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The map label for this gene is ssb [H]

Identifier: 59710960

GI number: 59710960

Start: 384488

End: 385021

Strand: Direct

Name: ssb [H]

Synonym: VF_0353

Alternate gene names: 59710960

Gene position: 384488-385021 (Clockwise)

Preceding gene: 172087658

Following gene: 59710962

Centisome position: 13.27

GC content: 46.44

Gene sequence:

>534_bases
ATGGCCAGCCGTGGTGTAAATAAAGTTATCCTTGTTGGTAACTTAGGGCAAGATCCTGAAATCCGTTACATGCCAAGTGG
CGGTGCGGTAGCGAATATTACAATTGCAACGTCTGAAACTTGGCGTGATAAGGCAACTGGTGAGCAACGTGAAAAAACAG
AATGGCACCGTGTTGCTCTGTTTGGCAAATTAGCAGAAGTTGCTGGTGAGTACTTACGTAAAGGCTCTCAAGTTTACGTT
GAGGGTCAATTACAAACTCGTAAATGGCAAGACCAGAATGGTCAAGACCGTTTTACAACAGAAGTAGTTGTTCAGGGCTT
TAACGGCGTAATGCAAATGCTTGGTGGTCGCGGACAAGGTGCTCCAGCTGGTGGTCAGCAACAGCAAGGTAATTGGGGCC
AGCCTCAACAACCTGCACAGCAGAATAATTTTGCTCCTCAACAACAGCAAGCTCCTCAACAACAAGCTCCACAAGCTGCT
CAACCTCAATACAATGAGCCGCCAATGGATTTTGATGATGACATCCCGTTCTAA

Upstream 100 bases:

>100_bases
TTAGGGGTATCAGATTTCACAATGAACGTGTTAGACTGATGACTACTGTATATATAACCGGGTGAAAACCGTTTTCCCCC
TTAATAATCTGGAGCAAACT

Downstream 100 bases:

>100_bases
TAATTGGACGTGTGTTAACTGATTTAAAATAAAAAAGCCTCGATAATATCGAGGCTTTTTTCTATCTGTTAGTTATCTAG
TGTTCTAATCTTTAATTTGA

Product: single-stranded DNA-binding protein

Products: NA

Alternate protein names: SSB; Helix-destabilizing protein [H]

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MASRGVNKVILVGNLGQDPEIRYMPSGGAVANITIATSETWRDKATGEQREKTEWHRVALFGKLAEVAGEYLRKGSQVYV
EGQLQTRKWQDQNGQDRFTTEVVVQGFNGVMQMLGGRGQGAPAGGQQQQGNWGQPQQPAQQNNFAPQQQQAPQQQAPQAA
QPQYNEPPMDFDDDIPF

Sequences:

>Translated_177_residues
MASRGVNKVILVGNLGQDPEIRYMPSGGAVANITIATSETWRDKATGEQREKTEWHRVALFGKLAEVAGEYLRKGSQVYV
EGQLQTRKWQDQNGQDRFTTEVVVQGFNGVMQMLGGRGQGAPAGGQQQQGNWGQPQQPAQQNNFAPQQQQAPQQQAPQAA
QPQYNEPPMDFDDDIPF
>Mature_176_residues
ASRGVNKVILVGNLGQDPEIRYMPSGGAVANITIATSETWRDKATGEQREKTEWHRVALFGKLAEVAGEYLRKGSQVYVE
GQLQTRKWQDQNGQDRFTTEVVVQGFNGVMQMLGGRGQGAPAGGQQQQGNWGQPQQPAQQNNFAPQQQQAPQQQAPQAAQ
PQYNEPPMDFDDDIPF

Specific function: This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair [H]

COG id: COG0629

COG function: function code L; Single-stranded DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SSB domain [H]

Homologues:

Organism=Homo sapiens, GI4507231, Length=109, Percent_Identity=33.9449541284404, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1790494, Length=182, Percent_Identity=75.2747252747253, Blast_Score=234, Evalue=3e-63,

Paralogues:

None

Copy number: 1622 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000424
- InterPro:   IPR011344 [H]

Pfam domain/function: PF00436 SSB [H]

EC number: NA

Molecular weight: Translated: 19555; Mature: 19424

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50935 SSB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRGVNKVILVGNLGQDPEIRYMPSGGAVANITIATSETWRDKATGEQREKTEWHRVAL
CCCCCCCEEEEECCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
FGKLAEVAGEYLRKGSQVYVEGQLQTRKWQDQNGQDRFTTEVVVQGFNGVMQMLGGRGQG
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
APAGGQQQQGNWGQPQQPAQQNNFAPQQQQAPQQQAPQAAQPQYNEPPMDFDDDIPF
CCCCCCCCCCCCCCCCCCCHHCCCCCHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASRGVNKVILVGNLGQDPEIRYMPSGGAVANITIATSETWRDKATGEQREKTEWHRVAL
CCCCCCEEEEECCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
FGKLAEVAGEYLRKGSQVYVEGQLQTRKWQDQNGQDRFTTEVVVQGFNGVMQMLGGRGQG
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
APAGGQQQQGNWGQPQQPAQQNNFAPQQQQAPQQQAPQAAQPQYNEPPMDFDDDIPF
CCCCCCCCCCCCCCCCCCCHHCCCCCHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9973335; 10952301 [H]