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The map label for this gene is coaX

Identifier: 58616901

GI number: 58616901

Start: 285570

End: 286343

Strand: Reverse

Name: coaX

Synonym: ERGA_CDS_01740

Alternate gene names: 58616901

Gene position: 286343-285570 (Counterclockwise)

Preceding gene: 58616902

Following gene: 58616899

Centisome position: 19.09

GC content: 28.94

Gene sequence:

>774_bases
ATGTTAATAATAGATATAGGAAATACAAATATTAAATTTGGAATTTGCATTAATAATCAAATAATACAAACGCTAAGGAT
ATCTTCACAACCAAGAAGAACAGCTGATGAATATTTCTTCTTTCTCAATACAATGAGAAACCAGTTAAATACTAACAATT
TTACAATTACTCATATCATTATCTCAAGTGTTGTTCCAAGCATAACAAAACCAATGATAGAGCTAAGTACACATTATTTC
AATATAACTCCTACAATAATCAATAATCAGCACGCTGATATTTGTAATATCAAGATAGATTTAAACGACAAATTATTAGG
ATCAGATAGACTAGCAAGTATCATAGGAGCAGTTACTCTATATCCAAATAAAAATTTATTAGTAATAAGTATGGGTACTG
CAACAGTATTTAATTTAATAAGTAAAGAGAGATCCATCTACGGACAAGTCATAACTCCTGGAGCACATATTATGGCACAA
AGTATGAGACAACACACAGCATTGTTGCCAGAAATATCTCAAATTAAAGTAAATAAAGTAGTACATAATACATTGTTTTA
CGCTATAGAAGCAGGCGTATATTGGGGATATATTGCTATGGTCGAAGGGATTGTAAAACAAATATTACACGAGGAAAACA
AAGATTTACACATAGTAGCAACAGGTGGAAATTCAATTTTATTTATTGACCACAAAAATTTCATTAAGAACATTGATCCA
GATTTAACAATGAAAGGCATGATATATTTACATAACATGCTATTTAACAAATAA

Upstream 100 bases:

>100_bases
TAGCAAATAAAATTAGCCTCGAGCTAGCAGAACTATTATCTGCAGATGGTTTTCCAACAGTAAGCCATGCAATAGGACAC
AACAATTGATATAGAAAATA

Downstream 100 bases:

>100_bases
TACCTTAATTATTTACATTTTTTTCTATTAATAGTTTTAGTAATGTAAATATATATTCAACATTCATATTAAAATAAAGT
ATATTTATGTTTTTTCATAT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLIIDIGNTNIKFGICINNQIIQTLRISSQPRRTADEYFFFLNTMRNQLNTNNFTITHIIISSVVPSITKPMIELSTHYF
NITPTIINNQHADICNIKIDLNDKLLGSDRLASIIGAVTLYPNKNLLVISMGTATVFNLISKERSIYGQVITPGAHIMAQ
SMRQHTALLPEISQIKVNKVVHNTLFYAIEAGVYWGYIAMVEGIVKQILHEENKDLHIVATGGNSILFIDHKNFIKNIDP
DLTMKGMIYLHNMLFNK

Sequences:

>Translated_257_residues
MLIIDIGNTNIKFGICINNQIIQTLRISSQPRRTADEYFFFLNTMRNQLNTNNFTITHIIISSVVPSITKPMIELSTHYF
NITPTIINNQHADICNIKIDLNDKLLGSDRLASIIGAVTLYPNKNLLVISMGTATVFNLISKERSIYGQVITPGAHIMAQ
SMRQHTALLPEISQIKVNKVVHNTLFYAIEAGVYWGYIAMVEGIVKQILHEENKDLHIVATGGNSILFIDHKNFIKNIDP
DLTMKGMIYLHNMLFNK
>Mature_257_residues
MLIIDIGNTNIKFGICINNQIIQTLRISSQPRRTADEYFFFLNTMRNQLNTNNFTITHIIISSVVPSITKPMIELSTHYF
NITPTIINNQHADICNIKIDLNDKLLGSDRLASIIGAVTLYPNKNLLVISMGTATVFNLISKERSIYGQVITPGAHIMAQ
SMRQHTALLPEISQIKVNKVVHNTLFYAIEAGVYWGYIAMVEGIVKQILHEENKDLHIVATGGNSILFIDHKNFIKNIDP
DLTMKGMIYLHNMLFNK

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_EHRRG (Q5FFD0)

Other databases:

- EMBL:   CR925677
- RefSeq:   YP_196100.1
- ProteinModelPortal:   Q5FFD0
- STRING:   Q5FFD0
- GeneID:   3267944
- GenomeReviews:   CR925677_GR
- KEGG:   erg:ERGA_CDS_01740
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13318
- BioCyc:   ERUM302409:ERGA_CDS_01740-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 29040; Mature: 29040

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 133-133

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIDIGNTNIKFGICINNQIIQTLRISSQPRRTADEYFFFLNTMRNQLNTNNFTITHII
CEEEEECCCEEEEEEEECHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHH
ISSVVPSITKPMIELSTHYFNITPTIINNQHADICNIKIDLNDKLLGSDRLASIIGAVTL
HHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCEEEEEEECCCCCCCCHHHHHHHHEEEE
YPNKNLLVISMGTATVFNLISKERSIYGQVITPGAHIMAQSMRQHTALLPEISQIKVNKV
ECCCCEEEEEECHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHH
VHNTLFYAIEAGVYWGYIAMVEGIVKQILHEENKDLHIVATGGNSILFIDHKNFIKNIDP
HHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECHHHHCCCCC
DLTMKGMIYLHNMLFNK
CCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLIIDIGNTNIKFGICINNQIIQTLRISSQPRRTADEYFFFLNTMRNQLNTNNFTITHII
CEEEEECCCEEEEEEEECHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHH
ISSVVPSITKPMIELSTHYFNITPTIINNQHADICNIKIDLNDKLLGSDRLASIIGAVTL
HHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCEEEEEEECCCCCCCCHHHHHHHHEEEE
YPNKNLLVISMGTATVFNLISKERSIYGQVITPGAHIMAQSMRQHTALLPEISQIKVNKV
ECCCCEEEEEECHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHH
VHNTLFYAIEAGVYWGYIAMVEGIVKQILHEENKDLHIVATGGNSILFIDHKNFIKNIDP
HHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECHHHHCCCCC
DLTMKGMIYLHNMLFNK
CCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA