Click here to switch to the map view.

The map label for this gene is cah [H]

Identifier: 56963534

GI number: 56963534

Start: 1891510

End: 1892463

Strand: Direct

Name: cah [H]

Synonym: ABC1769

Alternate gene names: 56963534

Gene position: 1891510-1892463 (Clockwise)

Preceding gene: 56963533

Following gene: 56963535

Centisome position: 43.95

GC content: 46.44

Gene sequence:

>954_bases
ATGCCATTAGTCGATATGCCGTTGCGCGAGTTGTTAGCTTATGAAGGAATAAACCCTAAACCAGCAGATTTTGACCAATA
CTGGAACCGGGCCAAAACGGAAATTGAAGCGATTGATCCCGAAGTCACTCTAGTCGAATCTTCTTTCCAGTGTTCGTTTG
CAAACTGTTACCATTTCTATTATCGAAGCGCTGGAAATGCAAAAATCCATGCGAAATACGTACAGCCAAAAGCAGGGGAG
AAGACGCCAGCAGTTTTTATGTTCCATGGGTATGGGGGGCGTTCAGCCGAATGGAGCAGCTTGTTAAATTATGTAGCGGC
GGGTTTTTCTGTTTTCTATATGGACGTGCGTGGACAAGGTGGAACTTCAGAGGATCCTGGGGGCGTAAGGGGGAATACAT
ATAGGGGCCACATTATTCGCGGCCTCGATGCCGGGCCAGACGCACTTTTTTACCGCAGCGTTTTCTTGGACACCGTCCAA
TTGGTTCGTGCTGCTAAAACATTGCCTCACATCGATAAAACACGGCTTATGGCCACAGGGTGGTCGCAAGGGGGCGCCTT
AACGCTTGCCTGTGCTGCCCTTGTTCCTGAAATCAAGCGTCTTGCTCCAGTATACCCGTTTTTAAGCGATTACAAGCGAG
TGTGGCAAATGGATTTAGCGGTTCGTTCGTATAAAGAATTGGCTGATTATTTCCGTTCATACGATCCGCAACATAAACGC
CATGGCGAAATTTTTGAACGCCTTGGCTACATCGATGTCCAGCATCTTGCTGACCGGATTCAAGGAGATGTCCTAATGGG
AGTTGGTTTAATGGATACAGAATGCCCGCCGTCTACCCAATTTGCTGCTTATAATAAAATAAAGGCTAAAAAATCGTATG
AGCTCTATCCTGATTTTGGCCATGAGCACCTTCCAGGAATGAACGATCATATTTTTCGCTTTTTCACTAGTTGA

Upstream 100 bases:

>100_bases
TGGTTTGCTTTTTGTGTACGAATACGAGTGTGGGTCACGCTTTTTGAACCCTTTGAAAATTGGTATACTATACATAAAAC
GAAAAAGGGAAGGGACGCTT

Downstream 100 bases:

>100_bases
ACGAAGTTGTTTTTCCCACTCCATTCATGGGCTGTCCAAGCTCTGCATATAAGTGGATGGAGGGGAGGCTTTGATCGTGA
ATGTCCGAATGTTAGGGCGG

Product: cephalosporin-C deacetylase

Products: NA

Alternate protein names: Acetyl xylan esterase [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MPLVDMPLRELLAYEGINPKPADFDQYWNRAKTEIEAIDPEVTLVESSFQCSFANCYHFYYRSAGNAKIHAKYVQPKAGE
KTPAVFMFHGYGGRSAEWSSLLNYVAAGFSVFYMDVRGQGGTSEDPGGVRGNTYRGHIIRGLDAGPDALFYRSVFLDTVQ
LVRAAKTLPHIDKTRLMATGWSQGGALTLACAALVPEIKRLAPVYPFLSDYKRVWQMDLAVRSYKELADYFRSYDPQHKR
HGEIFERLGYIDVQHLADRIQGDVLMGVGLMDTECPPSTQFAAYNKIKAKKSYELYPDFGHEHLPGMNDHIFRFFTS

Sequences:

>Translated_317_residues
MPLVDMPLRELLAYEGINPKPADFDQYWNRAKTEIEAIDPEVTLVESSFQCSFANCYHFYYRSAGNAKIHAKYVQPKAGE
KTPAVFMFHGYGGRSAEWSSLLNYVAAGFSVFYMDVRGQGGTSEDPGGVRGNTYRGHIIRGLDAGPDALFYRSVFLDTVQ
LVRAAKTLPHIDKTRLMATGWSQGGALTLACAALVPEIKRLAPVYPFLSDYKRVWQMDLAVRSYKELADYFRSYDPQHKR
HGEIFERLGYIDVQHLADRIQGDVLMGVGLMDTECPPSTQFAAYNKIKAKKSYELYPDFGHEHLPGMNDHIFRFFTS
>Mature_316_residues
PLVDMPLRELLAYEGINPKPADFDQYWNRAKTEIEAIDPEVTLVESSFQCSFANCYHFYYRSAGNAKIHAKYVQPKAGEK
TPAVFMFHGYGGRSAEWSSLLNYVAAGFSVFYMDVRGQGGTSEDPGGVRGNTYRGHIIRGLDAGPDALFYRSVFLDTVQL
VRAAKTLPHIDKTRLMATGWSQGGALTLACAALVPEIKRLAPVYPFLSDYKRVWQMDLAVRSYKELADYFRSYDPQHKRH
GEIFERLGYIDVQHLADRIQGDVLMGVGLMDTECPPSTQFAAYNKIKAKKSYELYPDFGHEHLPGMNDHIFRFFTS

Specific function: Esterase that removed acetyl groups from a number of O- acetylated small substrates, such as acetylated xylose, short xylooligosaccharides and cephalosporin C. Has no activity towards polymeric acetylated xylan. Cannot cleave amide linkages [H]

COG id: COG3458

COG function: function code Q; Acetyl esterase (deacetylase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate esterase 7 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008391 [H]

Pfam domain/function: PF05448 AXE1 [H]

EC number: =3.1.1.41; =3.1.1.72 [H]

Molecular weight: Translated: 35870; Mature: 35739

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVDMPLRELLAYEGINPKPADFDQYWNRAKTEIEAIDPEVTLVESSFQCSFANCYHFY
CCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
YRSAGNAKIHAKYVQPKAGEKTPAVFMFHGYGGRSAEWSSLLNYVAAGFSVFYMDVRGQG
HHCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEEEECCC
GTSEDPGGVRGNTYRGHIIRGLDAGPDALFYRSVFLDTVQLVRAAKTLPHIDKTRLMATG
CCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEC
WSQGGALTLACAALVPEIKRLAPVYPFLSDYKRVWQMDLAVRSYKELADYFRSYDPQHKR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
HGEIFERLGYIDVQHLADRIQGDVLMGVGLMDTECPPSTQFAAYNKIKAKKSYELYPDFG
HHHHHHHHCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
HEHLPGMNDHIFRFFTS
CCCCCCCCHHHHHEECC
>Mature Secondary Structure 
PLVDMPLRELLAYEGINPKPADFDQYWNRAKTEIEAIDPEVTLVESSFQCSFANCYHFY
CCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
YRSAGNAKIHAKYVQPKAGEKTPAVFMFHGYGGRSAEWSSLLNYVAAGFSVFYMDVRGQG
HHCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEEEECCC
GTSEDPGGVRGNTYRGHIIRGLDAGPDALFYRSVFLDTVQLVRAAKTLPHIDKTRLMATG
CCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEC
WSQGGALTLACAALVPEIKRLAPVYPFLSDYKRVWQMDLAVRSYKELADYFRSYDPQHKR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
HGEIFERLGYIDVQHLADRIQGDVLMGVGLMDTECPPSTQFAAYNKIKAKKSYELYPDFG
HHHHHHHHCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
HEHLPGMNDHIFRFFTS
CCCCCCCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]