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The map label for this gene is mecA1 [H]

Identifier: 56963623

GI number: 56963623

Start: 1974822

End: 1975424

Strand: Direct

Name: mecA1 [H]

Synonym: ABC1858

Alternate gene names: 56963623

Gene position: 1974822-1975424 (Clockwise)

Preceding gene: 56963622

Following gene: 56963624

Centisome position: 45.88

GC content: 42.45

Gene sequence:

>603_bases
ATGCGCTTAGAGCGTTTAGCAATCGATAAATTTAAGGTTTTTTTAACCTATGATGATATGGACGAAAGAGGGATTACAAA
AGAAGACTTGTGGCAAGATGTTCCGAAAGTCCATGACTTATTCCGGGATATGATGCTGGAAGCAGATGACGAGCTAGGTT
TTAAAATCGATGGGCCGATTGCGGTTGAAGTGTTTGCGATGCCAGCGCAGGGCATGGTCTTTATTATTACGAAAGGCGAC
CCTGCTGACGAGTATGATGCCGAAGACTATGAAGAAGGATTCATTGAAATGCAATTGACTTTAGACGAGACCGACGAAGT
TTTTTATGAATTTTCTTCGTTTGAAGATGTCATTGGTCTCGCATCTCGTCTACATGCCATTGACATGCTAGGCGGCGAAT
TGCATTCCTATCAAACGCGCTTCTACTTAAAGTTTAACGAAGCAGAGCTTGAAGAAGTGAATGAAGCAGCCCTTATAGCG
ATTTTATCAGAATTTGGCAGCCCGGCAACGACCTCTTTCCATCGTATTTGCGAATATGGAAAAGCGTTAATGCCGGCACA
AGCGATTGAACAGCTTTATCGGATTTTTTATCTGAAAACGTAG

Upstream 100 bases:

>100_bases
AGGAAAAATAATGATTTTGAGAACCATCTTTTGCGTATCCACATACCGTATCGTATAGATACGCGCGAGAGAACCATACG
GGCATAAAGGAGGGGCTGGT

Downstream 100 bases:

>100_bases
CTAGGTGTAGCGAAAGGCATGAAACCTTTCGCTGCTTTTTTCGTAAACAAAAATAACAAGTACTTGAGCGAAAAGCATCA
AACGAAATGAAACCTTGGTT

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MRLERLAIDKFKVFLTYDDMDERGITKEDLWQDVPKVHDLFRDMMLEADDELGFKIDGPIAVEVFAMPAQGMVFIITKGD
PADEYDAEDYEEGFIEMQLTLDETDEVFYEFSSFEDVIGLASRLHAIDMLGGELHSYQTRFYLKFNEAELEEVNEAALIA
ILSEFGSPATTSFHRICEYGKALMPAQAIEQLYRIFYLKT

Sequences:

>Translated_200_residues
MRLERLAIDKFKVFLTYDDMDERGITKEDLWQDVPKVHDLFRDMMLEADDELGFKIDGPIAVEVFAMPAQGMVFIITKGD
PADEYDAEDYEEGFIEMQLTLDETDEVFYEFSSFEDVIGLASRLHAIDMLGGELHSYQTRFYLKFNEAELEEVNEAALIA
ILSEFGSPATTSFHRICEYGKALMPAQAIEQLYRIFYLKT
>Mature_200_residues
MRLERLAIDKFKVFLTYDDMDERGITKEDLWQDVPKVHDLFRDMMLEADDELGFKIDGPIAVEVFAMPAQGMVFIITKGD
PADEYDAEDYEEGFIEMQLTLDETDEVFYEFSSFEDVIGLASRLHAIDMLGGELHSYQTRFYLKFNEAELEEVNEAALIA
ILSEFGSPATTSFHRICEYGKALMPAQAIEQLYRIFYLKT

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 23076; Mature: 23076

Theoretical pI: Translated: 4.00; Mature: 4.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLERLAIDKFKVFLTYDDMDERGITKEDLWQDVPKVHDLFRDMMLEADDELGFKIDGPI
CCCHHHHHEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCE
AVEVFAMPAQGMVFIITKGDPADEYDAEDYEEGFIEMQLTLDETDEVFYEFSSFEDVIGL
EEEEEEECCCCEEEEEECCCCCCCCCCCHHHCCEEEEEEEECCHHHHHHHHHHHHHHHHH
ASRLHAIDMLGGELHSYQTRFYLKFNEAELEEVNEAALIAILSEFGSPATTSFHRICEYG
HHHHHHHHHHCCHHHCEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
KALMPAQAIEQLYRIFYLKT
CCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLERLAIDKFKVFLTYDDMDERGITKEDLWQDVPKVHDLFRDMMLEADDELGFKIDGPI
CCCHHHHHEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCE
AVEVFAMPAQGMVFIITKGDPADEYDAEDYEEGFIEMQLTLDETDEVFYEFSSFEDVIGL
EEEEEEECCCCEEEEEECCCCCCCCCCCHHHCCEEEEEEEECCHHHHHHHHHHHHHHHHH
ASRLHAIDMLGGELHSYQTRFYLKFNEAELEEVNEAALIAILSEFGSPATTSFHRICEYG
HHHHHHHHHHCCHHHCEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
KALMPAQAIEQLYRIFYLKT
CCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]