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The map label for this gene is yfiK [H]

Identifier: 56963198

GI number: 56963198

Start: 1546036

End: 1546668

Strand: Direct

Name: yfiK [H]

Synonym: ABC1433

Alternate gene names: 56963198

Gene position: 1546036-1546668 (Clockwise)

Preceding gene: 56963197

Following gene: 56963199

Centisome position: 35.92

GC content: 43.92

Gene sequence:

>633_bases
ATGATTAAGGTGCTGCTCGCAGAAGACCAAGTCATGGTACGGCAAGGGTTAAAAGCAATGATCGAAACCGATGAAGACAT
CAAAGTAACTGGAGAGGCTGATGATGGGAGAAAAGCGCTGCGTTTATGTGAAACGCATGTGTTCGATGTGGCGATTTTAG
ATATTCGCATGCCTGAAATGGATGGAATTGAAGCGGCCAAGATGATGCGCTTGCGTTATCCGAAAATGAAAATTTTGATG
CTGACCACGTTTGATGATCATCAGTACGTGGTCGAGTCCTTAAAATTAGGCGTTAATGGTTATATGCTGAAAAACGGCGA
CACGGAATCATTGATTCGTTCGATTAAAAGTACTATAAATGGAGGTCTTTCCCTTGAGGATCAAGTAGCTGCTAAAGTAG
TGCCTACTCTTCTGCAAAATCAAGAGGAGCCGTCTATTGATCCTAGCCTAACCCCAAGGGAAAGGGCGATTTTAACATGT
ATAGGGGAAGGGCTAAACAACAAAGAGATAGCAGAGCGATTAGGCTTGTCAGTTGGCACAGTAAAAAATCAAACGAGCCA
CATTTTTGACAAGTTGGCATTAAGGGATCGGACCCAACTGGCCATTTATGCGATTCGCCATCGGCTTGTGTGA

Upstream 100 bases:

>100_bases
GACCGATTAGAAAAAGTGGATGGTTCCATGGACGTTATTCATGATGGCTCACAATTTGTTGTCAGGGGGAGTATACGATT
AGCTGATCGGAGAGGATAGA

Downstream 100 bases:

>100_bases
GCGGAGAAAAAGTGACGAAAGTAACAACAGTCATTTGAACGAGTGACCGGAGTCAGTAGGGACTTCGGTTTTTTTGTTTT
AAGCTACATGTAAGAAAGTA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MIKVLLAEDQVMVRQGLKAMIETDEDIKVTGEADDGRKALRLCETHVFDVAILDIRMPEMDGIEAAKMMRLRYPKMKILM
LTTFDDHQYVVESLKLGVNGYMLKNGDTESLIRSIKSTINGGLSLEDQVAAKVVPTLLQNQEEPSIDPSLTPRERAILTC
IGEGLNNKEIAERLGLSVGTVKNQTSHIFDKLALRDRTQLAIYAIRHRLV

Sequences:

>Translated_210_residues
MIKVLLAEDQVMVRQGLKAMIETDEDIKVTGEADDGRKALRLCETHVFDVAILDIRMPEMDGIEAAKMMRLRYPKMKILM
LTTFDDHQYVVESLKLGVNGYMLKNGDTESLIRSIKSTINGGLSLEDQVAAKVVPTLLQNQEEPSIDPSLTPRERAILTC
IGEGLNNKEIAERLGLSVGTVKNQTSHIFDKLALRDRTQLAIYAIRHRLV
>Mature_210_residues
MIKVLLAEDQVMVRQGLKAMIETDEDIKVTGEADDGRKALRLCETHVFDVAILDIRMPEMDGIEAAKMMRLRYPKMKILM
LTTFDDHQYVVESLKLGVNGYMLKNGDTESLIRSIKSTINGGLSLEDQVAAKVVPTLLQNQEEPSIDPSLTPRERAILTC
IGEGLNNKEIAERLGLSVGTVKNQTSHIFDKLALRDRTQLAIYAIRHRLV

Specific function: Member of the two-component regulatory system yfiJ/yfiK [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=31.5789473684211, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787473, Length=207, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=31.1881188118812, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1788521, Length=209, Percent_Identity=30.1435406698565, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1786747, Length=207, Percent_Identity=24.6376811594203, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788712, Length=184, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788546, Length=206, Percent_Identity=25.7281553398058, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082052, Length=142, Percent_Identity=28.8732394366197, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788550, Length=79, Percent_Identity=39.2405063291139, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1790437, Length=147, Percent_Identity=27.2108843537415, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23547; Mature: 23547

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVLLAEDQVMVRQGLKAMIETDEDIKVTGEADDGRKALRLCETHVFDVAILDIRMPEM
CEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHEEEEEEEECCCC
DGIEAAKMMRLRYPKMKILMLTTFDDHQYVVESLKLGVNGYMLKNGDTESLIRSIKSTIN
CCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHC
GGLSLEDQVAAKVVPTLLQNQEEPSIDPSLTPRERAILTCIGEGLNNKEIAERLGLSVGT
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCC
VKNQTSHIFDKLALRDRTQLAIYAIRHRLV
CCCHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIKVLLAEDQVMVRQGLKAMIETDEDIKVTGEADDGRKALRLCETHVFDVAILDIRMPEM
CEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHEEEEEEEECCCC
DGIEAAKMMRLRYPKMKILMLTTFDDHQYVVESLKLGVNGYMLKNGDTESLIRSIKSTIN
CCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHC
GGLSLEDQVAAKVVPTLLQNQEEPSIDPSLTPRERAILTCIGEGLNNKEIAERLGLSVGT
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCC
VKNQTSHIFDKLALRDRTQLAIYAIRHRLV
CCCHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8973323; 9384377 [H]