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The map label for this gene is trmB [H]

Identifier: 55981588

GI number: 55981588

Start: 1534617

End: 1535552

Strand: Direct

Name: trmB [H]

Synonym: TTHA1619

Alternate gene names: 55981588

Gene position: 1534617-1535552 (Clockwise)

Preceding gene: 55981585

Following gene: 55981589

Centisome position: 82.96

GC content: 71.58

Gene sequence:

>936_bases
GTGCTGGTCGTGCCCGCCCGCCTCCACCGCTGGCCTCCCGAAGTGCAGGACCTCTTCGGCCGGGAAGGCCCCCTGGTCCT
GGAGATCGGCTTCGGCGACGGCCGCTTCACGGCGGAGCTCGCCCGGTCGCGCCCCGACTGGCTCGTCCTCGGGGCCGAGG
TCTCGGCGGCCAGCGTCCTCCGGGCCCTTCGCCGCATGCGCCGCGAGGGCCTCGCCAACGTCCGCCTCTACCACGGCCAG
GGCCCCTTCGCCCTTCGGAACCTGGTCTTGCCGGGGACCCTGGACCAGGTCATTGTCAACTTCCCCGACCCCTGGCCCAA
GAAGCGGCACCAGGAGCGGCGCCTCCTGCGGGAGGCCTTCTTCCGCAGGCTCTCCACCCGCCTGAAGCCCGGGGGGAGCC
TCCTCCTCACCACGGACCACGAGGAGTACTTCCGCTTCGCCCTGGAGGAGGCGGAGCGGACCGGGCTCTACCGGGTGGAG
GTCCGGCCGCCCCCCGAGGCCCACCTCCGCACCAAGTACGCCCTAAAGTGGAAGGAGGCGGGGCGGGCCTTCTTCCACGC
CGCCTTCATTAAGCTTCGCGAAGACCCCGCCCCCTGGCCCCCCTTAAGGAGGTACGACGTGGCCCACGCCCTGCTTTCCG
GCGAGCTGCCCCAAGACCTGGCCCTGGAGAAGACCCCCGTGCGCCTGAAGGAAGGGGTCGCCGTCTTCCTGGAGGTGGCC
CGGGGCAAGGAGGGGTTTTACGTCCTCACCCACGTGGAGGAGGAGGACCTGACCCAGGACCTGCTCCTCGAGGTCCGCAA
AAGCGCCCGGGGGGTCTACGCCGGGGTGAGCCGCTTCGGCAGCCCCCTCATCACCGAGGCCGTCAAGGGGGCGGTGCGGG
CCCTGGTGGACCGGCTCGAGGCCCACGGGCTGGAGGTGGTCCAGGACCACACCTGA

Upstream 100 bases:

>100_bases
TTGACCTTGCACCCCAGGGTACGGAAGGCGGCGCGCATCCTTCTGATTTTGCGCCGGGGGGAAGGCCCCGTCAAGGACGG
AGGCCGTATAATCGGCAACC

Downstream 100 bases:

>100_bases
GGCCGGGTAAGATAAGCCCATGGACCTGCCTCCCCGCACCGGCTCCCTCAAGTGGGGCACCTACCCCGAGGACGTCCTCC
CCCTCTGGGTGGCGGACATG

Product: methyltransferase

Products: NA

Alternate protein names: tRNA(m7G46)-methyltransferase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MLVVPARLHRWPPEVQDLFGREGPLVLEIGFGDGRFTAELARSRPDWLVLGAEVSAASVLRALRRMRREGLANVRLYHGQ
GPFALRNLVLPGTLDQVIVNFPDPWPKKRHQERRLLREAFFRRLSTRLKPGGSLLLTTDHEEYFRFALEEAERTGLYRVE
VRPPPEAHLRTKYALKWKEAGRAFFHAAFIKLREDPAPWPPLRRYDVAHALLSGELPQDLALEKTPVRLKEGVAVFLEVA
RGKEGFYVLTHVEEEDLTQDLLLEVRKSARGVYAGVSRFGSPLITEAVKGAVRALVDRLEAHGLEVVQDHT

Sequences:

>Translated_311_residues
MLVVPARLHRWPPEVQDLFGREGPLVLEIGFGDGRFTAELARSRPDWLVLGAEVSAASVLRALRRMRREGLANVRLYHGQ
GPFALRNLVLPGTLDQVIVNFPDPWPKKRHQERRLLREAFFRRLSTRLKPGGSLLLTTDHEEYFRFALEEAERTGLYRVE
VRPPPEAHLRTKYALKWKEAGRAFFHAAFIKLREDPAPWPPLRRYDVAHALLSGELPQDLALEKTPVRLKEGVAVFLEVA
RGKEGFYVLTHVEEEDLTQDLLLEVRKSARGVYAGVSRFGSPLITEAVKGAVRALVDRLEAHGLEVVQDHT
>Mature_311_residues
MLVVPARLHRWPPEVQDLFGREGPLVLEIGFGDGRFTAELARSRPDWLVLGAEVSAASVLRALRRMRREGLANVRLYHGQ
GPFALRNLVLPGTLDQVIVNFPDPWPKKRHQERRLLREAFFRRLSTRLKPGGSLLLTTDHEEYFRFALEEAERTGLYRVE
VRPPPEAHLRTKYALKWKEAGRAFFHAAFIKLREDPAPWPPLRRYDVAHALLSGELPQDLALEKTPVRLKEGVAVFLEVA
RGKEGFYVLTHVEEEDLTQDLLLEVRKSARGVYAGVSRFGSPLITEAVKGAVRALVDRLEAHGLEVVQDHT

Specific function: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA [H]

COG id: COG0220

COG function: function code R; Predicted S-adenosylmethionine-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TrmB family [H]

Homologues:

Organism=Escherichia coli, GI1789330, Length=181, Percent_Identity=31.4917127071823, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003358 [H]

Pfam domain/function: PF02390 Methyltransf_4 [H]

EC number: =2.1.1.33 [H]

Molecular weight: Translated: 35375; Mature: 35375

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVVPARLHRWPPEVQDLFGREGPLVLEIGFGDGRFTAELARSRPDWLVLGAEVSAASVL
CEEECHHHHCCCCHHHHHCCCCCCEEEEEECCCCCHHHHHHHCCCCEEEEECCCCHHHHH
RALRRMRREGLANVRLYHGQGPFALRNLVLPGTLDQVIVNFPDPWPKKRHQERRLLREAF
HHHHHHHHCCCCCEEEEECCCCHHHHHCCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHH
FRRLSTRLKPGGSLLLTTDHEEYFRFALEEAERTGLYRVEVRPPPEAHLRTKYALKWKEA
HHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHEEEHHHH
GRAFFHAAFIKLREDPAPWPPLRRYDVAHALLSGELPQDLALEKTPVRLKEGVAVFLEVA
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHH
RGKEGFYVLTHVEEEDLTQDLLLEVRKSARGVYAGVSRFGSPLITEAVKGAVRALVDRLE
CCCCCEEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AHGLEVVQDHT
HCCCHHHCCCC
>Mature Secondary Structure
MLVVPARLHRWPPEVQDLFGREGPLVLEIGFGDGRFTAELARSRPDWLVLGAEVSAASVL
CEEECHHHHCCCCHHHHHCCCCCCEEEEEECCCCCHHHHHHHCCCCEEEEECCCCHHHHH
RALRRMRREGLANVRLYHGQGPFALRNLVLPGTLDQVIVNFPDPWPKKRHQERRLLREAF
HHHHHHHHCCCCCEEEEECCCCHHHHHCCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHH
FRRLSTRLKPGGSLLLTTDHEEYFRFALEEAERTGLYRVEVRPPPEAHLRTKYALKWKEA
HHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHEEEHHHH
GRAFFHAAFIKLREDPAPWPPLRRYDVAHALLSGELPQDLALEKTPVRLKEGVAVFLEVA
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHH
RGKEGFYVLTHVEEEDLTQDLLLEVRKSARGVYAGVSRFGSPLITEAVKGAVRALVDRLE
CCCCCEEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AHGLEVVQDHT
HCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA