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The map label for this gene is yleA [C]

Identifier: 58617513

GI number: 58617513

Start: 1257808

End: 1259025

Strand: Reverse

Name: yleA [C]

Synonym: ERGA_CDS_07860

Alternate gene names: 58617513

Gene position: 1259025-1257808 (Counterclockwise)

Preceding gene: 58617514

Following gene: 58617505

Centisome position: 83.94

GC content: 34.15

Gene sequence:

>1218_bases
ATGAGTGAAGTAATTACTTTTGGGTGCAGATTAAATTTTTATGAAAGTGAAGTTATAAAAAATAATTTAAAAAAAGCAGA
ACTAGATGATGTTATTGTTGTGCATACTTGTGCTGTTACTAGTGAAGCAGAACGTCAAGTAAAAGCCAAAATACGTAAAC
TTTATAATAATAATGCTAATGTTAAAATAATTGTCGCAGGATGTGCTGCTCAATTAAATCCAGAATCATATATGAGTATG
CCAGGAGTAGTTAAGGTTTTAGGGAATGAAGATAAACTGAAATATGAAAGTTATATTACTGCTGATAAAGTTATTGTGGG
GAATATAGGTAATTCAAGAACAGTTATAAAAGATTCAATAAAACAGTTTCCTGGTAAATCTAGAGCATTGATTGAGATAC
AAAATGGGTGTAATCATGAATGTACTTTTTGTGTTATTACTAAAGCAAGAGGTAATAATCGTTCCCTACATATTGAAGAT
ATTATAACTCAAGTAAAAGATTGTGTTAATAATGGATATAATGAAGTTGTTTTTACTGGTGTAGATATTAGTGATTTTGG
TATCGATATCTATGGTCAACGTATGCTTGGTGTTATGATAAAGAGGGTATTAGGAGCTATACCACAGTTACGTAGATTAA
GGTTATCGTCTATAGATGTCGCAGAGATAGAAGATGATCTTATTGATATTATTGGAAATGAACCTAGGTTTATGCCACAT
TTGCATTTAAGCTTGCAATCTGGAAATAATTTAATTCTTAAAAGGATGAAACGTAGACATAATAGAGAACAGGTAGTGGA
ATTTTGTAATAGAGTAAGTGGCATGAGAAAAGACATAGTATTTGGAGCTGATATTATTGTCGGATTTCCAACAGAGACAG
AAGATATGTTTAATGATACTGTTAAATTGATAGAAGAAGCAAATATTTCATATTTGCATATATTTCCATATTCAGCTAGA
GAAGGTACTCCAGCTGCTAGGATGCCTCAGGTTTCACCAGAGGTTATGCCGACTACTACAACATATCCACGCGACATTCT
CGTAAAAACCCTTGAAAATTTTCAACCCACCCCTGCCAAATTCCCTGTCAACTACCGGTCTCCTAACAACCACCTTTCGG
CGCCGCCACCCCATTTCGCTCCTCCTTCACTTCCTCAAACCCAACCATGTCACCTTTCTCTCAAGTCCCTTCCCCCTTTT
TCTTCATACAAAATTTAA

Upstream 100 bases:

>100_bases
CAAACGCAAATAAATAATTTTAATCAAGTTAATTTAAAGTATATGATACTGCTAAACAGTATTTAATTTTATATAAATAA
CTTAATAGTTAGAGAATGTA

Downstream 100 bases:

>100_bases
GAATCTCAAGGTTCATAATTATGTTTGTTATATTATCTAAAAATGCTTTAATGTTTATATTCAGGTAACATACTTGTAAC
TTGTGATTAATACTAAAATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSEVITFGCRLNFYESEVIKNNLKKAELDDVIVVHTCAVTSEAERQVKAKIRKLYNNNANVKIIVAGCAAQLNPESYMSM
PGVVKVLGNEDKLKYESYITADKVIVGNIGNSRTVIKDSIKQFPGKSRALIEIQNGCNHECTFCVITKARGNNRSLHIED
IITQVKDCVNNGYNEVVFTGVDISDFGIDIYGQRMLGVMIKRVLGAIPQLRRLRLSSIDVAEIEDDLIDIIGNEPRFMPH
LHLSLQSGNNLILKRMKRRHNREQVVEFCNRVSGMRKDIVFGADIIVGFPTETEDMFNDTVKLIEEANISYLHIFPYSAR
EGTPAARMPQVSPEVMPTTTTYPRDILVKTLENFQPTPAKFPVNYRSPNNHLSAPPPHFAPPSLPQTQPCHLSLKSLPPF
SSYKI

Sequences:

>Translated_405_residues
MSEVITFGCRLNFYESEVIKNNLKKAELDDVIVVHTCAVTSEAERQVKAKIRKLYNNNANVKIIVAGCAAQLNPESYMSM
PGVVKVLGNEDKLKYESYITADKVIVGNIGNSRTVIKDSIKQFPGKSRALIEIQNGCNHECTFCVITKARGNNRSLHIED
IITQVKDCVNNGYNEVVFTGVDISDFGIDIYGQRMLGVMIKRVLGAIPQLRRLRLSSIDVAEIEDDLIDIIGNEPRFMPH
LHLSLQSGNNLILKRMKRRHNREQVVEFCNRVSGMRKDIVFGADIIVGFPTETEDMFNDTVKLIEEANISYLHIFPYSAR
EGTPAARMPQVSPEVMPTTTTYPRDILVKTLENFQPTPAKFPVNYRSPNNHLSAPPPHFAPPSLPQTQPCHLSLKSLPPF
SSYKI
>Mature_404_residues
SEVITFGCRLNFYESEVIKNNLKKAELDDVIVVHTCAVTSEAERQVKAKIRKLYNNNANVKIIVAGCAAQLNPESYMSMP
GVVKVLGNEDKLKYESYITADKVIVGNIGNSRTVIKDSIKQFPGKSRALIEIQNGCNHECTFCVITKARGNNRSLHIEDI
ITQVKDCVNNGYNEVVFTGVDISDFGIDIYGQRMLGVMIKRVLGAIPQLRRLRLSSIDVAEIEDDLIDIIGNEPRFMPHL
HLSLQSGNNLILKRMKRRHNREQVVEFCNRVSGMRKDIVFGADIIVGFPTETEDMFNDTVKLIEEANISYLHIFPYSARE
GTPAARMPQVSPEVMPTTTTYPRDILVKTLENFQPTPAKFPVNYRSPNNHLSAPPPHFAPPSLPQTQPCHLSLKSLPPFS
SYKI

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=361, Percent_Identity=29.0858725761773, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI28872782, Length=365, Percent_Identity=23.2876712328767, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI28872784, Length=365, Percent_Identity=23.2876712328767, Blast_Score=109, Evalue=4e-24,
Organism=Escherichia coli, GI1786882, Length=347, Percent_Identity=28.5302593659942, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787057, Length=348, Percent_Identity=27.0114942528736, Blast_Score=115, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17553146, Length=363, Percent_Identity=24.7933884297521, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71996771, Length=205, Percent_Identity=29.2682926829268, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21356207, Length=369, Percent_Identity=26.5582655826558, Blast_Score=138, Evalue=6e-33,
Organism=Drosophila melanogaster, GI19922432, Length=367, Percent_Identity=28.0653950953678, Blast_Score=116, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 45488; Mature: 45357

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVITFGCRLNFYESEVIKNNLKKAELDDVIVVHTCAVTSEAERQVKAKIRKLYNNNAN
CCCEEEEEEEECHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCC
VKIIVAGCAAQLNPESYMSMPGVVKVLGNEDKLKYESYITADKVIVGNIGNSRTVIKDSI
EEEEEEECCCCCCHHHHHCCCCEEEEECCCCCEEHHHHCCCCEEEEECCCCCCHHHHHHH
KQFPGKSRALIEIQNGCNHECTFCVITKARGNNRSLHIEDIITQVKDCVNNGYNEVVFTG
HHCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCEEHHHHHHHHHHHHHCCCCEEEEEE
VDISDFGIDIYGQRMLGVMIKRVLGAIPQLRRLRLSSIDVAEIEDDLIDIIGNEPRFMPH
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEE
LHLSLQSGNNLILKRMKRRHNREQVVEFCNRVSGMRKDIVFGADIIVGFPTETEDMFNDT
EEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHEEEECEEEEECCCCCHHHHHHH
VKLIEEANISYLHIFPYSAREGTPAARMPQVSPEVMPTTTTYPRDILVKTLENFQPTPAK
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
FPVNYRSPNNHLSAPPPHFAPPSLPQTQPCHLSLKSLPPFSSYKI
CCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCC
>Mature Secondary Structure 
SEVITFGCRLNFYESEVIKNNLKKAELDDVIVVHTCAVTSEAERQVKAKIRKLYNNNAN
CCEEEEEEEECHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCC
VKIIVAGCAAQLNPESYMSMPGVVKVLGNEDKLKYESYITADKVIVGNIGNSRTVIKDSI
EEEEEEECCCCCCHHHHHCCCCEEEEECCCCCEEHHHHCCCCEEEEECCCCCCHHHHHHH
KQFPGKSRALIEIQNGCNHECTFCVITKARGNNRSLHIEDIITQVKDCVNNGYNEVVFTG
HHCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCEEHHHHHHHHHHHHHCCCCEEEEEE
VDISDFGIDIYGQRMLGVMIKRVLGAIPQLRRLRLSSIDVAEIEDDLIDIIGNEPRFMPH
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEE
LHLSLQSGNNLILKRMKRRHNREQVVEFCNRVSGMRKDIVFGADIIVGFPTETEDMFNDT
EEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHEEEECEEEEECCCCCHHHHHHH
VKLIEEANISYLHIFPYSAREGTPAARMPQVSPEVMPTTTTYPRDILVKTLENFQPTPAK
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
FPVNYRSPNNHLSAPPPHFAPPSLPQTQPCHLSLKSLPPFSSYKI
CCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]