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The map label for this gene is yrbG [H]

Identifier: 59711000

GI number: 59711000

Start: 425889

End: 426860

Strand: Reverse

Name: yrbG [H]

Synonym: VF_0393

Alternate gene names: 59711000

Gene position: 426860-425889 (Counterclockwise)

Preceding gene: 59711011

Following gene: 59710999

Centisome position: 14.73

GC content: 40.23

Gene sequence:

>972_bases
ATGACAGAGCTGCTCATGCCAACTCTACTTCTTATCGTCGGTCTATCTCTATTGGTTTGGGGCGCCGATAAACTGGTATT
TGGTTCTGCTGCCTTAGCGAGAAACTATGGTATTTCCCCTCTTGTAATTGGTATGACTATCTTAGCCATGGGTTCATCTG
CACCAGAAATGATGGTGTCAGCTGCAGCTGCTTTAGATGGAAAAACAGATACTGCGGTTGGTAACGTTATTGGTTCAAAC
ATTGCGAACATCGCGTTAATTTTAGGTATTACCGCCTTAATTAAACCTTTAGCAATCAGCTCAGCAATCATCCGTCGCGA
ACTACCATTAATGCTGATGGTTACGTTATTAGCTGGTGGTATTATGTTTAATAACTACCTTGGCTTTTATGAAGGTTTAT
TGTTAATTGGCCTTTTTGCTTGCTTCATCATTGCAATGCTATACATCAGTAAAAACGAACAACAAAACGGGGATATTCTT
CTTGAAGAACAAGAATCTGAAATCCCTGAAGGCGTGGCAAACGGTAAAGCACTTTTCTGGGTTGTTGTAGGTCTTATCTT
ACTTCCTGTGGGTGCAAACATGCTGATTGATAATGCCGTTGTTATCGCTAAATACTTTGGTATGAGTGAGTTAGTTATCG
GCTTAACGATCATTGCATTAGGTACGAGTCTTCCTGAGTTAGCGGCTTCTGTTGCCGGTGTACTTAAAGGTGAAGATGAT
ATGGCAGCAGGTAATATCATTGGCTCAAACGTATTTAATATTCTTGCCGTAATGGGGATTCCAGCATTAATTAATCCATC
AGAAATTAGTCCTGATCTTATGGGCCGTGATTTCTATGTAATGCTAGGTGTATCCATCTTATTACTCATCATGGCATTAG
GAAAAAGCCGCAGCATTAATCGCATAGAAGGCGGTATTTTAGTGACGTGTTTCTGTGTCTACCAAGGCTATTTATTTCTA
AATATGGGTTAA

Upstream 100 bases:

>100_bases
CCACGTAAAGCGCTCCTTTTTTCTTTCTTTTTTGTTAGAGAAACGTCAAAATTAGCGATTCAAACTAAAAAACATCTTTC
TACAAAAGGAAATTAACACA

Downstream 100 bases:

>100_bases
CCATTCTTTTGGACCCCATAAGTTTGATGAACAATAAAAATCATGAACTTATGGGGTATTTATCCCGATAATTTACCTTC
TTTTACCTACTCAATATTGA

Product: calcium/sodium:proton antiporter

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MTELLMPTLLLIVGLSLLVWGADKLVFGSAALARNYGISPLVIGMTILAMGSSAPEMMVSAAAALDGKTDTAVGNVIGSN
IANIALILGITALIKPLAISSAIIRRELPLMLMVTLLAGGIMFNNYLGFYEGLLLIGLFACFIIAMLYISKNEQQNGDIL
LEEQESEIPEGVANGKALFWVVVGLILLPVGANMLIDNAVVIAKYFGMSELVIGLTIIALGTSLPELAASVAGVLKGEDD
MAAGNIIGSNVFNILAVMGIPALINPSEISPDLMGRDFYVMLGVSILLLIMALGKSRSINRIEGGILVTCFCVYQGYLFL
NMG

Sequences:

>Translated_323_residues
MTELLMPTLLLIVGLSLLVWGADKLVFGSAALARNYGISPLVIGMTILAMGSSAPEMMVSAAAALDGKTDTAVGNVIGSN
IANIALILGITALIKPLAISSAIIRRELPLMLMVTLLAGGIMFNNYLGFYEGLLLIGLFACFIIAMLYISKNEQQNGDIL
LEEQESEIPEGVANGKALFWVVVGLILLPVGANMLIDNAVVIAKYFGMSELVIGLTIIALGTSLPELAASVAGVLKGEDD
MAAGNIIGSNVFNILAVMGIPALINPSEISPDLMGRDFYVMLGVSILLLIMALGKSRSINRIEGGILVTCFCVYQGYLFL
NMG
>Mature_322_residues
TELLMPTLLLIVGLSLLVWGADKLVFGSAALARNYGISPLVIGMTILAMGSSAPEMMVSAAAALDGKTDTAVGNVIGSNI
ANIALILGITALIKPLAISSAIIRRELPLMLMVTLLAGGIMFNNYLGFYEGLLLIGLFACFIIAMLYISKNEQQNGDILL
EEQESEIPEGVANGKALFWVVVGLILLPVGANMLIDNAVVIAKYFGMSELVIGLTIIALGTSLPELAASVAGVLKGEDDM
AAGNIIGSNVFNILAVMGIPALINPSEISPDLMGRDFYVMLGVSILLLIMALGKSRSINRIEGGILVTCFCVYQGYLFLN
MG

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1789587, Length=301, Percent_Identity=45.514950166113, Blast_Score=243, Evalue=9e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 33987; Mature: 33856

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELLMPTLLLIVGLSLLVWGADKLVFGSAALARNYGISPLVIGMTILAMGSSAPEMMVS
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHH
AAAALDGKTDTAVGNVIGSNIANIALILGITALIKPLAISSAIIRRELPLMLMVTLLAGG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
IMFNNYLGFYEGLLLIGLFACFIIAMLYISKNEQQNGDILLEEQESEIPEGVANGKALFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHCCCCHHCCCHHHHH
VVVGLILLPVGANMLIDNAVVIAKYFGMSELVIGLTIIALGTSLPELAASVAGVLKGEDD
HHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
MAAGNIIGSNVFNILAVMGIPALINPSEISPDLMGRDFYVMLGVSILLLIMALGKSRSIN
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCH
RIEGGILVTCFCVYQGYLFLNMG
HHCCCHHHHHHHHHHCEEEEECC
>Mature Secondary Structure 
TELLMPTLLLIVGLSLLVWGADKLVFGSAALARNYGISPLVIGMTILAMGSSAPEMMVS
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHH
AAAALDGKTDTAVGNVIGSNIANIALILGITALIKPLAISSAIIRRELPLMLMVTLLAGG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
IMFNNYLGFYEGLLLIGLFACFIIAMLYISKNEQQNGDILLEEQESEIPEGVANGKALFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHCCCCHHCCCHHHHH
VVVGLILLPVGANMLIDNAVVIAKYFGMSELVIGLTIIALGTSLPELAASVAGVLKGEDD
HHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
MAAGNIIGSNVFNILAVMGIPALINPSEISPDLMGRDFYVMLGVSILLLIMALGKSRSIN
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCH
RIEGGILVTCFCVYQGYLFLNMG
HHCCCHHHHHHHHHHCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]