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The map label for this gene is ycgM [H]

Identifier: 56963258

GI number: 56963258

Start: 1613684

End: 1614319

Strand: Direct

Name: ycgM [H]

Synonym: ABC1493

Alternate gene names: 56963258

Gene position: 1613684-1614319 (Clockwise)

Preceding gene: 56963257

Following gene: 56963259

Centisome position: 37.49

GC content: 44.5

Gene sequence:

>636_bases
ATGGAGGAAATTGCGAGCATTTATTGCATTGGCCGTAACTATGCCAACCATGCGAAAGAATTAGGAAACGAAGTGCCGAC
AGAACCGTTGTTATTTGGCAAACCTAAAAGCGCAGCTGTGTTGGCTGACGGAAGGACGCTTCTTTATCCAAGTGACAAAG
GGGCCATCCATTATGAAGCCGAGATTGTATTGAAAATTGCCAAAGACATGGAGGATGGAGATACACTTGATGATGTCGTC
ACGGAGATGGCCATAGGTGTTGATTTAACGTTGCGAGACTTGCAAAGCAAGCTAAAGCAAAAAGGGCATCCTTGGCTCCG
CGCCAAAGGGTTTCGCAACTCTGCCATCCTAACGCCATTTTTCCCGTTTCCAGGCGAACAAGAAAGCAAAAGCCTCAACT
TTTCTCTCGAACGAAATGGCGAGGTCGTCCAGCTAGGCAATACGGAGAATATGTTGTTTTCGTTTAATGAAATTGTCCAA
GAATGCCATCTTACTTTTGGTTTAAAAAAGGGCGATTTGCTTTTTACAGGCACGCCAGAAGGTGTCGGGGCAATCGCTGA
TGGTGATCAATTTAACCTTGCATGTCAAGGAGAAACAAAGGGGACTTTTTTTGTGAGAATGGAAAGTAAAGAATAA

Upstream 100 bases:

>100_bases
ACGACATTGCGTGAGGCGATCGCACGAGTGGGCAACTTAAATCTGTTTTAATAAAACAATGAAACCGTGTCGTCCGTGTA
ATGACACAGAGGGGGATGGA

Downstream 100 bases:

>100_bases
ACACCTCCCTTTGTTTTTAAAACAAACCTTTGAAGAACGTAAACGGAAAGGAGGTGTATGGATGAAAACGTTGATTTATG
CCCACCGTGGTGCGTCTGGA

Product: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MEEIASIYCIGRNYANHAKELGNEVPTEPLLFGKPKSAAVLADGRTLLYPSDKGAIHYEAEIVLKIAKDMEDGDTLDDVV
TEMAIGVDLTLRDLQSKLKQKGHPWLRAKGFRNSAILTPFFPFPGEQESKSLNFSLERNGEVVQLGNTENMLFSFNEIVQ
ECHLTFGLKKGDLLFTGTPEGVGAIADGDQFNLACQGETKGTFFVRMESKE

Sequences:

>Translated_211_residues
MEEIASIYCIGRNYANHAKELGNEVPTEPLLFGKPKSAAVLADGRTLLYPSDKGAIHYEAEIVLKIAKDMEDGDTLDDVV
TEMAIGVDLTLRDLQSKLKQKGHPWLRAKGFRNSAILTPFFPFPGEQESKSLNFSLERNGEVVQLGNTENMLFSFNEIVQ
ECHLTFGLKKGDLLFTGTPEGVGAIADGDQFNLACQGETKGTFFVRMESKE
>Mature_211_residues
MEEIASIYCIGRNYANHAKELGNEVPTEPLLFGKPKSAAVLADGRTLLYPSDKGAIHYEAEIVLKIAKDMEDGDTLDDVV
TEMAIGVDLTLRDLQSKLKQKGHPWLRAKGFRNSAILTPFFPFPGEQESKSLNFSLERNGEVVQLGNTENMLFSFNEIVQ
ECHLTFGLKKGDLLFTGTPEGVGAIADGDQFNLACQGETKGTFFVRMESKE

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=203, Percent_Identity=34.9753694581281, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI215422413, Length=209, Percent_Identity=34.4497607655502, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI66348062, Length=199, Percent_Identity=34.6733668341709, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI156231349, Length=181, Percent_Identity=30.3867403314917, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI40786394, Length=181, Percent_Identity=29.2817679558011, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1787428, Length=205, Percent_Identity=37.5609756097561, Blast_Score=144, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17557057, Length=203, Percent_Identity=30.5418719211823, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324161, Length=222, Percent_Identity=29.7297297297297, Blast_Score=102, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28571789, Length=201, Percent_Identity=29.3532338308458, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28572127, Length=187, Percent_Identity=29.9465240641711, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 23292; Mature: 23292

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEIASIYCIGRNYANHAKELGNEVPTEPLLFGKPKSAAVLADGRTLLYPSDKGAIHYEA
CCCCEEEEEECCCHHHHHHHHHHCCCCCCEEECCCCCCEEEECCEEEEEECCCCCEEEHH
EIVLKIAKDMEDGDTLDDVVTEMAIGVDLTLRDLQSKLKQKGHPWLRAKGFRNSAILTPF
HEEEEEHHCCCCCCCHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCEEECCCCCCEEEEEC
FPFPGEQESKSLNFSLERNGEVVQLGNTENMLFSFNEIVQECHLTFGLKKGDLLFTGTPE
CCCCCCCCCCEEEEEEECCCCEEEECCCCCCEEEHHHHHHHHHHHCCCCCCCEEEECCCC
GVGAIADGDQFNLACQGETKGTFFVRMESKE
CCCEEECCCEEEEEECCCCCCEEEEEEECCC
>Mature Secondary Structure
MEEIASIYCIGRNYANHAKELGNEVPTEPLLFGKPKSAAVLADGRTLLYPSDKGAIHYEA
CCCCEEEEEECCCHHHHHHHHHHCCCCCCEEECCCCCCEEEECCEEEEEECCCCCEEEHH
EIVLKIAKDMEDGDTLDDVVTEMAIGVDLTLRDLQSKLKQKGHPWLRAKGFRNSAILTPF
HEEEEEHHCCCCCCCHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCEEECCCCCCEEEEEC
FPFPGEQESKSLNFSLERNGEVVQLGNTENMLFSFNEIVQECHLTFGLKKGDLLFTGTPE
CCCCCCCCCCEEEEEEECCCCEEEECCCCCCEEEHHHHHHHHHHHCCCCCCCEEEECCCC
GVGAIADGDQFNLACQGETKGTFFVRMESKE
CCCEEECCCEEEEEECCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]