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The map label for this gene is gpmM

Identifier: 59710809

GI number: 59710809

Start: 223608

End: 225140

Strand: Reverse

Name: gpmM

Synonym: VF_0202

Alternate gene names: 59710809

Gene position: 225140-223608 (Counterclockwise)

Preceding gene: 59710810

Following gene: 59710768

Centisome position: 7.77

GC content: 44.29

Gene sequence:

>1533_bases
ATGTCAGCTAAGAAGCCTATGGCTCTAGTTATTCTTGATGGTTACGGTCACCGTGAAACTCAAGCAGATAACGCAATTAC
AAACGCAAACACTCCAGTTCTTGATGGCCTAATGGCTAATCAACCAAACACGCTAATTTCTGCATCTGGTATGGACGTTG
GTCTACCTGATGGTCAAATGGGTAACTCTGAAGTAGGTCACACTAACATCGGCGCTGGTCGTGTTGTATATCAAGACCTT
ACTCGTATCACTAAAGCTATCTCTGATGGTGAGTTCCAACAAAACGAAACACTTGTAAACGCTATCGACAAAGCAGTTAA
AGCAGGCAAAGCTGTTCACATCATGGGTCTTATGTCTCCAGGTGGCGTTCACTCTCATGAAGACCACATCTACGCAGCAG
TAGAAATGGCAGCAGCACGTGGCGCAGAGAAAATCTACCTACACTGTTTCCTAGACGGCCGTGATACACCACCACGTTCA
GCTGAGAACTCACTGAAAAACTTCCAAGAGCTATTCGCTAAACTAGGTAAAGGCCGTATTGCCTCTCTAGTTGGTCGTTA
CTACGCAATGGACCGTGACAACAACTGGGAACGTGTTCAAAAAGCTTACGACCTAATGACTGAAGCAAAAGCAGAATTCA
CTTTTGCAACAGCAGTTGAAGGTCTTGAAGCGGCTTACGCTCGTGAAGAGAACGATGAATTTGTTCAAGCAACAGAAATC
AAAGCGGAAGGCGAAGAATCAGCAGCTATCGTTGATGGCGATGCAGTTATCTTCATGAACTACCGTGCTGACCGTGCTCG
TCAAATCACTCGTACTTTCGTACCGTCTTTTGATGGCTTCACTCGTAACGTATTCCCAGCAATCGACTTCGTAATGTTGA
CTCAATACGCTGCTGATATTCCACTACTATGTGCATTCGCTCCTGCTTCTCTAGAAAACACATACGGTGAGTGGTTATCT
AAAGAAGGTAAAACTCAACTACGTATTTCTGAAACTGAAAAATACGCACACGTTACTTTCTTCTTCAATGGCGGCATCGA
AGATGAGTTTGAAGGTGAAGAACGTCAACTAGTTGCTTCTCCAAAAGTAGCGACTTACGATCTACAACCTGAAATGAGCG
CACCTGAGCTAACTGAAAAATTAGTTGCAGCTATCAAGTCTGGTAAATACGACGCTATCGTTTGTAACTTCCCTAACTGT
GACATGGTTGGCCACACTGGCGTATACGATGCAGCAGTTAAAGCCGTTGAATCTCTAGATGAGTGTATCGGTAAAGTTGT
TGAAGCAATCAAAGAAGTTGATGGCCAACTACTTATCACTGCTGACCACGGTAACGCTGAAATGATGATCGACCCTGAAA
CAGGCGGCGTTCACACAGCTCACACTAATCTTCCAGTACCTCTAATCTACGTAGGTAGCAAAGCGGTTGAGTTTAAAGAA
GGCGGTAAACTGTCTGACCTAGCTCCAACGATGCTAGCACTAACAGATACAGCGATTCCTGCTGAAATGTCTGGTGAAGT
TCTTTTTAAATAA

Upstream 100 bases:

>100_bases
AAGCGTCCTGCTCTTCCCCTAGCCCATTTTCAAACTTTGTAGTAAAATTACACAAAGTTATTTATTCGAATTTATTAAGT
TATTGACGAGGAACACCTTT

Downstream 100 bases:

>100_bases
GAAAAGAGCAGGGACGAGAGGCGAGGACGCTTCGCTCAAGGAGCGAGGAAAAGCTTTAAATCGTCGATGAAATAAAAAAG
CCCACAGGTTTATAGCCTGT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MSAKKPMALVILDGYGHRETQADNAITNANTPVLDGLMANQPNTLISASGMDVGLPDGQMGNSEVGHTNIGAGRVVYQDL
TRITKAISDGEFQQNETLVNAIDKAVKAGKAVHIMGLMSPGGVHSHEDHIYAAVEMAAARGAEKIYLHCFLDGRDTPPRS
AENSLKNFQELFAKLGKGRIASLVGRYYAMDRDNNWERVQKAYDLMTEAKAEFTFATAVEGLEAAYAREENDEFVQATEI
KAEGEESAAIVDGDAVIFMNYRADRARQITRTFVPSFDGFTRNVFPAIDFVMLTQYAADIPLLCAFAPASLENTYGEWLS
KEGKTQLRISETEKYAHVTFFFNGGIEDEFEGEERQLVASPKVATYDLQPEMSAPELTEKLVAAIKSGKYDAIVCNFPNC
DMVGHTGVYDAAVKAVESLDECIGKVVEAIKEVDGQLLITADHGNAEMMIDPETGGVHTAHTNLPVPLIYVGSKAVEFKE
GGKLSDLAPTMLALTDTAIPAEMSGEVLFK

Sequences:

>Translated_510_residues
MSAKKPMALVILDGYGHRETQADNAITNANTPVLDGLMANQPNTLISASGMDVGLPDGQMGNSEVGHTNIGAGRVVYQDL
TRITKAISDGEFQQNETLVNAIDKAVKAGKAVHIMGLMSPGGVHSHEDHIYAAVEMAAARGAEKIYLHCFLDGRDTPPRS
AENSLKNFQELFAKLGKGRIASLVGRYYAMDRDNNWERVQKAYDLMTEAKAEFTFATAVEGLEAAYAREENDEFVQATEI
KAEGEESAAIVDGDAVIFMNYRADRARQITRTFVPSFDGFTRNVFPAIDFVMLTQYAADIPLLCAFAPASLENTYGEWLS
KEGKTQLRISETEKYAHVTFFFNGGIEDEFEGEERQLVASPKVATYDLQPEMSAPELTEKLVAAIKSGKYDAIVCNFPNC
DMVGHTGVYDAAVKAVESLDECIGKVVEAIKEVDGQLLITADHGNAEMMIDPETGGVHTAHTNLPVPLIYVGSKAVEFKE
GGKLSDLAPTMLALTDTAIPAEMSGEVLFK
>Mature_509_residues
SAKKPMALVILDGYGHRETQADNAITNANTPVLDGLMANQPNTLISASGMDVGLPDGQMGNSEVGHTNIGAGRVVYQDLT
RITKAISDGEFQQNETLVNAIDKAVKAGKAVHIMGLMSPGGVHSHEDHIYAAVEMAAARGAEKIYLHCFLDGRDTPPRSA
ENSLKNFQELFAKLGKGRIASLVGRYYAMDRDNNWERVQKAYDLMTEAKAEFTFATAVEGLEAAYAREENDEFVQATEIK
AEGEESAAIVDGDAVIFMNYRADRARQITRTFVPSFDGFTRNVFPAIDFVMLTQYAADIPLLCAFAPASLENTYGEWLSK
EGKTQLRISETEKYAHVTFFFNGGIEDEFEGEERQLVASPKVATYDLQPEMSAPELTEKLVAAIKSGKYDAIVCNFPNCD
MVGHTGVYDAAVKAVESLDECIGKVVEAIKEVDGQLLITADHGNAEMMIDPETGGVHTAHTNLPVPLIYVGSKAVEFKEG
GKLSDLAPTMLALTDTAIPAEMSGEVLFK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=510, Percent_Identity=70.9803921568627, Blast_Score=754, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17507741, Length=514, Percent_Identity=46.4980544747082, Blast_Score=435, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI32564249, Length=514, Percent_Identity=46.4980544747082, Blast_Score=435, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_VIBF1 (Q5E8E9)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_203585.1
- ProteinModelPortal:   Q5E8E9
- SMR:   Q5E8E9
- STRING:   Q5E8E9
- GeneID:   3277192
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_0202
- NMPDR:   fig|312309.3.peg.202
- eggNOG:   COG0696
- HOGENOM:   HBG613255
- OMA:   DNKTDEF
- PhylomeDB:   Q5E8E9
- ProtClustDB:   PRK05434
- BioCyc:   VFIS312309:VF0202-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 55403; Mature: 55272

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: ACT_SITE 63-63

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKKPMALVILDGYGHRETQADNAITNANTPVLDGLMANQPNTLISASGMDVGLPDGQM
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCCCCC
GNSEVGHTNIGAGRVVYQDLTRITKAISDGEFQQNETLVNAIDKAVKAGKAVHIMGLMSP
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCC
GGVHSHEDHIYAAVEMAAARGAEKIYLHCFLDGRDTPPRSAENSLKNFQELFAKLGKGRI
CCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHH
ASLVGRYYAMDRDNNWERVQKAYDLMTEAKAEFTFATAVEGLEAAYAREENDEFVQATEI
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHCCCCCCEEEEEEE
KAEGEESAAIVDGDAVIFMNYRADRARQITRTFVPSFDGFTRNVFPAIDFVMLTQYAADI
ECCCCCCEEEEECCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
PLLCAFAPASLENTYGEWLSKEGKTQLRISETEKYAHVTFFFNGGIEDEFEGEERQLVAS
CEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCCEEEEC
PKVATYDLQPEMSAPELTEKLVAAIKSGKYDAIVCNFPNCDMVGHTGVYDAAVKAVESLD
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
ECIGKVVEAIKEVDGQLLITADHGNAEMMIDPETGGVHTAHTNLPVPLIYVGSKAVEFKE
HHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEECCCCEEEEEECCCEEECCC
GGKLSDLAPTMLALTDTAIPAEMSGEVLFK
CCCCCHHHHHHHHHCCCCCCCCCCCCEECC
>Mature Secondary Structure 
SAKKPMALVILDGYGHRETQADNAITNANTPVLDGLMANQPNTLISASGMDVGLPDGQM
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCCCCC
GNSEVGHTNIGAGRVVYQDLTRITKAISDGEFQQNETLVNAIDKAVKAGKAVHIMGLMSP
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCC
GGVHSHEDHIYAAVEMAAARGAEKIYLHCFLDGRDTPPRSAENSLKNFQELFAKLGKGRI
CCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHH
ASLVGRYYAMDRDNNWERVQKAYDLMTEAKAEFTFATAVEGLEAAYAREENDEFVQATEI
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHCCCCCCEEEEEEE
KAEGEESAAIVDGDAVIFMNYRADRARQITRTFVPSFDGFTRNVFPAIDFVMLTQYAADI
ECCCCCCEEEEECCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
PLLCAFAPASLENTYGEWLSKEGKTQLRISETEKYAHVTFFFNGGIEDEFEGEERQLVAS
CEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCCEEEEC
PKVATYDLQPEMSAPELTEKLVAAIKSGKYDAIVCNFPNCDMVGHTGVYDAAVKAVESLD
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
ECIGKVVEAIKEVDGQLLITADHGNAEMMIDPETGGVHTAHTNLPVPLIYVGSKAVEFKE
HHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEECCCCEEEEEECCCEEECCC
GGKLSDLAPTMLALTDTAIPAEMSGEVLFK
CCCCCHHHHHHHHHCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA