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The map label for this gene is frr

Identifier: 58617480

GI number: 58617480

Start: 1198680

End: 1199237

Strand: Reverse

Name: frr

Synonym: ERGA_CDS_07530

Alternate gene names: 58617480

Gene position: 1199237-1198680 (Counterclockwise)

Preceding gene: 58617481

Following gene: 58617479

Centisome position: 79.95

GC content: 30.65

Gene sequence:

>558_bases
ATGATTAATACAATAAAGCAAGATGCTAAGAATAGAATGGAGAAGACATTATCGGTATATTTAAGTGATGTTGATGGTAT
TAGAACTGGGAGAGCTAGAGCTTCAGTTTTAGATGGGATTGTTGTTGAAACTTATGGTGGACGTGTTAAACTTAATACGA
TCTCTAGTATATCTGTATCCGATAATAAAACTTTATTAGTTAAGGTATGGGACATCAATAATGTAGGTGCTATAAAAACA
GCAATTATAAATTCAAATTTAGGATTTGGGTTCTCTTGTGAAGGTGCCGTTATAAGGTTGACTGTTCCGGATATGACACA
AGATATGAGAAAGAATCTAGTAAAGTTGTTAGGTAAAATTTCGGAAGATTGTAGAATTTCTATCAGGAATATACGGAGAG
ATATTATGGATAAGCTTAAGATAATGCAAGATAATAAAGATATTTCCGAAGATGATTTACGTATAGCTGGAGTAGAAATA
CAAAAAATTACTGATGAAATTATAAAGAAGATAAATGATACTTTTTTAGCAAAAGAGAAAGAACTGTTACATGTATAA

Upstream 100 bases:

>100_bases
ATCTAGGTAAACGTGGTGCACTTGCTGATATAATCTGTGGTGGTGGTTTGTATACAACAATATATAATTAAGATTTAATA
GAAATAGTTGGTATAATAAG

Downstream 100 bases:

>100_bases
AATGAGTACATGGTTTAGTTTATGTAATACTTAATTTTAATTAGGTACTTGCTTGTTAATAGTATTATATTATGTTTATG
ATGCTGGGTAAATGATTGAG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MINTIKQDAKNRMEKTLSVYLSDVDGIRTGRARASVLDGIVVETYGGRVKLNTISSISVSDNKTLLVKVWDINNVGAIKT
AIINSNLGFGFSCEGAVIRLTVPDMTQDMRKNLVKLLGKISEDCRISIRNIRRDIMDKLKIMQDNKDISEDDLRIAGVEI
QKITDEIIKKINDTFLAKEKELLHV

Sequences:

>Translated_185_residues
MINTIKQDAKNRMEKTLSVYLSDVDGIRTGRARASVLDGIVVETYGGRVKLNTISSISVSDNKTLLVKVWDINNVGAIKT
AIINSNLGFGFSCEGAVIRLTVPDMTQDMRKNLVKLLGKISEDCRISIRNIRRDIMDKLKIMQDNKDISEDDLRIAGVEI
QKITDEIIKKINDTFLAKEKELLHV
>Mature_185_residues
MINTIKQDAKNRMEKTLSVYLSDVDGIRTGRARASVLDGIVVETYGGRVKLNTISSISVSDNKTLLVKVWDINNVGAIKT
AIINSNLGFGFSCEGAVIRLTVPDMTQDMRKNLVKLLGKISEDCRISIRNIRRDIMDKLKIMQDNKDISEDDLRIAGVEI
QKITDEIIKKINDTFLAKEKELLHV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI291042689, Length=163, Percent_Identity=33.1288343558282, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI20270317, Length=155, Percent_Identity=32.9032258064516, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=41.304347826087, Blast_Score=150, Evalue=3e-38,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_EHRRG (Q5FG66)

Other databases:

- EMBL:   CR925677
- RefSeq:   YP_196679.1
- ProteinModelPortal:   Q5FG66
- SMR:   Q5FG66
- STRING:   Q5FG66
- GeneID:   3268393
- GenomeReviews:   CR925677_GR
- KEGG:   erg:ERGA_CDS_07530
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   ERUM302409:ERGA_CDS_07530-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20749; Mature: 20749

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINTIKQDAKNRMEKTLSVYLSDVDGIRTGRARASVLDGIVVETYGGRVKLNTISSISVS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCEEEEECCCEEEEEEEEEEEEC
DNKTLLVKVWDINNVGAIKTAIINSNLGFGFSCEGAVIRLTVPDMTQDMRKNLVKLLGKI
CCCEEEEEEECCCCCCHHEEEEEECCCCCCEECCCEEEEEECCHHHHHHHHHHHHHHHHC
SEDCRISIRNIRRDIMDKLKIMQDNKDISEDDLRIAGVEIQKITDEIIKKINDTFLAKEK
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCH
ELLHV
HHCCC
>Mature Secondary Structure
MINTIKQDAKNRMEKTLSVYLSDVDGIRTGRARASVLDGIVVETYGGRVKLNTISSISVS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCEEEEECCCEEEEEEEEEEEEC
DNKTLLVKVWDINNVGAIKTAIINSNLGFGFSCEGAVIRLTVPDMTQDMRKNLVKLLGKI
CCCEEEEEEECCCCCCHHEEEEEECCCCCCEECCCEEEEEECCHHHHHHHHHHHHHHHHC
SEDCRISIRNIRRDIMDKLKIMQDNKDISEDDLRIAGVEIQKITDEIIKKINDTFLAKEK
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCH
ELLHV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA