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The map label for this gene is asnO [H]

Identifier: 56963533

GI number: 56963533

Start: 1889458

End: 1891308

Strand: Direct

Name: asnO [H]

Synonym: ABC1768

Alternate gene names: 56963533

Gene position: 1889458-1891308 (Clockwise)

Preceding gene: 56963528

Following gene: 56963534

Centisome position: 43.9

GC content: 46.25

Gene sequence:

>1851_bases
ATGTGTGGCATTACTGGGTGGGTTGACTGGCAAAGAAACCTACGCACGGAAACGAAACAGATGAAAAATATGGCAAACAC
GCTGAATCGGCGCGGCCCTGATGCGCTCGAAACATGGACGTCCGACCACGCTGCGTTCGGGCATGCGCGGCTTGTCGTTG
TTGATCCAGAGGGCGGCAAACAGCCGATGACCCGCACTGCTAAAGGCAATACATGTACAATCGTGTACAATGGCGAACTA
TACAACACAGAAGAGCTACGCAAAGAACTTCTTGCCCATGGGCACACATTTGCTGGCCATTCAGATACGGAAGTGTTACT
TAAAGCGTATATGGAGTGGGGAGCCGCATGCCTTGAAAAATTGAATGGCATTTTTGCGTTTGCTGTTTGGGATGAACAAG
AACAAACATTATTTATGGCAAGGGATCGCCTTGGTGTTAAGCCGCTATTTTATACAGAAAAGGATGGCATGCTTCTCTTT
GGATCAGAACTTAAAGCGTTGCTGGCCCACTCGCAAATCGAAGCGGTTGTTGACCGTAGCGGATTAGCTGACGTGATGGG
GCTTTCACCTTCACGGACGCCAGGCCACGGTATTTTTAAAGGAATTGTCGAGTTGCGTCCGGCCCATTACTTGCAATTTA
GTAAAAATGGTTCCGCAGTAAAACGTTATTGGCAATTGCAAAGCAATATCCATACAGAAACGGCACATGAAACCGCTGCT
CACATTCGTGAACTTTTGGAAGATATTGTTGAGCGCCAGCTTTTTGCTGACGTTCCCGTTGGCATGTTTTTGTCAGGGGG
TGTCGATTCTAGCGCGTTAACGGCAATCGCTGCACGCATCTACGAAAAGCAAGGGAACGCTCCGATTTTTAGTTATTCCA
TTGACTATGAGGAAAATGAAAAATATTTTAAGGCAAGTACCTTTCAGCCAAATGCCGATGCCGATTGGGTAGAAAAAGTC
GCAGCTCATTGCGGCACCAACCATAAAAATTGCATTATCGGCAACGATGTCCTGGCCAATTTGCTAAAAGAATCTGTCCT
TGTAAGGGATACACCGGGAATGGCCGACGTCGACTCATCCTTGTTGTGGTTTTGTAAGCAAATTAAAAATGATGTGACTG
TTGGTTTGTCCGGGGAGTGCGCTGATGAAATATTCGGTGGCTATCCATGGTTCCATAAAGCAGAAGTGATGGCCATAGAC
GGTTTTCCTTGGATGCGCTCGCTTGATGAACGGATTCAATTGTTGCAGCCTGATTGGCAGAAACGCCTTAATCTCCAGGA
ATACGTGTATGATCGTTATAAAGAAACGATTCAAGAAACACCGCGGTTTGACGGAGATTCTCCTGAGGAAGCTAGGCGGA
GGGAAATTTCTTACTTAAATATGATTTGGTTTATGACAAACTTGCTAGACCGCAAAGACCGGATGAGTATGGGCGCTTCC
CTTGAAGTCAGGGTTCCTTTTTCAGACCATCGCTTAGTCGAGTATGTGTGGAACATTCCTTGGGAGATGAAAACATATGG
GGGCAGAGAAAAGGGGATACTACGCAAAGCATTGCAAGGATTGCTCCCTGACGATGTACTCTTCCGGAAAAAAAGCCCTT
ACCCGAAAACCCATCATCCTTTATATACGGCGGCCGTAACAAAGGCGATCCAGGAAGTCGTTCGCCAAAAGGACGCACCA
TTGTTCACTTTTATTAACCGCGATCGCCTTAAAGAAATTGCAGATAAAGGTGGTTTCGACACAGGGAAACCTTATTTTGG
CCAATTAATGGCAGGGCCACAACTCCTTGCCCATTTTGTCCAAATCGATTACTGGATGAAGGCATACAACATTCAAATTG
ATGAATCGTGA

Upstream 100 bases:

>100_bases
GAAGCACTTTTGTGATTTGGGCTGAATACGATAGGTTAGGAGTGAAGGGATAGGTAAGGCTGAGGTTTTACTTACTTCCT
AGAAAGGGCTGATGGAATCG

Downstream 100 bases:

>100_bases
GTACTTCGCTCAGTAAAGCGCTCATTGGGAGTGCTTGTGCCAGCGAAACGGAAGCAAAGCAAGTGCATGCAGGTTAAGGT
CACAGTCTAGCCTCCTGCCC

Product: asparagine synthetase, glutamine-hydrolyzing

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MCGITGWVDWQRNLRTETKQMKNMANTLNRRGPDALETWTSDHAAFGHARLVVVDPEGGKQPMTRTAKGNTCTIVYNGEL
YNTEELRKELLAHGHTFAGHSDTEVLLKAYMEWGAACLEKLNGIFAFAVWDEQEQTLFMARDRLGVKPLFYTEKDGMLLF
GSELKALLAHSQIEAVVDRSGLADVMGLSPSRTPGHGIFKGIVELRPAHYLQFSKNGSAVKRYWQLQSNIHTETAHETAA
HIRELLEDIVERQLFADVPVGMFLSGGVDSSALTAIAARIYEKQGNAPIFSYSIDYEENEKYFKASTFQPNADADWVEKV
AAHCGTNHKNCIIGNDVLANLLKESVLVRDTPGMADVDSSLLWFCKQIKNDVTVGLSGECADEIFGGYPWFHKAEVMAID
GFPWMRSLDERIQLLQPDWQKRLNLQEYVYDRYKETIQETPRFDGDSPEEARRREISYLNMIWFMTNLLDRKDRMSMGAS
LEVRVPFSDHRLVEYVWNIPWEMKTYGGREKGILRKALQGLLPDDVLFRKKSPYPKTHHPLYTAAVTKAIQEVVRQKDAP
LFTFINRDRLKEIADKGGFDTGKPYFGQLMAGPQLLAHFVQIDYWMKAYNIQIDES

Sequences:

>Translated_616_residues
MCGITGWVDWQRNLRTETKQMKNMANTLNRRGPDALETWTSDHAAFGHARLVVVDPEGGKQPMTRTAKGNTCTIVYNGEL
YNTEELRKELLAHGHTFAGHSDTEVLLKAYMEWGAACLEKLNGIFAFAVWDEQEQTLFMARDRLGVKPLFYTEKDGMLLF
GSELKALLAHSQIEAVVDRSGLADVMGLSPSRTPGHGIFKGIVELRPAHYLQFSKNGSAVKRYWQLQSNIHTETAHETAA
HIRELLEDIVERQLFADVPVGMFLSGGVDSSALTAIAARIYEKQGNAPIFSYSIDYEENEKYFKASTFQPNADADWVEKV
AAHCGTNHKNCIIGNDVLANLLKESVLVRDTPGMADVDSSLLWFCKQIKNDVTVGLSGECADEIFGGYPWFHKAEVMAID
GFPWMRSLDERIQLLQPDWQKRLNLQEYVYDRYKETIQETPRFDGDSPEEARRREISYLNMIWFMTNLLDRKDRMSMGAS
LEVRVPFSDHRLVEYVWNIPWEMKTYGGREKGILRKALQGLLPDDVLFRKKSPYPKTHHPLYTAAVTKAIQEVVRQKDAP
LFTFINRDRLKEIADKGGFDTGKPYFGQLMAGPQLLAHFVQIDYWMKAYNIQIDES
>Mature_616_residues
MCGITGWVDWQRNLRTETKQMKNMANTLNRRGPDALETWTSDHAAFGHARLVVVDPEGGKQPMTRTAKGNTCTIVYNGEL
YNTEELRKELLAHGHTFAGHSDTEVLLKAYMEWGAACLEKLNGIFAFAVWDEQEQTLFMARDRLGVKPLFYTEKDGMLLF
GSELKALLAHSQIEAVVDRSGLADVMGLSPSRTPGHGIFKGIVELRPAHYLQFSKNGSAVKRYWQLQSNIHTETAHETAA
HIRELLEDIVERQLFADVPVGMFLSGGVDSSALTAIAARIYEKQGNAPIFSYSIDYEENEKYFKASTFQPNADADWVEKV
AAHCGTNHKNCIIGNDVLANLLKESVLVRDTPGMADVDSSLLWFCKQIKNDVTVGLSGECADEIFGGYPWFHKAEVMAID
GFPWMRSLDERIQLLQPDWQKRLNLQEYVYDRYKETIQETPRFDGDSPEEARRREISYLNMIWFMTNLLDRKDRMSMGAS
LEVRVPFSDHRLVEYVWNIPWEMKTYGGREKGILRKALQGLLPDDVLFRKKSPYPKTHHPLYTAAVTKAIQEVVRQKDAP
LFTFINRDRLKEIADKGGFDTGKPYFGQLMAGPQLLAHFVQIDYWMKAYNIQIDES

Specific function: Asparagine synthetase involved in sporulation [H]

COG id: COG0367

COG function: function code E; Asparagine synthase (glutamine-hydrolyzing)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI168229248, Length=571, Percent_Identity=26.2697022767075, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI168229252, Length=571, Percent_Identity=26.2697022767075, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI168229250, Length=571, Percent_Identity=26.2697022767075, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI296010848, Length=544, Percent_Identity=26.4705882352941, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI296010852, Length=467, Percent_Identity=25.4817987152034, Blast_Score=116, Evalue=8e-26,
Organism=Homo sapiens, GI296010850, Length=467, Percent_Identity=25.4817987152034, Blast_Score=116, Evalue=8e-26,
Organism=Escherichia coli, GI1786889, Length=548, Percent_Identity=26.4598540145985, Blast_Score=155, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI25147557, Length=560, Percent_Identity=26.7857142857143, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71993933, Length=558, Percent_Identity=26.5232974910394, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17560178, Length=408, Percent_Identity=27.4509803921569, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25147560, Length=339, Percent_Identity=28.023598820059, Blast_Score=95, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6321563, Length=571, Percent_Identity=26.2697022767075, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6325403, Length=575, Percent_Identity=25.5652173913043, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI45553209, Length=525, Percent_Identity=27.6190476190476, Blast_Score=147, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006426
- InterPro:   IPR001962
- InterPro:   IPR017932
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00733 Asn_synthase [H]

EC number: =6.3.5.4 [H]

Molecular weight: Translated: 70173; Mature: 70173

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGITGWVDWQRNLRTETKQMKNMANTLNRRGPDALETWTSDHAAFGHARLVVVDPEGGK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEEEECCCCCC
QPMTRTAKGNTCTIVYNGELYNTEELRKELLAHGHTFAGHSDTEVLLKAYMEWGAACLEK
CCCCCCCCCCEEEEEECCCEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LNGIFAFAVWDEQEQTLFMARDRLGVKPLFYTEKDGMLLFGSELKALLAHSQIEAVVDRS
CCCEEEEEEECCCHHHHHHHHHCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHC
GLADVMGLSPSRTPGHGIFKGIVELRPAHYLQFSKNGSAVKRYWQLQSNIHTETAHETAA
CCHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
HIRELLEDIVERQLFADVPVGMFLSGGVDSSALTAIAARIYEKQGNAPIFSYSIDYEENE
HHHHHHHHHHHHHHHHCCCHHHEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
KYFKASTFQPNADADWVEKVAAHCGTNHKNCIIGNDVLANLLKESVLVRDTPGMADVDSS
CEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHEEEECCCCCCCHHHH
LLWFCKQIKNDVTVGLSGECADEIFGGYPWFHKAEVMAIDGFPWMRSLDERIQLLQPDWQ
HHHHHHHHCCCEEECCCCCHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHH
KRLNLQEYVYDRYKETIQETPRFDGDSPEEARRREISYLNMIWFMTNLLDRKDRMSMGAS
HHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LEVRVPFSDHRLVEYVWNIPWEMKTYGGREKGILRKALQGLLPDDVLFRKKSPYPKTHHP
EEEECCCCCCHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCC
LYTAAVTKAIQEVVRQKDAPLFTFINRDRLKEIADKGGFDTGKPYFGQLMAGPQLLAHFV
HHHHHHHHHHHHHHHHCCCCEEEHHCHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHH
QIDYWMKAYNIQIDES
HHHHHHEEEEEEECCC
>Mature Secondary Structure
MCGITGWVDWQRNLRTETKQMKNMANTLNRRGPDALETWTSDHAAFGHARLVVVDPEGGK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEEEECCCCCC
QPMTRTAKGNTCTIVYNGELYNTEELRKELLAHGHTFAGHSDTEVLLKAYMEWGAACLEK
CCCCCCCCCCEEEEEECCCEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LNGIFAFAVWDEQEQTLFMARDRLGVKPLFYTEKDGMLLFGSELKALLAHSQIEAVVDRS
CCCEEEEEEECCCHHHHHHHHHCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHC
GLADVMGLSPSRTPGHGIFKGIVELRPAHYLQFSKNGSAVKRYWQLQSNIHTETAHETAA
CCHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
HIRELLEDIVERQLFADVPVGMFLSGGVDSSALTAIAARIYEKQGNAPIFSYSIDYEENE
HHHHHHHHHHHHHHHHCCCHHHEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
KYFKASTFQPNADADWVEKVAAHCGTNHKNCIIGNDVLANLLKESVLVRDTPGMADVDSS
CEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHEEEECCCCCCCHHHH
LLWFCKQIKNDVTVGLSGECADEIFGGYPWFHKAEVMAIDGFPWMRSLDERIQLLQPDWQ
HHHHHHHHCCCEEECCCCCHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHH
KRLNLQEYVYDRYKETIQETPRFDGDSPEEARRREISYLNMIWFMTNLLDRKDRMSMGAS
HHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LEVRVPFSDHRLVEYVWNIPWEMKTYGGREKGILRKALQGLLPDDVLFRKKSPYPKTHHP
EEEECCCCCCHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCC
LYTAAVTKAIQEVVRQKDAPLFTFINRDRLKEIADKGGFDTGKPYFGQLMAGPQLLAHFV
HHHHHHHHHHHHHHHHCCCCEEEHHCHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHH
QIDYWMKAYNIQIDES
HHHHHHEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 10498721 [H]