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The map label for this gene is resE [H]

Identifier: 55981692

GI number: 55981692

Start: 1618192

End: 1619313

Strand: Direct

Name: resE [H]

Synonym: TTHA1723

Alternate gene names: 55981692

Gene position: 1618192-1619313 (Clockwise)

Preceding gene: 55981691

Following gene: 55981693

Centisome position: 87.48

GC content: 69.16

Gene sequence:

>1122_bases
ATGCGCCTCTTCCTTAAACTCTTCCTGAGCCACCTCCTGGTGGCCCTCCTCGCCCTTTTGCTCCTCCTGCTGCTGGCGGA
GGCCTTCGCCCCCGCCTTCTACCGGGGGCACGTGGAGCGCATGCTCCACGCCCTCTCCATGATGGGGGGCGGCATGATGG
GCGAGGCCCTGAGGCGGGACCTGGAGGAGGGGCTTCGCTCCACCCTCACCGCCGCCCTTCTCGCCGCTTTACCCCTCGCC
GCCCTGGGCGCCCTCCTCACCGCCTCCTTCGCCAGCCTGCGCCTCGCCAGGACCGCAAGGCTCCTCGCCGAGGGGAGCCG
CCGGATGGCCGAGGGGGAGTACGGGGTCCGCCTTCCCCTTTTGGAGCGGGACGAGCTCGGGGAGCTCGCCCTCCACTTCA
ACCGCCTGGCCGAGGCCCTGGAGAAGGTGGAGAAGACCCGGGCCGAGCTCATCGGCACCGTGGCCCACGAGCTCAGAACC
CCCCTGGCCGCCCTCCAAGGGTACGCGGAGGGGCTTATAGACGGGGTCCTTTCCAAGGAGAAGGCCGCGGAGGGGATTCT
GCGGGAGGTGAAGGCCATGCGCCGCCTGGTGGAGGACCTTTCCTTGGTCTCCCGGGTGGAGGCGAAGGCGGTGGAGATCC
GTCCCAGGCCCCTGGACCCCAAGGGCCTCCTCGAGGAGGCCCTGGCCCGCTTCCAAAGCGCCTTCCAGGCCAAGGGGGTG
GCGCTTTCCCTGGAGGCCCAAGACCCCCTTCCCCAGGTGTGGGCCGACGAGGAAAGGGTCCTCCAGGTGCTGGCCAACCT
CCTCACCAACGCCCTCCGCCACACCCCGCAAGGCGGCGAGGTGCGCCTTAGGGCCTTCCGCCAGGGGGAGGCCGTGGCCT
TCCAAGTGGCGGACACCGGCCCCGGCATCCCCGAGGAGCACCTGCCCCACATCTTTGAGCGCTTCTACCGGGTGGACAAG
GCACGTAGCCGCAAGGAGGGAGGAAGCGGGGTGGGGCTCACCGTCGCCAAGGGCCTGGTGGAGGCCATGGGGGGGAGGAT
CTTTGTGGAAAGCCGGGTGGGCGAGGGAACAACCTTCACCTTCACCCTCCCCCTTTACACGGGCTTAACGCTCAAGGGTT
AG

Upstream 100 bases:

>100_bases
GTCCACATCGCCGCCCTTCGGAAGAAGCTCGGGGACGATCCGGAAAACCCCCGCTTCATTGAAACGGTGCGGGGCGTGGG
TTACCGCTTCAAGGACCCGG

Downstream 100 bases:

>100_bases
GGTTTGGGGCATGAGAAGGATCCTGGCGTTCCTAGGCGTGGCGTTGGCCCTGGGGCTGGCCCAAACCCCCTCTCCAGAGG
CCCTAAGGGGCGCCTCTCCC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MRLFLKLFLSHLLVALLALLLLLLLAEAFAPAFYRGHVERMLHALSMMGGGMMGEALRRDLEEGLRSTLTAALLAALPLA
ALGALLTASFASLRLARTARLLAEGSRRMAEGEYGVRLPLLERDELGELALHFNRLAEALEKVEKTRAELIGTVAHELRT
PLAALQGYAEGLIDGVLSKEKAAEGILREVKAMRRLVEDLSLVSRVEAKAVEIRPRPLDPKGLLEEALARFQSAFQAKGV
ALSLEAQDPLPQVWADEERVLQVLANLLTNALRHTPQGGEVRLRAFRQGEAVAFQVADTGPGIPEEHLPHIFERFYRVDK
ARSRKEGGSGVGLTVAKGLVEAMGGRIFVESRVGEGTTFTFTLPLYTGLTLKG

Sequences:

>Translated_373_residues
MRLFLKLFLSHLLVALLALLLLLLLAEAFAPAFYRGHVERMLHALSMMGGGMMGEALRRDLEEGLRSTLTAALLAALPLA
ALGALLTASFASLRLARTARLLAEGSRRMAEGEYGVRLPLLERDELGELALHFNRLAEALEKVEKTRAELIGTVAHELRT
PLAALQGYAEGLIDGVLSKEKAAEGILREVKAMRRLVEDLSLVSRVEAKAVEIRPRPLDPKGLLEEALARFQSAFQAKGV
ALSLEAQDPLPQVWADEERVLQVLANLLTNALRHTPQGGEVRLRAFRQGEAVAFQVADTGPGIPEEHLPHIFERFYRVDK
ARSRKEGGSGVGLTVAKGLVEAMGGRIFVESRVGEGTTFTFTLPLYTGLTLKG
>Mature_373_residues
MRLFLKLFLSHLLVALLALLLLLLLAEAFAPAFYRGHVERMLHALSMMGGGMMGEALRRDLEEGLRSTLTAALLAALPLA
ALGALLTASFASLRLARTARLLAEGSRRMAEGEYGVRLPLLERDELGELALHFNRLAEALEKVEKTRAELIGTVAHELRT
PLAALQGYAEGLIDGVLSKEKAAEGILREVKAMRRLVEDLSLVSRVEAKAVEIRPRPLDPKGLLEEALARFQSAFQAKGV
ALSLEAQDPLPQVWADEERVLQVLANLLTNALRHTPQGGEVRLRAFRQGEAVAFQVADTGPGIPEEHLPHIFERFYRVDK
ARSRKEGGSGVGLTVAKGLVEAMGGRIFVESRVGEGTTFTFTLPLYTGLTLKG

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=266, Percent_Identity=37.218045112782, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=36.480686695279, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI48994928, Length=236, Percent_Identity=36.0169491525424, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI145693157, Length=239, Percent_Identity=30.1255230125523, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786783, Length=269, Percent_Identity=31.2267657992565, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787894, Length=268, Percent_Identity=29.8507462686567, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI87081816, Length=246, Percent_Identity=31.7073170731707, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788713, Length=246, Percent_Identity=31.3008130081301, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=28.9915966386555, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=31.3559322033898, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=30.379746835443, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=28.9915966386555, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788549, Length=227, Percent_Identity=29.5154185022026, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87082128, Length=237, Percent_Identity=29.957805907173, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788279, Length=244, Percent_Identity=26.2295081967213, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787374, Length=293, Percent_Identity=30.3754266211604, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790861, Length=248, Percent_Identity=32.258064516129, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790300, Length=242, Percent_Identity=30.9917355371901, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789808, Length=219, Percent_Identity=26.4840182648402, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=74, Percent_Identity=43.2432432432432, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40675; Mature: 40675

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFLKLFLSHLLVALLALLLLLLLAEAFAPAFYRGHVERMLHALSMMGGGMMGEALRRD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LEEGLRSTLTAALLAALPLAALGALLTASFASLRLARTARLLAEGSRRMAEGEYGVRLPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LERDELGELALHFNRLAEALEKVEKTRAELIGTVAHELRTPLAALQGYAEGLIDGVLSKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAAEGILREVKAMRRLVEDLSLVSRVEAKAVEIRPRPLDPKGLLEEALARFQSAFQAKGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
ALSLEAQDPLPQVWADEERVLQVLANLLTNALRHTPQGGEVRLRAFRQGEAVAFQVADTG
EEEEECCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHEECCCCEEEEEEECCC
PGIPEEHLPHIFERFYRVDKARSRKEGGSGVGLTVAKGLVEAMGGRIFVESRVGEGTTFT
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCEEE
FTLPLYTGLTLKG
EEEHHHCCCCCCC
>Mature Secondary Structure
MRLFLKLFLSHLLVALLALLLLLLLAEAFAPAFYRGHVERMLHALSMMGGGMMGEALRRD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LEEGLRSTLTAALLAALPLAALGALLTASFASLRLARTARLLAEGSRRMAEGEYGVRLPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LERDELGELALHFNRLAEALEKVEKTRAELIGTVAHELRTPLAALQGYAEGLIDGVLSKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAAEGILREVKAMRRLVEDLSLVSRVEAKAVEIRPRPLDPKGLLEEALARFQSAFQAKGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
ALSLEAQDPLPQVWADEERVLQVLANLLTNALRHTPQGGEVRLRAFRQGEAVAFQVADTG
EEEEECCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHEECCCCEEEEEEECCC
PGIPEEHLPHIFERFYRVDKARSRKEGGSGVGLTVAKGLVEAMGGRIFVESRVGEGTTFT
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCEEE
FTLPLYTGLTLKG
EEEHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]