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The map label for this gene is resA

Identifier: 56963597

GI number: 56963597

Start: 1948541

End: 1949074

Strand: Direct

Name: resA

Synonym: ABC1832

Alternate gene names: 56963597

Gene position: 1948541-1949074 (Clockwise)

Preceding gene: 56963596

Following gene: 56963598

Centisome position: 45.27

GC content: 46.63

Gene sequence:

>534_bases
TTGGGTAAAAGCAAAAAGAAAAGGAGCATTATCCGTTTTACGGTGTTATTTGCAATCGTGTGTGCAATTGGCTACACGAT
TTATGCGAATGCCGCCTCTGAACAGGGAGCAGTTAAAGTCGGAGAACCGGCGACCAACTTTGCGTTAGTCGATCTGGAAC
AGGAGCGGTTTGAGCTTGGCCAAAATCAAGGCAAAGGTGTATTTATTAACTTTTGGGGCACGTTCTGTGAGCCGTGCGAG
CGGGAAATGCCTTACATTGAAAATGCATATGAGCAATACAAAGACGAAGTTGAAATGATTGCCGTTAATGTTGATGAGGC
GCCCCTAACGGTCCAGTCATTTATCAATCGCCATGGCCTTACTTTTCCAGTCGCCATTGATGAGCGCCGGGAAGTAACAC
GGGCGTATGGAATCGGCCCGCTTCCAGCTACAATTTTAGTGGACGAGCACGGCATTGTGCAAAAAGTACATACAGGCGCA
ATGACAGAGGAAATGGTCCACGAATTTTTCCAAAGCATTGTTCCTGACGCATAA

Upstream 100 bases:

>100_bases
GGCTGTCACGAAACCGTCATAAAATTGCAGGCGGACAAAACGAAGAAAGCGCTATAATGTAAGAAAACGTTCACATTTTC
GCGAGAGGAGGGGACGTCGC

Downstream 100 bases:

>100_bases
GGGCATCTGGGGGGATTTGTCATGAACGAACAGACGCACGTATGTGAGTGCGGACACAAAAACAGAGAAGGCACCGAGAT
GTGCGCTGCATGTGGGAAGC

Product: thiol-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MGKSKKKRSIIRFTVLFAIVCAIGYTIYANAASEQGAVKVGEPATNFALVDLEQERFELGQNQGKGVFINFWGTFCEPCE
REMPYIENAYEQYKDEVEMIAVNVDEAPLTVQSFINRHGLTFPVAIDERREVTRAYGIGPLPATILVDEHGIVQKVHTGA
MTEEMVHEFFQSIVPDA

Sequences:

>Translated_177_residues
MGKSKKKRSIIRFTVLFAIVCAIGYTIYANAASEQGAVKVGEPATNFALVDLEQERFELGQNQGKGVFINFWGTFCEPCE
REMPYIENAYEQYKDEVEMIAVNVDEAPLTVQSFINRHGLTFPVAIDERREVTRAYGIGPLPATILVDEHGIVQKVHTGA
MTEEMVHEFFQSIVPDA
>Mature_176_residues
GKSKKKRSIIRFTVLFAIVCAIGYTIYANAASEQGAVKVGEPATNFALVDLEQERFELGQNQGKGVFINFWGTFCEPCER
EMPYIENAYEQYKDEVEMIAVNVDEAPLTVQSFINRHGLTFPVAIDERREVTRAYGIGPLPATILVDEHGIVQKVHTGAM
TEEMVHEFFQSIVPDA

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RESA_BACSK (Q5WGY8)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175328.1
- HSSP:   P35160
- ProteinModelPortal:   Q5WGY8
- SMR:   Q5WGY8
- STRING:   Q5WGY8
- EnsemblBacteria:   EBBACT00000047454
- GeneID:   3201503
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1832
- NMPDR:   fig|66692.3.peg.1793
- eggNOG:   COG0526
- GeneTree:   EBGT00050000000761
- HOGENOM:   HBG493509
- OMA:   GTFCEPC
- ProtClustDB:   PRK03147
- BioCyc:   BCLA66692:ABC1832-MONOMER
- HAMAP:   MF_01319
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF08534 Redoxin; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 19836; Mature: 19705

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00194 THIOREDOXIN_1; PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1d792a30)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKSKKKRSIIRFTVLFAIVCAIGYTIYANAASEQGAVKVGEPATNFALVDLEQERFELG
CCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEECCCCCCEEEEECHHHHHHCC
QNQGKGVFINFWGTFCEPCEREMPYIENAYEQYKDEVEMIAVNVDEAPLTVQSFINRHGL
CCCCCEEEEEECCHHCCHHHCCCCHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHCCC
TFPVAIDERREVTRAYGIGPLPATILVDEHGIVQKVHTGAMTEEMVHEFFQSIVPDA
EEEEEECHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
GKSKKKRSIIRFTVLFAIVCAIGYTIYANAASEQGAVKVGEPATNFALVDLEQERFELG
CCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEECCCCCCEEEEECHHHHHHCC
QNQGKGVFINFWGTFCEPCEREMPYIENAYEQYKDEVEMIAVNVDEAPLTVQSFINRHGL
CCCCCEEEEEECCHHCCHHHCCCCHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHCCC
TFPVAIDERREVTRAYGIGPLPATILVDEHGIVQKVHTGAMTEEMVHEFFQSIVPDA
EEEEEECHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA