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The map label for this gene is fabF [H]

Identifier: 59711464

GI number: 59711464

Start: 943261

End: 944448

Strand: Direct

Name: fabF [H]

Synonym: VF_0857

Alternate gene names: 59711464

Gene position: 943261-944448 (Clockwise)

Preceding gene: 59711463

Following gene: 59711465

Centisome position: 32.55

GC content: 41.67

Gene sequence:

>1188_bases
ATGAGTGACTTTCCTTTATATATACATGCGTGTGGCTCACATTCAGCCATGGGTAAAGAGGTTGATGAAATCCATCAAGT
ATTGAGTGGAAATAAAGCGCCATCAATGCATAAAGAGACAGGTTGGCTCAATAATGGAAAGGCAACAGTCGTTGGTAAAG
CATTAGGTGAGTTACCTTTAGTTCCTGAGCATTTGGCTCATTGGGATACCAGAAATAATCAGCTTGTTTTGTCCGCTTTA
CAGCAAATCGAACCTCAAATTAACGCCGCAAAAGAGAAATACGGTTCAGATCGTATTGCTGTTATTGTTGGTACGAGTAC
TTCAGGGATCTCGGATGGTGAAGTCGCTTTAAAAGAGAAGATGGAGCAAGGGGCTTTTCCTGCTGGTTATAGCTATAAAC
AACAAGAGTTAGGAAACCCCGCGGATTTTATTGCTCAATATCTTGATATCAATGGACCAACGTATGCGATCTCAACCGCT
TGTTCCTCAAGTGGTCGTGTTTTCTTATCAGCAAAGCGTTTATTAAAAGCAGGGTTTGTTGATGCGGTTATCGTTGGCGG
TACTGACAGTTTATGCCGTTTAACATTAAATGGTTTCAACAGCCTAGAAGCACTATCAAATGAGTATTGTCTGCCGTTTA
GTCCCAATCGAAAAGGGATAAACATTGGTGAAGCTAGCGCATATATGTTGTTAAGTGCAGAGCAAAAAGATTCTGATGAT
CCTATTGCTTTATTAGGAGCTGGAGATAGCTCAGATGCTCACCATATATCGGCCCCGCACCCTGAAGGAAAAGGGGCAAT
TGAAGCGATGAATAAAGCGCTAACAGATGCTGGTTTGGAACCTAAAGACATTGGTTATATTAATGCGCATGGAACCGCCA
CACCGCTGAATGATGCCATGGAATCTAAAGCCGTTCATGCGGTGTTTGGTCATTCAGTACCGGTGAGCTCAACAAAACCA
TTCACTGGGCACACATTAGGTGCCGCAGGTATCATTGAAGCAAGCATTTGTTGGCATATTTTAAAGTATAATTTACCGCT
ACCTAAGCAGATTAATGACGGACAGCAAGATGATGCACTGGCTGATATTCAGCTTGTGGTCGATCAACCACTAAGAAAAA
AAGCCGTTATTAGTAATTCATTTGCCTTTGGCGGTAATAACATCAGTTTAATTTTTGGATGTATTTGA

Upstream 100 bases:

>100_bases
GTGAAATTGTGTTAACCAGTCCAGATTTTGGTTATGTCATAAAAATTAAAACGTTCTCGCATTCAAATACAACAACTCAA
AATAATAACGGATAAATTAA

Downstream 100 bases:

>100_bases
TGAGTAGTATTCCTCCTTTAATCGACCTTTTACCCCATGATACACCTTTAGCTCTTGTTGATGAGTTGATTGAGGTAAAT
GACTTATCGGTTCATTGTCA

Product: 3-oxoacyl-(acyl carrier protein) synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSDFPLYIHACGSHSAMGKEVDEIHQVLSGNKAPSMHKETGWLNNGKATVVGKALGELPLVPEHLAHWDTRNNQLVLSAL
QQIEPQINAAKEKYGSDRIAVIVGTSTSGISDGEVALKEKMEQGAFPAGYSYKQQELGNPADFIAQYLDINGPTYAISTA
CSSSGRVFLSAKRLLKAGFVDAVIVGGTDSLCRLTLNGFNSLEALSNEYCLPFSPNRKGINIGEASAYMLLSAEQKDSDD
PIALLGAGDSSDAHHISAPHPEGKGAIEAMNKALTDAGLEPKDIGYINAHGTATPLNDAMESKAVHAVFGHSVPVSSTKP
FTGHTLGAAGIIEASICWHILKYNLPLPKQINDGQQDDALADIQLVVDQPLRKKAVISNSFAFGGNNISLIFGCI

Sequences:

>Translated_395_residues
MSDFPLYIHACGSHSAMGKEVDEIHQVLSGNKAPSMHKETGWLNNGKATVVGKALGELPLVPEHLAHWDTRNNQLVLSAL
QQIEPQINAAKEKYGSDRIAVIVGTSTSGISDGEVALKEKMEQGAFPAGYSYKQQELGNPADFIAQYLDINGPTYAISTA
CSSSGRVFLSAKRLLKAGFVDAVIVGGTDSLCRLTLNGFNSLEALSNEYCLPFSPNRKGINIGEASAYMLLSAEQKDSDD
PIALLGAGDSSDAHHISAPHPEGKGAIEAMNKALTDAGLEPKDIGYINAHGTATPLNDAMESKAVHAVFGHSVPVSSTKP
FTGHTLGAAGIIEASICWHILKYNLPLPKQINDGQQDDALADIQLVVDQPLRKKAVISNSFAFGGNNISLIFGCI
>Mature_394_residues
SDFPLYIHACGSHSAMGKEVDEIHQVLSGNKAPSMHKETGWLNNGKATVVGKALGELPLVPEHLAHWDTRNNQLVLSALQ
QIEPQINAAKEKYGSDRIAVIVGTSTSGISDGEVALKEKMEQGAFPAGYSYKQQELGNPADFIAQYLDINGPTYAISTAC
SSSGRVFLSAKRLLKAGFVDAVIVGGTDSLCRLTLNGFNSLEALSNEYCLPFSPNRKGINIGEASAYMLLSAEQKDSDDP
IALLGAGDSSDAHHISAPHPEGKGAIEAMNKALTDAGLEPKDIGYINAHGTATPLNDAMESKAVHAVFGHSVPVSSTKPF
TGHTLGAAGIIEASICWHILKYNLPLPKQINDGQQDDALADIQLVVDQPLRKKAVISNSFAFGGNNISLIFGCI

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=262, Percent_Identity=39.6946564885496, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI223972627, Length=150, Percent_Identity=44, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI41872631, Length=276, Percent_Identity=30.4347826086957, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1787337, Length=260, Percent_Identity=36.9230769230769, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788663, Length=262, Percent_Identity=32.0610687022901, Blast_Score=115, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71983541, Length=341, Percent_Identity=31.6715542521994, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71983535, Length=259, Percent_Identity=33.5907335907336, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI212642053, Length=271, Percent_Identity=28.4132841328413, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17550940, Length=258, Percent_Identity=24.031007751938, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320904, Length=266, Percent_Identity=32.7067669172932, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24644341, Length=268, Percent_Identity=36.5671641791045, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI221330659, Length=271, Percent_Identity=27.6752767527675, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19920632, Length=271, Percent_Identity=27.6752767527675, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581345, Length=272, Percent_Identity=26.1029411764706, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 41902; Mature: 41771

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFPLYIHACGSHSAMGKEVDEIHQVLSGNKAPSMHKETGWLNNGKATVVGKALGELPL
CCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHCCCCCCCCEEEEEHHHCCCCC
VPEHLAHWDTRNNQLVLSALQQIEPQINAAKEKYGSDRIAVIVGTSTSGISDGEVALKEK
CHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHH
MEQGAFPAGYSYKQQELGNPADFIAQYLDINGPTYAISTACSSSGRVFLSAKRLLKAGFV
HHHCCCCCCCCCCHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEHHHHHHCCCE
DAVIVGGTDSLCRLTLNGFNSLEALSNEYCLPFSPNRKGINIGEASAYMLLSAEQKDSDD
EEEEECCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCC
PIALLGAGDSSDAHHISAPHPEGKGAIEAMNKALTDAGLEPKDIGYINAHGTATPLNDAM
CEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHH
ESKAVHAVFGHSVPVSSTKPFTGHTLGAAGIIEASICWHILKYNLPLPKQINDGQQDDAL
HHHHEEEHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
ADIQLVVDQPLRKKAVISNSFAFGGNNISLIFGCI
HHHHHHHCCCHHHHHHHCCCEEECCCCEEEEEECC
>Mature Secondary Structure 
SDFPLYIHACGSHSAMGKEVDEIHQVLSGNKAPSMHKETGWLNNGKATVVGKALGELPL
CCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHCCCCCCCCEEEEEHHHCCCCC
VPEHLAHWDTRNNQLVLSALQQIEPQINAAKEKYGSDRIAVIVGTSTSGISDGEVALKEK
CHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHH
MEQGAFPAGYSYKQQELGNPADFIAQYLDINGPTYAISTACSSSGRVFLSAKRLLKAGFV
HHHCCCCCCCCCCHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEHHHHHHCCCE
DAVIVGGTDSLCRLTLNGFNSLEALSNEYCLPFSPNRKGINIGEASAYMLLSAEQKDSDD
EEEEECCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCC
PIALLGAGDSSDAHHISAPHPEGKGAIEAMNKALTDAGLEPKDIGYINAHGTATPLNDAM
CEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHH
ESKAVHAVFGHSVPVSSTKPFTGHTLGAAGIIEASICWHILKYNLPLPKQINDGQQDDAL
HHHHEEEHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
ADIQLVVDQPLRKKAVISNSFAFGGNNISLIFGCI
HHHHHHHCCCHHHHHHHCCCEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA