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The map label for this gene is ruvB

Identifier: 56963320

GI number: 56963320

Start: 1678129

End: 1679130

Strand: Direct

Name: ruvB

Synonym: ABC1555

Alternate gene names: 56963320

Gene position: 1678129-1679130 (Clockwise)

Preceding gene: 56963319

Following gene: 56963321

Centisome position: 38.99

GC content: 52.1

Gene sequence:

>1002_bases
ATGGAAGAACGAATTGTTTCCGCTGAAGCAACGGAGTTGGAAGAACAGAGCGAGCAAGGGTTACGGCCAAAAAGATTGGC
CGATTATATCGGGCAAGAAACGGTTAAGCACAACCTTGCTGTGTTTATGGAGGCAGCAAAAATGCGCGAAGAAGCGCTTG
ACCATGTCCTGCTTTACGGACCGCCAGGCCTTGGGAAAACGACGCTAGCGGCGATTATTGCGGCGGAAATGGGCGGCGAG
TTGCGGACTACTTCCGGCCCGGCAATTGAGCGGTCTGGCGATTTGGCCGCGATTTTAACCGCCCTTGAGCCAGGAGACGT
TTTGTTTATTGATGAGATCCACCGCTTGAACCGCACAGTTGAAGAAGTGCTGTATCCGGCCATGGAAGATTTTTGTCTAG
ATATCGTCATTGGCAAAGGCCCAACTGCTAGATCGGTTCGATTAGATTTGCCGCCGTTTACGTTAGTGGGCGCGACAACA
CGTGCAGGAATGCTCTCGTCCCCGTTACGCGACCGTTTTGGCGTAATGGCAAGGCTTGAGTATTACAAACCTGAAGAACT
GGCTCAAATTGTGGAACGTTCCGCCACCGTTTTTCAAGCGACGCTTGAGCCGTCTGCAGCGCTTGAATTGGCGCGGCGGT
CAAGAGGGACTCCTCGGATTGCAAACCGCCTGCTCCGTCGCGTTCGTGATTTTGCCCAAGTAGGAGGGGAGGCTGCTATT
TCGTTGGAAAGGGCATGCTCCGCCCTTGAACAGCTCCATGTCGATCCGTTAGGGCTAGACCATATTGACGATAAATTGTT
AAAAGGCATGATTGAAAAATTTAATGGGGGCCCGGTTGGATTAGAAACGATTGCGGCGACCATTGGCGAAGAAGCGGCAA
CGATTGAGGAAGTATATGAGCCCTACTTGCTGCAAATTGGCTTTATCCAGCGGACGCCTCGGGGGCGGATAGCGACGCCG
GCTTGTTATGCTCATTATGGAGTGGAAAAGCAAAATGGGTAA

Upstream 100 bases:

>100_bases
AGTGGAAAAACAGTTAAAAGCGGAAACGCTGGAAACAGATGAATATATTAGGCGTGCGCTTGCGCTTATGTTAAAACGTC
CTTAAGTAAGGGGGATGACA

Downstream 100 bases:

>100_bases
AACATTAATGGTGATTGGCGCAGTGTTGCTCATTGTCGGTTTTCTTTGGCAAGTGTTGGGCCGCTTTTTGCCAATCGGCA
AATTGCCAGGGGATTTTTTG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MEERIVSAEATELEEQSEQGLRPKRLADYIGQETVKHNLAVFMEAAKMREEALDHVLLYGPPGLGKTTLAAIIAAEMGGE
LRTTSGPAIERSGDLAAILTALEPGDVLFIDEIHRLNRTVEEVLYPAMEDFCLDIVIGKGPTARSVRLDLPPFTLVGATT
RAGMLSSPLRDRFGVMARLEYYKPEELAQIVERSATVFQATLEPSAALELARRSRGTPRIANRLLRRVRDFAQVGGEAAI
SLERACSALEQLHVDPLGLDHIDDKLLKGMIEKFNGGPVGLETIAATIGEEAATIEEVYEPYLLQIGFIQRTPRGRIATP
ACYAHYGVEKQNG

Sequences:

>Translated_333_residues
MEERIVSAEATELEEQSEQGLRPKRLADYIGQETVKHNLAVFMEAAKMREEALDHVLLYGPPGLGKTTLAAIIAAEMGGE
LRTTSGPAIERSGDLAAILTALEPGDVLFIDEIHRLNRTVEEVLYPAMEDFCLDIVIGKGPTARSVRLDLPPFTLVGATT
RAGMLSSPLRDRFGVMARLEYYKPEELAQIVERSATVFQATLEPSAALELARRSRGTPRIANRLLRRVRDFAQVGGEAAI
SLERACSALEQLHVDPLGLDHIDDKLLKGMIEKFNGGPVGLETIAATIGEEAATIEEVYEPYLLQIGFIQRTPRGRIATP
ACYAHYGVEKQNG
>Mature_333_residues
MEERIVSAEATELEEQSEQGLRPKRLADYIGQETVKHNLAVFMEAAKMREEALDHVLLYGPPGLGKTTLAAIIAAEMGGE
LRTTSGPAIERSGDLAAILTALEPGDVLFIDEIHRLNRTVEEVLYPAMEDFCLDIVIGKGPTARSVRLDLPPFTLVGATT
RAGMLSSPLRDRFGVMARLEYYKPEELAQIVERSATVFQATLEPSAALELARRSRGTPRIANRLLRRVRDFAQVGGEAAI
SLERACSALEQLHVDPLGLDHIDDKLLKGMIEKFNGGPVGLETIAATIGEEAATIEEVYEPYLLQIGFIQRTPRGRIATP
ACYAHYGVEKQNG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=326, Percent_Identity=60.7361963190184, Blast_Score=410, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_BACSK (Q5WHR5)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175051.1
- ProteinModelPortal:   Q5WHR5
- SMR:   Q5WHR5
- STRING:   Q5WHR5
- EnsemblBacteria:   EBBACT00000047896
- GeneID:   3200664
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1555
- NMPDR:   fig|66692.3.peg.1517
- eggNOG:   COG2255
- GeneTree:   EBGT00050000000363
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   BCLA66692:ABC1555-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 36461; Mature: 36461

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEERIVSAEATELEEQSEQGLRPKRLADYIGQETVKHNLAVFMEAAKMREEALDHVLLYG
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEC
PPGLGKTTLAAIIAAEMGGELRTTSGPAIERSGDLAAILTALEPGDVLFIDEIHRLNRTV
CCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHH
EEVLYPAMEDFCLDIVIGKGPTARSVRLDLPPFTLVGATTRAGMLSSPLRDRFGVMARLE
HHHHHHHHHHHHEEEEECCCCCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
YYKPEELAQIVERSATVFQATLEPSAALELARRSRGTPRIANRLLRRVRDFAQVGGEAAI
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHH
SLERACSALEQLHVDPLGLDHIDDKLLKGMIEKFNGGPVGLETIAATIGEEAATIEEVYE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHH
PYLLQIGFIQRTPRGRIATPACYAHYGVEKQNG
HHHHHHHHHEECCCCCCCCCHHHHHCCCCCCCC
>Mature Secondary Structure
MEERIVSAEATELEEQSEQGLRPKRLADYIGQETVKHNLAVFMEAAKMREEALDHVLLYG
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEC
PPGLGKTTLAAIIAAEMGGELRTTSGPAIERSGDLAAILTALEPGDVLFIDEIHRLNRTV
CCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHH
EEVLYPAMEDFCLDIVIGKGPTARSVRLDLPPFTLVGATTRAGMLSSPLRDRFGVMARLE
HHHHHHHHHHHHEEEEECCCCCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
YYKPEELAQIVERSATVFQATLEPSAALELARRSRGTPRIANRLLRRVRDFAQVGGEAAI
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHH
SLERACSALEQLHVDPLGLDHIDDKLLKGMIEKFNGGPVGLETIAATIGEEAATIEEVYE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHH
PYLLQIGFIQRTPRGRIATPACYAHYGVEKQNG
HHHHHHHHHEECCCCCCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA