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The map label for this gene is nahA [H]

Identifier: 59710644

GI number: 59710644

Start: 43328

End: 45775

Strand: Reverse

Name: nahA [H]

Synonym: VF_0037

Alternate gene names: 59710644

Gene position: 45775-43328 (Counterclockwise)

Preceding gene: 59710645

Following gene: 59710632

Centisome position: 1.58

GC content: 40.03

Gene sequence:

>2448_bases
ATGAAAAAAACACTTTTAACTCTTTCGATTTCAAGCTTTCTTTTTAGTGCATCATCCCTCGCTTCAGCTCCCAATACAAA
GTTAAACTTGATGCCATACCCTCAATCAGTAGAGTTAAATTCAGGCCAATTAGAAATTACTAGTGATTTCAGTATTTATA
TCGATGGTTATAAATCAGAGCGCATTCAGCAACTTGCCTTACGTATTATTCAACGTGTAGAAGCTCAAACTGGATTACCA
CTACTTACTCCTTTTGCTTCATCTAAAAAGGAAGCAACACTAATTATCGATGTGAGTAAGGCGGCCAAAAATAAAATTCA
AGATAACGACATTGACGAGTCTTACGAATTAACCATCAATAAAAAACAAATCATTTTAGAATCTGATCGTCCATACGGAG
CACTCCGTGGTGCAGAGACTTTTCTTCAATTAATCAACACATCCAAAGCGGGTTACTTTGTTCCTCAAGTAAATATTGAA
GATGAACCTCGTTTCCCATGGCGTGGAGCTTCATTTGACTCCTCTCGTCACTTTGTCACCGTTGATACAATAAAACGTCA
GATTGATGGTTTTGCTTCCGCAAAAATGAATGTTTTTCATTGGCACCTATGGGATGACCAAGCAATCCGAATTCAAATCG
AAAGTTACCCTAAGCTGTGGGAGAAAACTGCCGATGGTGATTTCTATACAAAAGAAGAAATCAAAGACGTTGTTGAATAC
GCCCGCCTACGCGGTATTCGAGTAATTCCTGAGATCTCATTACCTGGTCACGCTTCAGCTGTTGCTCATGCTTACCCTGA
ATTAATGTCTGGAGAAGGTGAACAATCTTACGATCAACAACGCGCTTGGGGTGTTTTTGTTCCTCTAATGAATCCTATTA
ACCCTGAACTCTATGTCTTCTTCGACAAAGTATTCAGTGAGGTAACTGAGCTGTTCCCAGATGAATACATTCACATTGGT
GGTGATGAGCCAAATTACCAACAATGGACAGATAATAAAGAAATCCAAGCATTCATCGCAGAAAATAATATTGATGGTAA
CCGTGGTTTACAGTCATACCTAAATGCACGCATTGAAAAAATGCTAAACAAGAAAGGTAAGAAGATCATGGGCTGGGATG
AGATTTGGCATAAAGATCTGCCAACATCGATTGTCATTCAAAGCTGGCGTGGACATGACAGTATTGGTCGAGCAGCAAAA
GAAGGTTATACCGGATTACTTTCAACGGGGTTCTATTTAGATCAACCGCAACCAACCAGCTACCATTATCGTAATGACCC
TATGCCAAAGGGACCACAAGTCGATGACCAACTGCATAGTGGAGAAACATTCGAAACCTACACTTGGCAGAAGCCAAGAG
GCAAAGGTGGTCCACGTAAAGGTACCCTAACTATCATTACCGATAAGAATGGTGATGCTCGTGCCTTTACTGATTACAAC
GGAAAATCACGAGCTAAAGTCGATATCATGGAATACACCAAAGGTGAGTCATTCCGTGGTCATTTTGATAACTTCATGTC
TTACACCGAATTTAATCTAATCTTCAATAACGGCAACATTAAAAAAGAAAGCTACCAGCTAGTCGGAAATGTTCGCTGGC
CAACCACAGGTGAAATGACCGCAAGTTCATCAATCAAGAACTCAGTGATTCCAGCTCCTAATGGTGGCTATCCTGTTGCT
TTAAATAAAGATGAAGAAAAACTTATTCTTGGTGGTGAAGCTGCTATCTGGGCAGAAAACTACGACGACCTAACTGTTGA
AGGTCGAATTTGGCCTAGAACTTATGCCGTTGCTGAACGTTTATGGTCAGCTGAAGAGCTTACCGATGAAGACAGCATGT
ACCAACGCCTACAGGCAATGGACAGCTGGGCAACGATTTCTGTTGGCTTACAACATCAAACCAATAGCTATAAGCAGTAT
TTACGTATTGCTAACGGCGGTGATGTGTCTGCACTGATGAGTTTTGCAAACTATGCAGAACCTGCCCAATACTATGCTCG
TAACTGGGCGAAGTATAATTCTACCGATCCAAAAGGAGAACTATACAATCAATACGAAAGATTAAATCGCTTTGCAGACG
CAGTTCCAGTGGAGAGTTTTGCAGTATTAGAAATGATAAAACTTGCAAAGACGGCGATCAATGATCAGAGTGATTTAAAA
GCACTACAAAAACATTACCAAACTGTCTTAGAGAGTGCGCAAAAATCAGAAGTCATGTTTAAAAATAATGTATCTTCTTT
AGATACTGTACTGCTAGCCCAAAAACATGTTGAGGTAGCAAAAGCAACGTTAGCAGTTATTAATGAGCTTGAAAAAGGCC
AACAGCCAACATCGACACAACTAGATAAACTATTATCTATTACTACAAATGCATCAGGAATGTACGATGAAATGATTGTT
GCTATTGTTCGCCCAACAGAAGAGTTAGTTCGTCAGTTACGTAAGTAA

Upstream 100 bases:

>100_bases
CACTCAATGTTATTAATACAAACCATAATTTGGTCACATACAAAGTTCTCTTTATACGTAATCCTTCCTTGGAATTTAAA
GGAATATAGGACTACACATA

Downstream 100 bases:

>100_bases
CTGAGCTAAAAATCAACAAACTAAATAAAGTACTACTTAAGTTAAGTAGTACTTTAATTTACTGCTCTCAGGTTATTTTT
ATATCCAATTTAATAGATGT

Product: beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 815; Mature: 815

Protein sequence:

>815_residues
MKKTLLTLSISSFLFSASSLASAPNTKLNLMPYPQSVELNSGQLEITSDFSIYIDGYKSERIQQLALRIIQRVEAQTGLP
LLTPFASSKKEATLIIDVSKAAKNKIQDNDIDESYELTINKKQIILESDRPYGALRGAETFLQLINTSKAGYFVPQVNIE
DEPRFPWRGASFDSSRHFVTVDTIKRQIDGFASAKMNVFHWHLWDDQAIRIQIESYPKLWEKTADGDFYTKEEIKDVVEY
ARLRGIRVIPEISLPGHASAVAHAYPELMSGEGEQSYDQQRAWGVFVPLMNPINPELYVFFDKVFSEVTELFPDEYIHIG
GDEPNYQQWTDNKEIQAFIAENNIDGNRGLQSYLNARIEKMLNKKGKKIMGWDEIWHKDLPTSIVIQSWRGHDSIGRAAK
EGYTGLLSTGFYLDQPQPTSYHYRNDPMPKGPQVDDQLHSGETFETYTWQKPRGKGGPRKGTLTIITDKNGDARAFTDYN
GKSRAKVDIMEYTKGESFRGHFDNFMSYTEFNLIFNNGNIKKESYQLVGNVRWPTTGEMTASSSIKNSVIPAPNGGYPVA
LNKDEEKLILGGEAAIWAENYDDLTVEGRIWPRTYAVAERLWSAEELTDEDSMYQRLQAMDSWATISVGLQHQTNSYKQY
LRIANGGDVSALMSFANYAEPAQYYARNWAKYNSTDPKGELYNQYERLNRFADAVPVESFAVLEMIKLAKTAINDQSDLK
ALQKHYQTVLESAQKSEVMFKNNVSSLDTVLLAQKHVEVAKATLAVINELEKGQQPTSTQLDKLLSITTNASGMYDEMIV
AIVRPTEELVRQLRK

Sequences:

>Translated_815_residues
MKKTLLTLSISSFLFSASSLASAPNTKLNLMPYPQSVELNSGQLEITSDFSIYIDGYKSERIQQLALRIIQRVEAQTGLP
LLTPFASSKKEATLIIDVSKAAKNKIQDNDIDESYELTINKKQIILESDRPYGALRGAETFLQLINTSKAGYFVPQVNIE
DEPRFPWRGASFDSSRHFVTVDTIKRQIDGFASAKMNVFHWHLWDDQAIRIQIESYPKLWEKTADGDFYTKEEIKDVVEY
ARLRGIRVIPEISLPGHASAVAHAYPELMSGEGEQSYDQQRAWGVFVPLMNPINPELYVFFDKVFSEVTELFPDEYIHIG
GDEPNYQQWTDNKEIQAFIAENNIDGNRGLQSYLNARIEKMLNKKGKKIMGWDEIWHKDLPTSIVIQSWRGHDSIGRAAK
EGYTGLLSTGFYLDQPQPTSYHYRNDPMPKGPQVDDQLHSGETFETYTWQKPRGKGGPRKGTLTIITDKNGDARAFTDYN
GKSRAKVDIMEYTKGESFRGHFDNFMSYTEFNLIFNNGNIKKESYQLVGNVRWPTTGEMTASSSIKNSVIPAPNGGYPVA
LNKDEEKLILGGEAAIWAENYDDLTVEGRIWPRTYAVAERLWSAEELTDEDSMYQRLQAMDSWATISVGLQHQTNSYKQY
LRIANGGDVSALMSFANYAEPAQYYARNWAKYNSTDPKGELYNQYERLNRFADAVPVESFAVLEMIKLAKTAINDQSDLK
ALQKHYQTVLESAQKSEVMFKNNVSSLDTVLLAQKHVEVAKATLAVINELEKGQQPTSTQLDKLLSITTNASGMYDEMIV
AIVRPTEELVRQLRK
>Mature_815_residues
MKKTLLTLSISSFLFSASSLASAPNTKLNLMPYPQSVELNSGQLEITSDFSIYIDGYKSERIQQLALRIIQRVEAQTGLP
LLTPFASSKKEATLIIDVSKAAKNKIQDNDIDESYELTINKKQIILESDRPYGALRGAETFLQLINTSKAGYFVPQVNIE
DEPRFPWRGASFDSSRHFVTVDTIKRQIDGFASAKMNVFHWHLWDDQAIRIQIESYPKLWEKTADGDFYTKEEIKDVVEY
ARLRGIRVIPEISLPGHASAVAHAYPELMSGEGEQSYDQQRAWGVFVPLMNPINPELYVFFDKVFSEVTELFPDEYIHIG
GDEPNYQQWTDNKEIQAFIAENNIDGNRGLQSYLNARIEKMLNKKGKKIMGWDEIWHKDLPTSIVIQSWRGHDSIGRAAK
EGYTGLLSTGFYLDQPQPTSYHYRNDPMPKGPQVDDQLHSGETFETYTWQKPRGKGGPRKGTLTIITDKNGDARAFTDYN
GKSRAKVDIMEYTKGESFRGHFDNFMSYTEFNLIFNNGNIKKESYQLVGNVRWPTTGEMTASSSIKNSVIPAPNGGYPVA
LNKDEEKLILGGEAAIWAENYDDLTVEGRIWPRTYAVAERLWSAEELTDEDSMYQRLQAMDSWATISVGLQHQTNSYKQY
LRIANGGDVSALMSFANYAEPAQYYARNWAKYNSTDPKGELYNQYERLNRFADAVPVESFAVLEMIKLAKTAINDQSDLK
ALQKHYQTVLESAQKSEVMFKNNVSSLDTVLLAQKHVEVAKATLAVINELEKGQQPTSTQLDKLLSITTNASGMYDEMIV
AIVRPTEELVRQLRK

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI189181666, Length=352, Percent_Identity=34.375, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI4504373, Length=315, Percent_Identity=33.968253968254, Blast_Score=188, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17569815, Length=321, Percent_Identity=33.6448598130841, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI17933586, Length=400, Percent_Identity=27.75, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI45551090, Length=361, Percent_Identity=28.5318559556787, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24653074, Length=361, Percent_Identity=28.5318559556787, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24657468, Length=250, Percent_Identity=30, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17647501, Length=250, Percent_Identity=30, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281365639, Length=291, Percent_Identity=28.5223367697594, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24657474, Length=291, Percent_Identity=28.5223367697594, Blast_Score=121, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 92430; Mature: 92430

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLLTLSISSFLFSASSLASAPNTKLNLMPYPQSVELNSGQLEITSDFSIYIDGYKSE
CCCEEEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCEEEEECCEEEEEECCHHH
RIQQLALRIIQRVEAQTGLPLLTPFASSKKEATLIIDVSKAAKNKIQDNDIDESYELTIN
HHHHHHHHHHHHHHHHCCCCEECCCCCCCCCEEEEEEECHHHHCCCCCCCCCCCEEEEEE
KKQIILESDRPYGALRGAETFLQLINTSKAGYFVPQVNIEDEPRFPWRGASFDSSRHFVT
CEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEE
VDTIKRQIDGFASAKMNVFHWHLWDDQAIRIQIESYPKLWEKTADGDFYTKEEIKDVVEY
HHHHHHHHCCHHCCCEEEEEEEEECCCEEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHH
ARLRGIRVIPEISLPGHASAVAHAYPELMSGEGEQSYDQQRAWGVFVPLMNPINPELYVF
HHHCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCEEEEECCCCCCCCEEEH
FDKVFSEVTELFPDEYIHIGGDEPNYQQWTDNKEIQAFIAENNIDGNRGLQSYLNARIEK
HHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
MLNKKGKKIMGWDEIWHKDLPTSIVIQSWRGHDSIGRAAKEGYTGLLSTGFYLDQPQPTS
HHHHCCCEEECHHHHHHCCCCHHHEEECCCCCCHHHHHHHHCCCCHHHCCEEECCCCCCC
YHYRNDPMPKGPQVDDQLHSGETFETYTWQKPRGKGGPRKGTLTIITDKNGDARAFTDYN
CCCCCCCCCCCCCCCCHHCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCEEEECCC
GKSRAKVDIMEYTKGESFRGHFDNFMSYTEFNLIFNNGNIKKESYQLVGNVRWPTTGEMT
CCCCCEEEEEECCCCCCCCCHHHHHHCEEEEEEEEECCCCCCCHHEEEECCCCCCCCCCC
ASSSIKNSVIPAPNGGYPVALNKDEEKLILGGEAAIWAENYDDLTVEGRIWPRTYAVAER
CCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCEEEEECCCCCEEEECEECCHHHHHHHH
LWSAEELTDEDSMYQRLQAMDSWATISVGLQHQTNSYKQYLRIANGGDVSALMSFANYAE
HHCHHHCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCC
PAQYYARNWAKYNSTDPKGELYNQYERLNRFADAVPVESFAVLEMIKLAKTAINDQSDLK
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHH
ALQKHYQTVLESAQKSEVMFKNNVSSLDTVLLAQKHVEVAKATLAVINELEKGQQPTSTQ
HHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LDKLLSITTNASGMYDEMIVAIVRPTEELVRQLRK
HHHHHHHCCCCCCHHHHHHHHEECCHHHHHHHHCC
>Mature Secondary Structure
MKKTLLTLSISSFLFSASSLASAPNTKLNLMPYPQSVELNSGQLEITSDFSIYIDGYKSE
CCCEEEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCEEEEECCEEEEEECCHHH
RIQQLALRIIQRVEAQTGLPLLTPFASSKKEATLIIDVSKAAKNKIQDNDIDESYELTIN
HHHHHHHHHHHHHHHHCCCCEECCCCCCCCCEEEEEEECHHHHCCCCCCCCCCCEEEEEE
KKQIILESDRPYGALRGAETFLQLINTSKAGYFVPQVNIEDEPRFPWRGASFDSSRHFVT
CEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEE
VDTIKRQIDGFASAKMNVFHWHLWDDQAIRIQIESYPKLWEKTADGDFYTKEEIKDVVEY
HHHHHHHHCCHHCCCEEEEEEEEECCCEEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHH
ARLRGIRVIPEISLPGHASAVAHAYPELMSGEGEQSYDQQRAWGVFVPLMNPINPELYVF
HHHCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCEEEEECCCCCCCCEEEH
FDKVFSEVTELFPDEYIHIGGDEPNYQQWTDNKEIQAFIAENNIDGNRGLQSYLNARIEK
HHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
MLNKKGKKIMGWDEIWHKDLPTSIVIQSWRGHDSIGRAAKEGYTGLLSTGFYLDQPQPTS
HHHHCCCEEECHHHHHHCCCCHHHEEECCCCCCHHHHHHHHCCCCHHHCCEEECCCCCCC
YHYRNDPMPKGPQVDDQLHSGETFETYTWQKPRGKGGPRKGTLTIITDKNGDARAFTDYN
CCCCCCCCCCCCCCCCHHCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCEEEECCC
GKSRAKVDIMEYTKGESFRGHFDNFMSYTEFNLIFNNGNIKKESYQLVGNVRWPTTGEMT
CCCCCEEEEEECCCCCCCCCHHHHHHCEEEEEEEEECCCCCCCHHEEEECCCCCCCCCCC
ASSSIKNSVIPAPNGGYPVALNKDEEKLILGGEAAIWAENYDDLTVEGRIWPRTYAVAER
CCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCEEEEECCCCCEEEECEECCHHHHHHHH
LWSAEELTDEDSMYQRLQAMDSWATISVGLQHQTNSYKQYLRIANGGDVSALMSFANYAE
HHCHHHCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCC
PAQYYARNWAKYNSTDPKGELYNQYERLNRFADAVPVESFAVLEMIKLAKTAINDQSDLK
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHH
ALQKHYQTVLESAQKSEVMFKNNVSSLDTVLLAQKHVEVAKATLAVINELEKGQQPTSTQ
HHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LDKLLSITTNASGMYDEMIVAIVRPTEELVRQLRK
HHHHHHHCCCCCCHHHHHHHHEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]