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The map label for this gene is tyrA [H]

Identifier: 56963667

GI number: 56963667

Start: 2018877

End: 2019974

Strand: Direct

Name: tyrA [H]

Synonym: ABC1902

Alternate gene names: 56963667

Gene position: 2018877-2019974 (Clockwise)

Preceding gene: 56963666

Following gene: 56963668

Centisome position: 46.91

GC content: 46.54

Gene sequence:

>1098_bases
ATGAAGCGTACAGCATTTGTTGTCGGGATGGGGTTGATTGGCGGCTCCATCTCGCTTGCAATTAAGCGCGACCAAGACAT
CCATTTGGTTGGCTACGATATTTCAGCCGAACAGCTCCATATGGCTAAAGCACTTGGCGTAATTGATGAGGCTGCCTCAA
GCCTAGAAGAAGGGGCACAAGCAGCTGATTTTATCATTTTAGCAGTGCCAGTAAGCAAAACGATTGAATTGATTGAGCAG
CTTAGCACGATCCCGTTGAAACAAGGTGTCATCGTTACGGATGTCGGTTCAACAAAGCAAGATATTGCCGCGGCTGCTGA
TAACCATTTCGGTGACAACGTCTGCTTTATTGGCGGCCATCCGATGGCAGGGTCACATAAATCGGGCGTCGAGGCAGCAA
AAGCCCATTTGTTTGAAAATGCGTTTTACTTGCTAGCACCTGGCAAGAATAGTGAGCCACGCCATATTATCGCCTTGCAA
AATTTATTGAAAGGCACGAAAGCGCGTTTTTTGCAAATGGAACCACAACAGCATGACAAACTGGCAGGCACAGTGAGCCA
TTTCCCCCATATTATTGCAGCTAGCCTAGTCCATCAGCTCAAAAAGCTTGAAAAAACCGATCCAGAGGTAGCCCAATTAG
CGGCAGGCGGTTTCAGGGATATTACGCGGATTGCCTCGGCGAGCCCGGTCATGTGGCGTGATGTGCTTTTGCATAATAAA
GAAGAAATGCTGCGCCTATTTGCCGAATGGCAAATCGAGATGGATTCCGTAAAAGAAATGGTTGAACGCTGCGACGGCAA
AGCCATTCATGCTTACTTCCAAGAAGCAAAAGCATTCCGTGAAGAGTTGCCACAGCGCGAAAAAGGAGCGATACCGGCTT
TTTATGATTTGTTCGTCGATGTTCCTGACCATCCAGGCGTTATCTCCGATGTGACAAGGATACTTGCTAATAAAGAAATT
AGCATTACCAATATTCGAATATTAGAGACGCGGGAAGACATTATGGGCGTTTTGCGCCTTAGTTTCCGTTCAGAAGACGA
TCGAGTATATGCCCAGGAAGAACTGAAACGGCATATGTATGAAACTTACACGATATAA

Upstream 100 bases:

>100_bases
TGAGGCCGAAAATGATGCCTTTATAGAAAAAGCTCCTGAGATTTTGGACCAGCTCCGTGCAAGCTTAGGCGCATAAAAAG
AGTAGGAGAATAGTATTGAC

Downstream 100 bases:

>100_bases
GGAGAAGAAGTATGGACGAGACGATAAAGCTGCTAAACAAAGCAGAATCGGGTTTGTCAGGGACAATTGTCGTACCTGGC
GATAAATCGATTTCACACCG

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: PDH [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MKRTAFVVGMGLIGGSISLAIKRDQDIHLVGYDISAEQLHMAKALGVIDEAASSLEEGAQAADFIILAVPVSKTIELIEQ
LSTIPLKQGVIVTDVGSTKQDIAAAADNHFGDNVCFIGGHPMAGSHKSGVEAAKAHLFENAFYLLAPGKNSEPRHIIALQ
NLLKGTKARFLQMEPQQHDKLAGTVSHFPHIIAASLVHQLKKLEKTDPEVAQLAAGGFRDITRIASASPVMWRDVLLHNK
EEMLRLFAEWQIEMDSVKEMVERCDGKAIHAYFQEAKAFREELPQREKGAIPAFYDLFVDVPDHPGVISDVTRILANKEI
SITNIRILETREDIMGVLRLSFRSEDDRVYAQEELKRHMYETYTI

Sequences:

>Translated_365_residues
MKRTAFVVGMGLIGGSISLAIKRDQDIHLVGYDISAEQLHMAKALGVIDEAASSLEEGAQAADFIILAVPVSKTIELIEQ
LSTIPLKQGVIVTDVGSTKQDIAAAADNHFGDNVCFIGGHPMAGSHKSGVEAAKAHLFENAFYLLAPGKNSEPRHIIALQ
NLLKGTKARFLQMEPQQHDKLAGTVSHFPHIIAASLVHQLKKLEKTDPEVAQLAAGGFRDITRIASASPVMWRDVLLHNK
EEMLRLFAEWQIEMDSVKEMVERCDGKAIHAYFQEAKAFREELPQREKGAIPAFYDLFVDVPDHPGVISDVTRILANKEI
SITNIRILETREDIMGVLRLSFRSEDDRVYAQEELKRHMYETYTI
>Mature_365_residues
MKRTAFVVGMGLIGGSISLAIKRDQDIHLVGYDISAEQLHMAKALGVIDEAASSLEEGAQAADFIILAVPVSKTIELIEQ
LSTIPLKQGVIVTDVGSTKQDIAAAADNHFGDNVCFIGGHPMAGSHKSGVEAAKAHLFENAFYLLAPGKNSEPRHIIALQ
NLLKGTKARFLQMEPQQHDKLAGTVSHFPHIIAASLVHQLKKLEKTDPEVAQLAAGGFRDITRIASASPVMWRDVLLHNK
EEMLRLFAEWQIEMDSVKEMVERCDGKAIHAYFQEAKAFREELPQREKGAIPAFYDLFVDVPDHPGVISDVTRILANKEI
SITNIRILETREDIMGVLRLSFRSEDDRVYAQEELKRHMYETYTI

Specific function: Unknown

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR002912
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF01842 ACT; PF02153 PDH [H]

EC number: =1.3.1.12 [H]

Molecular weight: Translated: 40514; Mature: 40514

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTAFVVGMGLIGGSISLAIKRDQDIHLVGYDISAEQLHMAKALGVIDEAASSLEEGAQ
CCCEEEEEEEEEECCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCH
AADFIILAVPVSKTIELIEQLSTIPLKQGVIVTDVGSTKQDIAAAADNHFGDNVCFIGGH
HHCEEEEEECHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCEEEECCC
PMAGSHKSGVEAAKAHLFENAFYLLAPGKNSEPRHIIALQNLLKGTKARFLQMEPQQHDK
CCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHEECCCHHHHH
LAGTVSHFPHIIAASLVHQLKKLEKTDPEVAQLAAGGFRDITRIASASPVMWRDVLLHNK
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCH
EEMLRLFAEWQIEMDSVKEMVERCDGKAIHAYFQEAKAFREELPQREKGAIPAFYDLFVD
HHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHEEE
VPDHPGVISDVTRILANKEISITNIRILETREDIMGVLRLSFRSEDDRVYAQEELKRHMY
CCCCCCHHHHHHHHHCCCCEEEEEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ETYTI
HHCCC
>Mature Secondary Structure
MKRTAFVVGMGLIGGSISLAIKRDQDIHLVGYDISAEQLHMAKALGVIDEAASSLEEGAQ
CCCEEEEEEEEEECCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCH
AADFIILAVPVSKTIELIEQLSTIPLKQGVIVTDVGSTKQDIAAAADNHFGDNVCFIGGH
HHCEEEEEECHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCEEEECCC
PMAGSHKSGVEAAKAHLFENAFYLLAPGKNSEPRHIIALQNLLKGTKARFLQMEPQQHDK
CCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHEECCCHHHHH
LAGTVSHFPHIIAASLVHQLKKLEKTDPEVAQLAAGGFRDITRIASASPVMWRDVLLHNK
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCH
EEMLRLFAEWQIEMDSVKEMVERCDGKAIHAYFQEAKAFREELPQREKGAIPAFYDLFVD
HHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHEEE
VPDHPGVISDVTRILANKEISITNIRILETREDIMGVLRLSFRSEDDRVYAQEELKRHMY
CCCCCCHHHHHHHHHCCCCEEEEEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ETYTI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3106153; 9384377 [H]