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The map label for this gene is udk [H]

Identifier: 56963363

GI number: 56963363

Start: 1722806

End: 1723450

Strand: Direct

Name: udk [H]

Synonym: ABC1598

Alternate gene names: 56963363

Gene position: 1722806-1723450 (Clockwise)

Preceding gene: 56963362

Following gene: 56963364

Centisome position: 40.03

GC content: 42.33

Gene sequence:

>645_bases
ATGGAATCAAGCATGAGGCCTGTGATCATTGGCGTAGCAGGCGGCACTGGATCTGGGAAGACAACGGTCGCCAAAGAAAT
ATTTAAGCAGTTCAGCCAGTCATCCATTGTCTTGATTGAACAAGATGCATATTATAAAAATCAAGATCATCTCACATTTG
AAGAGCGTTTAAAAACGAATTATGACCATCCGCTTTCATTTGACAATGAGCTTCTTTATGCCCATCTTATGCAACTGGCC
GATCGGTCGCCGATTTTTAAGCCTTCCTACGATTATGCCAATCATACACGGGCAAAAGAGGTTACAAAAATTGAGCCGAA
AGATGTCATTATCCTAGAAGGAATTTTGATTCTTGAAGACGAACGTTTACGAAGCATGATGGATATAAAGGTGTTTGTCG
ACACGGATCCTGATATCCGCATCATTCGTAGGCTTGTTCGCGATACAAAGGAGCGCGGGCGGTCAATTGATTCAGTCATT
GACCAATATACTTCGGTCGTGAGGCCCATGCATTTGCAGTTTGTGGAGCCGACAAAACGTTATGCCGATTTAATTATCCC
AGAAGGCGGGCAAAACAAAGTCGCGATCGATTTAATGGCAACAAAAATTCGCACAATTATTGAACAAAAGAAGTTGGATG
CTTAA

Upstream 100 bases:

>100_bases
CAACCATCCCGATTTTACGACGCGCATTTTGCCAATTGGCGATGGAATGGCGTGCAGCATGAAGATACGAACTTAACAGC
AACATAGGAGAGGAAGACGA

Downstream 100 bases:

>100_bases
AAAAAGCCAGTCCCAACCGTCCTTTTGTATATATTAATGAGGAGTGAATAGCATGGCAGAAGAGAAAAAACATTACATGA
CCGCAGAAGGCAAGAAAAAA

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MESSMRPVIIGVAGGTGSGKTTVAKEIFKQFSQSSIVLIEQDAYYKNQDHLTFEERLKTNYDHPLSFDNELLYAHLMQLA
DRSPIFKPSYDYANHTRAKEVTKIEPKDVIILEGILILEDERLRSMMDIKVFVDTDPDIRIIRRLVRDTKERGRSIDSVI
DQYTSVVRPMHLQFVEPTKRYADLIIPEGGQNKVAIDLMATKIRTIIEQKKLDA

Sequences:

>Translated_214_residues
MESSMRPVIIGVAGGTGSGKTTVAKEIFKQFSQSSIVLIEQDAYYKNQDHLTFEERLKTNYDHPLSFDNELLYAHLMQLA
DRSPIFKPSYDYANHTRAKEVTKIEPKDVIILEGILILEDERLRSMMDIKVFVDTDPDIRIIRRLVRDTKERGRSIDSVI
DQYTSVVRPMHLQFVEPTKRYADLIIPEGGQNKVAIDLMATKIRTIIEQKKLDA
>Mature_214_residues
MESSMRPVIIGVAGGTGSGKTTVAKEIFKQFSQSSIVLIEQDAYYKNQDHLTFEERLKTNYDHPLSFDNELLYAHLMQLA
DRSPIFKPSYDYANHTRAKEVTKIEPKDVIILEGILILEDERLRSMMDIKVFVDTDPDIRIIRRLVRDTKERGRSIDSVI
DQYTSVVRPMHLQFVEPTKRYADLIIPEGGQNKVAIDLMATKIRTIIEQKKLDA

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI13899253, Length=214, Percent_Identity=40.1869158878505, Blast_Score=173, Evalue=1e-43,
Organism=Homo sapiens, GI18699734, Length=213, Percent_Identity=38.9671361502347, Blast_Score=171, Evalue=3e-43,
Organism=Homo sapiens, GI301129207, Length=205, Percent_Identity=40.4878048780488, Blast_Score=168, Evalue=4e-42,
Organism=Homo sapiens, GI57863312, Length=205, Percent_Identity=40.4878048780488, Blast_Score=167, Evalue=5e-42,
Organism=Homo sapiens, GI209863022, Length=151, Percent_Identity=38.4105960264901, Blast_Score=118, Evalue=5e-27,
Organism=Escherichia coli, GI87082034, Length=211, Percent_Identity=51.1848341232227, Blast_Score=223, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI17539894, Length=209, Percent_Identity=38.755980861244, Blast_Score=170, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17539892, Length=209, Percent_Identity=38.755980861244, Blast_Score=169, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI71981181, Length=218, Percent_Identity=36.2385321100917, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6324339, Length=197, Percent_Identity=33.502538071066, Blast_Score=113, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6320223, Length=192, Percent_Identity=26.0416666666667, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221458995, Length=217, Percent_Identity=41.9354838709677, Blast_Score=174, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24649624, Length=214, Percent_Identity=42.5233644859813, Blast_Score=171, Evalue=2e-43,
Organism=Drosophila melanogaster, GI28573516, Length=206, Percent_Identity=38.8349514563107, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI28573514, Length=206, Percent_Identity=38.8349514563107, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI28573512, Length=206, Percent_Identity=38.8349514563107, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI45550449, Length=206, Percent_Identity=38.8349514563107, Blast_Score=166, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 24614; Mature: 24614

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00227 TUBULIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESSMRPVIIGVAGGTGSGKTTVAKEIFKQFSQSSIVLIEQDAYYKNQDHLTFEERLKTN
CCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHCC
YDHPLSFDNELLYAHLMQLADRSPIFKPSYDYANHTRAKEVTKIEPKDVIILEGILILED
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECEEEECC
ERLRSMMDIKVFVDTDPDIRIIRRLVRDTKERGRSIDSVIDQYTSVVRPMHLQFVEPTKR
HHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHEEECHHHH
YADLIIPEGGQNKVAIDLMATKIRTIIEQKKLDA
HHHEECCCCCCCCEEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MESSMRPVIIGVAGGTGSGKTTVAKEIFKQFSQSSIVLIEQDAYYKNQDHLTFEERLKTN
CCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHCC
YDHPLSFDNELLYAHLMQLADRSPIFKPSYDYANHTRAKEVTKIEPKDVIILEGILILED
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECEEEECC
ERLRSMMDIKVFVDTDPDIRIIRRLVRDTKERGRSIDSVIDQYTSVVRPMHLQFVEPTKR
HHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHEEECHHHH
YADLIIPEGGQNKVAIDLMATKIRTIIEQKKLDA
HHHEECCCCCCCCEEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]