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The map label for this gene is ycbL [H]

Identifier: 56963624

GI number: 56963624

Start: 1975563

End: 1976249

Strand: Direct

Name: ycbL [H]

Synonym: ABC1859

Alternate gene names: 56963624

Gene position: 1975563-1976249 (Clockwise)

Preceding gene: 56963623

Following gene: 56963625

Centisome position: 45.9

GC content: 44.1

Gene sequence:

>687_bases
ATGGCAATATTGTTAATCGAAGATGATCGATCAATTGCAACGATTGTGAAAGAGTATTTAGAGAGGGAATCCTTTAAAGT
CGTATGGCAAGCTGATGGGGAAAGCGGCTACCATGCCTTTTGTGAAGGTGCGTACCAGCTTGTATTAATCGATTTGATGC
TTCCGAAAATGGATGGGTTTGCTTTGTGTGAGAAAATTCGTGCCAGTTCAGAAGTGCCCATTATTGTTGTTAGTGCAAAG
CAAACTGATTTCGACAAAGTCCAAAGTTTCGGGTTAGGCGCAGACGACTATGTGACAAAGCCATTTAGCCCCCTTGAACT
AACGGCAAGGGTGAAAGCGCAAATTCGCCGTTATGAACGGTCGTACCCACAGCAAGAAGACAGGCTTCAATTTATAGATG
TAGAAATCGACATAAAAGGCAGGCGTGTTTTCGCCCGTGGCGAGCAGATTTCTCTTACAGCAAAAGAATTTGAACTGCTG
CTGTTTTTAGCCAACCACCCAGGGCGCGTTTTTACAAAAGAAGAGCTGTACGCAGCAGTATGGAATGGCGATGGCTTTGA
CAGCAGGACGGTTACAGTCCATGTGAAAAATGTCAGACACAAATTAAAAGACGGGACGAAGCATCCGAAATACATAGAAA
CGGTATGGGGCGTTGGTTATAAATTTATAGGACTTGGGAACCGATGA

Upstream 100 bases:

>100_bases
TTTCGTAAACAAAAATAACAAGTACTTGAGCGAAAAGCATCAAACGAAATGAAACCTTGGTTTGATAAGGGGTAGCATTT
TAGGAGTGTGAGAACGGTTT

Downstream 100 bases:

>100_bases
AGCTTAGGGGGCAGTTAAACTTGCTCTTGCTCGCAACCGCGCTTGTCCCGTTTATCGCGACAAGCTTATTTTCATACCAA
CTAAACCGTGTGGCGAAAGA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MAILLIEDDRSIATIVKEYLERESFKVVWQADGESGYHAFCEGAYQLVLIDLMLPKMDGFALCEKIRASSEVPIIVVSAK
QTDFDKVQSFGLGADDYVTKPFSPLELTARVKAQIRRYERSYPQQEDRLQFIDVEIDIKGRRVFARGEQISLTAKEFELL
LFLANHPGRVFTKEELYAAVWNGDGFDSRTVTVHVKNVRHKLKDGTKHPKYIETVWGVGYKFIGLGNR

Sequences:

>Translated_228_residues
MAILLIEDDRSIATIVKEYLERESFKVVWQADGESGYHAFCEGAYQLVLIDLMLPKMDGFALCEKIRASSEVPIIVVSAK
QTDFDKVQSFGLGADDYVTKPFSPLELTARVKAQIRRYERSYPQQEDRLQFIDVEIDIKGRRVFARGEQISLTAKEFELL
LFLANHPGRVFTKEELYAAVWNGDGFDSRTVTVHVKNVRHKLKDGTKHPKYIETVWGVGYKFIGLGNR
>Mature_227_residues
AILLIEDDRSIATIVKEYLERESFKVVWQADGESGYHAFCEGAYQLVLIDLMLPKMDGFALCEKIRASSEVPIIVVSAKQ
TDFDKVQSFGLGADDYVTKPFSPLELTARVKAQIRRYERSYPQQEDRLQFIDVEIDIKGRRVFARGEQISLTAKEFELLL
FLANHPGRVFTKEELYAAVWNGDGFDSRTVTVHVKNVRHKLKDGTKHPKYIETVWGVGYKFIGLGNR

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=32.618025751073, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=35.8744394618834, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=35.2678571428571, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=33.6283185840708, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=31.5555555555556, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=34.6491228070175, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=35.2422907488987, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=29.6943231441048, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=32.0175438596491, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=31.858407079646, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=30.7359307359307, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1787229, Length=207, Percent_Identity=29.4685990338164, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=29.3333333333333, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26068; Mature: 25937

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILLIEDDRSIATIVKEYLERESFKVVWQADGESGYHAFCEGAYQLVLIDLMLPKMDGF
CEEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHEEEEEHHHCCCCHH
ALCEKIRASSEVPIIVVSAKQTDFDKVQSFGLGADDYVTKPFSPLELTARVKAQIRRYER
HHHHHHHCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SYPQQEDRLQFIDVEIDIKGRRVFARGEQISLTAKEFELLLFLANHPGRVFTKEELYAAV
CCCCCCCCEEEEEEEEEEECCEEEECCCEEEEEHHHEEEEEEEECCCCCEEEHHHEEEEE
WNGDGFDSRTVTVHVKNVRHKLKDGTKHPKYIETVWGVGYKFIGLGNR
ECCCCCCCEEEEEEEHHHHHHHHCCCCCCHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure 
AILLIEDDRSIATIVKEYLERESFKVVWQADGESGYHAFCEGAYQLVLIDLMLPKMDGF
EEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHEEEEEHHHCCCCHH
ALCEKIRASSEVPIIVVSAKQTDFDKVQSFGLGADDYVTKPFSPLELTARVKAQIRRYER
HHHHHHHCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SYPQQEDRLQFIDVEIDIKGRRVFARGEQISLTAKEFELLLFLANHPGRVFTKEELYAAV
CCCCCCCCEEEEEEEEEEECCEEEECCCEEEEEHHHEEEEEEEECCCCCEEEHHHEEEEE
WNGDGFDSRTVTVHVKNVRHKLKDGTKHPKYIETVWGVGYKFIGLGNR
ECCCCCCCEEEEEEEHHHHHHHHCCCCCCHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]