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The map label for this gene is fabD [H]

Identifier: 58617505

GI number: 58617505

Start: 1242570

End: 1243532

Strand: Reverse

Name: fabD [H]

Synonym: ERGA_CDS_07780

Alternate gene names: 58617505

Gene position: 1243532-1242570 (Counterclockwise)

Preceding gene: 58617513

Following gene: 58617504

Centisome position: 82.91

GC content: 37.18

Gene sequence:

>963_bases
ATGATTTTGATGTTTCCTGGGCAAGGGTCTCAATTTGTATCTATGGGAAAAAACATATACGATAACTTTGCTGTTGCGCG
ATATGTTTTCCATGAGGTGGATGATATCCTTAACAAAAAGTTATCTAAGATAATGTTTGAAGGTTCAATTGAAGAATTAA
CTTCAACAGATAATGCTCAGCTAGCCCTTATGGTGGCTTCTATTGCTACATTGCGTGCTATAGAATATGTACTAGGGACT
CCGCTACATTTATTTAGGCAGATAAAGTATATGGCTGGACATTCCTTAGGGGAATGTGTAGCACTATGTGCATCTGGGGC
ATTGACGTTATTTGAAGTGACGCAACTCTTACTTGTAAGAAGTCAGGCTATGTATGATGCAGTCCCTTTGGGATATGGGG
GAATGTATGCATTAGTAGGTGGTACCTTAGAAGATGTGGAGAAGGTAGTAGCAGCTGCTCAAGAATATGGAATATGTGAA
ATAGCAAATGATAATTGTGAAGGGCAGGTTGTAGTTAGTGGTGTAAATGAAGTACTCCAACAACTACCTGATTTAATTAA
AGGTACTAATATAAAAAAAGCTATAAAATTACAGGTAAGTGGGCCTTTTCACTCATCACTTATGAGTTCTGCCTGTGATA
AGCTACAACAGTTTGTTGAAGGTATTGAAATAAAAATGCCATTAGTAGACATCGTATCGAATGTATCTGCACGAGAGTAT
ACTGATTGTTTAATGATCAAGAATCTAATAGCTAAACAAGTAATTAGTAAAGTACGATGGCGTGAGAGCATCTTATATAT
GATAAAACAAGGATGTACAAACTTTGTTGAGGTTGGACCTGGTACAGTGTTGTCAAGTTTAATGAAGAGGATTCATACAG
GTGTCACTACAGTTAGTATTAATACTGCTGATTCTATAGATCTATTAATGCGGCATCTTGCAGCGGATTGTGTTGGGGCA
TAA

Upstream 100 bases:

>100_bases
TCTGTCAATGATATTATTTATCATAGTACAAATTCATTTTGACTAATTAATAATAACAGAGTACTATAATAAAGAACAAT
AACCAGAATGCTTTAAATAG

Downstream 100 bases:

>100_bases
ATTTCTGACTGATATAAAGATTTACTTCTGTTAATCTGGATTTATCTAAGTTACATCTCTGTTTTTTTATGCACTTTTGG
GTTACTGTGGTTCATATATT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MILMFPGQGSQFVSMGKNIYDNFAVARYVFHEVDDILNKKLSKIMFEGSIEELTSTDNAQLALMVASIATLRAIEYVLGT
PLHLFRQIKYMAGHSLGECVALCASGALTLFEVTQLLLVRSQAMYDAVPLGYGGMYALVGGTLEDVEKVVAAAQEYGICE
IANDNCEGQVVVSGVNEVLQQLPDLIKGTNIKKAIKLQVSGPFHSSLMSSACDKLQQFVEGIEIKMPLVDIVSNVSAREY
TDCLMIKNLIAKQVISKVRWRESILYMIKQGCTNFVEVGPGTVLSSLMKRIHTGVTTVSINTADSIDLLMRHLAADCVGA

Sequences:

>Translated_320_residues
MILMFPGQGSQFVSMGKNIYDNFAVARYVFHEVDDILNKKLSKIMFEGSIEELTSTDNAQLALMVASIATLRAIEYVLGT
PLHLFRQIKYMAGHSLGECVALCASGALTLFEVTQLLLVRSQAMYDAVPLGYGGMYALVGGTLEDVEKVVAAAQEYGICE
IANDNCEGQVVVSGVNEVLQQLPDLIKGTNIKKAIKLQVSGPFHSSLMSSACDKLQQFVEGIEIKMPLVDIVSNVSAREY
TDCLMIKNLIAKQVISKVRWRESILYMIKQGCTNFVEVGPGTVLSSLMKRIHTGVTTVSINTADSIDLLMRHLAADCVGA
>Mature_320_residues
MILMFPGQGSQFVSMGKNIYDNFAVARYVFHEVDDILNKKLSKIMFEGSIEELTSTDNAQLALMVASIATLRAIEYVLGT
PLHLFRQIKYMAGHSLGECVALCASGALTLFEVTQLLLVRSQAMYDAVPLGYGGMYALVGGTLEDVEKVVAAAQEYGICE
IANDNCEGQVVVSGVNEVLQQLPDLIKGTNIKKAIKLQVSGPFHSSLMSSACDKLQQFVEGIEIKMPLVDIVSNVSAREY
TDCLMIKNLIAKQVISKVRWRESILYMIKQGCTNFVEVGPGTVLSSLMKRIHTGVTTVSINTADSIDLLMRHLAADCVGA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=303, Percent_Identity=31.023102310231, Blast_Score=135, Evalue=4e-32,
Organism=Escherichia coli, GI1787334, Length=304, Percent_Identity=33.5526315789474, Blast_Score=160, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=28.7162162162162, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=302, Percent_Identity=25.8278145695364, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24665753, Length=323, Percent_Identity=30.9597523219814, Blast_Score=144, Evalue=6e-35,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34869; Mature: 34869

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILMFPGQGSQFVSMGKNIYDNFAVARYVFHEVDDILNKKLSKIMFEGSIEELTSTDNAQ
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCH
LALMVASIATLRAIEYVLGTPLHLFRQIKYMAGHSLGECVALCASGALTLFEVTQLLLVR
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHH
SQAMYDAVPLGYGGMYALVGGTLEDVEKVVAAAQEYGICEIANDNCEGQVVVSGVNEVLQ
HHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCCEEEHHHHHHHHH
QLPDLIKGTNIKKAIKLQVSGPFHSSLMSSACDKLQQFVEGIEIKMPLVDIVSNVSAREY
HHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEECCCHHHHHCCCCHHHH
TDCLMIKNLIAKQVISKVRWRESILYMIKQGCTNFVEVGPGTVLSSLMKRIHTGVTTVSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHCCCEEEEE
NTADSIDLLMRHLAADCVGA
CCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILMFPGQGSQFVSMGKNIYDNFAVARYVFHEVDDILNKKLSKIMFEGSIEELTSTDNAQ
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCH
LALMVASIATLRAIEYVLGTPLHLFRQIKYMAGHSLGECVALCASGALTLFEVTQLLLVR
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHH
SQAMYDAVPLGYGGMYALVGGTLEDVEKVVAAAQEYGICEIANDNCEGQVVVSGVNEVLQ
HHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCCEEEHHHHHHHHH
QLPDLIKGTNIKKAIKLQVSGPFHSSLMSSACDKLQQFVEGIEIKMPLVDIVSNVSAREY
HHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEECCCHHHHHCCCCHHHH
TDCLMIKNLIAKQVISKVRWRESILYMIKQGCTNFVEVGPGTVLSSLMKRIHTGVTTVSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHCCCEEEEE
NTADSIDLLMRHLAADCVGA
CCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]