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The map label for this gene is ykpA [H]

Identifier: 56963876

GI number: 56963876

Start: 2230771

End: 2232357

Strand: Direct

Name: ykpA [H]

Synonym: ABC2111

Alternate gene names: 56963876

Gene position: 2230771-2232357 (Clockwise)

Preceding gene: 56963875

Following gene: 56963882

Centisome position: 51.83

GC content: 42.16

Gene sequence:

>1587_bases
ATGATTACTGTAGCGAACGTTGGTTTGCAATATGGCGGACGCAAACTATTTGAAGACGTTAATATTAAATTTACGCCAGG
CAACTGTTATGGTTTAATCGGCGCCAATGGAGCTGGCAAATCGACCTTTTTGAAAATCCTTTCAGGGGAAATCGAATCTC
AGACAGGGCATGTTTCGATGAAAGAAGGTTCGCGCCTAGCTGTTCTTAAGCAAAACCATTTCGAATATGAACATGAAGAA
GTGTTGCAAACCGTCATTATGGGACATGCACGCCTCTATGAAGTGATGAAAGAAAAAGACGCCATTTATATGAAAGCTGA
GTTTTCAGATGAAGATGGCATGAAAGCAGCTGAGCTAGAAGGCGAATTTGCAGAATTAAACGGTTGGGAAGCTGAGTCAG
ATGCAGCCGTCCTATTAAAAGGGCTCGGCATTGGCGAAGACCAACATCATAAAACGTTGTCTGAGCTTGCTGAATCAGAC
AAAGTCAAAGTGCTTCTGGCACAAGCGCTATTTGGCAAACCGGATGTGCTTTTACTGGACGAGCCGACAAACGGCCTCGA
TTTAAAAGCGATTCAATGGTTGGAAGATTTTCTTATTAATTTTGAGAATACGGTCATTGTCGTTTCCCATGACCGCCATT
TCTTAAATAATGTCTGCACGCATATTGCCGATTTGGACTATGGGAAAATTGAGCTGTACGTTGGAAACTATGATTTTTGG
TATGAATCGAGCCAATTGGCCTTAAAAATGGCACAAGACCAAAACAAAAAGAAAGAAGAAAAAATCAAAGAGCTTGAGAA
CTTTATCGCTCGCTTTAGCGCCAATGCCTCCAAATCCAAACAGGCGACTTCGCGTAAAAAGCAATTAGAAAAAATCACCC
TTGACGACATTAAACCTTCCTCGCGCAAATACCCATACATCCACTTTTCGCCAGCACGTGAAATTGGAAATGATTTGCTT
TTGGTTGAAGGGTTGTCAAAAACCGTTGATGGTGAAAAAGTGTTGAACAATGTGTCGTTCCGCATGAACAAAGACGATAA
AATCGCTCTTGTTGGTTCAAACGATGTCGCCAAAACGACGCTATTTAAAATCTTAATGGGTGAAATCGAGCCTGACGAGG
GCACATTTAAATGGGGAATTACGACAAGCCAATCGTATTTTCCGAAAGACAACTCTGCCTTTTTTGAAGGAAACGAGCTA
AATCTTGTCGATTGGTTGCGTCAATACTCTCCTGAAGATGACAGTGATACGTTCTTGCGTGGTTTTCTTGGCAGAATGCT
CTTCTCTGGCGAAGAGGTGCTTAAACAAGCAAACGTTTTATCAGGTGGCGAAAAAGTCCGTTGCATGCTGTCAAAAATGA
TGCTCTCTGGCGCGAATGTGCTGCTGTTGGATGAACCGACAAACCATCTGGACTTAGAGTCGATTACAGCGCTCAACAAC
GGGTTGATTAATTTTAAAGGGTCGCTCTTGTTCAGTTCCCATGACCAACAATTCATTCGCACGATTTCAAATCGCGTCAT
TGAGTTGACAGCGGATGGCATCATAGACGAAGACTCGTATGAAGATTACTTAAAACATGTAAAATAA

Upstream 100 bases:

>100_bases
GCAACGGTTTAAACGGTAAACTACGTAGTAGTAGTAGATGAAAGAGATAGGGATCCGACAGCGGCATCCTTTTATGCTCA
ATGTGTAGGAGGCTTTTTTT

Downstream 100 bases:

>100_bases
ACATCGAACCCCCCGTTGCCTTAGCACGGGGGGTTCCTATTGCGACAATAAGCGCCTACTAGCCTTGAAAATACTCTTTA
TAATAGCCGCCCACTTTTCC

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MITVANVGLQYGGRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKILSGEIESQTGHVSMKEGSRLAVLKQNHFEYEHEE
VLQTVIMGHARLYEVMKEKDAIYMKAEFSDEDGMKAAELEGEFAELNGWEAESDAAVLLKGLGIGEDQHHKTLSELAESD
KVKVLLAQALFGKPDVLLLDEPTNGLDLKAIQWLEDFLINFENTVIVVSHDRHFLNNVCTHIADLDYGKIELYVGNYDFW
YESSQLALKMAQDQNKKKEEKIKELENFIARFSANASKSKQATSRKKQLEKITLDDIKPSSRKYPYIHFSPAREIGNDLL
LVEGLSKTVDGEKVLNNVSFRMNKDDKIALVGSNDVAKTTLFKILMGEIEPDEGTFKWGITTSQSYFPKDNSAFFEGNEL
NLVDWLRQYSPEDDSDTFLRGFLGRMLFSGEEVLKQANVLSGGEKVRCMLSKMMLSGANVLLLDEPTNHLDLESITALNN
GLINFKGSLLFSSHDQQFIRTISNRVIELTADGIIDEDSYEDYLKHVK

Sequences:

>Translated_528_residues
MITVANVGLQYGGRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKILSGEIESQTGHVSMKEGSRLAVLKQNHFEYEHEE
VLQTVIMGHARLYEVMKEKDAIYMKAEFSDEDGMKAAELEGEFAELNGWEAESDAAVLLKGLGIGEDQHHKTLSELAESD
KVKVLLAQALFGKPDVLLLDEPTNGLDLKAIQWLEDFLINFENTVIVVSHDRHFLNNVCTHIADLDYGKIELYVGNYDFW
YESSQLALKMAQDQNKKKEEKIKELENFIARFSANASKSKQATSRKKQLEKITLDDIKPSSRKYPYIHFSPAREIGNDLL
LVEGLSKTVDGEKVLNNVSFRMNKDDKIALVGSNDVAKTTLFKILMGEIEPDEGTFKWGITTSQSYFPKDNSAFFEGNEL
NLVDWLRQYSPEDDSDTFLRGFLGRMLFSGEEVLKQANVLSGGEKVRCMLSKMMLSGANVLLLDEPTNHLDLESITALNN
GLINFKGSLLFSSHDQQFIRTISNRVIELTADGIIDEDSYEDYLKHVK
>Mature_528_residues
MITVANVGLQYGGRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKILSGEIESQTGHVSMKEGSRLAVLKQNHFEYEHEE
VLQTVIMGHARLYEVMKEKDAIYMKAEFSDEDGMKAAELEGEFAELNGWEAESDAAVLLKGLGIGEDQHHKTLSELAESD
KVKVLLAQALFGKPDVLLLDEPTNGLDLKAIQWLEDFLINFENTVIVVSHDRHFLNNVCTHIADLDYGKIELYVGNYDFW
YESSQLALKMAQDQNKKKEEKIKELENFIARFSANASKSKQATSRKKQLEKITLDDIKPSSRKYPYIHFSPAREIGNDLL
LVEGLSKTVDGEKVLNNVSFRMNKDDKIALVGSNDVAKTTLFKILMGEIEPDEGTFKWGITTSQSYFPKDNSAFFEGNEL
NLVDWLRQYSPEDDSDTFLRGFLGRMLFSGEEVLKQANVLSGGEKVRCMLSKMMLSGANVLLLDEPTNHLDLESITALNN
GLINFKGSLLFSSHDQQFIRTISNRVIELTADGIIDEDSYEDYLKHVK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=539, Percent_Identity=30.6122448979592, Blast_Score=254, Evalue=2e-67,
Organism=Homo sapiens, GI27881506, Length=515, Percent_Identity=31.2621359223301, Blast_Score=233, Evalue=4e-61,
Organism=Homo sapiens, GI10947137, Length=515, Percent_Identity=31.2621359223301, Blast_Score=233, Evalue=4e-61,
Organism=Homo sapiens, GI69354671, Length=538, Percent_Identity=28.0669144981413, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI10947135, Length=538, Percent_Identity=28.0669144981413, Blast_Score=173, Evalue=5e-43,
Organism=Escherichia coli, GI1787041, Length=526, Percent_Identity=47.148288973384, Blast_Score=519, Evalue=1e-148,
Organism=Escherichia coli, GI1789751, Length=543, Percent_Identity=32.4125230202578, Blast_Score=274, Evalue=8e-75,
Organism=Escherichia coli, GI2367384, Length=533, Percent_Identity=30.0187617260788, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI1787182, Length=511, Percent_Identity=29.5499021526419, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1789864, Length=238, Percent_Identity=24.3697478991597, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788165, Length=196, Percent_Identity=26.0204081632653, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1786398, Length=261, Percent_Identity=25.2873563218391, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786872, Length=247, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790525, Length=492, Percent_Identity=22.5609756097561, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17555318, Length=533, Percent_Identity=28.7054409005629, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17553372, Length=551, Percent_Identity=30.6715063520871, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17559834, Length=549, Percent_Identity=27.3224043715847, Blast_Score=203, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6320874, Length=533, Percent_Identity=32.6454033771107, Blast_Score=236, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6321121, Length=520, Percent_Identity=30.7692307692308, Blast_Score=226, Evalue=6e-60,
Organism=Saccharomyces cerevisiae, GI6325030, Length=377, Percent_Identity=26.790450928382, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323278, Length=368, Percent_Identity=25.8152173913043, Blast_Score=93, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6324314, Length=369, Percent_Identity=26.8292682926829, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320266, Length=212, Percent_Identity=24.0566037735849, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24666836, Length=540, Percent_Identity=30.9259259259259, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24642252, Length=539, Percent_Identity=28.0148423005566, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI18859989, Length=539, Percent_Identity=28.0148423005566, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24641342, Length=545, Percent_Identity=29.7247706422018, Blast_Score=211, Evalue=9e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59361; Mature: 59361

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVANVGLQYGGRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKILSGEIESQTGHVSM
CEEEEECCHHHCCHHHHHCCCEEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCEEEE
KEGSRLAVLKQNHFEYEHEEVLQTVIMGHARLYEVMKEKDAIYMKAEFSDEDGMKAAELE
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEHHCC
GEFAELNGWEAESDAAVLLKGLGIGEDQHHKTLSELAESDKVKVLLAQALFGKPDVLLLD
CCHHHCCCCCCCCCCEEHEECCCCCCHHHHHHHHHHHCCCCCEEEEEHHHCCCCCEEEEE
EPTNGLDLKAIQWLEDFLINFENTVIVVSHDRHFLNNVCTHIADLDYGKIELYVGNYDFW
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YESSQLALKMAQDQNKKKEEKIKELENFIARFSANASKSKQATSRKKQLEKITLDDIKPS
ECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
SRKYPYIHFSPAREIGNDLLLVEGLSKTVDGEKVLNNVSFRMNKDDKIALVGSNDVAKTT
CCCCCEEEECCHHHCCCCEEEEECCCCCCCHHHHHHCCCEEECCCCEEEEECCCCHHHHH
LFKILMGEIEPDEGTFKWGITTSQSYFPKDNSAFFEGNELNLVDWLRQYSPEDDSDTFLR
HHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCEECCCCCCHHHHHHHCCCCCCCHHHHH
GFLGRMLFSGEEVLKQANVLSGGEKVRCMLSKMMLSGANVLLLDEPTNHLDLESITALNN
HHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCC
GLINFKGSLLFSSHDQQFIRTISNRVIELTADGIIDEDSYEDYLKHVK
CEEEEECEEEECCCHHHHHHHHHHCEEEEEECCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MITVANVGLQYGGRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKILSGEIESQTGHVSM
CEEEEECCHHHCCHHHHHCCCEEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCEEEE
KEGSRLAVLKQNHFEYEHEEVLQTVIMGHARLYEVMKEKDAIYMKAEFSDEDGMKAAELE
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEHHCC
GEFAELNGWEAESDAAVLLKGLGIGEDQHHKTLSELAESDKVKVLLAQALFGKPDVLLLD
CCHHHCCCCCCCCCCEEHEECCCCCCHHHHHHHHHHHCCCCCEEEEEHHHCCCCCEEEEE
EPTNGLDLKAIQWLEDFLINFENTVIVVSHDRHFLNNVCTHIADLDYGKIELYVGNYDFW
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YESSQLALKMAQDQNKKKEEKIKELENFIARFSANASKSKQATSRKKQLEKITLDDIKPS
ECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
SRKYPYIHFSPAREIGNDLLLVEGLSKTVDGEKVLNNVSFRMNKDDKIALVGSNDVAKTT
CCCCCEEEECCHHHCCCCEEEEECCCCCCCHHHHHHCCCEEECCCCEEEEECCCCHHHHH
LFKILMGEIEPDEGTFKWGITTSQSYFPKDNSAFFEGNELNLVDWLRQYSPEDDSDTFLR
HHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCEECCCCCCHHHHHHHCCCCCCCHHHHH
GFLGRMLFSGEEVLKQANVLSGGEKVRCMLSKMMLSGANVLLLDEPTNHLDLESITALNN
HHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCC
GLINFKGSLLFSSHDQQFIRTISNRVIELTADGIIDEDSYEDYLKHVK
CEEEEECEEEECCCHHHHHHHHHHCEEEEEECCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]