Click here to switch to the map view.

The map label for this gene is rnr [C]

Identifier: 55981503

GI number: 55981503

Start: 1459112

End: 1460908

Strand: Direct

Name: rnr [C]

Synonym: TTHA1534

Alternate gene names: 55981503

Gene position: 1459112-1460908 (Clockwise)

Preceding gene: 55981502

Following gene: 55981505

Centisome position: 78.88

GC content: 72.18

Gene sequence:

>1797_bases
ATGGCCGTCAAGCAAGCCCTTGTCGTCTACAAAGGCAAACCCGCCCTCGCCGAGGAGAAGGGGGGCCGCTTGGAGCTCAC
GCTGGAAGGAGGCGCAAGGCTGAGGGTGCGTCCCAAGGACGTCCTCTTCCTCCACCCGGGGCCCGCCTCCTTAGGCCTGA
AGGTGCCCGAGGGAGAGGAGGAGGCCGCCTGGGAACTCCTGGAGGGGCAGACGGTGAGCCTTAGGGAGCTCGCCGAGCTG
GTCTACGGGGCCTACACCCCGGAGGCCGCTCTGGGCGCCTACCTCCTCGCCCAGAAGGGGGAGCGCTTCGTCCTCGAGGG
GGAAGGGGTCCGGGCCCGCACCCGGGAGGAGCTTCGGGCCTTAGAGGAGGCGGAAAGGAAGCGGGCCGAGCGGGAACGGG
CCTTCCAGGAGGCCCTGAAGCGCCTAAAGGAGGGAAGCCCCGCCCCCGAGGACCGCCCCCTCCTCGCCGAGGTGGAGGCC
CTGGCCCGGGGGGAGAGGAAGGAAAGCCCCGTCCTCCGGGCCCTGAACCTCCCCGAAACCCCCGAGGCGGCCCACGCCTT
CCTCCTCCGCCTGGGCCTTTGGCAAAGGGAAAACCCCCACCCAAGGAGGCTCGGCCTTCCCCTCCAGCCCCCGGACCTCC
CCGCCCCACCCCTCCCCGAGGAGGACCGGGTGGACCTCACCCACCTCCCCGCCTTCGCCATAGACGACGAGGGAAGCCAG
GACCCCGACGACGCCGTCTTCGCCGAGAAGGTGGAAGGGGGCTTCCGCCTCTTCGTCCACGTGGCCGACGTGGCCGCCCT
CGTCCCCCCCAAAAGCCCCCTGGACGAGGAGGCCCTGCGCCGGGGGGCGAACCTCTACCTCCCCGAGGGAACCGTGCCCA
TGCTCCCCCCCGCCGTCACCGAGGCCCTCGGCCTGGGCCTAAGGGAGGTCTCCCCGGCCCTCACCTTTGAGCTATGGGTC
TCGGAGGAGGGGGAGCTTCTGGAGGAGAGGGTCTACCCCTCCTGGGTACGGGTCACGCGCCTCACCTACCGGGAGGCCCT
GGGGGTGGAGGCCCTGAGGCCCCTGGAGGCCCTGGCGGAGGCCTTCCGGGCGAAGCGCCTCGCCGCGGGCGCCCTGGAGA
TCGCCCTCCCCGAGGTGAAGGTGCGGGTGGAGGGGGAGGAGGTCCGGATCACCCCCTTGCCCCCCTACCCAAGCCGCGTC
TGGGTGCGGGAGGCCATGCTCCTCGCCGGGTACGCCGCGGCCCACCTGGCGGTGCGGGAGGGGCTTCCCTTCCCCTTCGC
CACCCAGGAGGCCCCCGCAAGGCGGGTGGAGGGGGAGGGGCTTGCCGCCATGTGGGAGCAGCGGAAGGCCCTGAAGCGGG
CCCAGCTCAAGGCGGTGCCCGCCCCCCACAAGGGCTTAGGCCTTCCCCTCTACGCCCAGGTGACGAGCCCCCTAAGGCGC
TACCTGGACCTGGTGGCCCACCAGCAGCTCAGGGCCTGGCTCAAAGGGGAGAGGCCCCTCTCCCAGGCCGAGGTCCTGGA
AAGGGTGGGGGCGGCGGAGGCGGTGGCCGACCTGGTGCGGGAGGCGGAGCGCAAGAGCAAGCTCCACTGGACCCTCCTCC
ACCTCGAGGCCAAGGGTTACGAGGGGCCCGGCGTCCTGGTGGAAAGGCGGGGGGGGCAGGGGGTCTTCCTCCTCCCCGAG
CTCGGGCTTTCCGCCCAGGTGGCCCTGCCCAAGGCCCTTCCCCTGAACGCCGAGGCCCGCCTCCGCTTCCTGGAGGCGGA
CCTTCCGGCCCTCGAGGCCCGCTTCGCCCTGGTCTAG

Upstream 100 bases:

>100_bases
ACGGGCTTGTCGTCCTGCCTAAGCCCCAACAAAAGGATTGAGGCCGGGGACCCGCTACGCAGTTCCCGGCCACCCAGGCT
TCATTATAAGGAGGACACCC

Downstream 100 bases:

>100_bases
GCGCCGCATCAGGCTCGGGGCCATGCCGGGCCCCATGCCGGCCCAAGCCGGCATGGGGTGGCCTTAGTCTTCCCCTTGGG
CCTTGGTGAAGCCGGGCTCG

Product: ribonuclease II family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MAVKQALVVYKGKPALAEEKGGRLELTLEGGARLRVRPKDVLFLHPGPASLGLKVPEGEEEAAWELLEGQTVSLRELAEL
VYGAYTPEAALGAYLLAQKGERFVLEGEGVRARTREELRALEEAERKRAERERAFQEALKRLKEGSPAPEDRPLLAEVEA
LARGERKESPVLRALNLPETPEAAHAFLLRLGLWQRENPHPRRLGLPLQPPDLPAPPLPEEDRVDLTHLPAFAIDDEGSQ
DPDDAVFAEKVEGGFRLFVHVADVAALVPPKSPLDEEALRRGANLYLPEGTVPMLPPAVTEALGLGLREVSPALTFELWV
SEEGELLEERVYPSWVRVTRLTYREALGVEALRPLEALAEAFRAKRLAAGALEIALPEVKVRVEGEEVRITPLPPYPSRV
WVREAMLLAGYAAAHLAVREGLPFPFATQEAPARRVEGEGLAAMWEQRKALKRAQLKAVPAPHKGLGLPLYAQVTSPLRR
YLDLVAHQQLRAWLKGERPLSQAEVLERVGAAEAVADLVREAERKSKLHWTLLHLEAKGYEGPGVLVERRGGQGVFLLPE
LGLSAQVALPKALPLNAEARLRFLEADLPALEARFALV

Sequences:

>Translated_598_residues
MAVKQALVVYKGKPALAEEKGGRLELTLEGGARLRVRPKDVLFLHPGPASLGLKVPEGEEEAAWELLEGQTVSLRELAEL
VYGAYTPEAALGAYLLAQKGERFVLEGEGVRARTREELRALEEAERKRAERERAFQEALKRLKEGSPAPEDRPLLAEVEA
LARGERKESPVLRALNLPETPEAAHAFLLRLGLWQRENPHPRRLGLPLQPPDLPAPPLPEEDRVDLTHLPAFAIDDEGSQ
DPDDAVFAEKVEGGFRLFVHVADVAALVPPKSPLDEEALRRGANLYLPEGTVPMLPPAVTEALGLGLREVSPALTFELWV
SEEGELLEERVYPSWVRVTRLTYREALGVEALRPLEALAEAFRAKRLAAGALEIALPEVKVRVEGEEVRITPLPPYPSRV
WVREAMLLAGYAAAHLAVREGLPFPFATQEAPARRVEGEGLAAMWEQRKALKRAQLKAVPAPHKGLGLPLYAQVTSPLRR
YLDLVAHQQLRAWLKGERPLSQAEVLERVGAAEAVADLVREAERKSKLHWTLLHLEAKGYEGPGVLVERRGGQGVFLLPE
LGLSAQVALPKALPLNAEARLRFLEADLPALEARFALV
>Mature_597_residues
AVKQALVVYKGKPALAEEKGGRLELTLEGGARLRVRPKDVLFLHPGPASLGLKVPEGEEEAAWELLEGQTVSLRELAELV
YGAYTPEAALGAYLLAQKGERFVLEGEGVRARTREELRALEEAERKRAERERAFQEALKRLKEGSPAPEDRPLLAEVEAL
ARGERKESPVLRALNLPETPEAAHAFLLRLGLWQRENPHPRRLGLPLQPPDLPAPPLPEEDRVDLTHLPAFAIDDEGSQD
PDDAVFAEKVEGGFRLFVHVADVAALVPPKSPLDEEALRRGANLYLPEGTVPMLPPAVTEALGLGLREVSPALTFELWVS
EEGELLEERVYPSWVRVTRLTYREALGVEALRPLEALAEAFRAKRLAAGALEIALPEVKVRVEGEEVRITPLPPYPSRVW
VREAMLLAGYAAAHLAVREGLPFPFATQEAPARRVEGEGLAAMWEQRKALKRAQLKAVPAPHKGLGLPLYAQVTSPLRRY
LDLVAHQQLRAWLKGERPLSQAEVLERVGAAEAVADLVREAERKSKLHWTLLHLEAKGYEGPGVLVERRGGQGVFLLPEL
GLSAQVALPKALPLNAEARLRFLEADLPALEARFALV

Specific function: 3'-5'Exoribonuclease That Participates In An Essential Cell Function. Acts Nonspecifically On Poly(A), Poly(U) And Ribosomal RNAs. Required For The Expression Of VIrulence Genes In Enteroinvasive Strains Of E.Coli. [C]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonuclease II (RNB) family [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=413, Percent_Identity=26.3922518159806, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI190014625, Length=413, Percent_Identity=26.3922518159806, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI134288890, Length=369, Percent_Identity=27.9132791327913, Blast_Score=91, Evalue=4e-18,
Organism=Escherichia coli, GI87082383, Length=343, Percent_Identity=30.0291545189504, Blast_Score=108, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI212645896, Length=429, Percent_Identity=26.8065268065268, Blast_Score=92, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324552, Length=351, Percent_Identity=29.3447293447293, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24649634, Length=431, Percent_Identity=27.6102088167053, Blast_Score=107, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001900
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00773 RNB [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 65897; Mature: 65766

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKQALVVYKGKPALAEEKGGRLELTLEGGARLRVRPKDVLFLHPGPASLGLKVPEGEE
CCCCCEEEEECCCCCCHHCCCCEEEEEECCCCEEEECCCCEEEECCCCCCCCCCCCCCCH
EAAWELLEGQTVSLRELAELVYGAYTPEAALGAYLLAQKGERFVLEGEGVRARTREELRA
HHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH
LEEAERKRAERERAFQEALKRLKEGSPAPEDRPLLAEVEALARGERKESPVLRALNLPET
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHEECCCCCC
PEAAHAFLLRLGLWQRENPHPRRLGLPLQPPDLPAPPLPEEDRVDLTHLPAFAIDDEGSQ
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEECCCCCC
DPDDAVFAEKVEGGFRLFVHVADVAALVPPKSPLDEEALRRGANLYLPEGTVPMLPPAVT
CCCHHHHHHHHCCCEEEEEEHHHHHHHCCCCCCCCHHHHHCCCCEECCCCCCCCCCHHHH
EALGLGLREVSPALTFELWVSEEGELLEERVYPSWVRVTRLTYREALGVEALRPLEALAE
HHHCCCHHHCCCCEEEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
AFRAKRLAAGALEIALPEVKVRVEGEEVRITPLPPYPSRVWVREAMLLAGYAAAHLAVRE
HHHHHHHHCCHHEEECCCEEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHC
GLPFPFATQEAPARRVEGEGLAAMWEQRKALKRAQLKAVPAPHKGLGLPLYAQVTSPLRR
CCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
YLDLVAHQQLRAWLKGERPLSQAEVLERVGAAEAVADLVREAERKSKLHWTLLHLEAKGY
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCEEEEEEEEEECCC
EGPGVLVERRGGQGVFLLPELGLSAQVALPKALPLNAEARLRFLEADLPALEARFALV
CCCCEEEEECCCCEEEEECCCCCCEEEECCCCCCCCHHHHHEEECCCCCHHHHHEECC
>Mature Secondary Structure 
AVKQALVVYKGKPALAEEKGGRLELTLEGGARLRVRPKDVLFLHPGPASLGLKVPEGEE
CCCCEEEEECCCCCCHHCCCCEEEEEECCCCEEEECCCCEEEECCCCCCCCCCCCCCCH
EAAWELLEGQTVSLRELAELVYGAYTPEAALGAYLLAQKGERFVLEGEGVRARTREELRA
HHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH
LEEAERKRAERERAFQEALKRLKEGSPAPEDRPLLAEVEALARGERKESPVLRALNLPET
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHEECCCCCC
PEAAHAFLLRLGLWQRENPHPRRLGLPLQPPDLPAPPLPEEDRVDLTHLPAFAIDDEGSQ
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEECCCCCC
DPDDAVFAEKVEGGFRLFVHVADVAALVPPKSPLDEEALRRGANLYLPEGTVPMLPPAVT
CCCHHHHHHHHCCCEEEEEEHHHHHHHCCCCCCCCHHHHHCCCCEECCCCCCCCCCHHHH
EALGLGLREVSPALTFELWVSEEGELLEERVYPSWVRVTRLTYREALGVEALRPLEALAE
HHHCCCHHHCCCCEEEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
AFRAKRLAAGALEIALPEVKVRVEGEEVRITPLPPYPSRVWVREAMLLAGYAAAHLAVRE
HHHHHHHHCCHHEEECCCEEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHC
GLPFPFATQEAPARRVEGEGLAAMWEQRKALKRAQLKAVPAPHKGLGLPLYAQVTSPLRR
CCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
YLDLVAHQQLRAWLKGERPLSQAEVLERVGAAEAVADLVREAERKSKLHWTLLHLEAKGY
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCEEEEEEEEEECCC
EGPGVLVERRGGQGVFLLPELGLSAQVALPKALPLNAEARLRFLEADLPALEARFALV
CCCCEEEEECCCCEEEEECCCCCCEEEECCCCCCCCHHHHHEEECCCCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]