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The map label for this gene is nuoC [H]

Identifier: 58617034

GI number: 58617034

Start: 509688

End: 510263

Strand: Reverse

Name: nuoC [H]

Synonym: ERGA_CDS_03070

Alternate gene names: 58617034

Gene position: 510263-509688 (Counterclockwise)

Preceding gene: 58617036

Following gene: 58617027

Centisome position: 34.02

GC content: 27.95

Gene sequence:

>576_bases
ATGTCAGATATAGATAATACTCTTGAAGAGATTATGACACATATTAATACATGTTTAAACGTAAAATGCATTGCACAAGA
TAGTACAACATTAGAATTCTACTCAACACCACAAGATATTCATAATCATATTTTATTTCTATGTAATGACAGAATATGTA
AATTTCAAATTCTTATTGATATTTTTATAGTTGATTACCCACATAGAGAAGCTAGATTTGAGATAATCTATTCATTATTA
AGTATAGCTAATAATATAAGAATCTTTTGTAAGGTTTCATTACATGAAAATGAAAATATCACATCCATTACTAATATCTT
TAATGCTGCAGGTTGGTTTGAACGAGAAGCATTCGATATGTATGGGATATTATTTACTAACAATCCAGACTTAAGAAGAA
TTTTAACAGATTATGGATTTTCTGGTCACCCTATGCTTAAAGATTTTCCTTTAAGTGGATATAAAGAAGTACGATATGAC
ATAGCAAAAAAAGAAGTAATATATGAACCTGTAAACCTACAACAAGATTTTCGCTCATTTGATTTTCTATCTCCATGGAA
AGAACACAAACCCTAA

Upstream 100 bases:

>100_bases
TCAAATAATTAAATATAAACACTATGTAATATCTTAATTTAGAAAAATAAGGTATAGTAAACTTACATCTGTATAAATTT
AACTATCAAATAGGTATATA

Downstream 100 bases:

>100_bases
TATAAGTAGTTCTACATTTATATACTTTTGTCTATATTACAACACAATTGTAGTACAAATTTTATTTAACAGTGTTATGT
TGATGAAAATTAATTGAAAA

Product: NADH-quinone oxidoreductase chain C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MSDIDNTLEEIMTHINTCLNVKCIAQDSTTLEFYSTPQDIHNHILFLCNDRICKFQILIDIFIVDYPHREARFEIIYSLL
SIANNIRIFCKVSLHENENITSITNIFNAAGWFEREAFDMYGILFTNNPDLRRILTDYGFSGHPMLKDFPLSGYKEVRYD
IAKKEVIYEPVNLQQDFRSFDFLSPWKEHKP

Sequences:

>Translated_191_residues
MSDIDNTLEEIMTHINTCLNVKCIAQDSTTLEFYSTPQDIHNHILFLCNDRICKFQILIDIFIVDYPHREARFEIIYSLL
SIANNIRIFCKVSLHENENITSITNIFNAAGWFEREAFDMYGILFTNNPDLRRILTDYGFSGHPMLKDFPLSGYKEVRYD
IAKKEVIYEPVNLQQDFRSFDFLSPWKEHKP
>Mature_190_residues
SDIDNTLEEIMTHINTCLNVKCIAQDSTTLEFYSTPQDIHNHILFLCNDRICKFQILIDIFIVDYPHREARFEIIYSLLS
IANNIRIFCKVSLHENENITSITNIFNAAGWFEREAFDMYGILFTNNPDLRRILTDYGFSGHPMLKDFPLSGYKEVRYDI
AKKEVIYEPVNLQQDFRSFDFLSPWKEHKP

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=187, Percent_Identity=45.4545454545455, Blast_Score=165, Evalue=3e-41,
Organism=Escherichia coli, GI145693162, Length=103, Percent_Identity=37.8640776699029, Blast_Score=81, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI32563621, Length=157, Percent_Identity=49.0445859872611, Blast_Score=158, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71990788, Length=157, Percent_Identity=49.0445859872611, Blast_Score=158, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24656494, Length=186, Percent_Identity=44.6236559139785, Blast_Score=162, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 22528; Mature: 22397

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIDNTLEEIMTHINTCLNVKCIAQDSTTLEFYSTPQDIHNHILFLCNDRICKFQILID
CCHHHHHHHHHHHHHHHHHCEEEEECCCCEEEEECCHHHHHHCEEEEECCCEEEHEEEEE
IFIVDYPHREARFEIIYSLLSIANNIRIFCKVSLHENENITSITNIFNAAGWFEREAFDM
EEEECCCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHE
YGILFTNNPDLRRILTDYGFSGHPMLKDFPLSGYKEVRYDIAKKEVIYEPVNLQQDFRSF
EEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCHHHHHHC
DFLSPWKEHKP
CCCCCHHCCCC
>Mature Secondary Structure 
SDIDNTLEEIMTHINTCLNVKCIAQDSTTLEFYSTPQDIHNHILFLCNDRICKFQILID
CHHHHHHHHHHHHHHHHHCEEEEECCCCEEEEECCHHHHHHCEEEEECCCEEEHEEEEE
IFIVDYPHREARFEIIYSLLSIANNIRIFCKVSLHENENITSITNIFNAAGWFEREAFDM
EEEECCCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHE
YGILFTNNPDLRRILTDYGFSGHPMLKDFPLSGYKEVRYDIAKKEVIYEPVNLQQDFRSF
EEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCHHHHHHC
DFLSPWKEHKP
CCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA