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The map label for this gene is ywfM [H]

Identifier: 56963724

GI number: 56963724

Start: 2073305

End: 2074336

Strand: Direct

Name: ywfM [H]

Synonym: ABC1959

Alternate gene names: 56963724

Gene position: 2073305-2074336 (Clockwise)

Preceding gene: 56963723

Following gene: 56963728

Centisome position: 48.17

GC content: 49.52

Gene sequence:

>1032_bases
ATGAACCAAAGCAGCTTCAACAAACGATTGCCGACGAACAAGATGTGCTCGTTTTCGGCCTTATTTGGCATTAGGCAAGG
ACGGCTCAAAAAGAGCGTATGGCCTTATGATGATTTAAGACAAATAGAACGATTGGAGCGATGGACGATGCCGATGGCGA
TTGTGTTCGTGCTATGTGCTGCGATGCTATGGGGAACAACAGGGACAGCGCAAGCATTTTTAATTGGCGCCCATCCGTTA
GTAGTGGGGGCTGCGCGGCTATTGCTCGGGGGAATGAGTTTACTCCTGTTTGCTATTTTGACTGGCAAATCGCTAAATAT
AAAGGGGTGGCCGAAATGGCCATTTTTTGTGAGTATTGCGGCTATGGCTGCTTACCAACCATTCTTTTTTACGGCTGTGT
CAATGACTGGCGTTGCGGCAGGAACCGTTATCGCCATTGGCAGTGCCCCAATAGTAGCAGGCTTGTTGGAGTGGGCCTTT
TTTAAGCGGGTTCCAGGAAAGCGGTGGATGCAAGCAACAGCCTTGGCGATTGCCGGCTGTGTGTTGCTAATGACCGCTGG
CGATCAGTCCGTAGTTGTGTCACCGCTAGGGCTTTTGTTTGCTATAGGGGCAGGGCTTTCCTTTGCTGCTTATACATTAG
CAAGCAAAGGGCTTCTAGCCAAAGGGGAGCCTGAAGTCGTCGTCGCATTTATCTTTTCTTTCAGCGCGATCGTGTTGTTG
CCAACGTTCTTTTTATTTGAGGTCAGCTGGCTGCTTCATTGGCAAAATGGGCTCGTTGTTTTGCATTTAGGCTTGCTTGC
GACTGGCTTGGCCTACATGCTTTTTGCGAAAGGACTAAAAGAAATTCCAGGTTCTCTTGCTGTAACGCTTGCATTAGCCG
AACCGCTTACTGCGGCCCTTCTAGGAGTCAGCCTTGTGGGGGAGTCGCTCTCTTTCTACTCATGGGGCGGCATTGCGTTG
CTGTTGCTTGGCCTTTTGCTTGCTTCTATTGCGCCAAAACAAACACAGTCAAAACGGAGTTTATCGCAGTAG

Upstream 100 bases:

>100_bases
GACGGGAAAGTGGCGCTAGAAGCAGAGCAGCTGGATTTGCAAATGGAAGATAACCCCCTTGTTTTGATCCATTCAGGCAA
CAGTGGCGCATCGAATTGGT

Downstream 100 bases:

>100_bases
GCGAAAAAAATAAGCAGGAGGGGGACCTGCTTATGAACGGTGTTCCTTTATGTTGTTCCCACTTTCAACACATGCCATTT
GCCACTTTCGGTTAAACGAG

Product: DMT family permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MNQSSFNKRLPTNKMCSFSALFGIRQGRLKKSVWPYDDLRQIERLERWTMPMAIVFVLCAAMLWGTTGTAQAFLIGAHPL
VVGAARLLLGGMSLLLFAILTGKSLNIKGWPKWPFFVSIAAMAAYQPFFFTAVSMTGVAAGTVIAIGSAPIVAGLLEWAF
FKRVPGKRWMQATALAIAGCVLLMTAGDQSVVVSPLGLLFAIGAGLSFAAYTLASKGLLAKGEPEVVVAFIFSFSAIVLL
PTFFLFEVSWLLHWQNGLVVLHLGLLATGLAYMLFAKGLKEIPGSLAVTLALAEPLTAALLGVSLVGESLSFYSWGGIAL
LLLGLLLASIAPKQTQSKRSLSQ

Sequences:

>Translated_343_residues
MNQSSFNKRLPTNKMCSFSALFGIRQGRLKKSVWPYDDLRQIERLERWTMPMAIVFVLCAAMLWGTTGTAQAFLIGAHPL
VVGAARLLLGGMSLLLFAILTGKSLNIKGWPKWPFFVSIAAMAAYQPFFFTAVSMTGVAAGTVIAIGSAPIVAGLLEWAF
FKRVPGKRWMQATALAIAGCVLLMTAGDQSVVVSPLGLLFAIGAGLSFAAYTLASKGLLAKGEPEVVVAFIFSFSAIVLL
PTFFLFEVSWLLHWQNGLVVLHLGLLATGLAYMLFAKGLKEIPGSLAVTLALAEPLTAALLGVSLVGESLSFYSWGGIAL
LLLGLLLASIAPKQTQSKRSLSQ
>Mature_343_residues
MNQSSFNKRLPTNKMCSFSALFGIRQGRLKKSVWPYDDLRQIERLERWTMPMAIVFVLCAAMLWGTTGTAQAFLIGAHPL
VVGAARLLLGGMSLLLFAILTGKSLNIKGWPKWPFFVSIAAMAAYQPFFFTAVSMTGVAAGTVIAIGSAPIVAGLLEWAF
FKRVPGKRWMQATALAIAGCVLLMTAGDQSVVVSPLGLLFAIGAGLSFAAYTLASKGLLAKGEPEVVVAFIFSFSAIVLL
PTFFLFEVSWLLHWQNGLVVLHLGLLATGLAYMLFAKGLKEIPGSLAVTLALAEPLTAALLGVSLVGESLSFYSWGGIAL
LLLGLLLASIAPKQTQSKRSLSQ

Specific function: Unknown

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Escherichia coli, GI1790092, Length=291, Percent_Identity=26.1168384879725, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004779
- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 36646; Mature: 36646

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSSFNKRLPTNKMCSFSALFGIRQGRLKKSVWPYDDLRQIERLERWTMPMAIVFVLCA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHH
AMLWGTTGTAQAFLIGAHPLVVGAARLLLGGMSLLLFAILTGKSLNIKGWPKWPFFVSIA
HHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
AMAAYQPFFFTAVSMTGVAAGTVIAIGSAPIVAGLLEWAFFKRVPGKRWMQATALAIAGC
HHHHHCHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VLLMTAGDQSVVVSPLGLLFAIGAGLSFAAYTLASKGLLAKGEPEVVVAFIFSFSAIVLL
HHEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
PTFFLFEVSWLLHWQNGLVVLHLGLLATGLAYMLFAKGLKEIPGSLAVTLALAEPLTAAL
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHH
LGVSLVGESLSFYSWGGIALLLLGLLLASIAPKQTQSKRSLSQ
HHHHHHHCCCCHHCCHHHHHHHHHHHHHHCCCCHHHHHHCCCC
>Mature Secondary Structure
MNQSSFNKRLPTNKMCSFSALFGIRQGRLKKSVWPYDDLRQIERLERWTMPMAIVFVLCA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHH
AMLWGTTGTAQAFLIGAHPLVVGAARLLLGGMSLLLFAILTGKSLNIKGWPKWPFFVSIA
HHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
AMAAYQPFFFTAVSMTGVAAGTVIAIGSAPIVAGLLEWAFFKRVPGKRWMQATALAIAGC
HHHHHCHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VLLMTAGDQSVVVSPLGLLFAIGAGLSFAAYTLASKGLLAKGEPEVVVAFIFSFSAIVLL
HHEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
PTFFLFEVSWLLHWQNGLVVLHLGLLATGLAYMLFAKGLKEIPGSLAVTLALAEPLTAAL
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHH
LGVSLVGESLSFYSWGGIALLLLGLLLASIAPKQTQSKRSLSQ
HHHHHHHCCCCHHCCHHHHHHHHHHHHHHCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]