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The map label for this gene is ruvA

Identifier: 56963319

GI number: 56963319

Start: 1677514

End: 1678113

Strand: Direct

Name: ruvA

Synonym: ABC1554

Alternate gene names: 56963319

Gene position: 1677514-1678113 (Clockwise)

Preceding gene: 56963318

Following gene: 56963320

Centisome position: 38.98

GC content: 43.67

Gene sequence:

>600_bases
GTGATTGACTATATTAAAGGGAATTTGGTTGCAGTTGAACCTGCTTATCTCGTGGTCGAAGCCAACGGGATTGGGTTCCA
AATTTACTGTGCAAACCCTTACCGTTTTATAAACGATTTAAATCGGGAGGTAGTGGTCCCGACACACCACTATGTTCGCG
AAGACAGCCAACGCCTATTTGGGTTTACAACAAGGACAGAACGTTTGTTGTTTGAAAAGCTTTTAAATGTCTCTGGCATT
GGCCCAAAAGGAGCGCTCGCCATTCTTGCTTCTGGAGAACCAGAAGATATTATCCATGCAATTGAACAAGAAGATGAGGC
GCTGCTTGTCCGTTTCCCTGGAGTCGGCAAAAAAACAGCAAGACAAATCATTCTTGACTTAAAAGGGAAGCTTGATGATA
TGGCACCAATGCTGGAACCTGCTGCTGGCGCTGACAAACAGCAAAAAAATCCACAGCTTGAGGATGCTTTAGAAGCGTTG
CGTGCTTTGGGCTATGTTGAAAAAGAGCTGAAAAAAGTGGAAAAACAGTTAAAAGCGGAAACGCTGGAAACAGATGAATA
TATTAGGCGTGCGCTTGCGCTTATGTTAAAACGTCCTTAA

Upstream 100 bases:

>100_bases
CCCACTTGCTGGCTTAGTAGCAACTTAATGACGGAAAGCTATCTGCTATGCTAAAATAGAAATAAATGTTCGCTTTTTGG
CCATGCAGAGGAGAATGCTT

Downstream 100 bases:

>100_bases
GTAAGGGGGATGACAATGGAAGAACGAATTGTTTCCGCTGAAGCAACGGAGTTGGAAGAACAGAGCGAGCAAGGGTTACG
GCCAAAAAGATTGGCCGATT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MIDYIKGNLVAVEPAYLVVEANGIGFQIYCANPYRFINDLNREVVVPTHHYVREDSQRLFGFTTRTERLLFEKLLNVSGI
GPKGALAILASGEPEDIIHAIEQEDEALLVRFPGVGKKTARQIILDLKGKLDDMAPMLEPAAGADKQQKNPQLEDALEAL
RALGYVEKELKKVEKQLKAETLETDEYIRRALALMLKRP

Sequences:

>Translated_199_residues
MIDYIKGNLVAVEPAYLVVEANGIGFQIYCANPYRFINDLNREVVVPTHHYVREDSQRLFGFTTRTERLLFEKLLNVSGI
GPKGALAILASGEPEDIIHAIEQEDEALLVRFPGVGKKTARQIILDLKGKLDDMAPMLEPAAGADKQQKNPQLEDALEAL
RALGYVEKELKKVEKQLKAETLETDEYIRRALALMLKRP
>Mature_199_residues
MIDYIKGNLVAVEPAYLVVEANGIGFQIYCANPYRFINDLNREVVVPTHHYVREDSQRLFGFTTRTERLLFEKLLNVSGI
GPKGALAILASGEPEDIIHAIEQEDEALLVRFPGVGKKTARQIILDLKGKLDDMAPMLEPAAGADKQQKNPQLEDALEAL
RALGYVEKELKKVEKQLKAETLETDEYIRRALALMLKRP

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=199, Percent_Identity=32.1608040201005, Blast_Score=114, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_BACSK (Q5WHR6)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175050.1
- ProteinModelPortal:   Q5WHR6
- SMR:   Q5WHR6
- STRING:   Q5WHR6
- EnsemblBacteria:   EBBACT00000046896
- GeneID:   3200663
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1554
- NMPDR:   fig|66692.3.peg.1516
- eggNOG:   COG0632
- GeneTree:   EBGT00050000000364
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- ProtClustDB:   PRK00116
- BioCyc:   BCLA66692:ABC1554-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22357; Mature: 22357

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDYIKGNLVAVEPAYLVVEANGIGFQIYCANPYRFINDLNREVVVPTHHYVREDSQRLF
CCCEECCCEEEECCEEEEEEECCCEEEEEECCHHHHHHHCCCEEEECCHHHHHCCHHHHH
GFTTRTERLLFEKLLNVSGIGPKGALAILASGEPEDIIHAIEQEDEALLVRFPGVGKKTA
CCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEECCCCCHHHH
RQIILDLKGKLDDMAPMLEPAAGADKQQKNPQLEDALEALRALGYVEKELKKVEKQLKAE
HHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLETDEYIRRALALMLKRP
HCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDYIKGNLVAVEPAYLVVEANGIGFQIYCANPYRFINDLNREVVVPTHHYVREDSQRLF
CCCEECCCEEEECCEEEEEEECCCEEEEEECCHHHHHHHCCCEEEECCHHHHHCCHHHHH
GFTTRTERLLFEKLLNVSGIGPKGALAILASGEPEDIIHAIEQEDEALLVRFPGVGKKTA
CCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEECCCCCHHHH
RQIILDLKGKLDDMAPMLEPAAGADKQQKNPQLEDALEALRALGYVEKELKKVEKQLKAE
HHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLETDEYIRRALALMLKRP
HCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA