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The map label for this gene is idi

Identifier: 59711010

GI number: 59711010

Start: 432599

End: 433144

Strand: Direct

Name: idi

Synonym: VF_0403

Alternate gene names: 59711010

Gene position: 432599-433144 (Clockwise)

Preceding gene: 59711009

Following gene: 59711016

Centisome position: 14.93

GC content: 37.0

Gene sequence:

>546_bases
ATGACAGAATATGTAGTTCTTGTGAATGAGCAAGGTGATGCCATTGGTACAATGGAAAAATTAGAAGCGCATGAAAAAGG
CTTGTTACATCTCGCTTTTTCAGTTTTGCTCTATCGTGAAACGGATTTAGGAAAAGAGTTTTTATTACAAAAGCGTGCCG
AATGTAAATACCATAGTAAGAACAAATGGAGCAATACCTGTTGTTCTCACCCTCGAGTGAATGAAAACGTAGAGGTGGCG
GGTACGCGACGTTTAAATGAAGAGATTGGTATTACTGGTGTTTTACCAGAGCAGTTCGTAAATCTTGGTTGGTTTATTTA
TCAAGCTGAATTAGAAAATGGATTGAGTGAGCATGAGCAAGATTATATTTTGATTGCTAATACTCCAGATGTGAGTTTTA
TATTGAACCCTGAAGAAGTCAGTGACATTCAGTGGTGGAGTGAAGCTGATATTGAAAAAGAAATGAAAGCAAACCCAGAT
ACTTTTTCTGTTTGGTTTCCTACTGTTTATAAGAAAGTACTTACTCACCTACAGCAAGTGAACTAA

Upstream 100 bases:

>100_bases
AAGAAGTTGCAGAACGCAACCAAGCGTAATTAATCATCCTTAAATTTTATCTAAGGCATACGGTCTTCTGTGTGCCTTTT
TCTTTTTTAGATGTGTAGAC

Downstream 100 bases:

>100_bases
GTCGATATTCTTTTATTAGATAAAAATAAGGCAGAAAAGATTCTGCCTTATTTCGTTTTAATTTAGTGTTCGATTATTTA
CGAACTGCAATAGCTTCGAT

Product: isopentenyl-diphosphate delta-isomerase

Products: NA

Alternate protein names: IPP isomerase; IPP:DMAPP isomerase; Isopentenyl pyrophosphate isomerase

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MTEYVVLVNEQGDAIGTMEKLEAHEKGLLHLAFSVLLYRETDLGKEFLLQKRAECKYHSKNKWSNTCCSHPRVNENVEVA
GTRRLNEEIGITGVLPEQFVNLGWFIYQAELENGLSEHEQDYILIANTPDVSFILNPEEVSDIQWWSEADIEKEMKANPD
TFSVWFPTVYKKVLTHLQQVN

Sequences:

>Translated_181_residues
MTEYVVLVNEQGDAIGTMEKLEAHEKGLLHLAFSVLLYRETDLGKEFLLQKRAECKYHSKNKWSNTCCSHPRVNENVEVA
GTRRLNEEIGITGVLPEQFVNLGWFIYQAELENGLSEHEQDYILIANTPDVSFILNPEEVSDIQWWSEADIEKEMKANPD
TFSVWFPTVYKKVLTHLQQVN
>Mature_180_residues
TEYVVLVNEQGDAIGTMEKLEAHEKGLLHLAFSVLLYRETDLGKEFLLQKRAECKYHSKNKWSNTCCSHPRVNENVEVAG
TRRLNEEIGITGVLPEQFVNLGWFIYQAELENGLSEHEQDYILIANTPDVSFILNPEEVSDIQWWSEADIEKEMKANPDT
FSVWFPTVYKKVLTHLQQVN

Specific function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)

COG id: COG1443

COG function: function code I; Isopentenyldiphosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Homo sapiens, GI40018633, Length=156, Percent_Identity=35.2564102564103, Blast_Score=78, Evalue=4e-15,
Organism=Homo sapiens, GI15147242, Length=164, Percent_Identity=30.4878048780488, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI1789255, Length=166, Percent_Identity=35.5421686746988, Blast_Score=90, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17554092, Length=177, Percent_Identity=33.8983050847458, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6325140, Length=204, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281362205, Length=192, Percent_Identity=30.7291666666667, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24648688, Length=192, Percent_Identity=30.7291666666667, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IDI_VIBF1 (Q5E7U8)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_203786.1
- ProteinModelPortal:   Q5E7U8
- SMR:   Q5E7U8
- STRING:   Q5E7U8
- GeneID:   3278113
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_0403
- NMPDR:   fig|312309.3.peg.403
- eggNOG:   COG1443
- HOGENOM:   HBG416977
- OMA:   HKAVSVF
- PhylomeDB:   Q5E7U8
- ProtClustDB:   CLSK740254
- BioCyc:   VFIS312309:VF0403-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00202
- InterPro:   IPR011876
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10
- PANTHER:   PTHR10885
- PIRSF:   PIRSF018427
- TIGRFAMs:   TIGR02150

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: =5.3.3.2

Molecular weight: Translated: 20902; Mature: 20771

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS51462 NUDIX

Important sites: ACT_SITE 68-68 ACT_SITE 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEYVVLVNEQGDAIGTMEKLEAHEKGLLHLAFSVLLYRETDLGKEFLLQKRAECKYHSK
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
NKWSNTCCSHPRVNENVEVAGTRRLNEEIGITGVLPEQFVNLGWFIYQAELENGLSEHEQ
CCCCCCCCCCCCCCCCEEEEECCCCHHHCCEEEECHHHHHHHHHEEEEHHHHCCHHHCCC
DYILIANTPDVSFILNPEEVSDIQWWSEADIEKEMKANPDTFSVWFPTVYKKVLTHLQQV
CEEEEECCCCEEEEECCHHHCCCCCCCCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHC
N
C
>Mature Secondary Structure 
TEYVVLVNEQGDAIGTMEKLEAHEKGLLHLAFSVLLYRETDLGKEFLLQKRAECKYHSK
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
NKWSNTCCSHPRVNENVEVAGTRRLNEEIGITGVLPEQFVNLGWFIYQAELENGLSEHEQ
CCCCCCCCCCCCCCCCEEEEECCCCHHHCCEEEECHHHHHHHHHEEEEHHHHCCHHHCCC
DYILIANTPDVSFILNPEEVSDIQWWSEADIEKEMKANPDTFSVWFPTVYKKVLTHLQQV
CEEEEECCCCEEEEECCHHHCCCCCCCCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA