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The map label for this gene is trpS [H]

Identifier: 58616832

GI number: 58616832

Start: 173092

End: 174114

Strand: Reverse

Name: trpS [H]

Synonym: ERGA_CDS_01050

Alternate gene names: 58616832

Gene position: 174114-173092 (Counterclockwise)

Preceding gene: 58616833

Following gene: 58616827

Centisome position: 11.61

GC content: 31.57

Gene sequence:

>1023_bases
TTGTTTATAATGGGTAAAGTTATGTCCATACCTGTTGTTTTATCTGGTATACAACCCACTGGTAGTATACATTTAGGGAA
TTATCTAGGCTTCATACGTAATGGTGTGTCTTTACAAAATTCATATAAGTGTTTCTTTTTTCTTGCTGATTTACATACTC
TAACATCTGAAGCTTACAATCCAGATGAACTTAAGAAAAATTCGATAAACACGCTAGCAACATACCTAGCATGCGGAATA
GATCCAGAAAATTCAGTGCTATTTTCACAGTCTTTTATTCCAGCACATACAGAGTTACTATGGATATTCAGTTGCATTAC
TTCAACAGGTCAACTAAATAGAATGACTCAATTTAAAGAAAAAAGTCGCAATAAAGTTTCTACAGCTTCTTTAGGATTGT
ACAGCTATCCTGTATTAATGGCAGCTGATATATTACTTTACCAAGCAAATATAGTACCTGTAGGCATTGATCAAAAACAA
CACCTAGAATTAGCACGAGACATTGCTCAAGCTTTTAATACAAAATACAATACGCAATACTTTCAACTGCCAGAACCATT
AATTGTACAGGAATCAGCAAAAATTATGAGTTTAAGAGACGGTAAAAAGAAAATGAGTAAATCTGATGTATCAGATTATT
CACGAATTAATTTAGAAGATAGTAACGACTTAATTGCTCAAAAAATTAACAAAGCGACCACTGACTCTATTGTAGGTTTT
GACTTGACAAGTTTAAACAATAGGCCTGCAATAAAGAATCTTGTTAATATCTATGCTACACTTTCAAATATTAGTATAGA
ACAAACATGTACTAACATTGCAAGCTTCACTACTAAACAATTTAAAGAAGAACTAACAGAATTAGTTATTAATAACATTG
CACCAATACGACAAAGATTAAGAGAGTTATTAGAAGACATAGAATATTTACGAAGCATATTAATGACAGGAAATAACAAG
GCTGCATCTATTGCACATAAGCACATAATAGAAATTAAAAAGATTGCAGGATATTGGTCATAA

Upstream 100 bases:

>100_bases
TATCTGCACGTTTGACTAAGTAGCTATTTATTACACATATTTAATAAGTTGATTACATTATTTGTTGTATATTTTATAAA
TATACTGTAAACTTAGTTGC

Downstream 100 bases:

>100_bases
TTATACAAAATTCATTAATACTCAAAGCCATCCTTTGGTTATTATTGTATGTGTCATGGTGTTTAAAAACATAAAACAGT
TTTTATTACCAATATGTAAA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MFIMGKVMSIPVVLSGIQPTGSIHLGNYLGFIRNGVSLQNSYKCFFFLADLHTLTSEAYNPDELKKNSINTLATYLACGI
DPENSVLFSQSFIPAHTELLWIFSCITSTGQLNRMTQFKEKSRNKVSTASLGLYSYPVLMAADILLYQANIVPVGIDQKQ
HLELARDIAQAFNTKYNTQYFQLPEPLIVQESAKIMSLRDGKKKMSKSDVSDYSRINLEDSNDLIAQKINKATTDSIVGF
DLTSLNNRPAIKNLVNIYATLSNISIEQTCTNIASFTTKQFKEELTELVINNIAPIRQRLRELLEDIEYLRSILMTGNNK
AASIAHKHIIEIKKIAGYWS

Sequences:

>Translated_340_residues
MFIMGKVMSIPVVLSGIQPTGSIHLGNYLGFIRNGVSLQNSYKCFFFLADLHTLTSEAYNPDELKKNSINTLATYLACGI
DPENSVLFSQSFIPAHTELLWIFSCITSTGQLNRMTQFKEKSRNKVSTASLGLYSYPVLMAADILLYQANIVPVGIDQKQ
HLELARDIAQAFNTKYNTQYFQLPEPLIVQESAKIMSLRDGKKKMSKSDVSDYSRINLEDSNDLIAQKINKATTDSIVGF
DLTSLNNRPAIKNLVNIYATLSNISIEQTCTNIASFTTKQFKEELTELVINNIAPIRQRLRELLEDIEYLRSILMTGNNK
AASIAHKHIIEIKKIAGYWS
>Mature_340_residues
MFIMGKVMSIPVVLSGIQPTGSIHLGNYLGFIRNGVSLQNSYKCFFFLADLHTLTSEAYNPDELKKNSINTLATYLACGI
DPENSVLFSQSFIPAHTELLWIFSCITSTGQLNRMTQFKEKSRNKVSTASLGLYSYPVLMAADILLYQANIVPVGIDQKQ
HLELARDIAQAFNTKYNTQYFQLPEPLIVQESAKIMSLRDGKKKMSKSDVSDYSRINLEDSNDLIAQKINKATTDSIVGF
DLTSLNNRPAIKNLVNIYATLSNISIEQTCTNIASFTTKQFKEELTELVINNIAPIRQRLRELLEDIEYLRSILMTGNNK
AASIAHKHIIEIKKIAGYWS

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=329, Percent_Identity=40.4255319148936, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI41352700, Length=177, Percent_Identity=46.8926553672316, Blast_Score=172, Evalue=3e-43,
Organism=Escherichia coli, GI1789786, Length=335, Percent_Identity=39.7014925373134, Blast_Score=262, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71982800, Length=334, Percent_Identity=36.8263473053892, Blast_Score=214, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI71982793, Length=332, Percent_Identity=36.7469879518072, Blast_Score=214, Evalue=7e-56,
Organism=Saccharomyces cerevisiae, GI6320474, Length=344, Percent_Identity=40.1162790697674, Blast_Score=234, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24666151, Length=327, Percent_Identity=40.9785932721713, Blast_Score=239, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 38193; Mature: 38193

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIMGKVMSIPVVLSGIQPTGSIHLGNYLGFIRNGVSLQNSYKCFFFLADLHTLTSEAYN
CEECCHHHHHHHHEECCCCCCCEEHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHCCCC
PDELKKNSINTLATYLACGIDPENSVLFSQSFIPAHTELLWIFSCITSTGQLNRMTQFKE
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
KSRNKVSTASLGLYSYPVLMAADILLYQANIVPVGIDQKQHLELARDIAQAFNTKYNTQY
HHCCCHHHHHCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCEE
FQLPEPLIVQESAKIMSLRDGKKKMSKSDVSDYSRINLEDSNDLIAQKINKATTDSIVGF
EECCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHEECCCCCCHHHHHHHHHHHCCCEEEE
DLTSLNNRPAIKNLVNIYATLSNISIEQTCTNIASFTTKQFKEELTELVINNIAPIRQRL
EHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RELLEDIEYLRSILMTGNNKAASIAHKHIIEIKKIAGYWS
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFIMGKVMSIPVVLSGIQPTGSIHLGNYLGFIRNGVSLQNSYKCFFFLADLHTLTSEAYN
CEECCHHHHHHHHEECCCCCCCEEHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHCCCC
PDELKKNSINTLATYLACGIDPENSVLFSQSFIPAHTELLWIFSCITSTGQLNRMTQFKE
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
KSRNKVSTASLGLYSYPVLMAADILLYQANIVPVGIDQKQHLELARDIAQAFNTKYNTQY
HHCCCHHHHHCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCEE
FQLPEPLIVQESAKIMSLRDGKKKMSKSDVSDYSRINLEDSNDLIAQKINKATTDSIVGF
EECCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHEECCCCCCHHHHHHHHHHHCCCEEEE
DLTSLNNRPAIKNLVNIYATLSNISIEQTCTNIASFTTKQFKEELTELVINNIAPIRQRL
EHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RELLEDIEYLRSILMTGNNKAASIAHKHIIEIKKIAGYWS
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]