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The map label for this gene is znuA [H]

Identifier: 58616985

GI number: 58616985

Start: 421946

End: 422809

Strand: Reverse

Name: znuA [H]

Synonym: ERGA_CDS_02580

Alternate gene names: 58616985

Gene position: 422809-421946 (Counterclockwise)

Preceding gene: 58616989

Following gene: 58616984

Centisome position: 28.19

GC content: 26.16

Gene sequence:

>864_bases
ATGAAACATATAATCTTTCTTTTATTTCTTTACATATCACTATACCCTATTACAGGATATTCTGTACCAAAAATTATAGC
AACTATAAACCCAATATATTCATTAGTTGACGCAGTAACAGAAGGTGTAACAAAGCCAGTCTTATTAATCAATCAGCAAA
TTTCTATACATGATTATATGTTAAAACCCTCAGATAAAAGAAAAATAAGAAGTAGTAATGTAATTTTTTATGTAGATGAT
CATCTAGAAACTTTTATAAACAAAATAAAAGATAAAACTCTAATTAAGTTATCTGATGTAGTAGCATTACTACCATCAAG
ATATGACTCTAATTTCTCATACAAAGTTCACACAACATCAAATGATTTACACATATGGTTAAGTCCAGACAATGCAAAAA
AAATAGTAGAACACATAAAGTTAGTACTATGTAAAATAGATCCAGAGAACGCAGAAGTATATGATAAAAATGCTCGTTTA
ACAATAATACGAATAACAGAACTAGCAGAGAAAATTAAGCAATTACTTAATACTGTTAAAACAAAACCTTATGTTGTTAC
CCACGATGCATATCAATATTTTGAAAAGTATTTTGGACTTAATTTTATAACATCACTTTCTTCAAGTCATAATACAAATA
TTAGTGTTAAAAAGTTAACACATATACAAAAAGTTATCACTAAAAACAATATATCATGTATTTTTTCTGAGTCTCAAAAT
GATAAAATTAGAAATTTATTTTCTCAACATAAAGTAACATTTCAAATACTGGACCCTATAGGGAATATTGCACAAAAAGA
ATCGTACTTTGACATTATGCAAAACATTGCTAATAATTTTTTCAGTTGTCTATCAACTACATAA

Upstream 100 bases:

>100_bases
TTTTCTTAGCATAAGCAAATGACAAATCTTTAACATTTATAATATAGTCATTGACGTATCTATCATGATGTGAAAAAATT
TTATTTTTACCGAGTAAATT

Downstream 100 bases:

>100_bases
ACTAGACTTTGAAAATTAAATAAATCATAATATTTTACCAATGATAATGTAGTCGTAATGCTGAATGTATCATCAGTATT
AATAATCAATACTGTATATT

Product: high-affinity zinc uptake system protein znuA

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKHIIFLLFLYISLYPITGYSVPKIIATINPIYSLVDAVTEGVTKPVLLINQQISIHDYMLKPSDKRKIRSSNVIFYVDD
HLETFINKIKDKTLIKLSDVVALLPSRYDSNFSYKVHTTSNDLHIWLSPDNAKKIVEHIKLVLCKIDPENAEVYDKNARL
TIIRITELAEKIKQLLNTVKTKPYVVTHDAYQYFEKYFGLNFITSLSSSHNTNISVKKLTHIQKVITKNNISCIFSESQN
DKIRNLFSQHKVTFQILDPIGNIAQKESYFDIMQNIANNFFSCLSTT

Sequences:

>Translated_287_residues
MKHIIFLLFLYISLYPITGYSVPKIIATINPIYSLVDAVTEGVTKPVLLINQQISIHDYMLKPSDKRKIRSSNVIFYVDD
HLETFINKIKDKTLIKLSDVVALLPSRYDSNFSYKVHTTSNDLHIWLSPDNAKKIVEHIKLVLCKIDPENAEVYDKNARL
TIIRITELAEKIKQLLNTVKTKPYVVTHDAYQYFEKYFGLNFITSLSSSHNTNISVKKLTHIQKVITKNNISCIFSESQN
DKIRNLFSQHKVTFQILDPIGNIAQKESYFDIMQNIANNFFSCLSTT
>Mature_287_residues
MKHIIFLLFLYISLYPITGYSVPKIIATINPIYSLVDAVTEGVTKPVLLINQQISIHDYMLKPSDKRKIRSSNVIFYVDD
HLETFINKIKDKTLIKLSDVVALLPSRYDSNFSYKVHTTSNDLHIWLSPDNAKKIVEHIKLVLCKIDPENAEVYDKNARL
TIIRITELAEKIKQLLNTVKTKPYVVTHDAYQYFEKYFGLNFITSLSSSHNTNISVKKLTHIQKVITKNNISCIFSESQN
DKIRNLFSQHKVTFQILDPIGNIAQKESYFDIMQNIANNFFSCLSTT

Specific function: Involved in the high-affinity zinc uptake transport system. Required for survival and normal growth under low Zn (2+) concentrations. Also required for virulence and intracellular growth in macrophages [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=280, Percent_Identity=27.1428571428571, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 33082; Mature: 33082

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIIFLLFLYISLYPITGYSVPKIIATINPIYSLVDAVTEGVTKPVLLINQQISIHDYM
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEEEHEE
LKPSDKRKIRSSNVIFYVDDHLETFINKIKDKTLIKLSDVVALLPSRYDSNFSYKVHTTS
ECCCHHHHHCCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEECC
NDLHIWLSPDNAKKIVEHIKLVLCKIDPENAEVYDKNARLTIIRITELAEKIKQLLNTVK
CCEEEEECCCHHHHHHHHHHEEEEEECCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHC
TKPYVVTHDAYQYFEKYFGLNFITSLSSSHNTNISVKKLTHIQKVITKNNISCIFSESQN
CCCEEEEHHHHHHHHHHHCHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCCEEEEECCCC
DKIRNLFSQHKVTFQILDPIGNIAQKESYFDIMQNIANNFFSCLSTT
HHHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKHIIFLLFLYISLYPITGYSVPKIIATINPIYSLVDAVTEGVTKPVLLINQQISIHDYM
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEEEHEE
LKPSDKRKIRSSNVIFYVDDHLETFINKIKDKTLIKLSDVVALLPSRYDSNFSYKVHTTS
ECCCHHHHHCCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEECC
NDLHIWLSPDNAKKIVEHIKLVLCKIDPENAEVYDKNARLTIIRITELAEKIKQLLNTVK
CCEEEEECCCHHHHHHHHHHEEEEEECCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHC
TKPYVVTHDAYQYFEKYFGLNFITSLSSSHNTNISVKKLTHIQKVITKNNISCIFSESQN
CCCEEEEHHHHHHHHHHHCHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCCEEEEECCCC
DKIRNLFSQHKVTFQILDPIGNIAQKESYFDIMQNIANNFFSCLSTT
HHHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA