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The map label for this gene is trpR

Identifier: 59711166

GI number: 59711166

Start: 608394

End: 608720

Strand: Direct

Name: trpR

Synonym: VF_0559

Alternate gene names: 59711166

Gene position: 608394-608720 (Clockwise)

Preceding gene: 59711165

Following gene: 59711171

Centisome position: 21.0

GC content: 38.53

Gene sequence:

>327_bases
ATGTCAGGTTCAGCAAAATATTCCGACTGGTCTCAAGTGATGACATTAATTGCAAATGCAGCAGAACAAGGAAATCATCA
ACCATTATTAACGATGTTGATGACGCCTGATGAACGTGAAGCATTGGTTGCTCGCGTAAATATTTTTCATGAGCTGTTAC
AGGGTGAATTGAGCCAGAGACAAATTAGTCAGCTATTAGGTGTGGGCGTTGCCACAATCACTCGAGGTTCAAATGAATTA
AAAAGCCATACTGATGAAGAGAAAGTATGGCTTATGGATTTATTAGAAAAGAGTACTAAAAGCGAGTTGGATGTAGAAAA
GGAATAA

Upstream 100 bases:

>100_bases
ATTGATAAGTTTAAATTCTAATAGCAATTGGTATTAAGCTTAAATAAATATAAAGTAGGGGACTTAATTGTCCCCTTTTT
TACAATTGTATGAGGATACT

Downstream 100 bases:

>100_bases
GAGCAAGAATAAGCGCTTGTTGATATACCGATGTTCTTGTTAGTAGGTTATTGGTTAGTAAGCCAATAGCCCCTCCTTTC
TGTTTAATGTTGTCGGTGTT

Product: Trp operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 108; Mature: 107

Protein sequence:

>108_residues
MSGSAKYSDWSQVMTLIANAAEQGNHQPLLTMLMTPDEREALVARVNIFHELLQGELSQRQISQLLGVGVATITRGSNEL
KSHTDEEKVWLMDLLEKSTKSELDVEKE

Sequences:

>Translated_108_residues
MSGSAKYSDWSQVMTLIANAAEQGNHQPLLTMLMTPDEREALVARVNIFHELLQGELSQRQISQLLGVGVATITRGSNEL
KSHTDEEKVWLMDLLEKSTKSELDVEKE
>Mature_107_residues
SGSAKYSDWSQVMTLIANAAEQGNHQPLLTMLMTPDEREALVARVNIFHELLQGELSQRQISQLLGVGVATITRGSNELK
SHTDEEKVWLMDLLEKSTKSELDVEKE

Specific function: This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription

COG id: COG2973

COG function: function code K; Trp operon repressor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpR family

Homologues:

Organism=Escherichia coli, GI1790854, Length=93, Percent_Identity=49.4623655913978, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: 250-750 50-300 [C]

Swissprot (AC and ID): TRPR_VIBF1 (Q5E7E2)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_203942.1
- ProteinModelPortal:   Q5E7E2
- SMR:   Q5E7E2
- STRING:   Q5E7E2
- GeneID:   3278286
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_0559
- NMPDR:   fig|312309.3.peg.608
- eggNOG:   COG2973
- HOGENOM:   HBG677773
- OMA:   NIFHELL
- PhylomeDB:   Q5E7E2
- ProtClustDB:   PRK01381
- BioCyc:   VFIS312309:VF0559-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00475
- InterPro:   IPR000831
- InterPro:   IPR013335
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1270.10
- PIRSF:   PIRSF003196
- ProDom:   PD012582
- TIGRFAMs:   TIGR01321

Pfam domain/function: PF01371 Trp_repressor; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 12097; Mature: 11966

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSAKYSDWSQVMTLIANAAEQGNHQPLLTMLMTPDEREALVARVNIFHELLQGELSQR
CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEHEEECCCHHHHHHHHHHHHHHHHHHHHHHH
QISQLLGVGVATITRGSNELKSHTDEEKVWLMDLLEKSTKSELDVEKE
HHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SGSAKYSDWSQVMTLIANAAEQGNHQPLLTMLMTPDEREALVARVNIFHELLQGELSQR
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEHEEECCCHHHHHHHHHHHHHHHHHHHHHHH
QISQLLGVGVATITRGSNELKSHTDEEKVWLMDLLEKSTKSELDVEKE
HHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA