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The map label for this gene is lytH [H]

Identifier: 56964715

GI number: 56964715

Start: 3072723

End: 3073787

Strand: Direct

Name: lytH [H]

Synonym: ABC2951

Alternate gene names: 56964715

Gene position: 3072723-3073787 (Clockwise)

Preceding gene: 56964713

Following gene: 56964737

Centisome position: 71.39

GC content: 44.88

Gene sequence:

>1065_bases
TTGGCCGAAAACTATACAAAACCCCATAGAAAGGAGCTAGCACAATTGTCTTATTTGCGACGCCGTGTATGGCTATGTTT
GCTTGTTGTTCTTCTTAGTTTTTCTAGTTTTTGGCCAGACACAGCTGCAAGTGCGCAAAAGCAGACAGATCCAAACTTAT
ATTCAGAAAGGCTTGCTTTGTATAAAAAAATGGAAGTTCTTACGAGCGTCCCTTGGCCCTATTTAGCAGCTGTCGACTCC
TACGAACGGGGTTTACGGAAAGCGTTAAGGGACCGAGAACAAGCAAAAGGCCTTGTGTCTATTTACTATCCAAAAGAAGA
ATGGGTTGGCGCACTTAATCCAAACATAAACGACAATGATCCAACGACAATCAGCTTATTTGAAGGAATCGGCCTTGATG
GAAATGGCGATGGGAAAGCGAACATTGAGGATGATGAAGACGTCCTTTATACATTTGCTCGCTATTTAGAGTCTCACGGT
TACTCAGATGAGGATTTCCGTATTGCCCTCTGGCATTTTTACCAACGTGAACAAAGCGTTAACATTGTCAGTGGCCATGC
CAAAGTATACGAAACGTTTCAAACGCTCGACTTACATCAACATGCTTTTGTCATGCCCCTTCACCATCATTATAGCTACC
GTAGCACGTGGGGAGCCAAGCGAGGCTGGGGCGGTAGGCGCATTCATGAAGGGACCGACATTTTCGCCAATTACAATGTC
CCGATCCAATCTTCTTCATACGGCATCGTTGAAACGATTGGTTGGAATCCTTACGGCGGCTGGCGTATAGGCATACGCGA
CCTTGACAACATTTATCACTATTACGCCCACTTAAATGGCTATGAAAAAGGATTAGAGAAAGGGTCGATTGTAAAGGCAG
GACAAGTCATCGGTTACTGTGGCAGCTCAGGCTACGGCAAACCAGGAACACAAGGTAAATTCCCGCCTCATCTTCATTAC
GGAATGTACAGGGATAACGGTATCAGCGAATGGTCATTTGACCCATTTCCTTCGTTAAAACAATGGGAGCGCGCGGACAA
AAACGCGAAAAAAAACAATTCGTAA

Upstream 100 bases:

>100_bases
GTACCATGAATTCTACCTCGAACCAACAAGGGAAACGGAATTATTCCAACATTAGTACAAGCTGCAACTGGTAAAGATTC
TCTGTCATCATTTCGGCCAA

Downstream 100 bases:

>100_bases
ACAAATAAGCCTGCCAGTCGCTCGCATTAGTCGAGATCCTGGCAGGCTGTTAGGGTTATGATGATTGGGCTGCTTTCTTG
CCTGAAGCTTGTTTATTAAA

Product: metalloendopeptidase

Products: NA

Alternate protein names: Peptidoglycan hydrolase; Sporulation-specific endopeptidase [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MAENYTKPHRKELAQLSYLRRRVWLCLLVVLLSFSSFWPDTAASAQKQTDPNLYSERLALYKKMEVLTSVPWPYLAAVDS
YERGLRKALRDREQAKGLVSIYYPKEEWVGALNPNINDNDPTTISLFEGIGLDGNGDGKANIEDDEDVLYTFARYLESHG
YSDEDFRIALWHFYQREQSVNIVSGHAKVYETFQTLDLHQHAFVMPLHHHYSYRSTWGAKRGWGGRRIHEGTDIFANYNV
PIQSSSYGIVETIGWNPYGGWRIGIRDLDNIYHYYAHLNGYEKGLEKGSIVKAGQVIGYCGSSGYGKPGTQGKFPPHLHY
GMYRDNGISEWSFDPFPSLKQWERADKNAKKNNS

Sequences:

>Translated_354_residues
MAENYTKPHRKELAQLSYLRRRVWLCLLVVLLSFSSFWPDTAASAQKQTDPNLYSERLALYKKMEVLTSVPWPYLAAVDS
YERGLRKALRDREQAKGLVSIYYPKEEWVGALNPNINDNDPTTISLFEGIGLDGNGDGKANIEDDEDVLYTFARYLESHG
YSDEDFRIALWHFYQREQSVNIVSGHAKVYETFQTLDLHQHAFVMPLHHHYSYRSTWGAKRGWGGRRIHEGTDIFANYNV
PIQSSSYGIVETIGWNPYGGWRIGIRDLDNIYHYYAHLNGYEKGLEKGSIVKAGQVIGYCGSSGYGKPGTQGKFPPHLHY
GMYRDNGISEWSFDPFPSLKQWERADKNAKKNNS
>Mature_353_residues
AENYTKPHRKELAQLSYLRRRVWLCLLVVLLSFSSFWPDTAASAQKQTDPNLYSERLALYKKMEVLTSVPWPYLAAVDSY
ERGLRKALRDREQAKGLVSIYYPKEEWVGALNPNINDNDPTTISLFEGIGLDGNGDGKANIEDDEDVLYTFARYLESHGY
SDEDFRIALWHFYQREQSVNIVSGHAKVYETFQTLDLHQHAFVMPLHHHYSYRSTWGAKRGWGGRRIHEGTDIFANYNVP
IQSSSYGIVETIGWNPYGGWRIGIRDLDNIYHYYAHLNGYEKGLEKGSIVKAGQVIGYCGSSGYGKPGTQGKFPPHLHYG
MYRDNGISEWSFDPFPSLKQWERADKNAKKNNS

Specific function: L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, is required for the endospore cortex maturation [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047 [H]

Pfam domain/function: PF01551 Peptidase_M23 [H]

EC number: NA

Molecular weight: Translated: 40657; Mature: 40526

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENYTKPHRKELAQLSYLRRRVWLCLLVVLLSFSSFWPDTAASAQKQTDPNLYSERLAL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHH
YKKMEVLTSVPWPYLAAVDSYERGLRKALRDREQAKGLVSIYYPKEEWVGALNPNINDND
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHCCCCCCCCCCCC
PTTISLFEGIGLDGNGDGKANIEDDEDVLYTFARYLESHGYSDEDFRIALWHFYQREQSV
CCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCC
NIVSGHAKVYETFQTLDLHQHAFVMPLHHHYSYRSTWGAKRGWGGRRIHEGTDIFANYNV
EEEECHHHHHHHHHHHHHCCCEEEEEHHHCCCHHHCCCCCCCCCCCEECCCCEEEEECCC
PIQSSSYGIVETIGWNPYGGWRIGIRDLDNIYHYYAHLNGYEKGLEKGSIVKAGQVIGYC
CCCCCCCCEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEC
GSSGYGKPGTQGKFPPHLHYGMYRDNGISEWSFDPFPSLKQWERADKNAKKNNS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AENYTKPHRKELAQLSYLRRRVWLCLLVVLLSFSSFWPDTAASAQKQTDPNLYSERLAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHH
YKKMEVLTSVPWPYLAAVDSYERGLRKALRDREQAKGLVSIYYPKEEWVGALNPNINDND
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHCCCCCCCCCCCC
PTTISLFEGIGLDGNGDGKANIEDDEDVLYTFARYLESHGYSDEDFRIALWHFYQREQSV
CCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCC
NIVSGHAKVYETFQTLDLHQHAFVMPLHHHYSYRSTWGAKRGWGGRRIHEGTDIFANYNV
EEEECHHHHHHHHHHHHHCCCEEEEEHHHCCCHHHCCCCCCCCCCCEECCCCEEEEECCC
PIQSSSYGIVETIGWNPYGGWRIGIRDLDNIYHYYAHLNGYEKGLEKGSIVKAGQVIGYC
CCCCCCCCEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEC
GSSGYGKPGTQGKFPPHLHYGMYRDNGISEWSFDPFPSLKQWERADKNAKKNNS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 12813075 [H]