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The map label for this gene is soxA [H]

Identifier: 55981505

GI number: 55981505

Start: 1462537

End: 1463286

Strand: Direct

Name: soxA [H]

Synonym: TTHA1536

Alternate gene names: 55981505

Gene position: 1462537-1463286 (Clockwise)

Preceding gene: 55981503

Following gene: 55981507

Centisome position: 79.07

GC content: 69.07

Gene sequence:

>750_bases
GTGGCCCGGGTGGTCGTGGTGGGGGCGGGGATCGTAGGGGCGGCCTCGGCCTACCGCCTGGCGGAAAAGGGGCTTAGGGT
CTTGGTCCTGGAGAAGGAGGCCACCTACGCCCAAGGGTCCACCGGGAAAAGCGCCGCCGGGGTGCGGGTGCAGTTCTCCG
AGCCCTCGAACGTCCTCCTCTCCTACCGTTCCATCCTGGAGTACCGGGAAATCCCCGAGGCCGCCTATCGGCCTACGGGC
TACCTCTTCCTGGTGCCCGAGGCCCAGGCCGAGGCCCAGGAAGAGGCCCTAAGGGTGCAGAAGGCCCTGGGGGTCCCCGT
GGAGAAGCTCTCCCTGGCGGAGGCCCAAAGGAAGGTGCCCTTTAGGGAGGAGGGCCTGGCCTACGCCACCTTCGGCCCCA
TGGACGGGACCATAGACCCCCACGGGGCCACGGCCTATTACCTCAGGGAGGCCAGGCGCCTGGGGGCGGAGGTGCGCTTT
TCCGAGCCCCTCCTTAGGGCCGAGCGCCGGGAGGGTGTGTGGCGGGTGGAGACCCCGAAAGGGCTGTACGAGGCCCCTTT
CCTCCTCCTGTGCACCGGGGCCTGGACAGGGGAGGTGGGGCGAACCTTGGGCCTGGAGATCCCCGTACAGCCGGTGCGCC
GCATGGTCTTCGCCACCGCCCCTACGCCATTTCCCCACGCCTTTCCCCTCACCGTGGACCTCGGCACGGGCTTCTACTTC
CGCTCCGAGGGAAGCCGCCTGGTCAAGTAG

Upstream 100 bases:

>100_bases
CCGGTTTCCGTGGTGATCAGGGGCATGGGTTCACCTCCGGGGGCGGAATCGCCCCCCTTTACACTACACCACGGGGCTTG
AGGCCTTGTAAACTCGGGGC

Downstream 100 bases:

>100_bases
AGCGCACATTAGCGCACTCCGGCCCCCCACCAGGATGAGGACCTAAGCCTCCCCTCCACCCCTCCCACGATCCCCCGAAG
AGGATGGGCTTGAGGAGAGA

Product: oxidoreductase-like protein

Products: NA

Alternate protein names: MSOX [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MARVVVVGAGIVGAASAYRLAEKGLRVLVLEKEATYAQGSTGKSAAGVRVQFSEPSNVLLSYRSILEYREIPEAAYRPTG
YLFLVPEAQAEAQEEALRVQKALGVPVEKLSLAEAQRKVPFREEGLAYATFGPMDGTIDPHGATAYYLREARRLGAEVRF
SEPLLRAERREGVWRVETPKGLYEAPFLLLCTGAWTGEVGRTLGLEIPVQPVRRMVFATAPTPFPHAFPLTVDLGTGFYF
RSEGSRLVK

Sequences:

>Translated_249_residues
MARVVVVGAGIVGAASAYRLAEKGLRVLVLEKEATYAQGSTGKSAAGVRVQFSEPSNVLLSYRSILEYREIPEAAYRPTG
YLFLVPEAQAEAQEEALRVQKALGVPVEKLSLAEAQRKVPFREEGLAYATFGPMDGTIDPHGATAYYLREARRLGAEVRF
SEPLLRAERREGVWRVETPKGLYEAPFLLLCTGAWTGEVGRTLGLEIPVQPVRRMVFATAPTPFPHAFPLTVDLGTGFYF
RSEGSRLVK
>Mature_248_residues
ARVVVVGAGIVGAASAYRLAEKGLRVLVLEKEATYAQGSTGKSAAGVRVQFSEPSNVLLSYRSILEYREIPEAAYRPTGY
LFLVPEAQAEAQEEALRVQKALGVPVEKLSLAEAQRKVPFREEGLAYATFGPMDGTIDPHGATAYYLREARRLGAEVRFS
EPLLRAERREGVWRVETPKGLYEAPFLLLCTGAWTGEVGRTLGLEIPVQPVRRMVFATAPTPFPHAFPLTVDLGTGFYFR
SEGSRLVK

Specific function: Catalyzes the oxidative demethylation of sarcosine [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MSOX/MTOX family. MSOX subfamily [H]

Homologues:

Organism=Homo sapiens, GI8923708, Length=264, Percent_Identity=31.4393939393939, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI24797151, Length=266, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI197927446, Length=262, Percent_Identity=30.1526717557252, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI21361378, Length=262, Percent_Identity=30.1526717557252, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32563613, Length=249, Percent_Identity=28.9156626506024, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129729, Length=276, Percent_Identity=29.7101449275362, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571104, Length=265, Percent_Identity=29.811320754717, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI20130091, Length=261, Percent_Identity=25.6704980842912, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002204
- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 27318; Mature: 27187

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVVVVGAGIVGAASAYRLAEKGLRVLVLEKEATYAQGSTGKSAAGVRVQFSEPSNVLL
CCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCHHHH
SYRSILEYREIPEAAYRPTGYLFLVPEAQAEAQEEALRVQKALGVPVEKLSLAEAQRKVP
HHHHHHHHHHCCHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
FREEGLAYATFGPMDGTIDPHGATAYYLREARRLGAEVRFSEPLLRAERREGVWRVETPK
CHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEECCC
GLYEAPFLLLCTGAWTGEVGRTLGLEIPVQPVRRMVFATAPTPFPHAFPLTVDLGTGFYF
CCCCCCEEEEEECCCCCCCCCEECCCCCHHHHHHHEEEECCCCCCCCEEEEEECCCCEEE
RSEGSRLVK
ECCCCCCCC
>Mature Secondary Structure 
ARVVVVGAGIVGAASAYRLAEKGLRVLVLEKEATYAQGSTGKSAAGVRVQFSEPSNVLL
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCHHHH
SYRSILEYREIPEAAYRPTGYLFLVPEAQAEAQEEALRVQKALGVPVEKLSLAEAQRKVP
HHHHHHHHHHCCHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
FREEGLAYATFGPMDGTIDPHGATAYYLREARRLGAEVRFSEPLLRAERREGVWRVETPK
CHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEECCC
GLYEAPFLLLCTGAWTGEVGRTLGLEIPVQPVRRMVFATAPTPFPHAFPLTVDLGTGFYF
CCCCCCEEEEEECCCCCCCCCEECCCCCHHHHHHHEEEECCCCCCCCEEEEEECCCCEEE
RSEGSRLVK
ECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]