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The map label for this gene is rpoC

Identifier: 172087772

GI number: 172087772

Start: 2695759

End: 2699964

Strand: Reverse

Name: rpoC

Synonym: VF_2412

Alternate gene names: 172087772

Gene position: 2699964-2695759 (Counterclockwise)

Preceding gene: 172087773

Following gene: 59713015

Centisome position: 93.18

GC content: 43.98

Gene sequence:

>4206_bases
GTGAAAGACTTATTAAAGTTTCTGAAAGCACAACACAAGACTGAAGAATTTGATGCAATCAAAATCGGTCTTGCTTCACC
TGACCAAATTCGTTCATGGTCTTTTGGTGAAGTTAAAAAGCCAGAAACAATCAACTATCGTACCTTTAAGCCAGAACGTG
ACGGTCTTTTCTGTGCACGTATCTTTGGCCCAGTTAAAGACTACGAATGCTTATGTGGTAAATACAAACGCCTTAAGCAC
CGTGGTGTTATCTGTGAAAAATGTGGCGTAGAAGTAACGCAAACTAAAGTTCGTCGTGACCGTATGGGCCACATCGAATT
AGCGTCTCCAGTTGCGCACATCTGGTTCCTGAAGTCACTGCCGTCTCGTATTGGTTTGTTAATGGACATCCCACTACGTG
ATATCGAGCGTGTACTTTACTTTGAATCATATGTGGTTACTGAGCCAGGTATGACTGATCTAGAACGCAGCCAACTTCTT
TCTGAAGAAGAATATCTTGATAAGCTAGAAGAGTTCGGTGACGAATTCACAGCTAAGATGGGTGCGGAAGCGATCAAAGA
TCTGCTAGCGTCTATGGACATGCAAGCAGAGATCGAAGACATGCGTGAAGAGTTAGAAACTACTAACTCTGAAACAAAAC
GTAAAAAAGTAACTAAGCGTCTGAAACTAGTAGAAGCTTTCGTTCAATCTGGTAACAACCCAGAGTGGATGATTCTTACT
GTTCTACCAGTTCTTCCGCCAGATCTTCGTCCTCTAGTACCACTAGATGGCGGTCGTTTTGCTACGTCTGATCTAAATGA
CTTATACCGTCGTGTGATTAACCGTAACAACCGTTTGAAGCGTCTTTTAGACTTAGCTGCACCAGACATTATCGTACGTA
ACGAAAAACGTATGCTTCAAGAGTCTGTTGATGCGCTGCTTGATAACGGTCGTCGTGGTCGTGCGATCACAGGTTCTAAC
AAACGTCCTCTTAAATCTCTTGCTGATATGATCAAGGGTAAACAAGGTCGTTTCCGTCAGAACTTGCTTGGTAAACGTGT
AGACTACTCTGGTCGTTCTGTAATCACAGTAGGTCCATACCTTCGTCTACATCAGTGTGGTCTTCCTAAGAAGATGGCAC
TTGAACTATTTAAACCATTTATCTACAGCAAGTTAGAAGGTCGTGGTCTTGCTACGACAATCAAAGCTGCTAAGAAAATG
GTAGAGCGCGAGGAAGCGATCGTTTGGGATATCCTAGATGACGTAATCCGTGAACACCCAGTACTACTTAACCGTGCACC
GACACTTCACCGTCTAGGTATCCAAGCGTTTGAACCAGTACTAATCGAAGGTAAAGCGATTCAGCTTCACCCACTAGTGT
GTGCGGCATATAACGCCGACTTCGATGGTGACCAGATGGCGGTACACGTACCACTAACTCTGGAAGCTCAATTAGAAGCA
CGTACCCTAATGATGTCGACAAACAACATTCTGTCGCCAGCATCAGGTGACCCAATCATCGTACCTTCTCAGGACGTTGT
ATTAGGTCTGTACTACATGACACGTGAAAAAATTAACGCGAAAGGCGAAGGCATGTACCTTGAAGGTTTTGCTGAAGCTG
AAAAAGCATACCGTACAGGTGTTGCAGAGCTACATGCTCGCGTTAAAGTTCGTATCACTGAAGTTCTTCGTGATGAGAAT
GGTATTGAAACTCGTGAAACTAAACTGGTTGATACGACTGTTGGTCGTGCAATGCTATGGCAAATCGTGCCAGAAGGTCT
TCCTTACAGCATCATTAACCAGAAGTTAGGTAAGAAGCAAATCTCTAACCTACTAAACGAAGCGTACCGTACTCTTGGTC
TTAAAGACACTGTAGTGTTTGCTGACCAAATCATGTACACCGGTTTCGCATACGCAGCATTGTCTGGTGCGTCTGTTGGT
ATCGATGACATGGTTATCCCTGATGCTAAGTATACGAAAGTTGCTGATGCAGAAGAAGAAGTTAAGCAAATTCAAGAACA
GTACCAATCTGGTCTTGTAACTGCGGGCGAACGTTACAACAAAGTTATCGATATCTGGGCGGCAACAAACGAACAAGTTG
CTAAAGAGATGATGGATAACCTGTCTTCAGAAACAGTGCTTAACCGCGATGGTGAAGAAGAGCAACAAGAATCGTTTAAC
AGCGTTTACATGATGGCCGATTCCGGTGCTCGTGGTTCTGCAGCTCAGATTCGTCAGCTAGCTGGTATGCGTGGTCTGAT
GGCTAAACCAGATGGTTCAATCATCGAAACACCGATCACGGCGAACTTCCGTGAAGGTCTAAACGTAAACCAATACTTCA
TCTCAACGCACGGTGCGCGTAAAGGTCTTGCCGATACAGCACTTAAAACTGCGAACTCAGGTTACCTGACTCGTCGTTTA
GTAGACGTTGCACAAGATGTAGTTGTTCACTTAGATGACTGTGGTACATACGAAGGTGTGACCATGACTCCTCTAATTGA
AGGTGGTGACGTTAAAGAACCTCTACACGAACGTGTTCTAGGTCGTGTGGTTGCTGAAGATGTATTGAAACCAGGTACAG
ATGAAATTCTTCTTCCACGTAACACACTTCTTGATGAGAAGCAGTGTCAAATCGTTGAAGAAAACTCAGTTGACCAAATT
AAAGTACGTTCAGTAGTAAGCTGTGAAGCTGACTTCGGTTGTTGTGCAAACTGTTACGGTCGTGACCTAGCTCGTGGTCA
TATGGTTAACCAAGGTGAGTCAGTTGGTGTTATCGCTGCTCAATCAATCGGTGAACCTGGTACACAGCTAACGATGCGTA
CGTTCCACATCGGTGGTGCGGCATCTACAGCGGCAGCAGACAACAGCATTCAAGTTAAGACGACTGGTTCGATCAAACTT
CATAATGCTAAGCACGTAACAAATGGCGAAGGTAACTTAGTTATTACGTCTCGTGCTTCTGAATTAACAGTTATTGATGA
GCATGGCCGTACAAAAGAAAGCTACAAACTATCTTACGGTACTATCTTAACTAAGAAAGATGGTGATGCAGTTAACCAAG
GCGACAAGATCGCATCTTGGGATCCGCATACAATGCCAATCATCACTGAAGTACAAGGTCAAGTTCAATTCGTTGATATG
ATTGATGGTGTTACGATCACAACTCAAACTGATGAGCTAACTGGTCTATCTTCAATCGTTGTTCTTGATGCGGCTGAGCG
TGCTTCTGCTGGTAAAGACATGCGTCCAACAGTGAAACTTGTTGATGCGAATGGTAACGACATCATGATCCCTGGTACTG
AAATGCCAGCTCAATACTTCCTACCTGGTAAGGCGATTGTTAACCTTGCTGATGGTGGTAACGTAGGTATTGGTGAAACG
TTAGCTCGTATTCCTCAAGCTTCAAGCGGTACTAAAGATATCACCGGTGGTCTACCACGCGTTGCGGACTTATTTGAAGC
TCGTAAGCCTAAAGAGCCAGCAATTCTTGCTGAGCACGCAGGTATTGTTGCGTTTGGTAAAGAGACTAAAGGTAAGGTTC
GCTTATTGATCACTCGTGACGATAACGGCGAAGTTTATGAAGAAATGATTCATAAACACCGTCAACTTAACATCTTTGAA
GGTGATAAAGTTGAACGTGGTGACGTTATCTCTGATGGTCCAGAAACTCCACATGATATCCTACGTTTACGTGGTATTCA
TGCAGTTACTGAATACATCACTAACGAAGTTCAAGAAGTTTACCGTTTACAAGGCGTTAAGATTAACGATAAGCACATTG
AAACTATCGTTCGTCAAATGCTACGTAAGTGTACGATTACACATTCTGGTGATTCTACTTTCCTTGAAGGTGAGCAACTA
GAATTCGCTAACGTAACGATTGCAAACCGTCAGCTTGAAGCTGAAGGCAAGCAACCTGCACGTTTCGAGCGTGATCTACT
AGGTATTACTAAAGCGTCTCTTGCTACTGAGTCGTTCATCTCTGCTGCATCGTTCCAAGAAACGACGCGCGTACTTACTG
AAGCAGCGGTTTCTGGTAAGCGTGATGAACTACGTGGTCTGAAAGAAAACGTAATCGTTGGTCGTCTAATTCCAGCGGGT
ACAGGTTTCGCATACCACCAAGAACGTCAAAAGCAAAAAGCTGTGGAGCAAGAAGGTCCATCAGCTGAGCAAGCGACTGA
TAACTTAGCGGCACTATTAAATGCAGGTTTCTCTTCTGAAGAGTAA

Upstream 100 bases:

>100_bases
TCAACATCGAGTTAGAAGACGAAGAATAATCTCATTGAGATTGTCCGGTAGAATATAAGGCGCTCGCCGAGCGCCTTTTT
TCTCCTTACAGGAGCCGAAT

Downstream 100 bases:

>100_bases
TTGATTTAATAAACGCAAATAAAAGCCCTGCAGAGATGCAGGGCTTTTTTATTTAAGTGATAAATTTATAGTTGAGTAAT
TACAACAGCATTGTAACTAC

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1401; Mature: 1401

Protein sequence:

>1401_residues
MKDLLKFLKAQHKTEEFDAIKIGLASPDQIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSLPSRIGLLMDIPLRDIERVLYFESYVVTEPGMTDLERSQLL
SEEEYLDKLEEFGDEFTAKMGAEAIKDLLASMDMQAEIEDMREELETTNSETKRKKVTKRLKLVEAFVQSGNNPEWMILT
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYSKLEGRGLATTIKAAKKM
VEREEAIVWDILDDVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTREKINAKGEGMYLEGFAEAEKAYRTGVAELHARVKVRITEVLRDEN
GIETRETKLVDTTVGRAMLWQIVPEGLPYSIINQKLGKKQISNLLNEAYRTLGLKDTVVFADQIMYTGFAYAALSGASVG
IDDMVIPDAKYTKVADAEEEVKQIQEQYQSGLVTAGERYNKVIDIWAATNEQVAKEMMDNLSSETVLNRDGEEEQQESFN
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVNQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDVVVHLDDCGTYEGVTMTPLIEGGDVKEPLHERVLGRVVAEDVLKPGTDEILLPRNTLLDEKQCQIVEENSVDQI
KVRSVVSCEADFGCCANCYGRDLARGHMVNQGESVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAADNSIQVKTTGSIKL
HNAKHVTNGEGNLVITSRASELTVIDEHGRTKESYKLSYGTILTKKDGDAVNQGDKIASWDPHTMPIITEVQGQVQFVDM
IDGVTITTQTDELTGLSSIVVLDAAERASAGKDMRPTVKLVDANGNDIMIPGTEMPAQYFLPGKAIVNLADGGNVGIGET
LARIPQASSGTKDITGGLPRVADLFEARKPKEPAILAEHAGIVAFGKETKGKVRLLITRDDNGEVYEEMIHKHRQLNIFE
GDKVERGDVISDGPETPHDILRLRGIHAVTEYITNEVQEVYRLQGVKINDKHIETIVRQMLRKCTITHSGDSTFLEGEQL
EFANVTIANRQLEAEGKQPARFERDLLGITKASLATESFISAASFQETTRVLTEAAVSGKRDELRGLKENVIVGRLIPAG
TGFAYHQERQKQKAVEQEGPSAEQATDNLAALLNAGFSSEE

Sequences:

>Translated_1401_residues
MKDLLKFLKAQHKTEEFDAIKIGLASPDQIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSLPSRIGLLMDIPLRDIERVLYFESYVVTEPGMTDLERSQLL
SEEEYLDKLEEFGDEFTAKMGAEAIKDLLASMDMQAEIEDMREELETTNSETKRKKVTKRLKLVEAFVQSGNNPEWMILT
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYSKLEGRGLATTIKAAKKM
VEREEAIVWDILDDVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTREKINAKGEGMYLEGFAEAEKAYRTGVAELHARVKVRITEVLRDEN
GIETRETKLVDTTVGRAMLWQIVPEGLPYSIINQKLGKKQISNLLNEAYRTLGLKDTVVFADQIMYTGFAYAALSGASVG
IDDMVIPDAKYTKVADAEEEVKQIQEQYQSGLVTAGERYNKVIDIWAATNEQVAKEMMDNLSSETVLNRDGEEEQQESFN
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVNQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDVVVHLDDCGTYEGVTMTPLIEGGDVKEPLHERVLGRVVAEDVLKPGTDEILLPRNTLLDEKQCQIVEENSVDQI
KVRSVVSCEADFGCCANCYGRDLARGHMVNQGESVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAADNSIQVKTTGSIKL
HNAKHVTNGEGNLVITSRASELTVIDEHGRTKESYKLSYGTILTKKDGDAVNQGDKIASWDPHTMPIITEVQGQVQFVDM
IDGVTITTQTDELTGLSSIVVLDAAERASAGKDMRPTVKLVDANGNDIMIPGTEMPAQYFLPGKAIVNLADGGNVGIGET
LARIPQASSGTKDITGGLPRVADLFEARKPKEPAILAEHAGIVAFGKETKGKVRLLITRDDNGEVYEEMIHKHRQLNIFE
GDKVERGDVISDGPETPHDILRLRGIHAVTEYITNEVQEVYRLQGVKINDKHIETIVRQMLRKCTITHSGDSTFLEGEQL
EFANVTIANRQLEAEGKQPARFERDLLGITKASLATESFISAASFQETTRVLTEAAVSGKRDELRGLKENVIVGRLIPAG
TGFAYHQERQKQKAVEQEGPSAEQATDNLAALLNAGFSSEE
>Mature_1401_residues
MKDLLKFLKAQHKTEEFDAIKIGLASPDQIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSLPSRIGLLMDIPLRDIERVLYFESYVVTEPGMTDLERSQLL
SEEEYLDKLEEFGDEFTAKMGAEAIKDLLASMDMQAEIEDMREELETTNSETKRKKVTKRLKLVEAFVQSGNNPEWMILT
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYSKLEGRGLATTIKAAKKM
VEREEAIVWDILDDVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTREKINAKGEGMYLEGFAEAEKAYRTGVAELHARVKVRITEVLRDEN
GIETRETKLVDTTVGRAMLWQIVPEGLPYSIINQKLGKKQISNLLNEAYRTLGLKDTVVFADQIMYTGFAYAALSGASVG
IDDMVIPDAKYTKVADAEEEVKQIQEQYQSGLVTAGERYNKVIDIWAATNEQVAKEMMDNLSSETVLNRDGEEEQQESFN
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVNQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDVVVHLDDCGTYEGVTMTPLIEGGDVKEPLHERVLGRVVAEDVLKPGTDEILLPRNTLLDEKQCQIVEENSVDQI
KVRSVVSCEADFGCCANCYGRDLARGHMVNQGESVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAADNSIQVKTTGSIKL
HNAKHVTNGEGNLVITSRASELTVIDEHGRTKESYKLSYGTILTKKDGDAVNQGDKIASWDPHTMPIITEVQGQVQFVDM
IDGVTITTQTDELTGLSSIVVLDAAERASAGKDMRPTVKLVDANGNDIMIPGTEMPAQYFLPGKAIVNLADGGNVGIGET
LARIPQASSGTKDITGGLPRVADLFEARKPKEPAILAEHAGIVAFGKETKGKVRLLITRDDNGEVYEEMIHKHRQLNIFE
GDKVERGDVISDGPETPHDILRLRGIHAVTEYITNEVQEVYRLQGVKINDKHIETIVRQMLRKCTITHSGDSTFLEGEQL
EFANVTIANRQLEAEGKQPARFERDLLGITKASLATESFISAASFQETTRVLTEAAVSGKRDELRGLKENVIVGRLIPAG
TGFAYHQERQKQKAVEQEGPSAEQATDNLAALLNAGFSSEE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=905, Percent_Identity=26.1878453038674, Blast_Score=208, Evalue=2e-53,
Organism=Homo sapiens, GI39725938, Length=307, Percent_Identity=31.5960912052117, Blast_Score=130, Evalue=6e-30,
Organism=Homo sapiens, GI103471997, Length=596, Percent_Identity=25.6711409395973, Blast_Score=120, Evalue=1e-26,
Organism=Escherichia coli, GI2367335, Length=1406, Percent_Identity=81.5078236130868, Blast_Score=2362, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=905, Percent_Identity=25.9668508287293, Blast_Score=193, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI25145495, Length=719, Percent_Identity=26.5646731571627, Blast_Score=187, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6320061, Length=659, Percent_Identity=26.4036418816388, Blast_Score=167, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6324690, Length=344, Percent_Identity=31.6860465116279, Blast_Score=145, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6324917, Length=282, Percent_Identity=27.6595744680851, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI17530899, Length=900, Percent_Identity=24.7777777777778, Blast_Score=195, Evalue=2e-49,
Organism=Drosophila melanogaster, GI281360912, Length=511, Percent_Identity=24.6575342465753, Blast_Score=135, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_VIBF1 (Q5E239)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_205795.2
- HSSP:   Q9KWU6
- ProteinModelPortal:   Q5E239
- STRING:   Q5E239
- GeneID:   3279558
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_2412
- NMPDR:   fig|312309.3.peg.2412
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   HVWYLKG
- ProtClustDB:   PRK00566
- BioCyc:   VFIS312309:VF2412-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 155113; Mature: 155113

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLLKFLKAQHKTEEFDAIKIGLASPDQIRSWSFGEVKKPETINYRTFKPERDGLFCAR
CHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
PSRIGLLMDIPLRDIERVLYFESYVVTEPGMTDLERSQLLSEEEYLDKLEEFGDEFTAKM
HHHCCEEEECCHHHHHHHHHHHHEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GAEAIKDLLASMDMQAEIEDMREELETTNSETKRKKVTKRLKLVEAFVQSGNNPEWMILT
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
ESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPY
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFIYSKLEGRGLATTIKAAKKMVEREEAIVWDILDDVIREHP
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
EEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEEEEEEEECCCCC
RTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTREKINAKGEGMYLEGFAEAEKAYRTG
EEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHC
VAELHARVKVRITEVLRDENGIETRETKLVDTTVGRAMLWQIVPEGLPYSIINQKLGKKQ
HHHHHHHHHEEHHHHHHCCCCCCHHHHEEHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHH
ISNLLNEAYRTLGLKDTVVFADQIMYTGFAYAALSGASVGIDDMVIPDAKYTKVADAEEE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCHHHH
VKQIQEQYQSGLVTAGERYNKVIDIWAATNEQVAKEMMDNLSSETVLNRDGEEEQQESFN
HHHHHHHHHCCCEECCCCCCEEEEEEECCCHHHHHHHHHCCCCCHHHCCCCCHHHHHCCC
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVNQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHCCCCCCEEEEECCCCC
KGLADTALKTANSGYLTRRLVDVAQDVVVHLDDCGTYEGVTMTPLIEGGDVKEPLHERVL
CCHHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCCCCCHHHHHHHH
GRVVAEDVLKPGTDEILLPRNTLLDEKQCQIVEENSVDQIKVRSVVSCEADFGCCANCYG
HHHHHHHHHCCCCCCEEECCHHHCCCHHHHEECCCCCCCEEHHHHEECCCCCCCHHHHHH
RDLARGHMVNQGESVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAADNSIQVKTTGSIKL
HHHHCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEECCCEEE
HNAKHVTNGEGNLVITSRASELTVIDEHGRTKESYKLSYGTILTKKDGDAVNQGDKIASW
ECCCEEECCCCCEEEEECCCEEEEECCCCCCCHHEEEEECEEEECCCCCCCCCCCCCCCC
DPHTMPIITEVQGQVQFVDMIDGVTITTQTDELTGLSSIVVLDAAERASAGKDMRPTVKL
CCCCCCEEEECCCCEEEEEECCCEEEEECCHHHCCCCEEEEEECHHHHCCCCCCCCEEEE
VDANGNDIMIPGTEMPAQYFLPGKAIVNLADGGNVGIGETLARIPQASSGTKDITGGLPR
EECCCCEEEECCCCCCHHHCCCCHHEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCHH
VADLFEARKPKEPAILAEHAGIVAFGKETKGKVRLLITRDDNGEVYEEMIHKHRQLNIFE
HHHHHHHCCCCCCCEEECCCCEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCEEC
GDKVERGDVISDGPETPHDILRLRGIHAVTEYITNEVQEVYRLQGVKINDKHIETIVRQM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LRKCTITHSGDSTFLEGEQLEFANVTIANRQLEAEGKQPARFERDLLGITKASLATESFI
HHHCCEEECCCCCEECCCCEEEEEEEEECCEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVSGKRDELRGLKENVIVGRLIPAGTGFAYHQERQKQKAVEQEGP
HHHHHHHHHHHHHHHHHCCCHHHHHCHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
SAEQATDNLAALLNAGFSSEE
CHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKDLLKFLKAQHKTEEFDAIKIGLASPDQIRSWSFGEVKKPETINYRTFKPERDGLFCAR
CHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
PSRIGLLMDIPLRDIERVLYFESYVVTEPGMTDLERSQLLSEEEYLDKLEEFGDEFTAKM
HHHCCEEEECCHHHHHHHHHHHHEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GAEAIKDLLASMDMQAEIEDMREELETTNSETKRKKVTKRLKLVEAFVQSGNNPEWMILT
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
ESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPY
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFIYSKLEGRGLATTIKAAKKMVEREEAIVWDILDDVIREHP
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
EEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEEEEEEEECCCCC
RTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTREKINAKGEGMYLEGFAEAEKAYRTG
EEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHC
VAELHARVKVRITEVLRDENGIETRETKLVDTTVGRAMLWQIVPEGLPYSIINQKLGKKQ
HHHHHHHHHEEHHHHHHCCCCCCHHHHEEHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHH
ISNLLNEAYRTLGLKDTVVFADQIMYTGFAYAALSGASVGIDDMVIPDAKYTKVADAEEE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCHHHH
VKQIQEQYQSGLVTAGERYNKVIDIWAATNEQVAKEMMDNLSSETVLNRDGEEEQQESFN
HHHHHHHHHCCCEECCCCCCEEEEEEECCCHHHHHHHHHCCCCCHHHCCCCCHHHHHCCC
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVNQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHCCCCCCEEEEECCCCC
KGLADTALKTANSGYLTRRLVDVAQDVVVHLDDCGTYEGVTMTPLIEGGDVKEPLHERVL
CCHHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCCCCCHHHHHHHH
GRVVAEDVLKPGTDEILLPRNTLLDEKQCQIVEENSVDQIKVRSVVSCEADFGCCANCYG
HHHHHHHHHCCCCCCEEECCHHHCCCHHHHEECCCCCCCEEHHHHEECCCCCCCHHHHHH
RDLARGHMVNQGESVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAADNSIQVKTTGSIKL
HHHHCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEECCCEEE
HNAKHVTNGEGNLVITSRASELTVIDEHGRTKESYKLSYGTILTKKDGDAVNQGDKIASW
ECCCEEECCCCCEEEEECCCEEEEECCCCCCCHHEEEEECEEEECCCCCCCCCCCCCCCC
DPHTMPIITEVQGQVQFVDMIDGVTITTQTDELTGLSSIVVLDAAERASAGKDMRPTVKL
CCCCCCEEEECCCCEEEEEECCCEEEEECCHHHCCCCEEEEEECHHHHCCCCCCCCEEEE
VDANGNDIMIPGTEMPAQYFLPGKAIVNLADGGNVGIGETLARIPQASSGTKDITGGLPR
EECCCCEEEECCCCCCHHHCCCCHHEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCHH
VADLFEARKPKEPAILAEHAGIVAFGKETKGKVRLLITRDDNGEVYEEMIHKHRQLNIFE
HHHHHHHCCCCCCCEEECCCCEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCEEC
GDKVERGDVISDGPETPHDILRLRGIHAVTEYITNEVQEVYRLQGVKINDKHIETIVRQM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LRKCTITHSGDSTFLEGEQLEFANVTIANRQLEAEGKQPARFERDLLGITKASLATESFI
HHHCCEEECCCCCEECCCCEEEEEEEEECCEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVSGKRDELRGLKENVIVGRLIPAGTGFAYHQERQKQKAVEQEGP
HHHHHHHHHHHHHHHHHCCCHHHHHCHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
SAEQATDNLAALLNAGFSSEE
CHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA