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The map label for this gene is gpt [H]

Identifier: 59711345

GI number: 59711345

Start: 805351

End: 805809

Strand: Direct

Name: gpt [H]

Synonym: VF_0738

Alternate gene names: 59711345

Gene position: 805351-805809 (Clockwise)

Preceding gene: 59711344

Following gene: 59711346

Centisome position: 27.79

GC content: 40.52

Gene sequence:

>459_bases
ATGGCTAATAAATTTGTAATCACTTGGGATAACATGCAGATGTATACTCGTCAGCTTGCTGAACAGTTACTTCCTGCCGA
TCAATGGAAAGGTATTTTGGCTGTGAGCCGTGGTGGTTTAGTTCCTGCTGCAATCTTGGCTCGTGAGTTAAATATTCGTC
ATGTTGATACAGTATGTATCTCAAGCTATGACCATGATCATCAGCGTGATATGACGGTTGTTAAAGCTATGGAAGGTGAC
GGTGAAGGTTTCATCATCATTGATGATCTAGTAGATAGCGGTGATACTGCGGTTAAATTACGTGAAATGTACCCTAAAGG
TAAATTAGTAACGGTATGTGCTAAACCTGCAGGCGTTCATCTAGTAGACGCTTATGTTGTAGATATCCCACAAGATACAT
GGATTGAACAACCTTGGGATATGGCGGTAACTTACGTCGATCCTATTGCTAAAAAATAA

Upstream 100 bases:

>100_bases
GTTCACATCAGTGTTTGGGTTCTAGCTGCATTATTCACGCTGAAATTTATTTTTACGGCATAGTCGTTGATGACTGTGTC
ACTTAGAGGTTTTGTCAATT

Downstream 100 bases:

>100_bases
TTAGCAAAAAATATTTTAATAAAATGACTCTTTTATAGGGTCATTTTTTTTATTCAAAACTTAATTTTATTCGCTTCTTC
ATATTCCTTATTCTTCTTTC

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MANKFVITWDNMQMYTRQLAEQLLPADQWKGILAVSRGGLVPAAILARELNIRHVDTVCISSYDHDHQRDMTVVKAMEGD
GEGFIIIDDLVDSGDTAVKLREMYPKGKLVTVCAKPAGVHLVDAYVVDIPQDTWIEQPWDMAVTYVDPIAKK

Sequences:

>Translated_152_residues
MANKFVITWDNMQMYTRQLAEQLLPADQWKGILAVSRGGLVPAAILARELNIRHVDTVCISSYDHDHQRDMTVVKAMEGD
GEGFIIIDDLVDSGDTAVKLREMYPKGKLVTVCAKPAGVHLVDAYVVDIPQDTWIEQPWDMAVTYVDPIAKK
>Mature_151_residues
ANKFVITWDNMQMYTRQLAEQLLPADQWKGILAVSRGGLVPAAILARELNIRHVDTVCISSYDHDHQRDMTVVKAMEGDG
EGFIIIDDLVDSGDTAVKLREMYPKGKLVTVCAKPAGVHLVDAYVVDIPQDTWIEQPWDMAVTYVDPIAKK

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786433, Length=152, Percent_Identity=69.0789473684211, Blast_Score=233, Evalue=6e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 17013; Mature: 16882

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKFVITWDNMQMYTRQLAEQLLPADQWKGILAVSRGGLVPAAILARELNIRHVDTVCI
CCCEEEEEECCHHHHHHHHHHHHCCHHHCCCEEEEECCCCCHHHHHHHHCCCEEEEEEEE
SSYDHDHQRDMTVVKAMEGDGEGFIIIDDLVDSGDTAVKLREMYPKGKLVTVCAKPAGVH
CCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCEEEEEHHCCCCCEEEEEECCCCEE
LVDAYVVDIPQDTWIEQPWDMAVTYVDPIAKK
EEEEEEEECCCCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
ANKFVITWDNMQMYTRQLAEQLLPADQWKGILAVSRGGLVPAAILARELNIRHVDTVCI
CCEEEEEECCHHHHHHHHHHHHCCHHHCCCEEEEECCCCCHHHHHHHHCCCEEEEEEEE
SSYDHDHQRDMTVVKAMEGDGEGFIIIDDLVDSGDTAVKLREMYPKGKLVTVCAKPAGVH
CCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCEEEEEHHCCCCCEEEEEECCCCEE
LVDAYVVDIPQDTWIEQPWDMAVTYVDPIAKK
EEEEEEEECCCCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA