGATATTGAGCGTTGGATAAAAGCGTTGAAAAAAATCCCAGAGGGATGCG
CTGATAATATCGACTTAAAATCATCAGTAACGCTATCAAATAACACACCATTAATTGATGGCGAACGCAAAAAATTAGAA
AACTTATTACAAACGTTCCATCCGTGGCGCAAAGGCCCATTTACGGTTCATGACATTCATATTGATACTGAGTGGCGATC
AGATTGGAAGTGGGATCGTTTGTTACCTCACATTACACCACTAAAAAATCGTTCAGTTTTAGATGTTGGTTGCGGTAACG
GATATCATATGTGGCGCATGCTTGGTGAAGATGCACGTTTGTGTGTGGGTATTGACCCTTCACATTTGTTTTTAATCCAG
TTTGAAGCAATTCGTAAACTAATGGGGAATGACCAACGTGCTCACTTATTGCCATTAGGAATTGAGCAGCTTCCTGAATT
GAATGCGTTTGACACCGTATTTAGCATGGGTGTGTTGTATCACCGTCGTTCTCCTCTAGATCATCTAATTCAACTAAAAA
ATCAATTAGTTGCTGGTGGAGAGTTGGTGCTAGAAACATTAGTTATTGATGGCGACGAAAACGCAGTATTAATGCCAGTT
GATCGCTACGCTCAAATGCGCAATGTATACTTCTTCCCATCAGCTCGAGCACTAAAAGTATGGTTAGAGAGCGTGGGATT
TGTCGATGTAAAAATAGTAGATGAATGTGTGACAACAACAGGCGAGCAACGCTCTACTGAATGGATGAAACACAACTCTC
TACCTGAATACTTAGACCCAAATGATTCAACAAAAACCATTGAAGGTCATCCGGCACCAAAACGTGCGATTTTAATAGCA
AAGAAACCTGACTAA

Upstream 100 bases:

>100_bases
CTTTAAAAGCTCTGAAGTATGGTTCCAATGTTTTAACTTCGGTTCAATGTTTGCCATCAAATAACCCTGTTTTGTTATCA
CCAACTATATAAAGATATTT

Downstream 100 bases:

>100_bases
ACTTTAACATTTGGGGGCTATTCGCTCCCATTTATTATCGTTATTATGCACATGTTAATTTAACTCAACGGAACATAAAA
TGATCCAACGAATTCTACCA

Product: S-adenosyl-L-methionine-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MFNFANFYQLIAQDTVLQPWLNTLPQQLTDWQNAEHGDIERWIKALKKIPEGCADNIDLKSSVTLSNNTPLIDGERKKLE
NLLQTFHPWRKGPFTVHDIHIDTEWRSDWKWDRLLPHITPLKNRSVLDVGCGNGYHMWRMLGEDARLCVGIDPSHLFLIQ
FEAIRKLMGNDQRAHLLPLGIEQLPELNAFDTVFSMGVLYHRRSPLDHLIQLKNQLVAGGELVLETLVIDGDENAVLMPV
DRYAQMRNVYFFPSARALKVWLESVGFVDVKIVDECVTTTGEQRSTEWMKHNSLPEYLDPNDSTKTIEGHPAPKRAILIA
KKPD

Sequences:

>Translated_324_residues
MFNFANFYQLIAQDTVLQPWLNTLPQQLTDWQNAEHGDIERWIKALKKIPEGCADNIDLKSSVTLSNNTPLIDGERKKLE
NLLQTFHPWRKGPFTVHDIHIDTEWRSDWKWDRLLPHITPLKNRSVLDVGCGNGYHMWRMLGEDARLCVGIDPSHLFLIQ
FEAIRKLMGNDQRAHLLPLGIEQLPELNAFDTVFSMGVLYHRRSPLDHLIQLKNQLVAGGELVLETLVIDGDENAVLMPV
DRYAQMRNVYFFPSARALKVWLESVGFVDVKIVDECVTTTGEQRSTEWMKHNSLPEYLDPNDSTKTIEGHPAPKRAILIA
KKPD
>Mature_324_residues
MFNFANFYQLIAQDTVLQPWLNTLPQQLTDWQNAEHGDIERWIKALKKIPEGCADNIDLKSSVTLSNNTPLIDGERKKLE
NLLQTFHPWRKGPFTVHDIHIDTEWRSDWKWDRLLPHITPLKNRSVLDVGCGNGYHMWRMLGEDARLCVGIDPSHLFLIQ
FEAIRKLMGNDQRAHLLPLGIEQLPELNAFDTVFSMGVLYHRRSPLDHLIQLKNQLVAGGELVLETLVIDGDENAVLMPV
DRYAQMRNVYFFPSARALKVWLESVGFVDVKIVDECVTTTGEQRSTEWMKHNSLPEYLDPNDSTKTIEGHPAPKRAILIA
KKPD

Specific function: Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoB family [H]

Homologues:

Organism=Escherichia coli, GI1788178, Length=324, Percent_Identity=64.5061728395062, Blast_Score=436, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010017 [H]

Pfam domain/function: PF08003 Methyltransf_9 [H]

EC number: NA

Molecular weight: Translated: 37235; Mature: 37235

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNFANFYQLIAQDTVLQPWLNTLPQQLTDWQNAEHGDIERWIKALKKIPEGCADNIDLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
SSVTLSNNTPLIDGERKKLENLLQTFHPWRKGPFTVHDIHIDTEWRSDWKWDRLLPHITP
CEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHHCCCCCC
LKNRSVLDVGCGNGYHMWRMLGEDARLCVGIDPSHLFLIQFEAIRKLMGNDQRAHLLPLG
CCCCCEEEECCCCCHHHHHHHCCCCCEEEECCCCEEEEEEHHHHHHHHCCCCCEEEEECC
IEQLPELNAFDTVFSMGVLYHRRSPLDHLIQLKNQLVAGGELVLETLVIDGDENAVLMPV
HHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHEEEEEEEEECCCCEEEEEH
DRYAQMRNVYFFPSARALKVWLESVGFVDVKIVDECVTTTGEQRSTEWMKHNSLPEYLDP
HHHHHHCCEEECCCHHHHHHHHHHCCCEEEEEHHHHHHCCCCHHHHHHHHHCCCCCCCCC
NDSTKTIEGHPAPKRAILIAKKPD
CCCCCEECCCCCCCEEEEEEECCC
>Mature Secondary Structure
MFNFANFYQLIAQDTVLQPWLNTLPQQLTDWQNAEHGDIERWIKALKKIPEGCADNIDLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
SSVTLSNNTPLIDGERKKLENLLQTFHPWRKGPFTVHDIHIDTEWRSDWKWDRLLPHITP
CEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHHCCCCCC
LKNRSVLDVGCGNGYHMWRMLGEDARLCVGIDPSHLFLIQFEAIRKLMGNDQRAHLLPLG
CCCCCEEEECCCCCHHHHHHHCCCCCEEEECCCCEEEEEEHHHHHHHHCCCCCEEEEECC
IEQLPELNAFDTVFSMGVLYHRRSPLDHLIQLKNQLVAGGELVLETLVIDGDENAVLMPV
HHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHEEEEEEEEECCCCEEEEEH
DRYAQMRNVYFFPSARALKVWLESVGFVDVKIVDECVTTTGEQRSTEWMKHNSLPEYLDP
HHHHHHCCEEECCCHHHHHHHHHHCCCEEEEEHHHHHHCCCCHHHHHHHHHCCCCCCCCC
NDSTKTIEGHPAPKRAILIAKKPD
CCCCCEECCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA