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The map label for this gene is gatA [H]

Identifier: 55981766

GI number: 55981766

Start: 1678246

End: 1679550

Strand: Direct

Name: gatA [H]

Synonym: TTHA1797

Alternate gene names: 55981766

Gene position: 1678246-1679550 (Clockwise)

Preceding gene: 55981765

Following gene: 55981769

Centisome position: 90.73

GC content: 71.57

Gene sequence:

>1305_bases
ATGGACCTGCTTGAGGCGAAGCGCCTTCTGGAAACGGGAAGGACCACCCCTCTAGCCCTTTTGGAAGAGGCCCTGGAGCG
GGCCAAGGCCTTCCAGGACCGGAACGCCCTCGCCTACCTGGACGAGGAGGCCGCCCGCAAGGAGGCCCTGGCCCTCACGG
AGGAGCTCAGGCGGGGCCAGGTGCGGGGGCCTCTCCACGGCCTTCCCCTCACCGTAAAGGACCTCTTCCCCGTGAAGGGG
ATGCCCACCCGGGCGGGGACGAAGGCCCCCCTCCCTCCCCTTCCCGAGGAGGCGAGGGCGGTGCGCCGCCTGAGGGAGGC
CGGGGCCCTCCTCTTCGCCAAGACCAACATGCACGAGATCGCCCTGGGCATCACCGGGGAGAACCCCTGGACGGGCCCGG
TGCGGAACGCCGTGGACCCCAGCCGCCAGGCCGGGGGGTCTAGCGGCGGGAGCGCCGTGGCCGTGGCCTTAGGGATCGGC
CTCGCCTCCCTGGGCACGGACACCGGGGGGTCCATCCGCATCCCCGCGGGCTTCAACGGGGTGGTGGGCTTCAAGCCCTC
CTACGGCCGGGTGAGCCTGGAAGGGGCCCTTCCCCTCTCCCGCTCCACGGACCACGCCGGGCCCCTCACCCGGAGTGTGC
GGGACGCCCACTTCCTCACGGAGATCCTGGCCGGGGAGAGCATTCCCTTGGAGGGCGTCCAGAACCCCGTCTTCGGGGTC
CCCCTGGACTTCCTGGAGGGGAGGCTTGGGGTGGAGGTGCGGAAGGCCTTCACCCGGCTCTTGGAAGATCTCCCCGCCCT
AAGGGCCGAGGTGAGGGAGGTCTCCCTTCCCCTGGAAGGCGTCTACGAGGTCTACACCCGCCTGGTGCGCTACGAGGCGG
CCCGGATCCACGAGAAGGCCCTGAAGGAGCATCCCGAAGGCTTCTCCCCCCAGGTGCGGGAAGCCCTCCTCGCGGGCCTC
GCCCTCACGGAGAAGGACTACCGGGACGCCGTGGCCGAGCGGGAGGCGCTCAGGCTGGAGCTGGTGAAGGCCCTGAGGGG
GGTGGACGCCCTCCTCCTCCCCGTCCAGCCCCTCCCCGCCCCTCCCTTGGGCACGGAGGAGGTGGAGCTGGAGTCCGGCA
GGAAGGGCCACCGCGAGGCCTTCATCACCCTCACCCTGCCCTTCAGCCTCCTCGGGGTCCCCACCCTCGCCCTCCCCTTC
GCCAAGGTGGAGGGGATGCCGGTGGGGCTCCAGGTGGTGGGGGCGTACGGGGAGGACGGGAAGGTCCTGGCCCTCGGGGG
CTGGCTCGAGGCCCGGCTAGGCTAG

Upstream 100 bases:

>100_bases
GAGCTTTTGGCCCTGGCCCTAAAGGAGCGGGAAGTCCTCACCTACACCTGGCCCGGAAAGCCCCTACCCGAGGAGCCGGA
AGGCGCTTTTATAATGGAGC

Downstream 100 bases:

>100_bases
CCCCAGGTAGAGGAGGGCCAGGGAGAAGAGGGTGAGGGGAAGCCCGAAGCGGAGGTGCTCCAGGAGGCCCACCCGCACCC
CCTCCCGTCCCGCCCCCTCG

Product: amidase

Products: NA

Alternate protein names: Glu-ADT subunit A [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MDLLEAKRLLETGRTTPLALLEEALERAKAFQDRNALAYLDEEAARKEALALTEELRRGQVRGPLHGLPLTVKDLFPVKG
MPTRAGTKAPLPPLPEEARAVRRLREAGALLFAKTNMHEIALGITGENPWTGPVRNAVDPSRQAGGSSGGSAVAVALGIG
LASLGTDTGGSIRIPAGFNGVVGFKPSYGRVSLEGALPLSRSTDHAGPLTRSVRDAHFLTEILAGESIPLEGVQNPVFGV
PLDFLEGRLGVEVRKAFTRLLEDLPALRAEVREVSLPLEGVYEVYTRLVRYEAARIHEKALKEHPEGFSPQVREALLAGL
ALTEKDYRDAVAEREALRLELVKALRGVDALLLPVQPLPAPPLGTEEVELESGRKGHREAFITLTLPFSLLGVPTLALPF
AKVEGMPVGLQVVGAYGEDGKVLALGGWLEARLG

Sequences:

>Translated_434_residues
MDLLEAKRLLETGRTTPLALLEEALERAKAFQDRNALAYLDEEAARKEALALTEELRRGQVRGPLHGLPLTVKDLFPVKG
MPTRAGTKAPLPPLPEEARAVRRLREAGALLFAKTNMHEIALGITGENPWTGPVRNAVDPSRQAGGSSGGSAVAVALGIG
LASLGTDTGGSIRIPAGFNGVVGFKPSYGRVSLEGALPLSRSTDHAGPLTRSVRDAHFLTEILAGESIPLEGVQNPVFGV
PLDFLEGRLGVEVRKAFTRLLEDLPALRAEVREVSLPLEGVYEVYTRLVRYEAARIHEKALKEHPEGFSPQVREALLAGL
ALTEKDYRDAVAEREALRLELVKALRGVDALLLPVQPLPAPPLGTEEVELESGRKGHREAFITLTLPFSLLGVPTLALPF
AKVEGMPVGLQVVGAYGEDGKVLALGGWLEARLG
>Mature_434_residues
MDLLEAKRLLETGRTTPLALLEEALERAKAFQDRNALAYLDEEAARKEALALTEELRRGQVRGPLHGLPLTVKDLFPVKG
MPTRAGTKAPLPPLPEEARAVRRLREAGALLFAKTNMHEIALGITGENPWTGPVRNAVDPSRQAGGSSGGSAVAVALGIG
LASLGTDTGGSIRIPAGFNGVVGFKPSYGRVSLEGALPLSRSTDHAGPLTRSVRDAHFLTEILAGESIPLEGVQNPVFGV
PLDFLEGRLGVEVRKAFTRLLEDLPALRAEVREVSLPLEGVYEVYTRLVRYEAARIHEKALKEHPEGFSPQVREALLAGL
ALTEKDYRDAVAEREALRLELVKALRGVDALLLPVQPLPAPPLGTEEVELESGRKGHREAFITLTLPFSLLGVPTLALPF
AKVEGMPVGLQVVGAYGEDGKVLALGGWLEARLG

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=498, Percent_Identity=31.1244979919679, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI195972892, Length=485, Percent_Identity=27.4226804123711, Blast_Score=123, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17543272, Length=459, Percent_Identity=26.5795206971678, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17537465, Length=500, Percent_Identity=26, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17538252, Length=421, Percent_Identity=26.3657957244656, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17556264, Length=473, Percent_Identity=26.215644820296, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538254, Length=419, Percent_Identity=25.7756563245823, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71990152, Length=195, Percent_Identity=33.8461538461538, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17556278, Length=237, Percent_Identity=31.6455696202532, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17556276, Length=237, Percent_Identity=31.6455696202532, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323950, Length=467, Percent_Identity=28.051391862955, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6319685, Length=382, Percent_Identity=28.0104712041885, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320448, Length=238, Percent_Identity=32.7731092436975, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648113, Length=479, Percent_Identity=29.6450939457203, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24652985, Length=448, Percent_Identity=28.7946428571429, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19922090, Length=448, Percent_Identity=28.7946428571429, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24652981, Length=448, Percent_Identity=28.7946428571429, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24652983, Length=448, Percent_Identity=28.7946428571429, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI45550774, Length=452, Percent_Identity=26.1061946902655, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24648435, Length=452, Percent_Identity=25.8849557522124, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24648437, Length=452, Percent_Identity=25.8849557522124, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24648441, Length=409, Percent_Identity=25.9168704156479, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24648439, Length=409, Percent_Identity=25.9168704156479, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI161078093, Length=497, Percent_Identity=27.7665995975855, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24644968, Length=450, Percent_Identity=28.2222222222222, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21356731, Length=468, Percent_Identity=27.5641025641026, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: NA

Molecular weight: Translated: 46521; Mature: 46521

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLEAKRLLETGRTTPLALLEEALERAKAFQDRNALAYLDEEAARKEALALTEELRRGQ
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHCCC
VRGPLHGLPLTVKDLFPVKGMPTRAGTKAPLPPLPEEARAVRRLREAGALLFAKTNMHEI
CCCCCCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCEEE
ALGITGENPWTGPVRNAVDPSRQAGGSSGGSAVAVALGIGLASLGTDTGGSIRIPAGFNG
EEEECCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCC
VVGFKPSYGRVSLEGALPLSRSTDHAGPLTRSVRDAHFLTEILAGESIPLEGVQNPVFGV
CCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PLDFLEGRLGVEVRKAFTRLLEDLPALRAEVREVSLPLEGVYEVYTRLVRYEAARIHEKA
CHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LKEHPEGFSPQVREALLAGLALTEKDYRDAVAEREALRLELVKALRGVDALLLPVQPLPA
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
PPLGTEEVELESGRKGHREAFITLTLPFSLLGVPTLALPFAKVEGMPVGLQVVGAYGEDG
CCCCCCCEECCCCCCCCCEEEEEEEECHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCC
KVLALGGWLEARLG
CEEEECCCHHCCCC
>Mature Secondary Structure
MDLLEAKRLLETGRTTPLALLEEALERAKAFQDRNALAYLDEEAARKEALALTEELRRGQ
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHCCC
VRGPLHGLPLTVKDLFPVKGMPTRAGTKAPLPPLPEEARAVRRLREAGALLFAKTNMHEI
CCCCCCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCEEE
ALGITGENPWTGPVRNAVDPSRQAGGSSGGSAVAVALGIGLASLGTDTGGSIRIPAGFNG
EEEECCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCC
VVGFKPSYGRVSLEGALPLSRSTDHAGPLTRSVRDAHFLTEILAGESIPLEGVQNPVFGV
CCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PLDFLEGRLGVEVRKAFTRLLEDLPALRAEVREVSLPLEGVYEVYTRLVRYEAARIHEKA
CHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LKEHPEGFSPQVREALLAGLALTEKDYRDAVAEREALRLELVKALRGVDALLLPVQPLPA
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
PPLGTEEVELESGRKGHREAFITLTLPFSLLGVPTLALPFAKVEGMPVGLQVVGAYGEDG
CCCCCCCEECCCCCCCCCEEEEEEEECHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCC
KVLALGGWLEARLG
CEEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA