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The map label for this gene is ubiA [H]

Identifier: 56963652

GI number: 56963652

Start: 2004498

End: 2005385

Strand: Direct

Name: ubiA [H]

Synonym: ABC1887

Alternate gene names: 56963652

Gene position: 2004498-2005385 (Clockwise)

Preceding gene: 56963651

Following gene: 56963653

Centisome position: 46.57

GC content: 42.79

Gene sequence:

>888_bases
ATGGCTACTGCATCTTTAAATAAAACGAAAATCTTTTTGCGAATGATTAAATTTGAACATACAATTTTTGCATTGCCGTT
TGCATTCCTAGCAATGTTGCTTGGCAGTTTAATTGCCTACGGCCAGTTTCCTTCGTTGCTTCAGTGGCTTTGGGTGACAT
TGGCGATGGTCGGAGCAAGGAGTGCCGCGATGTCGCTTAACCGCGTCATAGACGCTAAGTTTGACCGTGAAAACCCTAGA
ACGGCTAACAGGGAGATACCAGCAGGGCTGTTATCGAAGGCGGATGTCTGGATTTTTATTGTCGCTTCTTTTGCACTATT
GTTTTTGGCTGCTTCGCAGTTGAATATTCTTTCCGTCTATTTGTTGCCAATTGCTGTATTCTTTCTTGTGTTTTATTCCT
ATACCAAACGTTTTACGTGGGCATGCCACTTAATTTTAGGGATAACGATCGGGATTGCGCCTTTAGGCGGATGGGTTGCT
GTAACTGGCCAGTTGCCATTGGCTAGCTTTTGTTTGTTTTTGGCTGTCATGTTTTGGCTTGCTGGTTTTGACACCGTGTA
TGCAACACAGGATGCTGAATACGATCAAACACACGGGCTCCATTCGATTCCAAGCCGTTTTGGCATCAAAAAAGCGTTAT
GGATCGCCCGTTGTTTTCATGTCGTCAGTTTTGCGTTTTTTGTTGGTCTCTACTTTTTAACGCCTTTGACATGGATTTAC
TTGGTGGGCGTCGCCCTTTCAGGAATGATTATGGTTTACCAGCATTTAATTGTTTCTGAGAAAGATTTATCGAAAGTGCA
ATTGGCGTTTTTTCCGATGAATGGGACGCTTAGTGTCGTCATGTTTTTATTTGCTTTTGCCGATATGCTTGTCATCCGGT
TTTATTAA

Upstream 100 bases:

>100_bases
GGATGTTACAGTAAAGAGCTACACAGGCGGTGTTTGCGCTATGCATATGGGGATAAAACCGATATAGAAATGTGTGATAT
TGGAGAGGAGTAAGGCAGTA

Downstream 100 bases:

>100_bases
AGGAGGTTCCTATGAGCTTACATGTTGGAGAAATTGCATATACCAACACATTGCCGTTTTTCTTCGAGCTGGACCGTAGC
TCATTAGAGCAACACGGCAT

Product: 4-hydroxybenzoate octaprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MATASLNKTKIFLRMIKFEHTIFALPFAFLAMLLGSLIAYGQFPSLLQWLWVTLAMVGARSAAMSLNRVIDAKFDRENPR
TANREIPAGLLSKADVWIFIVASFALLFLAASQLNILSVYLLPIAVFFLVFYSYTKRFTWACHLILGITIGIAPLGGWVA
VTGQLPLASFCLFLAVMFWLAGFDTVYATQDAEYDQTHGLHSIPSRFGIKKALWIARCFHVVSFAFFVGLYFLTPLTWIY
LVGVALSGMIMVYQHLIVSEKDLSKVQLAFFPMNGTLSVVMFLFAFADMLVIRFY

Sequences:

>Translated_295_residues
MATASLNKTKIFLRMIKFEHTIFALPFAFLAMLLGSLIAYGQFPSLLQWLWVTLAMVGARSAAMSLNRVIDAKFDRENPR
TANREIPAGLLSKADVWIFIVASFALLFLAASQLNILSVYLLPIAVFFLVFYSYTKRFTWACHLILGITIGIAPLGGWVA
VTGQLPLASFCLFLAVMFWLAGFDTVYATQDAEYDQTHGLHSIPSRFGIKKALWIARCFHVVSFAFFVGLYFLTPLTWIY
LVGVALSGMIMVYQHLIVSEKDLSKVQLAFFPMNGTLSVVMFLFAFADMLVIRFY
>Mature_294_residues
ATASLNKTKIFLRMIKFEHTIFALPFAFLAMLLGSLIAYGQFPSLLQWLWVTLAMVGARSAAMSLNRVIDAKFDRENPRT
ANREIPAGLLSKADVWIFIVASFALLFLAASQLNILSVYLLPIAVFFLVFYSYTKRFTWACHLILGITIGIAPLGGWVAV
TGQLPLASFCLFLAVMFWLAGFDTVYATQDAEYDQTHGLHSIPSRFGIKKALWIARCFHVVSFAFFVGLYFLTPLTWIYL
VGVALSGMIMVYQHLIVSEKDLSKVQLAFFPMNGTLSVVMFLFAFADMLVIRFY

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=215, Percent_Identity=28.8372093023256, Blast_Score=78, Evalue=8e-15,
Organism=Escherichia coli, GI1790473, Length=282, Percent_Identity=27.3049645390071, Blast_Score=85, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17553718, Length=248, Percent_Identity=27.8225806451613, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355567, Length=175, Percent_Identity=30.8571428571429, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 33157; Mature: 33026

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATASLNKTKIFLRMIKFEHTIFALPFAFLAMLLGSLIAYGQFPSLLQWLWVTLAMVGAR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SAAMSLNRVIDAKFDRENPRTANREIPAGLLSKADVWIFIVASFALLFLAASQLNILSVY
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLPIAVFFLVFYSYTKRFTWACHLILGITIGIAPLGGWVAVTGQLPLASFCLFLAVMFWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHH
AGFDTVYATQDAEYDQTHGLHSIPSRFGIKKALWIARCFHVVSFAFFVGLYFLTPLTWIY
HCCCHHEECCCCCCHHHCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGVALSGMIMVYQHLIVSEKDLSKVQLAFFPMNGTLSVVMFLFAFADMLVIRFY
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATASLNKTKIFLRMIKFEHTIFALPFAFLAMLLGSLIAYGQFPSLLQWLWVTLAMVGAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SAAMSLNRVIDAKFDRENPRTANREIPAGLLSKADVWIFIVASFALLFLAASQLNILSVY
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLPIAVFFLVFYSYTKRFTWACHLILGITIGIAPLGGWVAVTGQLPLASFCLFLAVMFWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHH
AGFDTVYATQDAEYDQTHGLHSIPSRFGIKKALWIARCFHVVSFAFFVGLYFLTPLTWIY
HCCCHHEECCCCCCHHHCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGVALSGMIMVYQHLIVSEKDLSKVQLAFFPMNGTLSVVMFLFAFADMLVIRFY
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA