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The map label for this gene is kat [H]

Identifier: 56963055

GI number: 56963055

Start: 1403976

End: 1405442

Strand: Direct

Name: kat [H]

Synonym: ABC1283

Alternate gene names: 56963055

Gene position: 1403976-1405442 (Clockwise)

Preceding gene: 56963054

Following gene: 56963056

Centisome position: 32.62

GC content: 44.24

Gene sequence:

>1467_bases
ATGCGACGATTAACAGATAATCAAGGACATCCAATTTACGACAATCAAAACTCGCGTACAGCTGGCCAACATGGTCCAAC
TTTGTTAGAAGACTACCATTTGGTGGAAAAACTCGCCCATTTTGACCGTGAACGGATTCCCGAACGGGTTGTCCATGCGC
GGGGGGCTGGTGCCCATGGCGTATTTAAAGTAAAAAACAATATGAAGCGTTATACAAAAGCAAACTTTCTTTCTGAAGAT
GGGAAAGAAACGCCTGTTTTCGTCCGCTTCTCAACAGTCATACACGGTGGTACCTCTCCAGAGACGCTTCGCGATCCACG
GGGATTTTCTGTTAAGTTTTATACAGAAGAAGGAAACTATGATTTTGTCGGCAACAACTTGCCTGTTTTCTTCATTCGTG
ACGCGATTAAATTTCCGGATGTGATCCATTCTTTAAAGCCAGATCCACGTACGAATATCCAAAGCCCTGACCGGTATTGG
GATTTTATGAGCTTAACGCCAGAATCAACAAACATGCTTACCCATCTATTTACGGACGAAGGCATTCCTGCTTCTTACCG
GGAAATGCGGGGTTCAAGCGTCCATGCGTTCAAGTGGGTCAATGAACACGGAAATATGGTTTATGTCAAGCTGAACTGGG
TTCCGAAAATGGGCATCCGTAACTTGTCAATGGAAGAAGCCGCCAATATACAAGCTCATGACTTTAACCATGCAACGAGA
GACTTATACGAAGCGATTGAACGTGGCGATTATCCAGAGTGGGATTTATATGTACAAATCCTTGATCCAGCCGATCTAGA
CAATTTCGATTTTCATCCGCTTGATGCAACGAAAGATTGGCTTGAGGAAGACATTCCTTCTCAATTAGTAGGGACGATGA
CGCTGAACCGCAACCCTGAGAATGTCTTTGCCGAAACGGAACAAGTTGGCTTTAACCCTGGAAATCTTGTCCCTGGCTTT
GAGCCATCGGAAGACAAAATGCTTCAAGGGCGCATCTTCTCGTATTCGGATACACAACGATACCGTGTCGGTGCAAACTA
CTTGGATCTCCCAATTAACTGCCCATTTGCGCAAAAGGCAAACAATACTAGAGATGGGGCAATGCCAATCGGCCAACAAA
CAAACCGGATCAATTATGAACCGAACCGTTATCAAGATACGCCAAAAGAAGCGGAAGGCTATGAAGACTACCGTGCGCCT
ATTAATGGCACTATAGGACGAATTGCGATTGAAAAGAAAAACAACTTTGGCCAAGCAGGCAAAATTTATCGAAACTATCC
AAAAAATGTCCAAGATGCGCTTATTAAAAACATTGCAAATGATTTAAAACAAGTTGCTCCAGAAACAGCGCTCCGAGCCA
TTTGCAACTTTTACCGTGCTGATGAAGACTACGGACAACGCCTTGCGGATGCCATTGGAATGGACATCTCTGAATATGTG
AAACATGGATCAGAGAACAACTCCTAA

Upstream 100 bases:

>100_bases
TAACGATAATGATTCCAATTAAGGAATAAGTTTAGTTGTATCGTTCATTTGCCAACGATGACATATTGGTAAAGCTTAAT
GATCAAAAGGGGGATTACAT

Downstream 100 bases:

>100_bases
CTCGAACAACCAGCGTGACTGTTTAGTCCGCTGGTTTTTTTATAATTATTCGCATAGCCATCCCTTTCGTCTCATAAAGT
AGCAATAACGAAAGGAGTTG

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MRRLTDNQGHPIYDNQNSRTAGQHGPTLLEDYHLVEKLAHFDRERIPERVVHARGAGAHGVFKVKNNMKRYTKANFLSED
GKETPVFVRFSTVIHGGTSPETLRDPRGFSVKFYTEEGNYDFVGNNLPVFFIRDAIKFPDVIHSLKPDPRTNIQSPDRYW
DFMSLTPESTNMLTHLFTDEGIPASYREMRGSSVHAFKWVNEHGNMVYVKLNWVPKMGIRNLSMEEAANIQAHDFNHATR
DLYEAIERGDYPEWDLYVQILDPADLDNFDFHPLDATKDWLEEDIPSQLVGTMTLNRNPENVFAETEQVGFNPGNLVPGF
EPSEDKMLQGRIFSYSDTQRYRVGANYLDLPINCPFAQKANNTRDGAMPIGQQTNRINYEPNRYQDTPKEAEGYEDYRAP
INGTIGRIAIEKKNNFGQAGKIYRNYPKNVQDALIKNIANDLKQVAPETALRAICNFYRADEDYGQRLADAIGMDISEYV
KHGSENNS

Sequences:

>Translated_488_residues
MRRLTDNQGHPIYDNQNSRTAGQHGPTLLEDYHLVEKLAHFDRERIPERVVHARGAGAHGVFKVKNNMKRYTKANFLSED
GKETPVFVRFSTVIHGGTSPETLRDPRGFSVKFYTEEGNYDFVGNNLPVFFIRDAIKFPDVIHSLKPDPRTNIQSPDRYW
DFMSLTPESTNMLTHLFTDEGIPASYREMRGSSVHAFKWVNEHGNMVYVKLNWVPKMGIRNLSMEEAANIQAHDFNHATR
DLYEAIERGDYPEWDLYVQILDPADLDNFDFHPLDATKDWLEEDIPSQLVGTMTLNRNPENVFAETEQVGFNPGNLVPGF
EPSEDKMLQGRIFSYSDTQRYRVGANYLDLPINCPFAQKANNTRDGAMPIGQQTNRINYEPNRYQDTPKEAEGYEDYRAP
INGTIGRIAIEKKNNFGQAGKIYRNYPKNVQDALIKNIANDLKQVAPETALRAICNFYRADEDYGQRLADAIGMDISEYV
KHGSENNS
>Mature_488_residues
MRRLTDNQGHPIYDNQNSRTAGQHGPTLLEDYHLVEKLAHFDRERIPERVVHARGAGAHGVFKVKNNMKRYTKANFLSED
GKETPVFVRFSTVIHGGTSPETLRDPRGFSVKFYTEEGNYDFVGNNLPVFFIRDAIKFPDVIHSLKPDPRTNIQSPDRYW
DFMSLTPESTNMLTHLFTDEGIPASYREMRGSSVHAFKWVNEHGNMVYVKLNWVPKMGIRNLSMEEAANIQAHDFNHATR
DLYEAIERGDYPEWDLYVQILDPADLDNFDFHPLDATKDWLEEDIPSQLVGTMTLNRNPENVFAETEQVGFNPGNLVPGF
EPSEDKMLQGRIFSYSDTQRYRVGANYLDLPINCPFAQKANNTRDGAMPIGQQTNRINYEPNRYQDTPKEAEGYEDYRAP
INGTIGRIAIEKKNNFGQAGKIYRNYPKNVQDALIKNIANDLKQVAPETALRAICNFYRADEDYGQRLADAIGMDISEYV
KHGSENNS

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=468, Percent_Identity=45.5128205128205, Blast_Score=416, Evalue=1e-116,
Organism=Escherichia coli, GI48994891, Length=496, Percent_Identity=43.5483870967742, Blast_Score=390, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71998444, Length=471, Percent_Identity=43.0997876857749, Blast_Score=412, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI25147792, Length=467, Percent_Identity=43.6830835117773, Blast_Score=407, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI25151141, Length=467, Percent_Identity=43.6830835117773, Blast_Score=407, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6320462, Length=503, Percent_Identity=39.7614314115308, Blast_Score=341, Evalue=1e-94,
Organism=Saccharomyces cerevisiae, GI6321525, Length=537, Percent_Identity=35.0093109869646, Blast_Score=303, Evalue=4e-83,
Organism=Drosophila melanogaster, GI17981717, Length=478, Percent_Identity=42.6778242677824, Blast_Score=401, Evalue=1e-112,
Organism=Drosophila melanogaster, GI19920968, Length=478, Percent_Identity=37.4476987447699, Blast_Score=373, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55861; Mature: 55861

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLTDNQGHPIYDNQNSRTAGQHGPTLLEDYHLVEKLAHFDRERIPERVVHARGAGAHG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VFKVKNNMKRYTKANFLSEDGKETPVFVRFSTVIHGGTSPETLRDPRGFSVKFYTEEGNY
EEEEHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHCCCCCCEEEEEEECCCE
DFVGNNLPVFFIRDAIKFPDVIHSLKPDPRTNIQSPDRYWDFMSLTPESTNMLTHLFTDE
EEECCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHEECCCCCHHHEEEEECCC
GIPASYREMRGSSVHAFKWVNEHGNMVYVKLNWVPKMGIRNLSMEEAANIQAHDFNHATR
CCCHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCCCCCHHHH
DLYEAIERGDYPEWDLYVQILDPADLDNFDFHPLDATKDWLEEDIPSQLVGTMTLNRNPE
HHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHCCHHHHHEEEEECCCCH
NVFAETEQVGFNPGNLVPGFEPSEDKMLQGRIFSYSDTQRYRVGANYLDLPINCPFAQKA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEECCCEEECCCCCCCHHCC
NNTRDGAMPIGQQTNRINYEPNRYQDTPKEAEGYEDYRAPINGTIGRIAIEKKNNFGQAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHCCCCCCCEEEEEEECCCCCCCCC
KIYRNYPKNVQDALIKNIANDLKQVAPETALRAICNFYRADEDYGQRLADAIGMDISEYV
HHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHH
KHGSENNS
HCCCCCCC
>Mature Secondary Structure
MRRLTDNQGHPIYDNQNSRTAGQHGPTLLEDYHLVEKLAHFDRERIPERVVHARGAGAHG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VFKVKNNMKRYTKANFLSEDGKETPVFVRFSTVIHGGTSPETLRDPRGFSVKFYTEEGNY
EEEEHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHCCCCCCEEEEEEECCCE
DFVGNNLPVFFIRDAIKFPDVIHSLKPDPRTNIQSPDRYWDFMSLTPESTNMLTHLFTDE
EEECCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHEECCCCCHHHEEEEECCC
GIPASYREMRGSSVHAFKWVNEHGNMVYVKLNWVPKMGIRNLSMEEAANIQAHDFNHATR
CCCHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCCCCCHHHH
DLYEAIERGDYPEWDLYVQILDPADLDNFDFHPLDATKDWLEEDIPSQLVGTMTLNRNPE
HHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHCCHHHHHEEEEECCCCH
NVFAETEQVGFNPGNLVPGFEPSEDKMLQGRIFSYSDTQRYRVGANYLDLPINCPFAQKA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEECCCEEECCCCCCCHHCC
NNTRDGAMPIGQQTNRINYEPNRYQDTPKEAEGYEDYRAPINGTIGRIAIEKKNNFGQAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHCCCCCCCEEEEEEECCCCCCCCC
KIYRNYPKNVQDALIKNIANDLKQVAPETALRAICNFYRADEDYGQRLADAIGMDISEYV
HHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHH
KHGSENNS
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]