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The map label for this gene is xpt

Identifier: 56963208

GI number: 56963208

Start: 1554892

End: 1555497

Strand: Direct

Name: xpt

Synonym: ABC1443

Alternate gene names: 56963208

Gene position: 1554892-1555497 (Clockwise)

Preceding gene: 56963207

Following gene: 56963209

Centisome position: 36.13

GC content: 44.22

Gene sequence:

>606_bases
ATGGAATTACTAAAAGAAGCGATCCGTAAGCGGGGAAGTGTGTTGTCGAGTGGCGTGCTTAAAGTTGACCAATTTTTAAA
CCACCAAGTCGATACCAACTTGATGAGCGCAATTGGCGAGGAATTTGCCCGCCTATTTGCTGATGAACATGTAACGAAAG
TCGTGACCATCGAGTCGTCTGGTATCGCTCCAAGCTTTATGTGTGCCCATTCTCTTCAAGTGCCATTGATTTTTGCTAGA
AAGAAGAAATCAGTGACGATGGACAAAGAAAACGTTTATTCGAGTCGTGTGTACTCTTTTACTAAAAAGGAATATTCAGA
GGTGACCGTTTCAAAGGATTGGCTTTGCCCCGGTGACCGTGTGTTAATCATTGATGATTTCCTTGCAAACGGACAAGCTG
CTACAGGACTCACGCAAATTGTCGAAGAAGCAGGTGCCACTGTAGCCGGGATCGGCATAGTGATCGAAAAGTCTTTCCAA
GATGGAAGGGCGTTGCTTGAAGGAAAAGGTTATCGGATTGAATCGCTGGCGCGCATTTCTTCACTAGAAGGCAACAAGGT
TCAGTTTGTAGAAGAATCGGCACATTTTGCTTACAACAAATCTTAA

Upstream 100 bases:

>100_bases
CTGACTACGAGTGGTCTTTTTCAGTTGTTATTTTCAAAGCCGAAAGATCACTCTATTTTTATAGTGGTCTTTCGGCTTTT
TATTTTGAAAGGAGAAAGCA

Downstream 100 bases:

>100_bases
AAAGGGCGGAATATACAATTTATGAATGGCCATTATCCTTTATTTAAAAAACAAGACATTGATGCTTTTTTTGCTCTTTT
TCAAAACAATCTCGCAAACT

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MELLKEAIRKRGSVLSSGVLKVDQFLNHQVDTNLMSAIGEEFARLFADEHVTKVVTIESSGIAPSFMCAHSLQVPLIFAR
KKKSVTMDKENVYSSRVYSFTKKEYSEVTVSKDWLCPGDRVLIIDDFLANGQAATGLTQIVEEAGATVAGIGIVIEKSFQ
DGRALLEGKGYRIESLARISSLEGNKVQFVEESAHFAYNKS

Sequences:

>Translated_201_residues
MELLKEAIRKRGSVLSSGVLKVDQFLNHQVDTNLMSAIGEEFARLFADEHVTKVVTIESSGIAPSFMCAHSLQVPLIFAR
KKKSVTMDKENVYSSRVYSFTKKEYSEVTVSKDWLCPGDRVLIIDDFLANGQAATGLTQIVEEAGATVAGIGIVIEKSFQ
DGRALLEGKGYRIESLARISSLEGNKVQFVEESAHFAYNKS
>Mature_201_residues
MELLKEAIRKRGSVLSSGVLKVDQFLNHQVDTNLMSAIGEEFARLFADEHVTKVVTIESSGIAPSFMCAHSLQVPLIFAR
KKKSVTMDKENVYSSRVYSFTKKEYSEVTVSKDWLCPGDRVLIIDDFLANGQAATGLTQIVEEAGATVAGIGIVIEKSFQ
DGRALLEGKGYRIESLARISSLEGNKVQFVEESAHFAYNKS

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT_BACSK (Q5WI27)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_174939.1
- HSSP:   P42085
- ProteinModelPortal:   Q5WI27
- SMR:   Q5WI27
- STRING:   Q5WI27
- EnsemblBacteria:   EBBACT00000046367
- GeneID:   3203591
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1443
- NMPDR:   fig|66692.3.peg.1503
- eggNOG:   COG0503
- GeneTree:   EBGT00050000001498
- HOGENOM:   HBG288993
- OMA:   ATVYSFT
- ProtClustDB:   PRK09219
- BioCyc:   BCLA66692:ABC1443-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 22141; Mature: 22141

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 157-157

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLKEAIRKRGSVLSSGVLKVDQFLNHQVDTNLMSAIGEEFARLFADEHVTKVVTIESS
CHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPSFMCAHSLQVPLIFARKKKSVTMDKENVYSSRVYSFTKKEYSEVTVSKDWLCPGDR
CCCHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCE
VLIIDDFLANGQAATGLTQIVEEAGATVAGIGIVIEKSFQDGRALLEGKGYRIESLARIS
EEEEECCCCCCCCHHHHHHHHHHHCCEEEEEEEEEECCCCCCHHHHCCCCCCHHHHHHHH
SLEGNKVQFVEESAHFAYNKS
HCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MELLKEAIRKRGSVLSSGVLKVDQFLNHQVDTNLMSAIGEEFARLFADEHVTKVVTIESS
CHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPSFMCAHSLQVPLIFARKKKSVTMDKENVYSSRVYSFTKKEYSEVTVSKDWLCPGDR
CCCHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCE
VLIIDDFLANGQAATGLTQIVEEAGATVAGIGIVIEKSFQDGRALLEGKGYRIESLARIS
EEEEECCCCCCCCHHHHHHHHHHHCCEEEEEEEEEECCCCCCHHHHCCCCCCHHHHHHHH
SLEGNKVQFVEESAHFAYNKS
HCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA