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The map label for this gene is glmM [H]

Identifier: 172087666

GI number: 172087666

Start: 517014

End: 518351

Strand: Direct

Name: glmM [H]

Synonym: VF_0481

Alternate gene names: 172087666

Gene position: 517014-518351 (Clockwise)

Preceding gene: 59711087

Following gene: 59711090

Centisome position: 17.84

GC content: 41.55

Gene sequence:

>1338_bases
ATGGCTGAACGTAAATATTTCGGAACTGATGGCGTTCGAGGATTAGTAGGGCAAGCACCTATCACACCTGATTTTGTTAT
GAAGCTTGGCTGGGCGGCAGGACAAGTTTTAGCTAAGCAAGGTACAAAAAAAGTCATTATTGGTAAAGATACGCGTATTT
CTGGTTATATGCTTGAATCAGCATTAGAAGCAGGTTTAGCAGCTGCTGGATTACAAGCTAAATTTACGGGTCCGATGCCA
ACTCCTGCTGTGGCTTACCTTACTCAGACATTTCGTGCAGAAGCAGGTATTGTGATTTCAGCTTCTCATAATCCATACTA
CGATAATGGCATTAAATTCTTCTCATCAGAAGGGACAAAACTTCCGGATGACGTTGAAATGGCGATTGAAGCAGAGCTTG
ATAAGCCAATGACATGTGTTGAATCTGCTTTACTTGGTAAAGCCTCTCGTCTTAATGATGCTGCAGGTCGTTACATTGAA
TTCTGTAAAAGTACCTTCCCTAAAGAATTAAGTCTTGCTGGTTTAAAAATCGTTATCGATTGTGCAAATGGTGCAACGTA
TCATATTGCTCCTAATGTATTTAAAGAGCTAGGTGCAGAGATCATCACAATCGGTTGTGAGCCAAACGGAACCAATATTA
ACCATGAAGTAGGAGCTACTGATGTTCGAGCTCTTCAAGCAAAAGTTGTTGAAGAAAAAGCCGATTTTGGTGTTGCATTT
GATGGTGACGGTGACCGTATCATCATGGTGGATGAATTCGGCGAAAAAGTAGATGGCGACCAGATTGCGTACATCATTGC
TCGTGACGCACTGCGTCGTGGTGAGTTAAAAGGTGGTGTGGTTGGTACATTGATGACGAATATGGGGATGGAGGTTGCTT
TACGTAATCTTGGAATTCCATTTGTTCGTTCAGATGTTGGTGACCGCTATGTGATGGAAAAACTTCTAGAAAACAACTGG
TTAATTGGTGCGGAGAATTCAGGTCACGTTATTCTTTTAGATAAAGTAACGACGGGCGATGCTATTGTTGCAGCGCTTCA
AGTTATTGCGTCGATTGTAGGCAGTAAAATGTCATTAAAAGAATTATGTGATGGCATGACAATGTTCCCACAAATCTTAG
TTAACGTTCGATTTGCTGGTGAGAATGATCCTCTTGAATCAGATGCAGTAAAAGCAGCTCAAGCTGATGTGGAAGCTAAA
TTAGGTGATAATGGTCGTGTATTATTGCGTAAGTCAGGTACAGAGCCTTTAATTCGCGTTATGGTTGAAGGTGAAGATGC
GGAATTAGTGACACAATATGCGCAACAAATTGCGGATGCGGTGAAAGAAAGCTGCTAA

Upstream 100 bases:

>100_bases
GATGGATATCGTAAAGGTTTGCCAAGCAACTTTAGAGCAATCTCCTCATTAAAGAGTTGTTCAATTTAAATAAATTATTA
AAAAAAACATGGAGTACAAC

Downstream 100 bases:

>100_bases
TTTGAGCAATTAAATGAAATTGAACGTTTTTTGTTAATTTTAACTTGTCATAGTAGCCTAGTTTGGTTAATATCCTTCGG
CCTCTTAATTGAGAGGGCGC

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MAERKYFGTDGVRGLVGQAPITPDFVMKLGWAAGQVLAKQGTKKVIIGKDTRISGYMLESALEAGLAAAGLQAKFTGPMP
TPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSSEGTKLPDDVEMAIEAELDKPMTCVESALLGKASRLNDAAGRYIE
FCKSTFPKELSLAGLKIVIDCANGATYHIAPNVFKELGAEIITIGCEPNGTNINHEVGATDVRALQAKVVEEKADFGVAF
DGDGDRIIMVDEFGEKVDGDQIAYIIARDALRRGELKGGVVGTLMTNMGMEVALRNLGIPFVRSDVGDRYVMEKLLENNW
LIGAENSGHVILLDKVTTGDAIVAALQVIASIVGSKMSLKELCDGMTMFPQILVNVRFAGENDPLESDAVKAAQADVEAK
LGDNGRVLLRKSGTEPLIRVMVEGEDAELVTQYAQQIADAVKESC

Sequences:

>Translated_445_residues
MAERKYFGTDGVRGLVGQAPITPDFVMKLGWAAGQVLAKQGTKKVIIGKDTRISGYMLESALEAGLAAAGLQAKFTGPMP
TPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSSEGTKLPDDVEMAIEAELDKPMTCVESALLGKASRLNDAAGRYIE
FCKSTFPKELSLAGLKIVIDCANGATYHIAPNVFKELGAEIITIGCEPNGTNINHEVGATDVRALQAKVVEEKADFGVAF
DGDGDRIIMVDEFGEKVDGDQIAYIIARDALRRGELKGGVVGTLMTNMGMEVALRNLGIPFVRSDVGDRYVMEKLLENNW
LIGAENSGHVILLDKVTTGDAIVAALQVIASIVGSKMSLKELCDGMTMFPQILVNVRFAGENDPLESDAVKAAQADVEAK
LGDNGRVLLRKSGTEPLIRVMVEGEDAELVTQYAQQIADAVKESC
>Mature_444_residues
AERKYFGTDGVRGLVGQAPITPDFVMKLGWAAGQVLAKQGTKKVIIGKDTRISGYMLESALEAGLAAAGLQAKFTGPMPT
PAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSSEGTKLPDDVEMAIEAELDKPMTCVESALLGKASRLNDAAGRYIEF
CKSTFPKELSLAGLKIVIDCANGATYHIAPNVFKELGAEIITIGCEPNGTNINHEVGATDVRALQAKVVEEKADFGVAFD
GDGDRIIMVDEFGEKVDGDQIAYIIARDALRRGELKGGVVGTLMTNMGMEVALRNLGIPFVRSDVGDRYVMEKLLENNWL
IGAENSGHVILLDKVTTGDAIVAALQVIASIVGSKMSLKELCDGMTMFPQILVNVRFAGENDPLESDAVKAAQADVEAKL
GDNGRVLLRKSGTEPLIRVMVEGEDAELVTQYAQQIADAVKESC

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1789566, Length=443, Percent_Identity=76.2979683972912, Blast_Score=682, Evalue=0.0,
Organism=Escherichia coli, GI1788361, Length=450, Percent_Identity=26.4444444444444, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 47630; Mature: 47499

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERKYFGTDGVRGLVGQAPITPDFVMKLGWAAGQVLAKQGTKKVIIGKDTRISGYMLES
CCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
ALEAGLAAAGLQAKFTGPMPTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSSEGTK
HHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCC
LPDDVEMAIEAELDKPMTCVESALLGKASRLNDAAGRYIEFCKSTFPKELSLAGLKIVID
CCCHHHHHEECCCCCCHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEEEE
CANGATYHIAPNVFKELGAEIITIGCEPNGTNINHEVGATDVRALQAKVVEEKADFGVAF
CCCCCEEEECHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
DGDGDRIIMVDEFGEKVDGDQIAYIIARDALRRGELKGGVVGTLMTNMGMEVALRNLGIP
CCCCCEEEEEECCCCCCCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHCCHHHHHHHCCCC
FVRSDVGDRYVMEKLLENNWLIGAENSGHVILLDKVTTGDAIVAALQVIASIVGSKMSLK
HHHHCCCHHHHHHHHHHCCEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHH
ELCDGMTMFPQILVNVRFAGENDPLESDAVKAAQADVEAKLGDNGRVLLRKSGTEPLIRV
HHHCCHHHHHHHHEEEEECCCCCCCCHHHHHHHHHCCCEEECCCCEEEEEECCCCCEEEE
MVEGEDAELVTQYAQQIADAVKESC
EECCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AERKYFGTDGVRGLVGQAPITPDFVMKLGWAAGQVLAKQGTKKVIIGKDTRISGYMLES
CCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
ALEAGLAAAGLQAKFTGPMPTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSSEGTK
HHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCC
LPDDVEMAIEAELDKPMTCVESALLGKASRLNDAAGRYIEFCKSTFPKELSLAGLKIVID
CCCHHHHHEECCCCCCHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEEEE
CANGATYHIAPNVFKELGAEIITIGCEPNGTNINHEVGATDVRALQAKVVEEKADFGVAF
CCCCCEEEECHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
DGDGDRIIMVDEFGEKVDGDQIAYIIARDALRRGELKGGVVGTLMTNMGMEVALRNLGIP
CCCCCEEEEEECCCCCCCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHCCHHHHHHHCCCC
FVRSDVGDRYVMEKLLENNWLIGAENSGHVILLDKVTTGDAIVAALQVIASIVGSKMSLK
HHHHCCCHHHHHHHHHHCCEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHH
ELCDGMTMFPQILVNVRFAGENDPLESDAVKAAQADVEAKLGDNGRVLLRKSGTEPLIRV
HHHCCHHHHHHHHEEEEECCCCCCCCHHHHHHHHHCCCEEECCCCEEEEEECCCCCEEEE
MVEGEDAELVTQYAQQIADAVKESC
EECCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA