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The map label for this gene is rrmA [C]

Identifier: 56963687

GI number: 56963687

Start: 2035690

End: 2036442

Strand: Direct

Name: rrmA [C]

Synonym: ABC1922

Alternate gene names: 56963687

Gene position: 2035690-2036442 (Clockwise)

Preceding gene: 56963685

Following gene: 56963689

Centisome position: 47.3

GC content: 45.15

Gene sequence:

>753_bases
ATGGCATATAGCAAGACCTTTTTAGAACAAGTAGAAACAGCAATGAAGCAGTCATTTAGCGGTTGGAATTTTGAGCAGTT
AAGAGGGCGAGTGAAAGAGGATGAGCTCGACTGGTCTTATCGGGAATGGGTCAAGGAGTCACTTAAGCAACGGACAGTGC
TGGATATGGGCACAGGCGGCGGCGAATTTTTGTCTTCGTGTGCTCCATTTCGAGGAAAGGTCTATGCGACAGAGGGGTAT
GAGCCCAATGTAGAAATTGCGCAAAAAGCATTAGCTCCGTTTGGCGTCAGTGTACGTTATATAGAAGATGATGACAATCT
GCCCTTTTCTGATGAGGCTTTTGACAGCATTATCAACCGTCATGAATCATACAGCGAGCAAGAATTAGCCCGTATATTAA
AACCAGGTGGAACGTTTATTACCCAACAGGCTGGCGGTGATGATTGCAAAGAAATCAACGAGGCGCTTTCACTTCCTTTA
AATACTGAATTTGCCGAATGGAAGCTGGAAGTGGCCGTTGACCGCTTAGTTGCACACGGCTTCAGCGTTGAAGCTAAGAG
GAAGGCTTTTCCAAAGCAGCGTTTTTTTGATATTGGTGCGCTTATTTATTACTTGCGGGCGATTCCCTGGCAAGCACCAG
GCTTTTCTGTGGAACGCCATCTGCCCCAGTTGGATCATATCAGCCAGGAAATAAAAAAGAACGGGTATTTTGAAACGACA
CAGCATCGATTCATCTTGAAAGCAAGAAAATAA

Upstream 100 bases:

>100_bases
TGCTCAAACTAGGGTTTACGTAACAACGGTGCAGAGGACCTCCACATAAATCGGGACAAATCGGCATATATCTGTTTATT
TATGGGGAGGAGTCAAAAAG

Downstream 100 bases:

>100_bases
AAAGGGCGGCTTTATGCCGTCCTTTCAGACTGTAGACAAACGCTCGCATACTTCGTCGTTGCCTCGGTCATATGCTCATG
AACCCCCGTTCTATTCACAT

Product: S-adenosylmethionine (SAM)-dependent methyltransferase

Products: S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

Alternate protein names: Methyltransferase; SAM-Dependent Methyltransferase; Methyltransferase Family Protein; Methyltransferase Domain Family; S-Adenosylmethionine-Dependent Methyltransferase; Methyltransferase Domain-Containing Protein; Ubiquinone/Menaquinone Biosynthesis Methylase; Methyltransferase Domain-Containing; SAM Methytransferase

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MAYSKTFLEQVETAMKQSFSGWNFEQLRGRVKEDELDWSYREWVKESLKQRTVLDMGTGGGEFLSSCAPFRGKVYATEGY
EPNVEIAQKALAPFGVSVRYIEDDDNLPFSDEAFDSIINRHESYSEQELARILKPGGTFITQQAGGDDCKEINEALSLPL
NTEFAEWKLEVAVDRLVAHGFSVEAKRKAFPKQRFFDIGALIYYLRAIPWQAPGFSVERHLPQLDHISQEIKKNGYFETT
QHRFILKARK

Sequences:

>Translated_250_residues
MAYSKTFLEQVETAMKQSFSGWNFEQLRGRVKEDELDWSYREWVKESLKQRTVLDMGTGGGEFLSSCAPFRGKVYATEGY
EPNVEIAQKALAPFGVSVRYIEDDDNLPFSDEAFDSIINRHESYSEQELARILKPGGTFITQQAGGDDCKEINEALSLPL
NTEFAEWKLEVAVDRLVAHGFSVEAKRKAFPKQRFFDIGALIYYLRAIPWQAPGFSVERHLPQLDHISQEIKKNGYFETT
QHRFILKARK
>Mature_249_residues
AYSKTFLEQVETAMKQSFSGWNFEQLRGRVKEDELDWSYREWVKESLKQRTVLDMGTGGGEFLSSCAPFRGKVYATEGYE
PNVEIAQKALAPFGVSVRYIEDDDNLPFSDEAFDSIINRHESYSEQELARILKPGGTFITQQAGGDDCKEINEALSLPLN
TEFAEWKLEVAVDRLVAHGFSVEAKRKAFPKQRFFDIGALIYYLRAIPWQAPGFSVERHLPQLDHISQEIKKNGYFETTQ
HRFILKARK

Specific function: Specifically Methylates The Guanosine In Position 745 Of 23s rRNA. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.51 [C]

Molecular weight: Translated: 28706; Mature: 28574

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSKTFLEQVETAMKQSFSGWNFEQLRGRVKEDELDWSYREWVKESLKQRTVLDMGTGG
CCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
GEFLSSCAPFRGKVYATEGYEPNVEIAQKALAPFGVSVRYIEDDDNLPFSDEAFDSIINR
HHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHH
HESYSEQELARILKPGGTFITQQAGGDDCKEINEALSLPLNTEFAEWKLEVAVDRLVAHG
HHCCCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
FSVEAKRKAFPKQRFFDIGALIYYLRAIPWQAPGFSVERHLPQLDHISQEIKKNGYFETT
CCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHCCCEECC
QHRFILKARK
CCEEEEEECC
>Mature Secondary Structure 
AYSKTFLEQVETAMKQSFSGWNFEQLRGRVKEDELDWSYREWVKESLKQRTVLDMGTGG
CCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
GEFLSSCAPFRGKVYATEGYEPNVEIAQKALAPFGVSVRYIEDDDNLPFSDEAFDSIINR
HHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHH
HESYSEQELARILKPGGTFITQQAGGDDCKEINEALSLPLNTEFAEWKLEVAVDRLVAHG
HHCCCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
FSVEAKRKAFPKQRFFDIGALIYYLRAIPWQAPGFSVERHLPQLDHISQEIKKNGYFETT
CCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHCCCEECC
QHRFILKARK
CCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Unidentified protein factor B [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; rRNA [C]

Specific reaction: S-Adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

General reaction: Methyl group transfer [C]

Inhibitor: Mg2+; Unidentified protein factor A1 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA