Click here to switch to the map view.

The map label for this gene is argS [H]

Identifier: 58617231

GI number: 58617231

Start: 811663

End: 813468

Strand: Reverse

Name: argS [H]

Synonym: ERGA_CDS_05040

Alternate gene names: 58617231

Gene position: 813468-811663 (Counterclockwise)

Preceding gene: 58617235

Following gene: 161986610

Centisome position: 54.23

GC content: 29.29

Gene sequence:

>1806_bases
TTGTTACTGCTGTTTACTTTTAATATTGCTAAAAACCTGTATAATAGCAAAATTATAAAAGAATTACTGAATATAATGAG
TGTAGCTTGTACCATTAGACGTCATATAATAGAAAAATTACATGTATTAAACATTGATAACTTTGTAGTAACAAATGAGT
CAATATTAGCTAAGTTAATAGTTGATTATCCTAATAATCCTGACCATGGTGATTTATATACTAATGCAGCTTTAATTTTG
AGTAAGTATATTAAAAAGAATCCTATGGATATTGCAAAAATCTTAGTGGATGAATTTTCTAGTATTAAAGAAATATCTGA
TATTAATGTTGTAAAACCTGGTTTTATTAATTTTAATATTTCTCTTGATGTGTGGTATGAAATTATAATTTCTATTAACA
GATTAAAAGAGAAGTTTGGTCATGTTAATTTTGGTAATGGTAAGAGAGTAAATATAGAATTTGTATCTGCTAATCCAACC
GGACCAATGCATATCGGTCATGCGCGTGGTGCTATATTTGGTGATGTACTTGCTAATTTATTAGAAAGAGTAGGATATGA
GGTTGTTAGGGAATATTATATTAATGATGCAGGTGCACAAGTAGATGTATTAGTTGAATCAGTATATTTAAGATATAAAG
AAGTTTTAGGTGAAAATATTGTAATAGGGAGTGGTTTATATCCTGGCTTATATTTGAAAGATATAGGAAAGTTGTTGTAT
CAAGAATATGGTAGTGGTCTACTTGGAATGGATTATAGTCAGAGAAGAAGAATTATACGTGATGTTTCTTTGATGTATCT
TATGAAGCTTATAAAAGAAGATCTTGCATTGTTAGGTATCAAACATGATATTTTTACGTCAGAATCACAATTACAAAAAG
ATAATATTGTACAAAAATGTGTAGAGCTTTTGCAAGAAAAGCAGTTGATATATTATGGTACTTTAGATCAACCTAAAGGT
ACAGAAGGTATAAATTGGAAACCTAGAACTCAGATGTTATTTAAGTCTACTGATTTTGGTGATGATGTAGATAGAGCTTT
ACAAAAAGCTGATGGTAGTTGGACGTATTTTGCAAATGATATAGCATATCATTTTTATAAGATTTCACGTGGTTTTCAAC
ATATGATATTGGAACTTGGTTCTGATCATATTGGGTATGTAAAAAGATTAAAAGCCGCTGTAAAAGCACTAAGTGATGGT
AATGCAACGATTGATATAAAGCTACATAGTATTGTTAATTTTCTTGATAATGGAGCTCAGGTTAAAATGTCAAAAAGATC
TGGCGAGTTTCTAACTATTAAGGATGTTATAGAAAAGGTAGGAAAGGATGTAGTTAGATTTATAATGTTAACTCGTAAAA
GTGATGTGGTTTTGGATTTTGATTTTGCAAAAGTAGTGGAACAGTCTAAAAATAATCCTGTATTTTATGTACAGTATGCA
CATGCTCGTGTTCATTCACTTATACGTAATGCACCAAAAATTCTAGAAATAGAACTTGTAGATTTTTCTGTGTTATCTTC
AAAGGAAGAAATTTTATTAATTAAGCTATTAGCAAAATGGCAAGATATAGTTGAAATATCAGCAAAAACTGCAGAACCAC
ATCGTATAACATTCTATTTAATAGAAGTTGCTGAAGCGTTTCATGCATTATGGGGTTATGGTAATAAGAGTACAGATATG
CGTTTTATTGTAGATAATAATATAAATCTCACATCTGCCAGAATATATTTAGCTAAATCTGTTGGATATGTTATTGCAAG
TGGTTTAACAATATTCTCTATTGTACCATTGACAGAAATGAAATAA

Upstream 100 bases:

>100_bases
TTAAATGGATTAGATTAGTTAAATAGTTTTCTTAAAAGGATCTCTATCATAACATTTTGTGTTTTTTGATATTTTTTATA
TGTGTTTACTTTTGTAAGTA

Downstream 100 bases:

>100_bases
CTATACAAAAATATTAAGATATCATTAGTGTTTTATGTAAGTTTTTACGTACATTTATTGCTATAAATAATGTATTTTTT
ACTTGATCTTAAGGCAAGAT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MLLLFTFNIAKNLYNSKIIKELLNIMSVACTIRRHIIEKLHVLNIDNFVVTNESILAKLIVDYPNNPDHGDLYTNAALIL
SKYIKKNPMDIAKILVDEFSSIKEISDINVVKPGFINFNISLDVWYEIIISINRLKEKFGHVNFGNGKRVNIEFVSANPT
GPMHIGHARGAIFGDVLANLLERVGYEVVREYYINDAGAQVDVLVESVYLRYKEVLGENIVIGSGLYPGLYLKDIGKLLY
QEYGSGLLGMDYSQRRRIIRDVSLMYLMKLIKEDLALLGIKHDIFTSESQLQKDNIVQKCVELLQEKQLIYYGTLDQPKG
TEGINWKPRTQMLFKSTDFGDDVDRALQKADGSWTYFANDIAYHFYKISRGFQHMILELGSDHIGYVKRLKAAVKALSDG
NATIDIKLHSIVNFLDNGAQVKMSKRSGEFLTIKDVIEKVGKDVVRFIMLTRKSDVVLDFDFAKVVEQSKNNPVFYVQYA
HARVHSLIRNAPKILEIELVDFSVLSSKEEILLIKLLAKWQDIVEISAKTAEPHRITFYLIEVAEAFHALWGYGNKSTDM
RFIVDNNINLTSARIYLAKSVGYVIASGLTIFSIVPLTEMK

Sequences:

>Translated_601_residues
MLLLFTFNIAKNLYNSKIIKELLNIMSVACTIRRHIIEKLHVLNIDNFVVTNESILAKLIVDYPNNPDHGDLYTNAALIL
SKYIKKNPMDIAKILVDEFSSIKEISDINVVKPGFINFNISLDVWYEIIISINRLKEKFGHVNFGNGKRVNIEFVSANPT
GPMHIGHARGAIFGDVLANLLERVGYEVVREYYINDAGAQVDVLVESVYLRYKEVLGENIVIGSGLYPGLYLKDIGKLLY
QEYGSGLLGMDYSQRRRIIRDVSLMYLMKLIKEDLALLGIKHDIFTSESQLQKDNIVQKCVELLQEKQLIYYGTLDQPKG
TEGINWKPRTQMLFKSTDFGDDVDRALQKADGSWTYFANDIAYHFYKISRGFQHMILELGSDHIGYVKRLKAAVKALSDG
NATIDIKLHSIVNFLDNGAQVKMSKRSGEFLTIKDVIEKVGKDVVRFIMLTRKSDVVLDFDFAKVVEQSKNNPVFYVQYA
HARVHSLIRNAPKILEIELVDFSVLSSKEEILLIKLLAKWQDIVEISAKTAEPHRITFYLIEVAEAFHALWGYGNKSTDM
RFIVDNNINLTSARIYLAKSVGYVIASGLTIFSIVPLTEMK
>Mature_601_residues
MLLLFTFNIAKNLYNSKIIKELLNIMSVACTIRRHIIEKLHVLNIDNFVVTNESILAKLIVDYPNNPDHGDLYTNAALIL
SKYIKKNPMDIAKILVDEFSSIKEISDINVVKPGFINFNISLDVWYEIIISINRLKEKFGHVNFGNGKRVNIEFVSANPT
GPMHIGHARGAIFGDVLANLLERVGYEVVREYYINDAGAQVDVLVESVYLRYKEVLGENIVIGSGLYPGLYLKDIGKLLY
QEYGSGLLGMDYSQRRRIIRDVSLMYLMKLIKEDLALLGIKHDIFTSESQLQKDNIVQKCVELLQEKQLIYYGTLDQPKG
TEGINWKPRTQMLFKSTDFGDDVDRALQKADGSWTYFANDIAYHFYKISRGFQHMILELGSDHIGYVKRLKAAVKALSDG
NATIDIKLHSIVNFLDNGAQVKMSKRSGEFLTIKDVIEKVGKDVVRFIMLTRKSDVVLDFDFAKVVEQSKNNPVFYVQYA
HARVHSLIRNAPKILEIELVDFSVLSSKEEILLIKLLAKWQDIVEISAKTAEPHRITFYLIEVAEAFHALWGYGNKSTDM
RFIVDNNINLTSARIYLAKSVGYVIASGLTIFSIVPLTEMK

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI197100773, Length=625, Percent_Identity=24, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI15149476, Length=170, Percent_Identity=28.2352941176471, Blast_Score=76, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71985068, Length=561, Percent_Identity=24.0641711229947, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71985061, Length=561, Percent_Identity=24.0641711229947, Blast_Score=87, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320548, Length=587, Percent_Identity=24.5315161839864, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI18859963, Length=589, Percent_Identity=24.1086587436333, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 68315; Mature: 68315

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLFTFNIAKNLYNSKIIKELLNIMSVACTIRRHIIEKLHVLNIDNFVVTNESILAKLI
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHH
VDYPNNPDHGDLYTNAALILSKYIKKNPMDIAKILVDEFSSIKEISDINVVKPGFINFNI
HCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEE
SLDVWYEIIISINRLKEKFGHVNFGNGKRVNIEFVSANPTGPMHIGHARGAIFGDVLANL
EHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEECCCCHHHHHHHHHHH
LERVGYEVVREYYINDAGAQVDVLVESVYLRYKEVLGENIVIGSGLYPGLYLKDIGKLLY
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHH
QEYGSGLLGMDYSQRRRIIRDVSLMYLMKLIKEDLALLGIKHDIFTSESQLQKDNIVQKC
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHH
VELLQEKQLIYYGTLDQPKGTEGINWKPRTQMLFKSTDFGDDVDRALQKADGSWTYFAND
HHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHEEECCCCCCHHHHHHHHCCCCEEEEHHH
IAYHFYKISRGFQHMILELGSDHIGYVKRLKAAVKALSDGNATIDIKLHSIVNFLDNGAQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCE
VKMSKRSGEFLTIKDVIEKVGKDVVRFIMLTRKSDVVLDFDFAKVVEQSKNNPVFYVQYA
EEEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCEEEEEEH
HARVHSLIRNAPKILEIELVDFSVLSSKEEILLIKLLAKWQDIVEISAKTAEPHRITFYL
HHHHHHHHHCCCCEEEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHH
IEVAEAFHALWGYGNKSTDMRFIVDNNINLTSARIYLAKSVGYVIASGLTIFSIVPLTEM
HHHHHHHHHHHCCCCCCCCEEEEEECCCCEEHHEEEEHHHHHHHHHCCCCEEEEECCCCC
K
C
>Mature Secondary Structure
MLLLFTFNIAKNLYNSKIIKELLNIMSVACTIRRHIIEKLHVLNIDNFVVTNESILAKLI
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHH
VDYPNNPDHGDLYTNAALILSKYIKKNPMDIAKILVDEFSSIKEISDINVVKPGFINFNI
HCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEE
SLDVWYEIIISINRLKEKFGHVNFGNGKRVNIEFVSANPTGPMHIGHARGAIFGDVLANL
EHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEECCCCHHHHHHHHHHH
LERVGYEVVREYYINDAGAQVDVLVESVYLRYKEVLGENIVIGSGLYPGLYLKDIGKLLY
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHH
QEYGSGLLGMDYSQRRRIIRDVSLMYLMKLIKEDLALLGIKHDIFTSESQLQKDNIVQKC
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHH
VELLQEKQLIYYGTLDQPKGTEGINWKPRTQMLFKSTDFGDDVDRALQKADGSWTYFAND
HHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHEEECCCCCCHHHHHHHHCCCCEEEEHHH
IAYHFYKISRGFQHMILELGSDHIGYVKRLKAAVKALSDGNATIDIKLHSIVNFLDNGAQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCE
VKMSKRSGEFLTIKDVIEKVGKDVVRFIMLTRKSDVVLDFDFAKVVEQSKNNPVFYVQYA
EEEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCEEEEEEH
HARVHSLIRNAPKILEIELVDFSVLSSKEEILLIKLLAKWQDIVEISAKTAEPHRITFYL
HHHHHHHHHCCCCEEEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHH
IEVAEAFHALWGYGNKSTDMRFIVDNNINLTSARIYLAKSVGYVIASGLTIFSIVPLTEM
HHHHHHHHHHHCCCCCCCCEEEEEECCCCEEHHEEEEHHHHHHHHHCCCCEEEEECCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA