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The map label for this gene is sucC [H]

Identifier: 59711432

GI number: 59711432

Start: 906218

End: 907384

Strand: Direct

Name: sucC [H]

Synonym: VF_0825

Alternate gene names: 59711432

Gene position: 906218-907384 (Clockwise)

Preceding gene: 59711431

Following gene: 59711433

Centisome position: 31.28

GC content: 43.19

Gene sequence:

>1167_bases
ATGAACTTACATGAATATCAAGCAAAGCAGCTCTTTGCAGAATTTGGCCTTCCTGTACCCGAGGGTTATGCTTGCGATAC
ACCTCAAGAAGCTTTTGAAGCTGCAGGCCGTATTAGCACGGCGAAAAAAGTAGTTAAGTGTCAAGTACACGCTGGTGGCC
GTGGTAAAGCGGGCGGTGTTGAACTGCATGACACGAAAGAAGGCGTTAAAGAATTTGCACAAAAATGGCTAGGTAAAAAT
CTAGTTACTTTCCAAACGGATGCCAACGGCCAACCTGTATCAAAAATTTTAGTTGAAGAAGCATCAAATATTGCGAATGA
ATTGTACTTAGGTGCAGTTGTCGATCGTGCATCACAGCGTATTGTATTTATGGCATCGACTGAAGGTGGCGTTGATATTG
AAAAAATTGCTGAAGAAACACCAGAACTGATACATAAAGCGGCGATCGATCCTCTTGTTGGCCCTCAAGCATACCAAGGT
CGTGAACTGGCATTCAAATTGGGTTTAGAAGGCGATCAAATTAAGCAATTTGTTAAAATCTTCATGGGCCTAGGTAACAT
GTTTGCTCAGTACGATTTAGCACTTCTTGAAATCAACCCATTAGTAGTTACTGCTGAAGGTAGCCTTCTATGTCTTGACG
GCAAAATCAACATTGATTCAAATGCGATGTACCGTCAACCTAAGCTTCGTGAAATGCACGATCCATCTCAAGAAGACGAG
CGTGAAGCGCATGCTGCTCAGTGGGAATTAAACTACGTAGCACTTGATGGCAGCATTGGCTGTATGGTTAATGGTGCGGG
TCTTGCGATGGGTACGATGGATATCGTAAATCTACACGGTGGCCAACCAGCTAACTTCCTTGATGTAGGTGGTGGTGCAA
CAAAAGAGCGTGTAACTGAAGCGTTCAAAATTATTTTATCAGACAGTAATGTTAAAGCGGTTCTAGTAAACATCTTTGGT
GGTATTGTTCGTTGTGATCTAATTGCAGATGGCATCATTGGTGCTGTTGAAGAAGTGGGTGTTGAAGTTCCTGTTGTTGT
TCGCCTTGAAGGTAACAACGCACCACTAGGTTCACAAAAACTGGCTGAAAGTGGCCTAAATATCATTGCGGCTACTTCAT
TAACTGAAGCGGCTGAAAAAGTTGTTGCTGCAGCGGAGGGCAAATAA

Upstream 100 bases:

>100_bases
TCAACTTCATTATTGGATAAAAAATAGAAAGAGACCTTAGAGCCTCTTAGGACATTAAAAATTCCCATAAAAGGGAATAA
CATAAAATGGATAGAACATA

Downstream 100 bases:

>100_bases
TGTCTGTACTAATTAATAAAGATACAAAAGTTATCTGCCAAGGTTTTACTGGTGGTCAAGGTACGTTCCACTCAGAGCAA
GCCATTGATTACGGAACACA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKEFAQKWLGKN
LVTFQTDANGQPVSKILVEEASNIANELYLGAVVDRASQRIVFMASTEGGVDIEKIAEETPELIHKAAIDPLVGPQAYQG
RELAFKLGLEGDQIKQFVKIFMGLGNMFAQYDLALLEINPLVVTAEGSLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
REAHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVNLHGGQPANFLDVGGGATKERVTEAFKIILSDSNVKAVLVNIFG
GIVRCDLIADGIIGAVEEVGVEVPVVVRLEGNNAPLGSQKLAESGLNIIAATSLTEAAEKVVAAAEGK

Sequences:

>Translated_388_residues
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKEFAQKWLGKN
LVTFQTDANGQPVSKILVEEASNIANELYLGAVVDRASQRIVFMASTEGGVDIEKIAEETPELIHKAAIDPLVGPQAYQG
RELAFKLGLEGDQIKQFVKIFMGLGNMFAQYDLALLEINPLVVTAEGSLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
REAHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVNLHGGQPANFLDVGGGATKERVTEAFKIILSDSNVKAVLVNIFG
GIVRCDLIADGIIGAVEEVGVEVPVVVRLEGNNAPLGSQKLAESGLNIIAATSLTEAAEKVVAAAEGK
>Mature_388_residues
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKEFAQKWLGKN
LVTFQTDANGQPVSKILVEEASNIANELYLGAVVDRASQRIVFMASTEGGVDIEKIAEETPELIHKAAIDPLVGPQAYQG
RELAFKLGLEGDQIKQFVKIFMGLGNMFAQYDLALLEINPLVVTAEGSLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
REAHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVNLHGGQPANFLDVGGGATKERVTEAFKIILSDSNVKAVLVNIFG
GIVRCDLIADGIIGAVEEVGVEVPVVVRLEGNNAPLGSQKLAESGLNIIAATSLTEAAEKVVAAAEGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=46.0559796437659, Blast_Score=349, Evalue=2e-96,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=43.8642297650131, Blast_Score=310, Evalue=1e-84,
Organism=Homo sapiens, GI294862256, Length=358, Percent_Identity=44.6927374301676, Blast_Score=300, Evalue=1e-81,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=77.0618556701031, Blast_Score=602, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=45.360824742268, Blast_Score=315, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=43.2569974554707, Blast_Score=310, Evalue=7e-85,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=41.3265306122449, Blast_Score=316, Evalue=3e-87,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=43.0025445292621, Blast_Score=305, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=43.0025445292621, Blast_Score=305, Evalue=3e-83,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=43.1472081218274, Blast_Score=304, Evalue=8e-83,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=43.1472081218274, Blast_Score=304, Evalue=8e-83,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=42.1319796954315, Blast_Score=296, Evalue=1e-80,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41384; Mature: 41384

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHEEEEEEEECCCCCCCCCE
ELHDTKEGVKEFAQKWLGKNLVTFQTDANGQPVSKILVEEASNIANELYLGAVVDRASQR
EECCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
IVFMASTEGGVDIEKIAEETPELIHKAAIDPLVGPQAYQGRELAFKLGLEGDQIKQFVKI
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
FMGLGNMFAQYDLALLEINPLVVTAEGSLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
HHHHHHHHHHHCEEEEEECCEEEEECCCEEEECCEEEECCCCCCCCCCHHHHCCCCCHHH
REAHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVNLHGGQPANFLDVGGGATKERVTE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKAVLVNIFGGIVRCDLIADGIIGAVEEVGVEVPVVVRLEGNNAPLGSQK
HHHHEECCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHH
LAESGLNIIAATSLTEAAEKVVAAAEGK
HHHCCCCEEEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHEEEEEEEECCCCCCCCCE
ELHDTKEGVKEFAQKWLGKNLVTFQTDANGQPVSKILVEEASNIANELYLGAVVDRASQR
EECCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
IVFMASTEGGVDIEKIAEETPELIHKAAIDPLVGPQAYQGRELAFKLGLEGDQIKQFVKI
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
FMGLGNMFAQYDLALLEINPLVVTAEGSLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
HHHHHHHHHHHCEEEEEECCEEEEECCCEEEECCEEEECCCCCCCCCCHHHHCCCCCHHH
REAHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVNLHGGQPANFLDVGGGATKERVTE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKAVLVNIFGGIVRCDLIADGIIGAVEEVGVEVPVVVRLEGNNAPLGSQK
HHHHEECCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHH
LAESGLNIIAATSLTEAAEKVVAAAEGK
HHHCCCCEEEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA