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The map label for this gene is cotA [H]

Identifier: 56964414

GI number: 56964414

Start: 2779428

End: 2780957

Strand: Direct

Name: cotA [H]

Synonym: ABC2649

Alternate gene names: 56964414

Gene position: 2779428-2780957 (Clockwise)

Preceding gene: 56964413

Following gene: 56964425

Centisome position: 64.58

GC content: 46.86

Gene sequence:

>1530_bases
ATGGAATTAGAAAAATTTGTCGACCCTATGCCTATTATGAAAACAGCAATCCCTAAAAAAACAAGCAAGGATGGAGACTA
TTACGAAATTGAGATGAAGGAGTTTTCACAAAAACTGCATCGGGATTTAAACCCGACTCGCTTATGGGGGTATGATGGCC
AATTCCCTGGCCCCACGATTGAAGTGATGCGGGGAAAACCAGCTCGGATCAAATGGATGAACAACCTCCCTGATACCCAC
TTCCTTCCGATTGACCGATCGATACACCACGTTGCCCATGAACCAGAAGTCCGCACCGTCGTCCATTTGCATGGGAGCGA
AACGACACCAGCAAGCGATGGCTACCCTGAAGCTTGGTTTACAAAGGATTTTGCAGAAGTGGGATCTTTTTTTGAACAAG
AAACTTATGAGTACCCAAACGACCAAAGGGCTGCCACCCTCTGGTACCATGACCATGCGATGGGAATTACACGCCTTAAT
GTATATGCAGGGTTGAGTGGTCTATACATTATTCGTGACCCACGAGAAGAACAGTTAAACTTGCCAAAGGGAGAATTTGA
CATTCCATTGCTGATTCAAGACCGGTCTTTTAACGACGACGGCTCTCTCTTCTACCCAGCCCAGCCAGCCAATCCCGCGC
CAAACTTGCCGAATCCGTCGGTCTTGCCGTTTTTTGTCGGCGATACGATTTTAGTAAACGGAAAAGTTTGGCCTTACTTG
CAAGTTGAACCACGGAAGTACCGATTTCGCATTTTAAACGGATCCAATTCACGTTCCTACCAGCTAGCCCTTGATTCAGA
AGCACCCTTTTATCAAATCGCTTCAGACGGCGGTTTGTTAAGAAGGACTGTTTCTTTGCAGGCATTCGATATCCGTCCAG
CCGAACGGATTGAAGCCATCATTGATTTCAGTAAATTCGAAGGCCAAACGATCACACTGAAAAACAATGCAAGCACTGAC
GCCACAGCGGATGTGATGCAGTTTCAGGTCGTTCTTCCCTTATCCGGAGAAGACACAAGCATCATTCCTCAAAACCTATC
TTATATCCCGTCGCTTCAGCAAAACGACGTCAAACGGATACGAAACTTAAAAATTTCTGGGACGACGGACGAGTACGGCA
GGCCTCTCCTTTTGCTCAATAACAAACTGTGGAGTGACCCTGTTGAGGAAAAACCGTGTTTAGGAACGACGGAAATATGG
TCATTCGTCAATGTCACCAACGTCCCCCATCCCATGCATATCCACCTAGTCCAATTTCAACTCTTGGACCACCGGGCGTT
TAACGTTGAGCTGTACAATGAAAATGGCCAAATCGAATTAGTGGGGCCGACTATTCCGCCTAAAATCAATGAGCGAGGCT
GGAAAGACACAATCACTGCCCCTGCAGGGCAAATCACTCGCGTCATTGCCCGATTTGCGCCGTTTTCCGGGTACTATGTA
TGGCACTGCCACATTCTCGAGCATGAAGACTATGATATGATGCGTCCTTTCGTTGTTATTGATCCGAAAACAGAGAAGGA
AAGGCGATGA

Upstream 100 bases:

>100_bases
TTAAGAAAAAACGCTTTACCTATTTAGTGAAAGCGCCCAAGCAAAACCGTCAAACGGAACATTCCATATACCACTACCTA
CATGACAGGAGCGGATTTTT

Downstream 100 bases:

>100_bases
GGGGGGAAGGAGGTTGCCCCTGGCACCTACCCGATTGCCAGGGGACCTGTGTTTTGTCTAATGTCTGCTATCCTATTTAA
TCGAAAAACCAAAAATTTCA

Product: spore coat protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MELEKFVDPMPIMKTAIPKKTSKDGDYYEIEMKEFSQKLHRDLNPTRLWGYDGQFPGPTIEVMRGKPARIKWMNNLPDTH
FLPIDRSIHHVAHEPEVRTVVHLHGSETTPASDGYPEAWFTKDFAEVGSFFEQETYEYPNDQRAATLWYHDHAMGITRLN
VYAGLSGLYIIRDPREEQLNLPKGEFDIPLLIQDRSFNDDGSLFYPAQPANPAPNLPNPSVLPFFVGDTILVNGKVWPYL
QVEPRKYRFRILNGSNSRSYQLALDSEAPFYQIASDGGLLRRTVSLQAFDIRPAERIEAIIDFSKFEGQTITLKNNASTD
ATADVMQFQVVLPLSGEDTSIIPQNLSYIPSLQQNDVKRIRNLKISGTTDEYGRPLLLLNNKLWSDPVEEKPCLGTTEIW
SFVNVTNVPHPMHIHLVQFQLLDHRAFNVELYNENGQIELVGPTIPPKINERGWKDTITAPAGQITRVIARFAPFSGYYV
WHCHILEHEDYDMMRPFVVIDPKTEKERR

Sequences:

>Translated_509_residues
MELEKFVDPMPIMKTAIPKKTSKDGDYYEIEMKEFSQKLHRDLNPTRLWGYDGQFPGPTIEVMRGKPARIKWMNNLPDTH
FLPIDRSIHHVAHEPEVRTVVHLHGSETTPASDGYPEAWFTKDFAEVGSFFEQETYEYPNDQRAATLWYHDHAMGITRLN
VYAGLSGLYIIRDPREEQLNLPKGEFDIPLLIQDRSFNDDGSLFYPAQPANPAPNLPNPSVLPFFVGDTILVNGKVWPYL
QVEPRKYRFRILNGSNSRSYQLALDSEAPFYQIASDGGLLRRTVSLQAFDIRPAERIEAIIDFSKFEGQTITLKNNASTD
ATADVMQFQVVLPLSGEDTSIIPQNLSYIPSLQQNDVKRIRNLKISGTTDEYGRPLLLLNNKLWSDPVEEKPCLGTTEIW
SFVNVTNVPHPMHIHLVQFQLLDHRAFNVELYNENGQIELVGPTIPPKINERGWKDTITAPAGQITRVIARFAPFSGYYV
WHCHILEHEDYDMMRPFVVIDPKTEKERR
>Mature_509_residues
MELEKFVDPMPIMKTAIPKKTSKDGDYYEIEMKEFSQKLHRDLNPTRLWGYDGQFPGPTIEVMRGKPARIKWMNNLPDTH
FLPIDRSIHHVAHEPEVRTVVHLHGSETTPASDGYPEAWFTKDFAEVGSFFEQETYEYPNDQRAATLWYHDHAMGITRLN
VYAGLSGLYIIRDPREEQLNLPKGEFDIPLLIQDRSFNDDGSLFYPAQPANPAPNLPNPSVLPFFVGDTILVNGKVWPYL
QVEPRKYRFRILNGSNSRSYQLALDSEAPFYQIASDGGLLRRTVSLQAFDIRPAERIEAIIDFSKFEGQTITLKNNASTD
ATADVMQFQVVLPLSGEDTSIIPQNLSYIPSLQQNDVKRIRNLKISGTTDEYGRPLLLLNNKLWSDPVEEKPCLGTTEIW
SFVNVTNVPHPMHIHLVQFQLLDHRAFNVELYNENGQIELVGPTIPPKINERGWKDTITAPAGQITRVIARFAPFSGYYV
WHCHILEHEDYDMMRPFVVIDPKTEKERR

Specific function: Involved in brown pigmentation during sporogenesis [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.antibioticus phenoxazinone synthase (phsA) [H]

Homologues:

Organism=Escherichia coli, GI1786314, Length=509, Percent_Identity=28.8801571709234, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI1789394, Length=441, Percent_Identity=28.1179138321995, Blast_Score=128, Evalue=8e-31,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR008972 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 58424; Mature: 58424

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELEKFVDPMPIMKTAIPKKTSKDGDYYEIEMKEFSQKLHRDLNPTRLWGYDGQFPGPTI
CCHHHHCCCCCHHHHHCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCEEECCCCCCCCCEE
EVMRGKPARIKWMNNLPDTHFLPIDRSIHHVAHEPEVRTVVHLHGSETTPASDGYPEAWF
EEECCCCCEEEEECCCCCCEEEECCCCHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHH
TKDFAEVGSFFEQETYEYPNDQRAATLWYHDHAMGITRLNVYAGLSGLYIIRDPREEQLN
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEEEECCCEEEEEECCCHHHCC
LPKGEFDIPLLIQDRSFNDDGSLFYPAQPANPAPNLPNPSVLPFFVGDTILVNGKVWPYL
CCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCEEEECCEECEEE
QVEPRKYRFRILNGSNSRSYQLALDSEAPFYQIASDGGLLRRTVSLQAFDIRPAERIEAI
EECCCEEEEEEEECCCCCEEEEEECCCCCEEEEECCCCEEEEEEEEEEEECCHHHHHHHH
IDFSKFEGQTITLKNNASTDATADVMQFQVVLPLSGEDTSIIPQNLSYIPSLQQNDVKRI
HHHHHCCCCEEEEECCCCCCCCEEEEEEEEEEEECCCCCEECCCCCCCCCCCCHHHHHHH
RNLKISGTTDEYGRPLLLLNNKLWSDPVEEKPCLGTTEIWSFVNVTNVPHPMHIHLVQFQ
HEEEEECCCHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEE
LLDHRAFNVELYNENGQIELVGPTIPPKINERGWKDTITAPAGQITRVIARFAPFSGYYV
EECCEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEE
WHCHILEHEDYDMMRPFVVIDPKTEKERR
EEEEEEECCCCHHHCCEEEECCCCCCCCC
>Mature Secondary Structure
MELEKFVDPMPIMKTAIPKKTSKDGDYYEIEMKEFSQKLHRDLNPTRLWGYDGQFPGPTI
CCHHHHCCCCCHHHHHCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCEEECCCCCCCCCEE
EVMRGKPARIKWMNNLPDTHFLPIDRSIHHVAHEPEVRTVVHLHGSETTPASDGYPEAWF
EEECCCCCEEEEECCCCCCEEEECCCCHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHH
TKDFAEVGSFFEQETYEYPNDQRAATLWYHDHAMGITRLNVYAGLSGLYIIRDPREEQLN
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEEEECCCEEEEEECCCHHHCC
LPKGEFDIPLLIQDRSFNDDGSLFYPAQPANPAPNLPNPSVLPFFVGDTILVNGKVWPYL
CCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCEEEECCEECEEE
QVEPRKYRFRILNGSNSRSYQLALDSEAPFYQIASDGGLLRRTVSLQAFDIRPAERIEAI
EECCCEEEEEEEECCCCCEEEEEECCCCCEEEEECCCCEEEEEEEEEEEECCHHHHHHHH
IDFSKFEGQTITLKNNASTDATADVMQFQVVLPLSGEDTSIIPQNLSYIPSLQQNDVKRI
HHHHHCCCCEEEEECCCCCCCCEEEEEEEEEEEECCCCCEECCCCCCCCCCCCHHHHHHH
RNLKISGTTDEYGRPLLLLNNKLWSDPVEEKPCLGTTEIWSFVNVTNVPHPMHIHLVQFQ
HEEEEECCCHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEE
LLDHRAFNVELYNENGQIELVGPTIPPKINERGWKDTITAPAGQITRVIARFAPFSGYYV
EECCEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEE
WHCHILEHEDYDMMRPFVVIDPKTEKERR
EEEEEEECCCCHHHCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969499; 9455482; 9384377; 2821284; 3135411 [H]