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The map label for this gene is bolA [H]

Identifier: 59711331

GI number: 59711331

Start: 791029

End: 791343

Strand: Direct

Name: bolA [H]

Synonym: VF_0724

Alternate gene names: 59711331

Gene position: 791029-791343 (Clockwise)

Preceding gene: 59711323

Following gene: 59711332

Centisome position: 27.3

GC content: 38.1

Gene sequence:

>315_bases
ATGATTCAGCATCAAATTGAACAAAAATTACGCGAAGCGTTAGCGCCTTCTTATCTTAAAGTTCTAAATGAAAGCTATAT
GCATAACGTACCTGAAGGTTCTGAAAGCCATTTTAAGGTAATTGTAGTGAGCGACGAATTTGAAGGTAAACGTTTGATTG
CTCGCCATCGAGCTATTAATAACATTTTAGCTGAAGAATTGTCAGATCATATTCATGCTTTAGCCATTCATACGTATACA
GAAACAGAATGGCAAGCTCTAGATGCAGAGCAAGTTCCTCTTAGTCCCAACTGTATGGGCGGTGGAAAAGGTTAA

Upstream 100 bases:

>100_bases
TTCATAATGATTTGATCTTCAAATAGGGAAGGCTTCTAGCTATTGTCGCAAATGGTGTATAAAGTGGAAACAGAAGAATT
CAAATAAAGAAAGGAATTAT

Downstream 100 bases:

>100_bases
AAATGAAACGCTAATGTTTATTTTTTAACATAAAATAAATATAAAATAAGTCTGTTTGTTAAAAAATGACTAATATTTAA
TGTCATTGCTACTTATGGGG

Product: regulator of penicillin binding proteins and beta lactamase transcription (morphogene)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MIQHQIEQKLREALAPSYLKVLNESYMHNVPEGSESHFKVIVVSDEFEGKRLIARHRAINNILAEELSDHIHALAIHTYT
ETEWQALDAEQVPLSPNCMGGGKG

Sequences:

>Translated_104_residues
MIQHQIEQKLREALAPSYLKVLNESYMHNVPEGSESHFKVIVVSDEFEGKRLIARHRAINNILAEELSDHIHALAIHTYT
ETEWQALDAEQVPLSPNCMGGGKG
>Mature_104_residues
MIQHQIEQKLREALAPSYLKVLNESYMHNVPEGSESHFKVIVVSDEFEGKRLIARHRAINNILAEELSDHIHALAIHTYT
ETEWQALDAEQVPLSPNCMGGGKG

Specific function: Plays An Important Role In General Stress Response (Heat Shock, Acidic Stress, Oxidative Stress, Carbon-Starvation Stress And Osmotic Shock). Involved In Morphogenetic Pathway. Has A Role Is The Induction Of The Expression Of Daca (Pbp5), Dacc (Pbp6) And

COG id: COG0271

COG function: function code T; Stress-induced morphogen (activity unknown)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bolA/yrbA family [H]

Homologues:

Organism=Homo sapiens, GI7705638, Length=102, Percent_Identity=47.0588235294118, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI87081740, Length=102, Percent_Identity=57.843137254902, Blast_Score=124, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17541430, Length=96, Percent_Identity=48.9583333333333, Blast_Score=99, Evalue=5e-22,
Organism=Drosophila melanogaster, GI221459039, Length=105, Percent_Identity=44.7619047619048, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI78707212, Length=85, Percent_Identity=37.6470588235294, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002634 [H]

Pfam domain/function: PF01722 BolA [H]

EC number: NA

Molecular weight: Translated: 11731; Mature: 11731

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQHQIEQKLREALAPSYLKVLNESYMHNVPEGSESHFKVIVVSDEFEGKRLIARHRAIN
CCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
NILAEELSDHIHALAIHTYTETEWQALDAEQVPLSPNCMGGGKG
HHHHHHHHHHHHHHHEECCCCCCHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIQHQIEQKLREALAPSYLKVLNESYMHNVPEGSESHFKVIVVSDEFEGKRLIARHRAIN
CCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
NILAEELSDHIHALAIHTYTETEWQALDAEQVPLSPNCMGGGKG
HHHHHHHHHHHHHHHEECCCCCCHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7805867 [H]