Definition Ehrlichia ruminantium str. Gardel, complete genome.
Accession NC_006831
Length 1,499,920

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The map label for this gene is ileS

Identifier: 161986610

GI number: 161986610

Start: 806397

End: 809714

Strand: Reverse

Name: ileS

Synonym: ERGA_CDS_05000

Alternate gene names: 161986610

Gene position: 809714-806397 (Counterclockwise)

Preceding gene: 58617231

Following gene: 58617226

Centisome position: 53.98

GC content: 29.81

Gene sequence:

>3318_bases
ATGAAAGAATATAACTCACAATTCACAGAAGGATCAGATTTCTCATTAATAGAAGAGCAGATATTAGAATTTTGGAAAGA
AAATAATATTTTTAAAAAATCTATAGAAAATCGTGATGAGAAAAGGAGATTTGTATTCTATGACGGTCCTCCATTTGCCA
ATGGGTTACCTCACTATGGTCATTTACTTACTGGGTTTATTAAAGATACAGTTGCGCGCTATAAGACTATGGCAGGGTTT
AGGGTGGATAGAAGATTTGGCTGGGATTGTCATGGATTACCAGCTGAAATGCTTGCAGAGAAAGAATTGGGGGTATCTGG
AAAATTAGCGATAGAAGAATTTGGAATAGAGAAGTTTAATAACTATTGTCGTAATTCAGTAATGAAATTTTCAAGAGAGT
GGAAACAGTATATTGATAGACAGTCACGTTGGGTGGATTTTGAAAATGACTATAAGACAATGAATTTGTCTTTTATGGAA
TCGATAATGTGGTCATTTTATCAATTATGGCAAAAAGGACTTATATATGAATCTATAAAAATAGTCCCGTATAGTTGGGC
ATGTCAGACACCATTATCAAATTTTGAAACCAGAATAGATAATGCGTATAGACAAAAGACAAGTAAAACAGTGACTTTAG
CGTTTGAATTATTAGATGCACCAAAATCTTTAATAGTAGATAATATAACAGCATATAAAATACTAGTGTGGACAACTACT
CCTTGGACCTTGCCTTGTAATCTTGCTTTAGCTATTAGCCCAAATATTAAGTATTGTGGAGCAATCATAAATAAAGAAAT
GTATATTTTTTCTAGGGCATATTTGAAAAACTTTGAAGATCATTGCAAGAAAAATAATATAGAATATCTGATACATAGTG
ATGATATTTGTTATTTGAGTTTAGAATATTTGTCTTATAAACCTGTATTTAATTATTTTATTGATATAAAAAATGCATTT
AAAGTTTTAGTTGCAGATTTTGTTGTAGAAGATGAAGGCACTGGAATAGTACATATGGCACCAGGTTTTGGGGAAGATGA
TTTTATATTATGTAAAAAACAAGGTATACCAGATATTGATGATAAGGATACTTCAAAATTACTTGCAACAATCTGTCCAA
TAGACGATGGAGGAAAGTTTACTGAGAGAATTTCAGATTTTGTTAATATGCATGTATTTGATACTAATGATCAGATCATA
AGTATATTAAAAGCAAAAAATCTTTGTTTTAAAACAGATCAATATTTACATAATTATCCGCACTGTTGGCGTACTGATAC
TCCATTAATATACAGAGCAATGTCATCTTGGTATGTTGAAGTTACAAAAATTAAAAATAGAATGATAGATCTAAACAAAG
ATGTAAATTGGATTCCTAGTCATATTCGTAGTGGACAATTTGGTAAATGGCTTGAAAATGCTAAGGATTGGGCAATCTCA
CGTAATAGATTTTGGGGAACTCCGTTGCCAGTATGGAAATCTGATAATCCTAATTATCCTAGGATTGATGTATATGGATC
AATAAAAAAAGTATTTGATGATATAAAAGCACTAGAAGAGGATTTTGATATACCTATAGATGATTTACATCGTCCATATA
TTGATAATTTAGTACGTCCCAATCCTGATGATCCGACTGGGAAGTCAATGATGAGACGTGTTACTGATGTATTTGATTGT
TGGTTTGAATCTGGATCGATGCCATATGCTCAACTTCATTATCCATTTGAAAATAAAGAGCTTTTTGAGAATTATTTTCC
AGCGGATTTTATTACTGAATATGTAGCTCAAACTAGGGGATGGTTTTATACATTATTTGTGTTGTCTACAGCTTTATTTG
ATAAACCTCCATTTAAGAATTGTATATGTCATGGTGTGGTATTAGATACTCAAGGACAAAAGTTGTCGAAAAGACTTAAT
AATTATGCTGATCCAATGGAGATATTTAAGCAATATGGCTCTGATGCTATGCGTTTTCTAATGTTATCTCATACAGTGTC
ATATGGTGGAGACTTATTATTGGATAAAGATGGTGTTATGGTACGTGATGTAATACGTAATGTAATAAAGCCAATGTGGA
ATAGTTATAATTTCTTTACTATTTATGCTGATATTGACAAAGTAAGCGCAAGGGTTATCTCTGATCTAGATGAAGTAGAT
AACATTATGGATAAATATATAATGTGTGAGTGTATCAGTACTATACAGTCCATATTTAATGCTATGGAAGAGTTTGATCA
GAGTGTCGGTAATTATGGATATAATATAAAAGCTGCATGTAATAGTATTGTACAATTTTTTGAAGTATTGAATAATTGGT
ATATAAGAAGATGTAGAAGTCGCTTTTGGTCATCAGAAATTACTAAAGATAAGGTAAATGCTTATAATACTTTATACACT
GTAATGTACTATATGGTAAAAGTATCAGCACCATTTTTGCCTGCTATTACTGAAGCAATTTGGCAAAAATTGAATTTCCA
GGAAGAGGAATCAGTACATTTATCATTATTGCCTAATATAGAGCATATTACGTTAAAAGATGAAGATCAGAAAAATATAC
AATATATGAAACTTATCATAAATATATGTGGTTGTGTGCTTTCTATTAGAAATGTTCGTAATATTAGAGTGAGACAACCT
TTAAATAAGATTACTATATATAGTTATAATAATAATAATGATTTATTTAACTTACCTGTAAAATACCAAAATATTTTGTT
AGATGAAATAAATGTAAAAAGCATAGTATTTAAGTCTAATATTGAGGATATTGCTTCGTTTCAGTTGAAACTTAATTTTC
CAGAATTAGGAAAAAGAATACCAGAAAAAATGAAAAACTTGATATCGTTGTTAAAGAGTAATCAATGGAAAGTACTGGAA
AATGGCCAACTAATGCTTGGTATTAGAGAAGGTGAATACTATATATTAGAAGACAATGAATATACATTAAATCTAAAGGT
TCACAGTGAATTTGCATCTACTATAACTTTGGGTCCAAATTTACTAGGAGTATTAGTATTAGATAATACACTAACTGATG
AATTAATTATGGAAGGTATAGCAAGAGATATTGTTAGGATAATTCAACAATCTAGGAAAGATAATAAGTTTAATGTTTCT
GATAAAATTGATGTAGTTATATGTACTCAAGACAAAATGGTTAAAAATTCAGTACAAGCATGGTACGAATATATTGTACA
ACAAACTCTATCTCTATCACTTGTTATACATGAAAATTTGGATGCTAATAACGTAGCAGAATATTGTAAAACTACAATGA
AAGATAGAAACTTAACTCTTTTTATTAAAAAGTTATAA

Upstream 100 bases:

>100_bases
ATATTAATATGAGTCAATAATTTTTACATATTTATAAACTGTGATTGCAGCTTATACAAATATGTGTATAGTAAAAACTT
TACACTTAATAACACATGTT

Downstream 100 bases:

>100_bases
TTTTCTTGAAATAAAATGTAAAAATATCTAAAGTTTTACTTATATTTTCTTTTTTAAGGAATTATGTATTTAGTCTATTT
AGTAGCTGGTTTTGTGGTAC

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1105; Mature: 1105

Protein sequence:

>1105_residues
MKEYNSQFTEGSDFSLIEEQILEFWKENNIFKKSIENRDEKRRFVFYDGPPFANGLPHYGHLLTGFIKDTVARYKTMAGF
RVDRRFGWDCHGLPAEMLAEKELGVSGKLAIEEFGIEKFNNYCRNSVMKFSREWKQYIDRQSRWVDFENDYKTMNLSFME
SIMWSFYQLWQKGLIYESIKIVPYSWACQTPLSNFETRIDNAYRQKTSKTVTLAFELLDAPKSLIVDNITAYKILVWTTT
PWTLPCNLALAISPNIKYCGAIINKEMYIFSRAYLKNFEDHCKKNNIEYLIHSDDICYLSLEYLSYKPVFNYFIDIKNAF
KVLVADFVVEDEGTGIVHMAPGFGEDDFILCKKQGIPDIDDKDTSKLLATICPIDDGGKFTERISDFVNMHVFDTNDQII
SILKAKNLCFKTDQYLHNYPHCWRTDTPLIYRAMSSWYVEVTKIKNRMIDLNKDVNWIPSHIRSGQFGKWLENAKDWAIS
RNRFWGTPLPVWKSDNPNYPRIDVYGSIKKVFDDIKALEEDFDIPIDDLHRPYIDNLVRPNPDDPTGKSMMRRVTDVFDC
WFESGSMPYAQLHYPFENKELFENYFPADFITEYVAQTRGWFYTLFVLSTALFDKPPFKNCICHGVVLDTQGQKLSKRLN
NYADPMEIFKQYGSDAMRFLMLSHTVSYGGDLLLDKDGVMVRDVIRNVIKPMWNSYNFFTIYADIDKVSARVISDLDEVD
NIMDKYIMCECISTIQSIFNAMEEFDQSVGNYGYNIKAACNSIVQFFEVLNNWYIRRCRSRFWSSEITKDKVNAYNTLYT
VMYYMVKVSAPFLPAITEAIWQKLNFQEEESVHLSLLPNIEHITLKDEDQKNIQYMKLIINICGCVLSIRNVRNIRVRQP
LNKITIYSYNNNNDLFNLPVKYQNILLDEINVKSIVFKSNIEDIASFQLKLNFPELGKRIPEKMKNLISLLKSNQWKVLE
NGQLMLGIREGEYYILEDNEYTLNLKVHSEFASTITLGPNLLGVLVLDNTLTDELIMEGIARDIVRIIQQSRKDNKFNVS
DKIDVVICTQDKMVKNSVQAWYEYIVQQTLSLSLVIHENLDANNVAEYCKTTMKDRNLTLFIKKL

Sequences:

>Translated_1105_residues
MKEYNSQFTEGSDFSLIEEQILEFWKENNIFKKSIENRDEKRRFVFYDGPPFANGLPHYGHLLTGFIKDTVARYKTMAGF
RVDRRFGWDCHGLPAEMLAEKELGVSGKLAIEEFGIEKFNNYCRNSVMKFSREWKQYIDRQSRWVDFENDYKTMNLSFME
SIMWSFYQLWQKGLIYESIKIVPYSWACQTPLSNFETRIDNAYRQKTSKTVTLAFELLDAPKSLIVDNITAYKILVWTTT
PWTLPCNLALAISPNIKYCGAIINKEMYIFSRAYLKNFEDHCKKNNIEYLIHSDDICYLSLEYLSYKPVFNYFIDIKNAF
KVLVADFVVEDEGTGIVHMAPGFGEDDFILCKKQGIPDIDDKDTSKLLATICPIDDGGKFTERISDFVNMHVFDTNDQII
SILKAKNLCFKTDQYLHNYPHCWRTDTPLIYRAMSSWYVEVTKIKNRMIDLNKDVNWIPSHIRSGQFGKWLENAKDWAIS
RNRFWGTPLPVWKSDNPNYPRIDVYGSIKKVFDDIKALEEDFDIPIDDLHRPYIDNLVRPNPDDPTGKSMMRRVTDVFDC
WFESGSMPYAQLHYPFENKELFENYFPADFITEYVAQTRGWFYTLFVLSTALFDKPPFKNCICHGVVLDTQGQKLSKRLN
NYADPMEIFKQYGSDAMRFLMLSHTVSYGGDLLLDKDGVMVRDVIRNVIKPMWNSYNFFTIYADIDKVSARVISDLDEVD
NIMDKYIMCECISTIQSIFNAMEEFDQSVGNYGYNIKAACNSIVQFFEVLNNWYIRRCRSRFWSSEITKDKVNAYNTLYT
VMYYMVKVSAPFLPAITEAIWQKLNFQEEESVHLSLLPNIEHITLKDEDQKNIQYMKLIINICGCVLSIRNVRNIRVRQP
LNKITIYSYNNNNDLFNLPVKYQNILLDEINVKSIVFKSNIEDIASFQLKLNFPELGKRIPEKMKNLISLLKSNQWKVLE
NGQLMLGIREGEYYILEDNEYTLNLKVHSEFASTITLGPNLLGVLVLDNTLTDELIMEGIARDIVRIIQQSRKDNKFNVS
DKIDVVICTQDKMVKNSVQAWYEYIVQQTLSLSLVIHENLDANNVAEYCKTTMKDRNLTLFIKKL
>Mature_1105_residues
MKEYNSQFTEGSDFSLIEEQILEFWKENNIFKKSIENRDEKRRFVFYDGPPFANGLPHYGHLLTGFIKDTVARYKTMAGF
RVDRRFGWDCHGLPAEMLAEKELGVSGKLAIEEFGIEKFNNYCRNSVMKFSREWKQYIDRQSRWVDFENDYKTMNLSFME
SIMWSFYQLWQKGLIYESIKIVPYSWACQTPLSNFETRIDNAYRQKTSKTVTLAFELLDAPKSLIVDNITAYKILVWTTT
PWTLPCNLALAISPNIKYCGAIINKEMYIFSRAYLKNFEDHCKKNNIEYLIHSDDICYLSLEYLSYKPVFNYFIDIKNAF
KVLVADFVVEDEGTGIVHMAPGFGEDDFILCKKQGIPDIDDKDTSKLLATICPIDDGGKFTERISDFVNMHVFDTNDQII
SILKAKNLCFKTDQYLHNYPHCWRTDTPLIYRAMSSWYVEVTKIKNRMIDLNKDVNWIPSHIRSGQFGKWLENAKDWAIS
RNRFWGTPLPVWKSDNPNYPRIDVYGSIKKVFDDIKALEEDFDIPIDDLHRPYIDNLVRPNPDDPTGKSMMRRVTDVFDC
WFESGSMPYAQLHYPFENKELFENYFPADFITEYVAQTRGWFYTLFVLSTALFDKPPFKNCICHGVVLDTQGQKLSKRLN
NYADPMEIFKQYGSDAMRFLMLSHTVSYGGDLLLDKDGVMVRDVIRNVIKPMWNSYNFFTIYADIDKVSARVISDLDEVD
NIMDKYIMCECISTIQSIFNAMEEFDQSVGNYGYNIKAACNSIVQFFEVLNNWYIRRCRSRFWSSEITKDKVNAYNTLYT
VMYYMVKVSAPFLPAITEAIWQKLNFQEEESVHLSLLPNIEHITLKDEDQKNIQYMKLIINICGCVLSIRNVRNIRVRQP
LNKITIYSYNNNNDLFNLPVKYQNILLDEINVKSIVFKSNIEDIASFQLKLNFPELGKRIPEKMKNLISLLKSNQWKVLE
NGQLMLGIREGEYYILEDNEYTLNLKVHSEFASTITLGPNLLGVLVLDNTLTDELIMEGIARDIVRIIQQSRKDNKFNVS
DKIDVVICTQDKMVKNSVQAWYEYIVQQTLSLSLVIHENLDANNVAEYCKTTMKDRNLTLFIKKL

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1073, Percent_Identity=37.4650512581547, Blast_Score=702, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1073, Percent_Identity=37.4650512581547, Blast_Score=702, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=841, Percent_Identity=26.7538644470868, Blast_Score=250, Evalue=5e-66,
Organism=Escherichia coli, GI2367096, Length=848, Percent_Identity=26.061320754717, Blast_Score=296, Evalue=7e-81,
Organism=Escherichia coli, GI1790708, Length=932, Percent_Identity=20.3862660944206, Blast_Score=140, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17541896, Length=1107, Percent_Identity=35.3206865401987, Blast_Score=702, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=870, Percent_Identity=23.7931034482759, Blast_Score=231, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17510661, Length=826, Percent_Identity=21.3075060532688, Blast_Score=155, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI72001587, Length=882, Percent_Identity=21.8820861678005, Blast_Score=135, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1098, Percent_Identity=35.063752276867, Blast_Score=648, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=846, Percent_Identity=24.2316784869976, Blast_Score=214, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6321531, Length=910, Percent_Identity=21.978021978022, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI28574730, Length=1069, Percent_Identity=36.3891487371375, Blast_Score=709, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1069, Percent_Identity=36.3891487371375, Blast_Score=709, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1069, Percent_Identity=36.3891487371375, Blast_Score=709, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=799, Percent_Identity=26.5331664580726, Blast_Score=246, Evalue=6e-65,
Organism=Drosophila melanogaster, GI17864482, Length=869, Percent_Identity=22.6697353279632, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24653289, Length=869, Percent_Identity=22.6697353279632, Blast_Score=159, Evalue=1e-38,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_EHRRG (Q5FH91)

Other databases:

- EMBL:   CR925677
- RefSeq:   YP_196426.2
- ProteinModelPortal:   Q5FH91
- STRING:   Q5FH91
- GeneID:   3268633
- GenomeReviews:   CR925677_GR
- KEGG:   erg:ERGA_CDS_05000
- eggNOG:   COG0060
- HOGENOM:   HBG577712
- OMA:   DCHGLPA
- ProtClustDB:   PRK06039
- BioCyc:   ERUM302409:ERGA_CDS_05000-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 129234; Mature: 129234

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 650-650

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MKEYNSQFTEGSDFSLIEEQILEFWKENNIFKKSIENRDEKRRFVFYDGPPFANGLPHYG
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCHHH
HLLTGFIKDTVARYKTMAGFRVDRRFGWDCHGLPAEMLAEKELGVSGKLAIEEFGIEKFN
HHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHCHHHHH
NYCRNSVMKFSREWKQYIDRQSRWVDFENDYKTMNLSFMESIMWSFYQLWQKGLIYESIK
HHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHCCCEECCEE
IVPYSWACQTPLSNFETRIDNAYRQKTSKTVTLAFELLDAPKSLIVDNITAYKILVWTTT
EEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCHHHHHCCCEEEEEEEEECC
PWTLPCNLALAISPNIKYCGAIINKEMYIFSRAYLKNFEDHCKKNNIEYLIHSDDICYLS
CCEECCCEEEEECCCCHHHHHHHCCHHHHHHHHHHHCHHHHHCCCCCEEEEECCCEEEEE
LEYLSYKPVFNYFIDIKNAFKVLVADFVVEDEGTGIVHMAPGFGEDDFILCKKQGIPDID
EHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCEEEEECCCCCCCC
DKDTSKLLATICPIDDGGKFTERISDFVNMHVFDTNDQIISILKAKNLCFKTDQYLHNYP
CCHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEECCCHHHHHHHHHCCCCCCCHHHHHCCC
HCWRTDTPLIYRAMSSWYVEVTKIKNRMIDLNKDVNWIPSHIRSGQFGKWLENAKDWAIS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHCCCCCHHHHHHHHHHCCC
RNRFWGTPLPVWKSDNPNYPRIDVYGSIKKVFDDIKALEEDFDIPIDDLHRPYIDNLVRP
CCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHCCCC
NPDDPTGKSMMRRVTDVFDCWFESGSMPYAQLHYPFENKELFENYFPADFITEYVAQTRG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCCHHHHHHHHHHHCC
WFYTLFVLSTALFDKPPFKNCICHGVVLDTQGQKLSKRLNNYADPMEIFKQYGSDAMRFL
HHHHHHHHHHHHHCCCCHHHHHEECEEEECCCHHHHHHHHCCCCHHHHHHHHCHHHHHHH
MLSHTVSYGGDLLLDKDGVMVRDVIRNVIKPMWNSYNFFTIYADIDKVSARVISDLDEVD
HHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHH
NIMDKYIMCECISTIQSIFNAMEEFDQSVGNYGYNIKAACNSIVQFFEVLNNWYIRRCRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RFWSSEITKDKVNAYNTLYTVMYYMVKVSAPFLPAITEAIWQKLNFQEEESVHLSLLPNI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCC
EHITLKDEDQKNIQYMKLIINICGCVLSIRNVRNIRVRQPLNKITIYSYNNNNDLFNLPV
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCEEEEEEECCCCCEEECCH
KYQNILLDEINVKSIVFKSNIEDIASFQLKLNFPELGKRIPEKMKNLISLLKSNQWKVLE
HHHHHHHCCCCHHHEEECCCHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEE
NGQLMLGIREGEYYILEDNEYTLNLKVHSEFASTITLGPNLLGVLVLDNTLTDELIMEGI
CCEEEEEEECCCEEEEECCEEEEEEEEECCHHHHEEECCCEEEEEEECCCHHHHHHHHHH
ARDIVRIIQQSRKDNKFNVSDKIDVVICTQDKMVKNSVQAWYEYIVQQTLSLSLVIHENL
HHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEEEEECCC
DANNVAEYCKTTMKDRNLTLFIKKL
CHHHHHHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure
MKEYNSQFTEGSDFSLIEEQILEFWKENNIFKKSIENRDEKRRFVFYDGPPFANGLPHYG
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCHHH
HLLTGFIKDTVARYKTMAGFRVDRRFGWDCHGLPAEMLAEKELGVSGKLAIEEFGIEKFN
HHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHCHHHHH
NYCRNSVMKFSREWKQYIDRQSRWVDFENDYKTMNLSFMESIMWSFYQLWQKGLIYESIK
HHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHCCCEECCEE
IVPYSWACQTPLSNFETRIDNAYRQKTSKTVTLAFELLDAPKSLIVDNITAYKILVWTTT
EEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCHHHHHCCCEEEEEEEEECC
PWTLPCNLALAISPNIKYCGAIINKEMYIFSRAYLKNFEDHCKKNNIEYLIHSDDICYLS
CCEECCCEEEEECCCCHHHHHHHCCHHHHHHHHHHHCHHHHHCCCCCEEEEECCCEEEEE
LEYLSYKPVFNYFIDIKNAFKVLVADFVVEDEGTGIVHMAPGFGEDDFILCKKQGIPDID
EHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCEEEEECCCCCCCC
DKDTSKLLATICPIDDGGKFTERISDFVNMHVFDTNDQIISILKAKNLCFKTDQYLHNYP
CCHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEECCCHHHHHHHHHCCCCCCCHHHHHCCC
HCWRTDTPLIYRAMSSWYVEVTKIKNRMIDLNKDVNWIPSHIRSGQFGKWLENAKDWAIS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHCCCCCHHHHHHHHHHCCC
RNRFWGTPLPVWKSDNPNYPRIDVYGSIKKVFDDIKALEEDFDIPIDDLHRPYIDNLVRP
CCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHCCCC
NPDDPTGKSMMRRVTDVFDCWFESGSMPYAQLHYPFENKELFENYFPADFITEYVAQTRG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCCHHHHHHHHHHHCC
WFYTLFVLSTALFDKPPFKNCICHGVVLDTQGQKLSKRLNNYADPMEIFKQYGSDAMRFL
HHHHHHHHHHHHHCCCCHHHHHEECEEEECCCHHHHHHHHCCCCHHHHHHHHCHHHHHHH
MLSHTVSYGGDLLLDKDGVMVRDVIRNVIKPMWNSYNFFTIYADIDKVSARVISDLDEVD
HHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHH
NIMDKYIMCECISTIQSIFNAMEEFDQSVGNYGYNIKAACNSIVQFFEVLNNWYIRRCRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RFWSSEITKDKVNAYNTLYTVMYYMVKVSAPFLPAITEAIWQKLNFQEEESVHLSLLPNI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCC
EHITLKDEDQKNIQYMKLIINICGCVLSIRNVRNIRVRQPLNKITIYSYNNNNDLFNLPV
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCEEEEEEECCCCCEEECCH
KYQNILLDEINVKSIVFKSNIEDIASFQLKLNFPELGKRIPEKMKNLISLLKSNQWKVLE
HHHHHHHCCCCHHHEEECCCHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEE
NGQLMLGIREGEYYILEDNEYTLNLKVHSEFASTITLGPNLLGVLVLDNTLTDELIMEGI
CCEEEEEEECCCEEEEECCEEEEEEEEECCHHHHEEECCCEEEEEEECCCHHHHHHHHHH
ARDIVRIIQQSRKDNKFNVSDKIDVVICTQDKMVKNSVQAWYEYIVQQTLSLSLVIHENL
HHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEEEEECCC
DANNVAEYCKTTMKDRNLTLFIKKL
CHHHHHHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA